The network for 'response to stress' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

Homo sapiens
Name Description Probability Func Analog Organism
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
pea3 ETS-domain transcription factor pea3 0.979
bmp2b bone morphogenetic protein 2b 0.913
cdh1 cadherin 1, epithelial 0.911
pitx3 paired-like homeodomain transcription factor 3 0.911
osr1 odd-skipped related 1 (Drosophila) 0.897
shha sonic hedgehog a 0.896
lamc1 laminin, gamma 1 0.889
tal1 T-cell acute lymphocytic leukemia 1 0.885
igf1ra insulin-like growth factor 1a receptor 0.880
apoeb apolipoprotein Eb 0.880
fgf3 fibroblast growth factor 3 0.874
gro1 groucho 1 0.871
nkx3.2 NK3 homeobox 2 0.856
cyp19a1b cytochrome P450, family 19, subfamily A, polypeptide 1b 0.851
hspa5 heat shock protein 5 0.845
gata5 GATA-binding protein 5 0.822
gsc goosecoid 0.803
th tyrosine hydroxylase 0.761
gli1 GLI-Kruppel family member 1 0.760
igfbp1a insulin-like growth factor binding protein 1a 0.752
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.739
hmgb2b high-mobility group box 2b 0.729
cx43 connexin 43 0.728
fgfr1a fibroblast growth factor receptor 1a 0.725
otpa orthopedia homolog a 0.724
col8a1a collagen, type VIII, alpha 1a 0.701
vasp vasodilator-stimulated phosphoprotein 0.700
tagln2 transgelin 2 0.697
gpia glucose phosphate isomerase a 0.696
evx1 even-skipped homeobox 1 0.681
twist3 twist3 0.680
brd2a bromodomain-containing 2a 0.671
nfkbiab nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b 0.670
notch3 notch homolog 3 0.669
mycbp2 MYC binding protein 2 0.666
wls wntless homolog (Drosophila) 0.666
sox32 SRY-box containing gene 32 0.665
ef1a elongation factor 1-alpha 0.657
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.640
pax7a paired box gene 7a 0.639
vasa vasa homolog 0.639
ddb2 damage-specific DNA binding protein 2 0.637
rhoab ras homolog gene family, member Ab 0.636
kita kit receptor a 0.634
cav1 caveolin 1 0.631
robo3 roundabout homolog 3 0.623
ca8 carbonic anhydrase VIII 0.614
hsp90b1 heat shock protein 90, beta (grp94), member 1 0.605
smad1 MAD homolog 1 (Drosophila) 0.598
ctsl1a cathepsin L, 1 a 0.594
mstnb myostatin b 0.594
hmga1a high mobility group AT-hook 1a 0.586
sox19a SRY-box containing gene 19a 0.578
dbx1a developing brain homeobox 1a 0.577
alcamb activated leukocyte cell adhesion molecule b 0.565
junb jun B proto-oncogene 0.561
tlr21 toll-like receptor 21 0.561
wnt2 wingless-type MMTV integration site family member 2 0.555
spry4 sprouty (Drosophila) homolog 4 0.552
sh3gl1b SH3-domain GRB2-like 1b 0.551
fabp7a fatty acid binding protein 7, brain, a 0.537
runx1 runt-related transcription factor 1 0.535
sat1a spermidine/spermine N1-acetyltransferase 1a 0.533
appa amyloid beta (A4) precursor protein a 0.531
epas1b endothelial PAS domain protein 1b 0.525
wnt11r wingless-type MMTV integration site family, member 11, related 0.523
ccnd1 cyclin D1 0.513
mmp9 matrix metalloproteinase 9 0.511
socs1 suppressor of cytokine signaling 1 0.511
bmp4 bone morphogenetic protein 4 0.509
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.509
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.503
tbx18 T-box 18 0.499
igf1 insulin-like growth factor 1 0.493
pycard PYD and CARD domain containing 0.487
nasp nuclear autoantigenic sperm protein (histone-binding) 0.483
dusp6 dual specificity phosphatase 6 0.483
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.478
scrib scribbled homolog (Drosophila) 0.477
erbb3b v-erb-b2 erythroblastic leukemia viral oncogene homolog 3b 0.475
nod1 nucleotide-binding oligomerization domain containing 1 0.474
cx39.9 connexin 39.9 0.471
cry3 cryptochrome 3 0.471
adra2db adrenergic, alpha-2D-, receptor b 0.471
id1 inhibitor of DNA binding 1 0.470
vcp valosin containing protein 0.467
fzd5 frizzled homolog 5 0.465
fzd7a frizzled homolog 7a 0.460
lhx8a LIM homeobox 8a 0.459
junbl jun B proto-oncogene, like 0.458
il1b interleukin 1, beta and interleukin 1, beta 0.458
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.456
atoh1b atonal homolog 1b 0.455
neurog3 neurogenin 3 0.454
msh6 mutS homolog 6 (E. coli) 0.453
igf1rb insulin-like growth factor 1b receptor 0.452
bmper BMP binding endothelial regulator 0.451
spry2 sprouty homolog 2 0.451
foxd3 forkhead box D3 0.451
rasl11b RAS-like, family 11, member B 0.450
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism