IMP
Process View
The network for 'eosinophil activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
eosinophil activation
The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.996 | |
| TFF1 | trefoil factor 1 | 0.964 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.941 | |
| IL8 | interleukin 8 | 0.894 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.741 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.695 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.686 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.669 | |
| IL1B | interleukin 1, beta | 0.607 | |
| IDE | insulin-degrading enzyme | 0.589 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.586 | |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) | 0.506 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.496 | |
| IL2RB | interleukin 2 receptor, beta | 0.454 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.445 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.429 | |
| IFNG | interferon, gamma | 0.407 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.376 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.370 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.360 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.340 | |
| IL10 | interleukin 10 | 0.330 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.327 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.259 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.241 | |
| FPR3 | formyl peptide receptor 3 | 0.232 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.221 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.193 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.191 | |
| NKG7 | natural killer cell group 7 sequence | 0.190 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.187 | |
| AGFG1 | ArfGAP with FG repeats 1 | 0.173 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.167 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.163 | |
| CAV2 | caveolin 2 | 0.162 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.157 | |
| GNLY | granulysin | 0.156 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.151 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.148 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.148 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.128 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.127 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.114 | |
| TNF | tumor necrosis factor | 0.112 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.109 | |
| INADL | InaD-like (Drosophila) | 0.105 | |
| RGS1 | regulator of G-protein signaling 1 | 0.103 | |
| SELE | selectin E | 0.098 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.098 | |
| PRF1 | perforin 1 (pore forming protein) | 0.097 | |
| IL10RA | interleukin 10 receptor, alpha | 0.095 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.095 | |
| UBD | ubiquitin D | 0.088 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.085 | |
| GPR171 | G protein-coupled receptor 171 | 0.081 | |
| CD83 | CD83 molecule | 0.078 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.077 | |
| CLEC10A | C-type lectin domain family 10, member A | 0.073 | |
| GZMK | granzyme K (granzyme 3; tryptase II) | 0.072 | |
| RUNX3 | runt-related transcription factor 3 | 0.072 | |
| SLAMF7 | SLAM family member 7 | 0.071 | |
| LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.071 | |
| CH25H | cholesterol 25-hydroxylase | 0.067 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.066 | |
| CD80 | CD80 molecule | 0.063 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.062 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.061 | |
| DARC | Duffy blood group, chemokine receptor | 0.057 | |
| HK3 | hexokinase 3 (white cell) | 0.057 | |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.056 | |
| CD48 | CD48 molecule | 0.055 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.054 | |
| CD69 | CD69 molecule | 0.052 | |
| IL32 | interleukin 32 | 0.052 | |
| ARRB1 | arrestin, beta 1 | 0.050 | |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.050 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.049 | |
| IL21R | interleukin 21 receptor | 0.048 | |
| IRF8 | interferon regulatory factor 8 | 0.048 | |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.048 | |
| CD160 | CD160 molecule | 0.045 | |
| CLEC7A | C-type lectin domain family 7, member A | 0.045 | |
| EBI3 | Epstein-Barr virus induced 3 | 0.044 | |
| CCL1 | chemokine (C-C motif) ligand 1 | 0.043 | |
| XCL2 | chemokine (C motif) ligand 2 | 0.042 | |
| C5AR1 | complement component 5a receptor 1 | 0.042 | |
| IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.042 | |
| CTSW | cathepsin W | 0.041 | |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.040 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.040 | |
| IL7R | interleukin 7 receptor | 0.040 | |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | 0.040 | |
| KLRK1 | killer cell lectin-like receptor subfamily K, member 1 | 0.039 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.039 | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.038 | |
| CCL23 | chemokine (C-C motif) ligand 23 | 0.037 | |
| DOK2 | docking protein 2, 56kDa | 0.037 | |
| SLAMF8 | SLAM family member 8 | 0.036 | |
| STAT4 | signal transducer and activator of transcription 4 | 0.036 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Ccl2 | chemokine (C-C motif) ligand 2 | 0.999 | |
