The network for 'positive regulation of defense response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of defense response

Any process that activates or increases the frequency, rate or extent of a defense response.

Homo sapiens
Name Description Probability Func Analog Organism
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 1.000
BIRC3 baculoviral IAP repeat containing 3 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.999
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.999
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.997
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.997
CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) 0.997
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.997
IRAK1 interleukin-1 receptor-associated kinase 1 0.993
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.992
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.991
MYD88 myeloid differentiation primary response gene (88) 0.990
TRAF6 TNF receptor-associated factor 6 0.989
TRAF1 TNF receptor-associated factor 1 0.984
MAPK14 mitogen-activated protein kinase 14 0.984
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.984
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.981
RIPK2 receptor-interacting serine-threonine kinase 2 0.980
IRAK2 interleukin-1 receptor-associated kinase 2 0.970
S100B S100 calcium binding protein B 0.968
ESR1 estrogen receptor 1 0.958
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.956
IL8 interleukin 8 0.938
HLA-B major histocompatibility complex, class I, B 0.937
B2M beta-2-microglobulin 0.936
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.935
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.905
BIRC2 baculoviral IAP repeat containing 2 0.900
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.898
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.883
PLAU plasminogen activator, urokinase 0.880
CD84 CD84 molecule 0.862
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.823
TRAF2 TNF receptor-associated factor 2 0.821
TLR4 toll-like receptor 4 0.815
TLR2 toll-like receptor 2 0.815
S100A6 S100 calcium binding protein A6 0.803
HLA-G major histocompatibility complex, class I, G 0.793
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.789
PML promyelocytic leukemia 0.785
IRF7 interferon regulatory factor 7 0.778
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.745
HLA-C major histocompatibility complex, class I, C 0.744
S100A9 S100 calcium binding protein A9 0.723
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.721
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.718
FGF1 fibroblast growth factor 1 (acidic) 0.708
S100A8 S100 calcium binding protein A8 0.705
TRIM22 tripartite motif containing 22 0.705
ICAM1 intercellular adhesion molecule 1 0.703
IFIH1 interferon induced with helicase C domain 1 0.699
NLRC4 NLR family, CARD domain containing 4 0.696
PLAUR plasminogen activator, urokinase receptor 0.679
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.671
STAT1 signal transducer and activator of transcription 1, 91kDa 0.638
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.632
DUSP1 dual specificity phosphatase 1 0.623
IFI44 interferon-induced protein 44 0.600
ANXA1 annexin A1 0.598
CXCL2 chemokine (C-X-C motif) ligand 2 0.592
SP100 SP100 nuclear antigen 0.573
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.545
INPP5D inositol polyphosphate-5-phosphatase, 145kDa 0.529
SAMD9 sterile alpha motif domain containing 9 0.524
HLA-A major histocompatibility complex, class I, A 0.521
S100A16 S100 calcium binding protein A16 0.519
CCR1 chemokine (C-C motif) receptor 1 0.516
CD14 CD14 molecule 0.511
S100A1 S100 calcium binding protein A1 0.510
FAS Fas (TNF receptor superfamily, member 6) 0.487
TRAF3 TNF receptor-associated factor 3 0.486
IFI16 interferon, gamma-inducible protein 16 0.485
