The network for 'small molecule biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

small molecule biosynthetic process

The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.

Homo sapiens
Name Description Probability Func Analog Organism
DHCR7 7-dehydrocholesterol reductase 1.000
SC4MOL sterol-C4-methyl oxidase-like 0.999
FGF1 fibroblast growth factor 1 (acidic) 0.996
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) 0.988
APOA1 apolipoprotein A-I 0.985
FGFR2 fibroblast growth factor receptor 2 0.980
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.978
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 0.975
FDPS farnesyl diphosphate synthase 0.972
FGFR1 fibroblast growth factor receptor 1 0.967
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.962
HNF4A hepatocyte nuclear factor 4, alpha 0.961
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.957
SQLE squalene epoxidase 0.955
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.947
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.945
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase 0.922
MARS methionyl-tRNA synthetase 0.906
SREBF2 sterol regulatory element binding transcription factor 2 0.897
ACLY ATP citrate lyase 0.897
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.896
IDI1 isopentenyl-diphosphate delta isomerase 1 0.885
DHCR24 24-dehydrocholesterol reductase 0.877
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.875
ACAT2 acetyl-CoA acetyltransferase 2 0.817
ZFYVE9 zinc finger, FYVE domain containing 9 0.807
RXRA retinoid X receptor, alpha 0.797
C14orf1 chromosome 14 open reading frame 1 0.777
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) 0.773
NSDHL NAD(P) dependent steroid dehydrogenase-like 0.768
PRDX1 peroxiredoxin 1 0.745
CREBBP CREB binding protein 0.742
IL1R1 interleukin 1 receptor, type I 0.731
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.708
GGTLC1 gamma-glutamyltransferase light chain 1 0.658
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.632
INSIG1 insulin induced gene 1 0.629
LDLR low density lipoprotein receptor 0.622
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 0.619
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.612
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.577
MVD mevalonate (diphospho) decarboxylase 0.570
ALB albumin 0.562
CYP3A43 cytochrome P450, family 3, subfamily A, polypeptide 43 0.559
ALDOB aldolase B, fructose-bisphosphate 0.552
IL1B interleukin 1, beta 0.548
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.545
APOE apolipoprotein E 0.543
AKR1C3 aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II) 0.537
PGRMC1 progesterone receptor membrane component 1 0.508
RAB10 RAB10, member RAS oncogene family 0.488
GLYAT glycine-N-acyltransferase 0.476
HPD 4-hydroxyphenylpyruvate dioxygenase 0.461
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.459
HP haptoglobin 0.456
GCLC glutamate-cysteine ligase, catalytic subunit 0.452
GGT1 gamma-glutamyltransferase 1 0.434
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble 0.428
APOC2 apolipoprotein C-II 0.426
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.425
MAPT microtubule-associated protein tau 0.420
APOC1 apolipoprotein C-I 0.415
AARS alanyl-tRNA synthetase 0.410
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.408
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.408
AR androgen receptor 0.405
ZHX1 zinc fingers and homeoboxes 1 0.401
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.394
APOC3 apolipoprotein C-III 0.393