| Ccr2 | chemokine (C-C motif) receptor 2 | 0.966 | |
| Ccr5 | chemokine (C-C motif) receptor 5 | 0.956 | |
| Ifng | interferon gamma | 0.950 | |
| Cd44 | CD44 antigen | 0.917 | |
| Klrk1 | killer cell lectin-like receptor subfamily K, member 1 | 0.814 | |
| Cd7 | CD7 antigen | 0.752 | |
| Ccr6 | chemokine (C-C motif) receptor 6 | 0.740 | |
| Cd180 | CD180 antigen | 0.696 | |
| Tnf | tumor necrosis factor | 0.667 | |
| Xcr1 | chemokine (C motif) receptor 1 | 0.634 | |
| Ccr1 | chemokine (C-C motif) receptor 1 | 0.548 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.545 | |
| Ciita | class II transactivator | 0.527 | |
| Blk | B lymphoid kinase | 0.524 | |
| Il10 | interleukin 10 | 0.481 | |
| Itgax | integrin alpha X | 0.470 | |
| Mmp9 | matrix metallopeptidase 9 | 0.461 | |
| P2rx7 | purinergic receptor P2X, ligand-gated ion channel, 7 | 0.436 | |
| Klra5 | killer cell lectin-like receptor, subfamily A, member 5 | 0.436 | |
| Klrd1 | killer cell lectin-like receptor, subfamily D, member 1 | 0.430 | |
| Foxp3 | forkhead box P3 | 0.429 | |
| Tlr4 | toll-like receptor 4 | 0.427 | |
| Il18rap | interleukin 18 receptor accessory protein | 0.397 | |
| Lyz2 | lysozyme 2 | 0.391 | |
| Cxcr3 | chemokine (C-X-C motif) receptor 3 | 0.388 | |
| Map3k14 | mitogen-activated protein kinase kinase kinase 14 | 0.375 | |
| Klrg1 | killer cell lectin-like receptor subfamily G, member 1 | 0.368 | |
| Ccl4 | chemokine (C-C motif) ligand 4 | 0.352 | |
| Prdm1 | PR domain containing 1, with ZNF domain | 0.352 | |
| Fcrla | Fc receptor-like A | 0.351 | |
| Tlr2 | toll-like receptor 2 | 0.346 | |
| Selp | selectin, platelet | 0.339 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.329 | |
| Cxcl13 | chemokine (C-X-C motif) ligand 13 | 0.311 | |
| Klrb1b | killer cell lectin-like receptor subfamily B member 1B | 0.295 | |
| H2-Ob | histocompatibility 2, O region beta locus | 0.293 | |
| Tnfrsf4 | tumor necrosis factor receptor superfamily, member 4 | 0.286 | |
| Il12rb2 | interleukin 12 receptor, beta 2 | 0.278 | |
| Pik3cg | phosphoinositide-3-kinase, catalytic, gamma polypeptide | 0.259 | |
| Icos | inducible T-cell co-stimulator | 0.258 | |
| Sfpi1 | SFFV proviral integration 1 | 0.245 | |
| Fgd3 | FYVE, RhoGEF and PH domain containing 3 | 0.244 | |
| Fcer2a | Fc receptor, IgE, low affinity II, alpha polypeptide | 0.242 | |
| Cx3cr1 | chemokine (C-X3-C) receptor 1 | 0.241 | |
| Cd19 | CD19 antigen | 0.230 | |
| Gzmk | granzyme K | 0.227 | |
| Cd96 | CD96 antigen | 0.223 | |
| Itk | IL2-inducible T-cell kinase | 0.221 | |
| Lta | lymphotoxin A | 0.221 | |
| Fasl | Fas ligand (TNF superfamily, member 6) | 0.220 | |
| Ms4a1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.210 | |
| Tnfsf14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.201 | |
| Spn | sialophorin | 0.201 | |
| Ccl3 | chemokine (C-C motif) ligand 3 | 0.199 | |
| Klrc1 | killer cell lectin-like receptor subfamily C, member 1 | 0.196 | |
| Cd4 | CD4 antigen | 0.196 | |
| Il1r1 | interleukin 1 receptor, type I | 0.195 | |
| Spib | Spi-B transcription factor (Spi-1/PU.1 related) | 0.191 | |
| Cxcr2 | chemokine (C-X-C motif) receptor 2 | 0.187 | |
| Itgal | integrin alpha L | 0.185 | |
| Gzmb | granzyme B | 0.177 | |
| Gpr132 | G protein-coupled receptor 132 | 0.169 | |
| Il27ra | interleukin 27 receptor, alpha | 0.168 | |
| S1pr4 | sphingosine-1-phosphate receptor 4 | 0.167 | |
| Il4 | interleukin 4 | 0.162 | |
| Gcet2 | germinal center expressed transcript 2 | 0.149 | |
| Sell | selectin, lymphocyte | 0.142 | |
| Cd3e | CD3 antigen, epsilon polypeptide | 0.139 | |
| Elf4 | E74-like factor 4 (ets domain transcription factor) | 0.137 | |
| Sh2d2a | SH2 domain protein 2A | 0.129 | |
| Il18r1 | interleukin 18 receptor 1 | 0.128 | |
| Klra9 | killer cell lectin-like receptor subfamily A, member 9 | 0.127 | |
| Bex6 | brain expressed gene 6 | 0.122 | |
| Slamf1 | signaling lymphocytic activation molecule family member 1 | 0.122 | |
| Art2a-ps | ADP-ribosyltransferase 2a, pseudogene | 0.122 | |
| F2rl2 | coagulation factor II (thrombin) receptor-like 2 | 0.121 | |
| Fgr | Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog | 0.120 | |
| Tnfrsf9 | tumor necrosis factor receptor superfamily, member 9 | 0.119 | |
| Rgs14 | regulator of G-protein signaling 14 | 0.115 | |
| Cd6 | CD6 antigen | 0.105 | |
| Ctsw | cathepsin W | 0.104 | |
| Il2rb | interleukin 2 receptor, beta chain | 0.103 | |
| Pou2af1 | POU domain, class 2, associating factor 1 | 0.101 | |
| Ifngr1 | interferon gamma receptor 1 | 0.097 | |
| Ltb | lymphotoxin B | 0.097 | |
| Ccr9 | chemokine (C-C motif) receptor 9 | 0.097 | |
| H2-Oa | histocompatibility 2, O region alpha locus | 0.095 | |
| Tnfsf8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.093 | |
| Ccr1l1 | chemokine (C-C motif) receptor 1-like 1 | 0.092 | |
| Spp1 | secreted phosphoprotein 1 | 0.092 | |
| Ctla4 | cytotoxic T-lymphocyte-associated protein 4 | 0.092 | |
| Elk4 | ELK4, member of ETS oncogene family | 0.092 | |
| Cxcr5 | chemokine (C-X-C motif) receptor 5 | 0.091 | |
| Ccr7 | chemokine (C-C motif) receptor 7 | 0.090 | |
| Csf3r | colony stimulating factor 3 receptor (granulocyte) | 0.089 | |
| Olfr140 | olfactory receptor 140 | 0.088 | |
| Flt3 | FMS-like tyrosine kinase 3 | 0.087 | |
| Cd5 | CD5 antigen | 0.086 | |
| Il7r | interleukin 7 receptor | 0.085 |