HLA-E major histocompatibility complex, class I, E 0.483
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.474
SLAMF1 signaling lymphocytic activation molecule family member 1 0.472
S100A14 S100 calcium binding protein A14 0.468
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.466
LRRK2 leucine-rich repeat kinase 2 0.456
CYLD cylindromatosis (turban tumor syndrome) 0.455
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.455
MET met proto-oncogene (hepatocyte growth factor receptor) 0.432
BCL3 B-cell CLL/lymphoma 3 0.425
CXCL3 chemokine (C-X-C motif) ligand 3 0.423
TNF tumor necrosis factor 0.416
CREBBP CREB binding protein 0.410
PVRL4 poliovirus receptor-related 4 0.405
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.397
XIAP X-linked inhibitor of apoptosis 0.391
MAPK1 mitogen-activated protein kinase 1 0.381
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.379
MAP3K7 mitogen-activated protein kinase kinase kinase 7 0.377
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.359
TAB2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.358
SRGN serglycin 0.356
TLR1 toll-like receptor 1 0.348
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.328
HLA-F major histocompatibility complex, class I, F 0.321
PELI3 pellino homolog 3 (Drosophila) 0.320
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.312
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
F09A5.4 Protein F09A5.4 0.038
unc-94 Protein UNC-94 0.029
sek-1 Protein SEK-1 0.028
C31E10.5 Protein C31E10.5 0.026
F21A10.2 Protein F21A10.2 0.021
glh-1 Protein GLH-1 0.020
C52E12.4 Protein C52E12.4 0.019
unc-43 Protein UNC-43 0.018
lea-1 Protein LEA-1 0.017
drh-1 Protein DRH-1 0.017
zoo-1 Protein ZOO-1 0.016
K06A5.1 Protein K06A5.1 0.016
T01H3.2 Protein T01H3.2 0.015
ehbp-1 Protein EHBP-1 0.014
unc-32 Protein UNC-32 0.014
acs-17 Protein ACS-17 0.013
par-5 Protein PAR-5 0.013
vps-11 Protein VPS-11 0.012
ZK792.5 Protein ZK792.5 0.011
EEED8.16 Protein EEED8.16 0.011
nhr-71 Protein NHR-71 0.011
F28C6.2 Protein F28C6.2 0.010
F41C3.8 Protein F41C3.8 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
nod1 nucleotide-binding oligomerization domain containing 1 0.537
il8 interleukin 8 0.285
stc1l stanniocalcin 1, like 0.283
pdcd2 programmed cell death 2 0.258
cyp3a65 cytochrome P450, family 3, subfamily A, polypeptide 65 0.218
LOC557072 caspase recruitment domain-containing protein 11-like 0.170
rel v-rel reticuloendotheliosis viral oncogene homolog 0.165
tlr9 toll-like receptor 9 0.162
il1b interleukin 1, beta and interleukin 1, beta 0.145
vasa vasa homolog 0.139
defbl3 defensin, beta-like 3 0.133
pea3 ETS-domain transcription factor pea3 0.112
fgfr3 fibroblast growth factor receptor 3 0.103
epas1b endothelial PAS domain protein 1b 0.099
tnfb tumor necrosis factor b (TNF superfamily, member 2) 0.096
ripk2 receptor-interacting serine-threonine kinase 2 0.085
nfkbiaa nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a 0.065
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.063
copa coatomer protein complex, subunit alpha 0.057
f2rl1.2 coagulation factor II (thrombin) receptor-like 1.2 0.057
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.054
fzd2 frizzled homolog 2 0.052
LOC100000934 hypothetical protein LOC100000934 0.052
tlr18 toll-like receptor 18 0.051
spi1l spleen focus forming virus (SFFV) proviral integration oncogene spi1 like 0.051
csf3r colony stimulating factor 3 receptor (granulocyte) 0.048
nanos3 nanos homolog 3 0.044
zgc:56136 zgc:56136 0.041
shbg sex hormone binding globulin 0.036
pth1a parathyroid hormone 1a 0.034
ip6k2 inositol hexaphosphate kinase 2 0.034
itln1 intelectin 1 0.034
ptger2a prostaglandin E receptor 2a (subtype EP2) 0.033
mmp9 matrix metalloproteinase 9 0.033
fxr2 fragile X mental retardation, autosomal homolog 2 0.033
otul OTU like protein 0.031
fadd Fas (tnfrsf6)-associated via death domain 0.031