DLAT dihydrolipoamide S-acetyltransferase 0.389
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.377
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.373
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.368
FGF10 fibroblast growth factor 10 0.366
GCLM glutamate-cysteine ligase, modifier subunit 0.359
IL1RN interleukin 1 receptor antagonist 0.359
FGF2 fibroblast growth factor 2 (basic) 0.348
PINK1 PTEN induced putative kinase 1 0.345
MAT1A methionine adenosyltransferase I, alpha 0.340
COTL1 coactosin-like 1 (Dictyostelium) 0.338
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12 0.334
CA5A carbonic anhydrase VA, mitochondrial 0.326
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.326
TALDO1 transaldolase 1 0.326
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.322
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.317
FABP1 fatty acid binding protein 1, liver 0.317
FADS1 fatty acid desaturase 1 0.312
KLB klotho beta 0.310
TXN thioredoxin 0.310
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.309
TMEM97 transmembrane protein 97 0.296
FGF8 fibroblast growth factor 8 (androgen-induced) 0.292
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.290
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.289
GARS glycyl-tRNA synthetase 0.285
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 0.284
SC5DL sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like 0.277
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.275
ACACA acetyl-CoA carboxylase alpha 0.271
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
fat-2 Protein FAT-2 0.679
sptl-1 Protein SPTL-1 0.609
brp-1 Protein BRP-1 0.524
hpo-8 Protein HPO-8 0.478
fat-6 Protein FAT-6 0.443
elo-1 Protein ELO-1 0.435
metr-1 Protein METR-1 0.427
pmt-1 Protein PMT-1 0.421
fat-4 Protein FAT-4 0.372
elo-6 Protein ELO-6 0.286
sams-3 Protein SAMS-3 0.282
lmp-1 Protein LMP-1 0.219
mboa-3 Protein MBOA-3 0.209
pyk-2 Protein PYK-2 0.201
pod-2 Protein POD-2 0.173
elo-5 Protein ELO-5 0.165
cpi-2 Protein CPI-2 0.160
C34C12.8 Protein C34C12.8 0.155
elo-2 Protein ELO-2 0.148
ZK484.1 Protein ZK484.1 0.138
mel-32 Protein MEL-32 0.132
sur-5 Protein SUR-5 0.124
acs-17 Protein ACS-17 0.123
amt-4 Protein AMT-4 0.120
vab-3 Protein VAB-3 0.119
CELE_F44D12.9 Protein F44D12.9 0.117
pyc-1 Protein PYC-1 0.111
CELE_F17C11.6 Protein F17C11.6 0.106
sptl-2 Protein SPTL-2 0.099
C34B2.6 Protein C34B2.6 0.098
nlp-36 Protein NLP-36 0.098
cts-1 Protein CTS-1 0.097
rhr-1 Protein RHR-1 0.097
acl-6 Protein ACL-6 0.092
mtrr-1 Protein MTRR-1 0.091
dig-1 Protein DIG-1 0.090
F39B2.3 Protein F39B2.3 0.089
pes-9 Protein PES-9 0.086
cth-2 Protein CTH-2 0.085
itr-1 Protein ITR-1 0.083
M03B6.2 Protein M03B6.2 0.081
C44C1.5 Protein C44C1.5 0.081
F33D4.5 Protein F33D4.5 0.080
dhp-1 Protein DHP-1 0.080
CELE_Y53C10A.5 Protein Y53C10A.5 0.075
msra-1 Protein MSRA-1 0.073
CELE_ZK1320.2 Protein ZK1320.2 0.073
F22F7.1 Protein F22F7.1 0.073
D1005.1 Protein D1005.1 0.068
sptl-3 Protein SPTL-3 0.068
F13E6.5 Protein F13E6.5 0.067
crls-1 Protein CRLS-1 0.066
dct-18 Protein DCT-18 0.065
T28D9.3 Protein T28D9.3 0.065
cept-1 Protein CEPT-1 0.063
ugt-58 Protein UGT-58 0.063
CELE_T01B11.2 Protein T01B11.2 0.063
mrps-5 Protein MRPS-5 0.062
C03A3.2 Protein C03A3.2 0.062
lite-1 Protein LITE-1 0.062
zip-7 Protein ZIP-7 0.061
CELE_F25E5.8 Protein F25E5.8 0.061
CELE_F59C6.5 Protein F59C6.5 0.056
ftn-2 Protein FTN-2 0.056
gst-36 Protein GST-36 0.056
CELE_R02D3.1 Protein R02D3.1 0.056
F25G6.9 Protein F25G6.9 0.056
R02F2.5 Protein R02F2.5 0.055
acs-22 Protein ACS-22 0.055
CELE_ZK228.3 Protein ZK228.3 0.054
R07E3.4 Protein R07E3.4 0.054
CELE_F17C11.4 Protein F17C11.4 0.054
ugt-62 Protein UGT-62 0.053
CELE_F54F3.4 Protein F54F3.4 0.053
spp-8 Protein SPP-8 0.052
pyp-1 Protein PYP-1 0.052
act-5 Protein ACT-5 0.052
unc-42 Protein UNC-42 0.052
T25B9.9 Protein T25B9.9 0.052
CELE_F20G2.2 Protein F20G2.2 0.051
cpz-2 Protein CPZ-2 0.050
hex-1 Protein HEX-1 0.050
erd-2 Protein ERD-2 0.049
aldo-2 Protein ALDO-2 0.049
haly-1 Protein HALY-1 0.049
ugt-23 Protein UGT-23 0.049
pnk-1 Protein PNK-1 0.048
stim-1 Protein STIM-1 0.048
mrps-9 Protein MRPS-9 0.048
Y56A3A.6 Protein Y56A3A.6 0.048
mthf-1 Protein MTHF-1 0.048
alh-10 Protein ALH-10 0.047
pcyt-1 Protein PCYT-1 0.046
gpd-3 Protein GPD-3 0.045
E04A4.5 Protein E04A4.5 0.045
atf-5 Protein ATF-5 0.044
dhs-4 Protein DHS-4 0.044
fat-3 Protein FAT-3 0.044
F36G3.2 Protein F36G3.2 0.044
hsp-6 Protein HSP-6 0.044
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
apoa4 apolipoprotein A-IV 0.330
gata4 GATA-binding protein 4 0.146
elovl5 ELOVL family member 5, elongation of long chain fatty acids (yeast) 0.134
dct dopachrome tautomerase 0.085
mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 0.079
tyrp1b tyrosinase-related protein 1b 0.071
fsta follistatin a 0.069
gpia glucose phosphate isomerase a 0.063
sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.063
plcg1 phospholipase C, gamma 1 0.060
hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.055
slc4a2b solute carrier family 4, anion exchanger, member 2b 0.054
dio2 deiodinase, iodothyronine, type II 0.054
fabp10a fatty acid binding protein 10a, liver basic 0.053
cyp2y3 cytochrome P450, family 2, subfamily Y, polypeptide 3 0.051
mtp microsomal triglyceride transfer protein 0.050
mthfd2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.047
hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.046
cyp1a cytochrome P450, family 1, subfamily A 0.044
grn2 granulin 2 0.041
oclnb occludin b 0.039
esr2b estrogen receptor 2b 0.039
fetub fetuin B 0.039
fshr follicle stimulating hormone receptor 0.037
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.035
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.034
il8 interleukin 8 0.034
rag1 recombination activating gene 1 0.033
cldni claudin i 0.032
ar androgen receptor 0.031
zgc:64042 zgc:64042 0.031
tm4sf4 transmembrane 4 L six family member 4 0.030
zgc:110308 zgc:110308 0.030
acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.030
myh11a myosin, heavy polypeptide 11, smooth muscle a 0.030
fads2 fatty acid desaturase 2 0.029
lgmn legumain 0.029
hnf4a hepatocyte nuclear factor 4, alpha 0.029
mib mind bomb 0.028
cldn2 claudin 2 0.027
igf3 insulin-like growth factor 3 0.027
ptch2 patched 2 0.027
m17 IL-6 subfamily cytokine M17 0.026
gli1 GLI-Kruppel family member 1 0.026
hsd17b12b hydroxysteroid (17-beta) dehydrogenase 12b 0.026
star steroidogenic acute regulatory protein 0.025
ndufa4 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4 0.025
si:dkeyp-110g5.2 si:dkeyp-110g5.2 0.025
aldoca aldolase C, fructose-bisphosphate, a 0.025
inha inhibin, alpha 0.025
dzip1 DAZ interacting protein 1 0.024
mat1a methionine adenosyltransferase I, alpha 0.024
abcb5 ATP-binding cassette, sub-family B (MDR/TAP), member 5 0.024
pawrl PRKC, apoptosis, WT1, regulator like 0.024
wls wntless homolog (Drosophila) 0.023
zgc:101565 zgc:101565 0.023
acadl acyl-Coenzyme A dehydrogenase, long chain 0.023
zff9 zinc finger protein 9 0.023
aldob aldolase b, fructose-bisphosphate 0.023
cyp24a1 cytochrome P450, family 24, subfamily A, polypeptide 1 0.022