ptgs1 prostaglandin-endoperoxide synthase 1 0.030
cdh23 cadherin-like 23 0.030
sgpl1 sphingosine-1-phosphate lyase 1 0.030
caspa caspase a 0.030
phrf1 PHD and ring finger domains 1 0.029
gcm2 glial cells missing homolog 2 (Drosophila) 0.029
bhlhe40 basic helix-loop-helix family, member e40 0.027
cd40lg CD40 ligand 0.027
ef1a elongation factor 1-alpha 0.026
stat1b signal transducer and activator of transcription 1b 0.025
yes1 v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 0.025
ifng1-2 interferon, gamma 1-2 0.024
sh3gl1b SH3-domain GRB2-like 1b 0.024
slco1d1 solute carrier organic anion transporter family, member 1D1 0.024
fn1b fibronectin 1b 0.023
hspb6 heat shock protein, alpha-crystallin-related, b6 0.021
ighz immunoglobulin heavy constant zeta 0.021
rhogb ras homolog gene family, member Gb 0.021
tlr21 toll-like receptor 21 0.020
dnd dead end 0.020
si:dkey-8l13.4 si:dkey-8l13.4 0.020
tlr4bb toll-like receptor 4b, duplicate b 0.019
LOC100150090 sphingosine kinase 2-like 0.018
lpp LIM domain containing preferred translocation partner in lipoma 0.018
copg2 coatomer protein complex, subunit gamma 2 0.018
naa15b N(alpha)-acetyltransferase 15, NatA auxiliary subunit b 0.018
clic2 chloride intracellular channel 2 0.017
fbln4 fibulin 4 0.017
sb:cb134 sb:cb134 0.017
si:ch211-195h23.3 si:ch211-195h23.3 0.016
fabp7b fatty acid binding protein 7, brain, b 0.016
polb polymerase (DNA directed), beta 0.016
meis1 myeloid ecotropic viral integration 1 0.016
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.016
runx2a runt-related transcription factor 2a 0.016
grifin galectin related inter-fiber protein 0.016
LOC567678 avidin-like 0.015
ecscr endothelial cell-specific chemotaxis regulator 0.015
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.015
gsk3b glycogen synthase kinase 3 beta 0.014
pdgfaa platelet-derived growth factor alpha a 0.014
fes feline sarcoma oncogene 0.014
arrb2b arrestin, beta 2b 0.014
paqr7b progestin and adipoQ receptor family member VII, b 0.014
tlr20a toll-like receptor 20a 0.014
yth2 YTH domain family 2 0.014
kpna3 karyopherin (importin) alpha 3 0.014
unc5c unc-5 homolog C (C. elegans) 0.014
plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 0.014
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.014
ccr6a chemokine (C-C motif) receptor 6a 0.013
pcsk9 proprotein convertase subtilisin/kexin type 9 0.013
atoh1b atonal homolog 1b 0.013
tirap toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.013
mapk8b mitogen-activated protein kinase 8b 0.013
bmp7b bone morphogenetic protein 7b 0.013
cd247l CD247 antigen like 0.013
ptgs2a prostaglandin-endoperoxide synthase 2a 0.013
hcrt hypocretin (orexin) neuropeptide precursor 0.013
sb:cb429 sb:cb429 0.013
im:7141132 im:7141132 0.013
keap1a kelch-like ECH-associated protein 1a 0.013
hdr hematopoietic death receptor 0.013
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
AttA Attacin-A 0.983
Rel Relish 0.975
DptB Diptericin B 0.956
Spn27A Serpin 27A 0.768
PGRP-LC Peptidoglycan recognition protein LC 0.738
PGRP-SD CG7496 gene product from transcript CG7496-RA 0.713
Mtk Metchnikowin 0.569
PGRP-SA Peptidoglycan recognition protein SA 0.552
fon fondue 0.521
SPE Spatzle-Processing Enzyme 0.490
CG6361 CG6361 gene product from transcript CG6361-RA 0.480
CG15065 CG15065 gene product from transcript CG15065-RA 0.426
CG13422 CG13422 gene product from transcript CG13422-RA 0.386
Spn1 Serine protease inhibitor 1 0.366
spz spatzle 0.351
Sp7 Serine protease 7 0.348
imd immune deficiency 0.333
Dredd Death related ced-3/Nedd2-like protein 0.312
Atg1 Autophagy-specific gene 1 0.297
Spn28D Serpin 28D 0.276
ird5 immune response deficient 5 0.274
BG4 CG12297 gene product from transcript CG12297-RA 0.262
Irc Immune-regulated catalase 0.250
CG5791 CG5791 gene product from transcript CG5791-RA 0.243
grass Gram-positive Specific Serine protease 0.232