valopa vertebrate ancient long opsin a 0.022
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.022
mpz myelin protein zero 0.022
wnt3 wingless-type MMTV integration site family, member 3 0.022
cx27.5 connexin 27.5 0.022
nr1i2 nuclear receptor subfamily 1, group I, member 2 0.022
gata6 GATA-binding protein 6 0.022
wu:fb63c04 wu:fb63c04 0.022
ins preproinsulin 0.021
dharma dharma 0.021
prl prolactin 0.021
paqr7b progestin and adipoQ receptor family member VII, b 0.021
cyp19a1a cytochrome P450, family 19, subfamily A, polypeptide 1a 0.021
esr1 estrogen receptor 1 0.020
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.020
zgc:64133 zgc:64133 0.020
zgc:92360 zgc:92360 0.020
si:ch211-93f2.1 si:ch211-93f2.1 0.020
axin1 axin 1 0.020
polr2d polymerase (RNA) II (DNA directed) polypeptide D 0.020
shbg sex hormone binding globulin 0.019
rest RE1-silencing transcription factor 0.019
slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 0.019
gnrh2 gonadotropin-releasing hormone 2 0.019
apoa1 apolipoprotein A-I 0.019
dhrs9 dehydrogenase/reductase (SDR family) member 9 0.019
rgrb retinal G protein coupled receptor b 0.018
lamc1 laminin, gamma 1 0.018
hsd17b1 hydroxysteroid (17-beta) dehydrogenase 1 0.018
gata5 GATA-binding protein 5 0.018
zgc:66382 zgc:66382 0.018
supt6h suppressor of Ty 6 homolog 0.018
tk2 thymidine kinase 2, mitochondrial 0.018
irx2a iroquois homeobox protein 2, a 0.017
slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 0.017
hmx2 H6 family homeobox 2 0.017
ivd isovaleryl Coenzyme A dehydrogenase 0.017
hsd3b7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 0.016
lamb2 laminin, beta 2 (laminin S) 0.016
ckbb creatine kinase, brain b 0.016
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
dib disembodied 0.575
Fatp Fatty acid (long chain) transport protein 0.474
Cyp12d1-p CG30489 gene product from transcript CG30489-RA 0.416
Ugt35a UDP-glycosyltransferase 35a 0.385
CG30008 CG30008 gene product from transcript CG30008-RA 0.357
CG18609 CG18609 gene product from transcript CG18609-RA 0.278
Sc2 CG10849 gene product from transcript CG10849-RA 0.262
GstE6 Glutathione S transferase E6 0.217
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.215
Hcf Host cell factor 0.198
Cyp6g1 CG8453 gene product from transcript CG8453-RA 0.191
Yp2 Yolk protein 2 0.181
Nlp Nucleoplasmin 0.176
Tps1 Trehalose-6-phosphate synthase 1 0.171
sad shadow 0.162
CG3011 CG3011 gene product from transcript CG3011-RA 0.157
CG15531 CG15531 gene product from transcript CG15531-RB 0.156
CG7910 CG7910 gene product from transcript CG7910-RA 0.154
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.153
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.148
Cyp4ac1 CG14032 gene product from transcript CG14032-RA 0.147
CG9458 CG9458 gene product from transcript CG9458-RA 0.146
sog short gastrulation 0.143
Cyp12e1 CG14680 gene product from transcript CG14680-RC 0.140
CG16904 CG16904 gene product from transcript CG16904-RA 0.138
CG11255 CG11255 gene product from transcript CG11255-RA 0.135
CG6660 CG6660 gene product from transcript CG6660-RA 0.125
sro shroud 0.119
shd shade 0.118
CG1907 CG1907 gene product from transcript CG1907-RA 0.118
Hn Henna 0.116
Herp Homocysteine-induced endoplasmic reticulum protein 0.114
Cyp12d1-d CG33503 gene product from transcript CG33503-RA 0.114
Rpb4 CG33520 gene product from transcript CG33520-RF 0.113
CG6283 CG6283 gene product from transcript CG6283-RA 0.111
CG4020 CG4020 gene product from transcript CG4020-RA 0.111
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.109
ftz-f1 ftz transcription factor 1 0.108
CG6834 CG6834 gene product from transcript CG6834-RA 0.107
CG1516 CG1516 gene product from transcript CG1516-RP 0.099
RpS3 Ribosomal protein S3 0.098
CG12672 CG12672 gene product from transcript CG12672-RA 0.097
Cat Catalase 0.096
GstE3 Glutathione S transferase E3 0.094
CG2064 CG2064 gene product from transcript CG2064-RA 0.094
trx trithorax 0.090
Cyp6a9 Cytochrome P450-6a9 0.090
CG8036 CG8036 gene product from transcript CG8036-RB 0.088
CG10863 CG10863 gene product from transcript CG10863-RA 0.083
yip2 yippee interacting protein 2 0.082
ade5 CG3989 gene product from transcript CG3989-RA 0.081
CG14820 CG14820 gene product from transcript CG14820-RA 0.080
CG11198 CG11198 gene product from transcript CG11198-RB 0.078
Cyp1 Cyclophilin 1 0.077
CG1927 CG1927 gene product from transcript CG1927-RA 0.074
Yp3 Yolk protein 3 0.074
CG12264 CG12264 gene product from transcript CG12264-RA 0.072
CG14837 CG14837 gene product from transcript CG14837-RC 0.072
CG11147 CG11147 gene product from transcript CG11147-RA 0.072
CG7979 CG7979 gene product from transcript CG7979-RA 0.070
Cpr100A Cuticular protein 100A 0.070
nvd neverland 0.069
Adh Alcohol dehydrogenase 0.069
tll tailless 0.068
AcCoAS Acetyl Coenzyme A synthase 0.066
myoglianin CG1838 gene product from transcript CG1838-RD 0.066
Tret1-1 Trehalose transporter 1-1 0.064
kkv krotzkopf verkehrt 0.063
cl clot 0.062
CG1443 CG1443 gene product from transcript CG1443-RA 0.062
sr stripe 0.062
CG13091 CG13091 gene product from transcript CG13091-RA 0.062
slpr slipper 0.061
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.061
laza lazaro 0.060
Hr96 Hormone receptor-like in 96 0.060
m-cup mann-cup 0.060
slam slow as molasses 0.055
insc inscuteable 0.055
alpha-Est7 alpha-Esterase-7 0.055
CG9990 CG9990 gene product from transcript CG9990-RA 0.054
CdsA CDP diglyceride synthetase 0.054
CG11327 CG11327 gene product from transcript CG11327-RA 0.054
wal walrus 0.052
ush u-shaped 0.052
Cyp4e2 Cytochrome P450-4e2 0.051
CG2765 CG2765 gene product from transcript CG2765-RE 0.050
Cyp4p1 Cytochrome P450-4p1 0.049
CG16926 CG16926 gene product from transcript CG16926-RA 0.048
l(1)G0334 lethal (1) G0334 0.048
eve even skipped 0.048
Sps2 Selenophosphate synthetase 2 0.048
Cyp28a5 CG8864 gene product from transcript CG8864-RA 0.047
CG4572 CG4572 gene product from transcript CG4572-RD 0.047
Smg1 CG32743 gene product from transcript CG32743-RA 0.047
Tal CG2827 gene product from transcript CG2827-RA 0.046
rib ribbon 0.046
Cyt-b5-r Cytochrome b5-related 0.046
CG9391 CG9391 gene product from transcript CG9391-RA 0.046
CG9459 CG9459 gene product from transcript CG9459-RA 0.046
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 0.995
Cyp51 cytochrome P450, family 51 0.992
Pax2 paired box gene 2 0.982
Pax8 paired box gene 8 0.972
Sqle squalene epoxidase 0.963
Idi1 isopentenyl-diphosphate delta isomerase 0.942
Pten phosphatase and tensin homolog 0.931
Otc ornithine transcarbamylase 0.922
Sc4mol sterol-C4-methyl oxidase-like 0.902
Serpina1c serine (or cysteine) peptidase inhibitor, clade A, member 1C 0.872
Hpd 4-hydroxyphenylpyruvic acid dioxygenase 0.870
Dmgdh dimethylglycine dehydrogenase precursor 0.867
Prlr prolactin receptor 0.831
Rarg retinoic acid receptor, gamma 0.816
Dhcr7 7-dehydrocholesterol reductase 0.798
Dhcr24 24-dehydrocholesterol reductase 0.765
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.758
Prrx2 paired related homeobox 2 0.749
Nr1i2 nuclear receptor subfamily 1, group I, member 2 0.747