pan pangolin 0.226
CG32185 CG32185 gene product from transcript CG32185-RA 0.208
Tl Toll 0.204
Mekk1 CG7717 gene product from transcript CG7717-RB 0.193
Tab2 TAK1-associated binding protein 2 0.189
CecC Cecropin C 0.189
cact cactus 0.180
Mpk2 CG5475 gene product from transcript CG5475-RB 0.174
Timp Tissue inhibitor of metalloproteases 0.171
rev7 CG2948 gene product from transcript CG2948-RA 0.162
CG18666 CG18666 gene product from transcript CG18666-RA 0.154
CG15917 CG15917 gene product from transcript CG15917-RA 0.150
CG15067 CG15067 gene product from transcript CG15067-RA 0.146
nec necrotic 0.145
Dpt Diptericin 0.141
key kenny 0.139
Glt Glutactin 0.138
modSP modular serine protease 0.129
IM18 Immune induced molecule 18 0.127
Dro Drosocin 0.126
Drs Drosomycin 0.126
Toll-6 CG7250 gene product from transcript CG7250-RA 0.126
GNBP3 Gram-negative bacteria binding protein 3 0.122
rpr reaper 0.120
Nrx-IV Neurexin IV 0.118
Pvr PDGF- and VEGF-receptor related 0.117
IM1 Immune induced molecule 1 0.117
PGRP-SC1a CG14746 gene product from transcript CG14746-RA 0.112
Toll-7 CG8595 gene product from transcript CG8595-RA 0.110
IM10 Immune induced molecule 10 0.107
IM4 Immune induced molecule 4 0.102
piwi CG6122 gene product from transcript CG6122-RA 0.101
pzg putzig 0.099
Duox Dual oxidase 0.098
PGRP-SB1 CG9681 gene product from transcript CG9681-RA 0.091
Stam Signal transducing adaptor molecule 0.090
CG16718 CG16718 gene product from transcript CG16718-RA 0.090
bnl branchless 0.089
krz kurtz 0.088
PGRP-SC1b CG8577 gene product from transcript CG8577-RA 0.088
CalpA Calpain-A 0.088
CG10650 CG10650 gene product from transcript CG10650-RA 0.088
IM23 Immune induced molecule 23 0.087
Rac2 CG8556 gene product from transcript CG8556-RA 0.087
NijA Ninjurin A 0.086
Pi3K68D Phosphotidylinositol 3 kinase 68D 0.085
MP1 Melanization Protease 1 0.085
eater CG6124 gene product from transcript CG6124-RB 0.084
Pp1-87B Protein phosphatase 1 at 87B 0.082
Myo31DF Myosin 31DF 0.080
Mcr Macroglobulin complement-related 0.080
ird1 immune response deficient 1 0.078
p38b CG7393 gene product from transcript CG7393-RA 0.077
whd withered 0.076
JIL-1 CG6297 gene product from transcript CG6297-RA 0.074
Cat Catalase 0.071
CG5778 CG5778 gene product from transcript CG5778-RB 0.071
wun wunen 0.070
Hsf Heat shock factor 0.069
dap dacapo 0.069
CG16836 CG16836 gene product from transcript CG16836-RA 0.068
Spn88Eb Serpin 88Eb 0.068
pirk poor Imd response upon knock-in 0.068
pie pineapple eye 0.067
AttC Attacin-C 0.066
mael maelstrom 0.065
CG9631 CG9631 gene product from transcript CG9631-RA 0.065
Traf4 TNF-receptor-associated factor 4 0.063
Myd88 CG2078 gene product from transcript CG2078-RA 0.063
upd2 unpaired 2 0.063
CG18067 CG18067 gene product from transcript CG18067-RA 0.063
GNBP1 Gram-negative bacteria binding protein 1 0.060
gho ghost 0.059
Hs6st Heparan sulfate 6-O-sulfotransferase 0.058
nxf2 nuclear RNA export factor 2 0.057
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Tnf tumor necrosis factor 1.000
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.999
Icos inducible T-cell co-stimulator 0.999
Cd40 CD40 antigen 0.999
Lyz2 lysozyme 2 0.998
Stat3 signal transducer and activator of transcription 3 0.998
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.996
Tlr4 toll-like receptor 4 0.995
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.995
Myd88 myeloid differentiation primary response gene 88 0.991
Casp1 caspase 1 0.991
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.989
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.985
Ptgs2 prostaglandin-endoperoxide synthase 2 0.983
Fas Fas (TNF receptor superfamily member 6) 0.982
Apoe apolipoprotein E 0.979
Ccl2 chemokine (C-C motif) ligand 2 0.974
Ifng interferon gamma 0.972
Il1r1 interleukin 1 receptor, type I 0.972
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.968