Wnt4 wingless-related MMTV integration site 4 0.740
Rxra retinoid X receptor alpha 0.738
Cps1 carbamoyl-phosphate synthetase 1 0.729
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 0.729
Esr1 estrogen receptor 1 (alpha) 0.720
Thrb thyroid hormone receptor beta 0.702
Apoa1 apolipoprotein A-I 0.686
Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 0.683
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.664
Slc27a5 solute carrier family 27 (fatty acid transporter), member 5 0.661
Cyp2c29 cytochrome P450, family 2, subfamily c, polypeptide 29 0.661
Scd1 stearoyl-Coenzyme A desaturase 1 0.660
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.654
Aldob aldolase B, fructose-bisphosphate 0.640
Akr1c6 aldo-keto reductase family 1, member C6 0.639
Sc5d sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog (S. cerevisae) 0.636
Cyp2d10 cytochrome P450, family 2, subfamily d, polypeptide 10 0.634
Bmp7 bone morphogenetic protein 7 0.632
Lss lanosterol synthase 0.632
G6pc glucose-6-phosphatase, catalytic 0.627
Cyp3a25 cytochrome P450, family 3, subfamily a, polypeptide 25 0.620
Rarb retinoic acid receptor, beta 0.611
Asgr2 asialoglycoprotein receptor 2 0.610
Lepr leptin receptor 0.593
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.593
Aadat aminoadipate aminotransferase 0.588
Mup3 major urinary protein 3 0.585
Rdh7 retinol dehydrogenase 7 0.584
Serpina6 serine (or cysteine) peptidase inhibitor, clade A, member 6 0.581
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.578
Slc12a1 solute carrier family 12, member 1 0.568
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 0.567
Cyp2d26 cytochrome P450, family 2, subfamily d, polypeptide 26 0.562
Ces1c carboxylesterase 1C 0.559
F13b coagulation factor XIII, beta subunit 0.558
Fyn Fyn proto-oncogene 0.557
F12 coagulation factor XII (Hageman factor) 0.553
Srebf2 sterol regulatory element binding factor 2 0.548
Otx2 orthodenticle homolog 2 (Drosophila) 0.546
Fasn fatty acid synthase 0.545
Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 0.538
Cyp2c38 cytochrome P450, family 2, subfamily c, polypeptide 38 0.536
Per2 period homolog 2 (Drosophila) 0.534
Cyp2a12 cytochrome P450, family 2, subfamily a, polypeptide 12 0.534
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 0.530
Acly ATP citrate lyase 0.528
Uox urate oxidase 0.520
Cyp2b9 cytochrome P450, family 2, subfamily b, polypeptide 9 0.519
Lhx1 LIM homeobox protein 1 0.517
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 0.516
Akr1d1 aldo-keto reductase family 1, member D1 0.507
Timd2 T-cell immunoglobulin and mucin domain containing 2 0.498
Gclm glutamate-cysteine ligase, modifier subunit 0.493
Ldlr low density lipoprotein receptor 0.491
Phyh phytanoyl-CoA hydroxylase 0.486
Smo smoothened homolog (Drosophila) 0.482
Lhx3 LIM homeobox protein 3 0.479
Htt huntingtin 0.475
Agxt alanine-glyoxylate aminotransferase 0.469
Cyp2d9 cytochrome P450, family 2, subfamily d, polypeptide 9 0.469
Cry2 cryptochrome 2 (photolyase-like) 0.464
Apob apolipoprotein B 0.462
Kng1 kininogen 1 0.462
F2 coagulation factor II 0.460
Abcc6 ATP-binding cassette, sub-family C (CFTR/MRP), member 6 0.456
Apoa5 apolipoprotein A-V 0.443
Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.441
Ahsg alpha-2-HS-glycoprotein 0.441
Elovl3 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3 0.440
Cyp2c70 cytochrome P450, family 2, subfamily c, polypeptide 70 0.438
Scd2 stearoyl-Coenzyme A desaturase 2 0.430
Sult1b1 sulfotransferase family 1B, member 1 0.429
Apoe apolipoprotein E 0.426
Stard4 StAR-related lipid transfer (START) domain containing 4 0.425
Agtr1a angiotensin II receptor, type 1a 0.421
Pnp2 purine-nucleoside phosphorylase 2 0.417
Cyp2c54 cytochrome P450, family 2, subfamily c, polypeptide 54 0.410
Apoh apolipoprotein H 0.409
Slc4a4 solute carrier family 4 (anion exchanger), member 4 0.405
Ednrb endothelin receptor type B 0.405
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.404
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Fasn fatty acid synthase 0.973
Cyp51 cytochrome P450, family 51 0.857
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.834
Pkm2 pyruvate kinase, muscle 0.829
Abcb11 ATP-binding cassette, subfamily B (MDR/TAP), member 11 0.778
Lss lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.744
Dhcr7 7-dehydrocholesterol reductase 0.717
Acly ATP citrate lyase 0.658
Fdps farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) 0.649
Sc4mol sterol-C4-methyl oxidase-like 0.649
Acat3 acetyl-Coenzyme A acetyltransferase 3 0.628
Fdft1 farnesyl diphosphate farnesyl transferase 1 0.625
Cd36 CD36 molecule (thrombospondin receptor) 0.580
Aqp9 aquaporin 9 0.544
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.511
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.489
Gapdh glyceraldehyde-3-phosphate dehydrogenase 0.417
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.400
Sqle squalene epoxidase 0.386
Cyp2a1 cytochrome P450, family 2, subfamily a, polypeptide 1 0.365
Prlr prolactin receptor 0.347
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.342
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.328
Insig1 insulin induced gene 1 0.325
G6pc glucose-6-phosphatase, catalytic subunit 0.307
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.306
Aldoa aldolase A, fructose-bisphosphate 0.304
Naaladl1 N-acetylated alpha-linked acidic dipeptidase-like 1 0.300
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.296
Gclc glutamate-cysteine ligase, catalytic subunit 0.294
Fads1 fatty acid desaturase 1 0.290
Gpam glycerol-3-phosphate acyltransferase, mitochondrial 0.283
Pnlip pancreatic lipase 0.269
Acot2 acyl-CoA thioesterase 2 0.260
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.260
Idi1 isopentenyl-diphosphate delta isomerase 1 0.252
Grm7 glutamate receptor, metabotropic 7 0.251
Rgs9 regulator of G-protein signaling 9 0.250
Sult1b1 sulfotransferase family, cytosolic, 1B, member 1 0.250
Rnase1 ribonuclease, RNase A family, 1 (pancreatic) 0.250
Pla2g2c phospholipase A2, group IIC 0.249
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.244
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.232
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.231
Cyp4f1 cytochrome P450, family 4, subfamily f, polypeptide 1 0.224
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 0.224
Tpbpa trophoblast specific protein alpha 0.223
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 0.211
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.211
Slc17a1 solute carrier family 17 (sodium phosphate), member 1 0.211
Fads2 fatty acid desaturase 2 0.203
Pdpn podoplanin 0.201
Rup2 urinary protein 2 0.200
Sult1e1 sulfotransferase family 1E, estrogen-preferring, member 1 0.198
LOC293989 cytochrome P450-like 0.198
Tdo2 tryptophan 2,3-dioxygenase 0.197
Olr1280 olfactory receptor 1280 0.196
Ctsj cathepsin J 0.193
Acsm3 acyl-CoA synthetase medium-chain family member 3 0.192
Kynu kynureninase (L-kynurenine hydrolase) 0.192
Agxt2 alanine-glyoxylate aminotransferase 2 0.191
Pparg peroxisome proliferator-activated receptor gamma 0.191