Il6 interleukin 6 0.966
Traf6 TNF receptor-associated factor 6 0.954
Selp selectin, platelet 0.953
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.952
Il18rap interleukin 18 receptor accessory protein 0.948
Ccr1 chemokine (C-C motif) receptor 1 0.948
Klra9 killer cell lectin-like receptor subfamily A, member 9 0.947
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.943
Il1b interleukin 1 beta 0.935
Ptprc protein tyrosine phosphatase, receptor type, C 0.931
Ccr2 chemokine (C-C motif) receptor 2 0.926
Traf3ip2 TRAF3 interacting protein 2 0.921
Gzmk granzyme K 0.912
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.904
Clec4d C-type lectin domain family 4, member d 0.903
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.903
Fcgr2b Fc receptor, IgG, low affinity IIb 0.894
Fasl Fas ligand (TNF superfamily, member 6) 0.889
Ccl4 chemokine (C-C motif) ligand 4 0.885
Ccl3 chemokine (C-C motif) ligand 3 0.884
Il1rn interleukin 1 receptor antagonist 0.882
Aoah acyloxyacyl hydrolase 0.879
Il1rl1 interleukin 1 receptor-like 1 0.874
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.867
Axl AXL receptor tyrosine kinase 0.866
Il2 interleukin 2 0.863
Slamf1 signaling lymphocytic activation molecule family member 1 0.858
Cxcl2 chemokine (C-X-C motif) ligand 2 0.854
Clec4n C-type lectin domain family 4, member n 0.835
Cd28 CD28 antigen 0.821
Cd180 CD180 antigen 0.821
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.820
Ncr1 natural cytotoxicity triggering receptor 1 0.818
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.815
Irg1 immunoresponsive gene 1 0.811
Cd14 CD14 antigen 0.801
Tlr2 toll-like receptor 2 0.795
Ubd ubiquitin D 0.791
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide 0.785
Pyhin1 pyrin and HIN domain family, member 1 0.785
Nlrp3 NLR family, pyrin domain containing 3 0.775
Ccr6 chemokine (C-C motif) receptor 6 0.772
Batf2 basic leucine zipper transcription factor, ATF-like 2 0.771
Mefv Mediterranean fever 0.766
Nos2 nitric oxide synthase 2, inducible 0.766
Mavs mitochondrial antiviral signaling protein 0.763
Gzmb granzyme B 0.762
Cd80 CD80 antigen 0.760
Irf7 interferon regulatory factor 7 0.759
Birc3 baculoviral IAP repeat-containing 3 0.754
Fpr2 formyl peptide receptor 2 0.729
Tcra T-cell receptor alpha chain 0.721
Ngp neutrophilic granule protein 0.718
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.713
Il7r interleukin 7 receptor 0.708
Rel reticuloendotheliosis oncogene 0.706
Cxcl9 chemokine (C-X-C motif) ligand 9 0.704
H2-K1 histocompatibility 2, K1, K region 0.703
B2m beta-2 microglobulin 0.702
Gbp2 guanylate binding protein 2 0.701
Clec4e C-type lectin domain family 4, member e 0.697
Il4 interleukin 4 0.695
Il2rg interleukin 2 receptor, gamma chain 0.690
Il18r1 interleukin 18 receptor 1 0.688
Ccr3 chemokine (C-C motif) receptor 3 0.681
Icam1 intercellular adhesion molecule 1 0.669
Cd44 CD44 antigen 0.664
Cxcl10 chemokine (C-X-C motif) ligand 10 0.663
Slfn1 schlafen 1 0.663
Mmp8 matrix metallopeptidase 8 0.659
Il4ra interleukin 4 receptor, alpha 0.658
Clec7a C-type lectin domain family 7, member a 0.658
Ikbkg inhibitor of kappaB kinase gamma 0.656
C3ar1 complement component 3a receptor 1 0.656
Trim21 tripartite motif-containing 21 0.649
Gzma granzyme A 0.644
Mmp12 matrix metallopeptidase 12 0.642
S100a8 S100 calcium binding protein A8 (calgranulin A) 0.640
Esr1 estrogen receptor 1 (alpha) 0.639
Xcl1 chemokine (C motif) ligand 1 0.638
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
S100a9 S100 calcium binding protein A9 0.436
Il1b interleukin 1 beta 0.300
Gzmk granzyme K 0.293
Cd14 CD14 molecule 0.287
S100a8 S100 calcium binding protein A8 0.278
Gzmb granzyme B 0.238
Met met proto-oncogene 0.186
Ccr1 chemokine (C-C motif) receptor 1 0.142
Ccl3 chemokine (C-C motif) ligand 3 0.142
Igsf6 immunoglobulin superfamily, member 6 0.141
Ptafr platelet-activating factor receptor 0.114