Cbs cystathionine beta synthase 0.186
Gpd1 glycerol-3-phosphate dehydrogenase 1 (soluble) 0.184
Tspo translocator protein 0.184
Scd1 stearoyl-Coenzyme A desaturase 1 0.182
Foxa1 forkhead box A1 0.181
Amy2 amylase 2, pancreatic 0.180
Acadvl acyl-Coenzyme A dehydrogenase, very long chain 0.178
Slc22a25 solute carrier family 22, member 25 0.178
Afm afamin 0.177
Psp parotid secretory protein 0.176
Tat tyrosine aminotransferase 0.176
Acaa2 acetyl-Coenzyme A acyltransferase 2 0.166
Nsdhl NAD(P) dependent steroid dehydrogenase-like 0.166
Grb7 growth factor receptor bound protein 7 0.162
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.161
Aqp8 aquaporin 8 0.160
Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 0.160
Cnga1 cyclic nucleotide gated channel alpha 1 0.159
Aqp7 aquaporin 7 0.157
Acss2 acyl-CoA synthetase short-chain family member 2 0.157
Fabp1 fatty acid binding protein 1, liver 0.156
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.155
Sult1c2 sulfotransferase family, cytosolic, 1C, member 2 0.153
Acaa1a acetyl-Coenzyme A acyltransferase 1A 0.152
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.152
Ech1 enoyl coenzyme A hydratase 1, peroxisomal 0.151
Impg2 interphotoreceptor matrix proteoglycan 2 0.150
Fap fibroblast activation protein, alpha 0.149
Psmd5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 0.148
Tm7sf2 transmembrane 7 superfamily member 2 0.148
Mvk mevalonate kinase 0.147
Efnb1 ephrin B1 0.146
Scd stearoyl-CoA desaturase (delta-9-desaturase) 0.144
Nfe2l2 nuclear factor, erythroid derived 2, like 2 0.144
Dhfr dihydrofolate reductase 0.144
Cela1 chymotrypsin-like elastase family, member 1 0.144
Dbp D site of albumin promoter (albumin D-box) binding protein 0.143
Aadat aminoadipate aminotransferase 0.141
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ERG2 Erg2p 0.989
ERG6 Erg6p 0.985
ERG25 Erg25p 0.980
ERG5 Erg5p 0.963
ERG3 Erg3p 0.960
ERG11 Erg11p 0.953
SNZ2 Snz2p 0.952
SAC1 Sac1p 0.942
ARO8 Aro8p 0.936
ERG26 Erg26p 0.929
ACS2 Acs2p 0.917
ERG27 Erg27p 0.917
MVD1 Mvd1p 0.914
ARO1 Aro1p 0.898
ARO2 Aro2p 0.866
THR4 Thr4p 0.863
PHO86 Pho86p 0.855
SAM1 Sam1p 0.850
FAS1 Fas1p 0.849
BAT1 Bat1p 0.848
ASN1 Asn1p 0.846
ERG7 Erg7p 0.842
ERG28 Erg28p 0.841
ACC1 Acc1p 0.839
ARG5,6 Arg5,6p 0.825
TRP3 Trp3p 0.820
SER1 Ser1p 0.810
OPI3 Opi3p 0.809
MCK1 Mck1p 0.801
THR1 Thr1p 0.796
MET6 Met6p 0.777
SOR1 Sor1p 0.772
LEU9 Leu9p 0.767
ERG4 Erg4p 0.758
GDH1 Gdh1p 0.757
ERG24 Erg24p 0.755
ERG8 Erg8p 0.749
PRO2 Pro2p 0.747
MET13 Met13p 0.746
MAE1 Mae1p 0.731
LEU1 Leu1p 0.730
TRP2 Trp2p 0.723
ARG1 Arg1p 0.694
BIO3 Bio3p 0.682
ERG1 Erg1p 0.679
LYS1 Lys1p 0.671
TRP5 Trp5p 0.665
CPA2 Cpa2p 0.665
SNO3 Sno3p 0.639
HIS4 His4p 0.638
UPS2 Ups2p 0.637
ERG9 Erg9p 0.629
ARG4 Arg4p 0.627
SNO2 Sno2p 0.619
ADE3 Ade3p 0.619
CTI6 Cti6p 0.617
SNZ3 Snz3p 0.616
SSM4 Ssm4p 0.604
BDH1 Bdh1p 0.602
ERG12 Erg12p 0.601
GGC1 Ggc1p 0.596
KRS1 Krs1p 0.595
TPS1 Tps1p 0.590
ZWF1 Zwf1p 0.587
IDH2 Idh2p 0.583
HOM2 Hom2p 0.582
HOM3 Hom3p 0.580
MET14 Met14p 0.557
ERG13 Erg13p 0.557
ARG2 Arg2p 0.546
MCT1 Mct1p 0.538
EHT1 Eht1p 0.536
SER3 Ser3p 0.527
VPS75 Vps75p 0.524
ILV1 Ilv1p 0.518
MET3 Met3p 0.513
PHO80 Pho80p 0.504
TKL1 Tkl1p 0.496
LYS2 Lys2p 0.496
CHO2 Cho2p 0.492
UBP15 Ubp15p 0.487
LYS21 Lys21p 0.482
HOR2 Hor2p 0.473
COQ3 Coq3p 0.461
TRM5 Trm5p 0.461
SNZ1 Snz1p 0.457
ADE4 Ade4p 0.452
ALG5 Alg5p 0.452
RPN4 Rpn4p 0.448
MET22 Met22p 0.446
ALD5 Ald5p 0.444
ILV6 Ilv6p 0.442
OAF3 Oaf3p 0.436
IDP1 Idp1p 0.434
MCM1 Mcm1p 0.434
SUL2 Sul2p 0.431
IDH1 Idh1p 0.431
ILV2 Ilv2p 0.426
PHO4 Pho4p 0.422
SAM2 Sam2p 0.420