Lilrb4 leukocyte immunoglobulin-like receptor, subfamily B, member 4 0.113
LOC100363783 rCG53773-like 0.113
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.103
Calcrl calcitonin receptor-like 0.095
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.088
Apol3 apolipoprotein L, 3 0.084
Il4 interleukin 4 0.083
Csf1 colony stimulating factor 1 (macrophage) 0.074
Ncr1 natural cytotoxicity triggering receptor 1 0.073
Dbp D site of albumin promoter (albumin D-box) binding protein 0.072
Gstm3 glutathione S-transferase mu 3 0.072
Stat3 signal transducer and activator of transcription 3 0.067
Il1a interleukin 1 alpha 0.063
Cd38 CD38 molecule 0.062
Il4ra interleukin 4 receptor, alpha 0.062
Cd8a CD8a molecule 0.061
Il1r2 interleukin 1 receptor, type II 0.060
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.059
Il6 interleukin 6 0.057
Tlr2 toll-like receptor 2 0.055
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 0.055
Pecam1 platelet/endothelial cell adhesion molecule 1 0.055
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.054
Crhbp corticotropin releasing hormone binding protein 0.053
Cd3g CD3 molecule, gamma 0.053
Sst somatostatin 0.053
Cd44 Cd44 molecule 0.051
Ccl4 chemokine (C-C motif) ligand 4 0.051
Htr6 5-hydroxytryptamine (serotonin) receptor 6 0.050
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.049
C5ar1 complement component 5a receptor 1 0.049
Htr2a 5-hydroxytryptamine (serotonin) receptor 2A 0.049
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.048
Il1r1 interleukin 1 receptor, type I 0.048
Il1rn interleukin 1 receptor antagonist 0.048
RGD1559588 similar to cell surface receptor FDFACT 0.046
Anpep alanyl (membrane) aminopeptidase 0.046
Cxcl2 chemokine (C-X-C motif) ligand 2 0.046
Lig3 ligase III, DNA, ATP-dependent 0.045
Tgif1 TGFB-induced factor homeobox 1 0.044
Prf1 perforin 1 (pore forming protein) 0.043
Ifng interferon gamma 0.043
Tcf4 transcription factor 4 0.042
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.042
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.042
Aqp4 aquaporin 4 0.042
Pla2g4a phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.040
Des desmin 0.040
Cd86 CD86 molecule 0.040
Gp5 glycoprotein V (platelet) 0.040
Jak1 Janus kinase 1 0.039
Cdh17 cadherin 17 0.039
Ccr2 chemokine (C-C motif) receptor 2 0.039
Ccl7 chemokine (C-C motif) ligand 7 0.038
Strn striatin, calmodulin binding protein 0.038
Flt1 FMS-related tyrosine kinase 1 0.038
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.038
Nras neuroblastoma ras oncogene 0.038
Plaur plasminogen activator, urokinase receptor 0.038
Sgk2 serum/glucocorticoid regulated kinase 2 0.038
Socs3 suppressor of cytokine signaling 3 0.037
Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 0.037
Notch2 Notch homolog 2 (Drosophila) 0.037
Il2rb interleukin 2 receptor, beta 0.037
Lpl lipoprotein lipase 0.036
Casp12 caspase 12 0.036
Sstr4 somatostatin receptor 4 0.035
Elf1 E74-like factor 1 0.035
Hist1h1d histone cluster 1, H1d 0.035
RT1-Ba RT1 class II, locus Ba 0.035
Ptger2 prostaglandin E receptor 2 (subtype EP2) 0.034
Dnase1 deoxyribonuclease I 0.034
Ccl2 chemokine (C-C motif) ligand 2 0.034
Olfml2a olfactomedin-like 2A 0.034
Tfec transcription factor EC 0.034
Rab32 RAB32, member RAS oncogene family 0.034
Muc4 mucin 4, cell surface associated 0.033
Cmklr1 chemokine-like receptor 1 0.033
Mmp3 matrix metallopeptidase 3 0.032
Agtr1a angiotensin II receptor, type 1a 0.032
Rpl36a ribosomal protein L36a 0.032
Stfa2l3 stefin A2-like 3 0.032
Folr2 folate receptor 2 (fetal) 0.032
Fgr Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.032
Cxcl16 chemokine (C-X-C motif) ligand 16 0.032
Ptgfr prostaglandin F receptor 0.032
Il7r interleukin 7 receptor 0.031
Tacr1 tachykinin receptor 1 0.031
Ednra endothelin receptor type A 0.031
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism