The network for 'regulation of chromosome segregation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of chromosome segregation

Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.

Name Description Probability Func Analog Organism
CDC27 cell division cycle 27 homolog (S. cerevisiae) 1.000
BUB1B budding uninhibited by benzimidazoles 1 homolog beta (yeast) 1.000
CDC20 cell division cycle 20 homolog (S. cerevisiae) 1.000
ANAPC4 anaphase promoting complex subunit 4 0.999
CCNB1 cyclin B1 0.996
CCNA2 cyclin A2 0.992
ANAPC7 anaphase promoting complex subunit 7 0.983
BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) 0.975
ANAPC5 anaphase promoting complex subunit 5 0.974
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.959
CCT8 chaperonin containing TCP1, subunit 8 (theta) 0.955
CDC23 cell division cycle 23 homolog (S. cerevisiae) 0.932
CDK2 cyclin-dependent kinase 2 0.859
RB1 retinoblastoma 1 0.850
CCNB2 cyclin B2 0.844
MDC1 mediator of DNA-damage checkpoint 1 0.836
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.802
FBXO5 F-box protein 5 0.797
SMC3 structural maintenance of chromosomes 3 0.776
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.775
AURKB aurora kinase B 0.729
FOXM1 forkhead box M1 0.699
VHL von Hippel-Lindau tumor suppressor 0.639
PRC1 protein regulator of cytokinesis 1 0.635
BRCA1 breast cancer 1, early onset 0.622
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.619
UBE2C ubiquitin-conjugating enzyme E2C 0.594
CDKN3 cyclin-dependent kinase inhibitor 3 0.570
RBL1 retinoblastoma-like 1 (p107) 0.557
SKP2 S-phase kinase-associated protein 2 (p45) 0.554
PLK1 polo-like kinase 1 0.542
MKI67 antigen identified by monoclonal antibody Ki-67 0.525
SMC1A structural maintenance of chromosomes 1A 0.503
ANAPC1 anaphase promoting complex subunit 1 0.487
CKS1B CDC28 protein kinase regulatory subunit 1B 0.486
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme 0.484
ANAPC11 anaphase promoting complex subunit 11 0.448
PTTG1 pituitary tumor-transforming 1 0.447
KIF23 kinesin family member 23 0.440
STAG1 stromal antigen 1 0.416
RAD21 RAD21 homolog (S. pombe) 0.412
BUB1 budding uninhibited by benzimidazoles 1 homolog (yeast) 0.392
KIF11 kinesin family member 11 0.388
NASP nuclear autoantigenic sperm protein (histone-binding) 0.385
SPAG5 sperm associated antigen 5 0.360
CDK1 cyclin-dependent kinase 1 0.346
TRIP13 thyroid hormone receptor interactor 13 0.344
CKS2 CDC28 protein kinase regulatory subunit 2 0.341
CEP55 centrosomal protein 55kDa 0.341
BIRC5 baculoviral IAP repeat containing 5 0.331
NSMCE4A non-SMC element 4 homolog A (S. cerevisiae) 0.316
H2AFX H2A histone family, member X 0.304
NUSAP1 nucleolar and spindle associated protein 1 0.303
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.296
ORC2 origin recognition complex, subunit 2 0.289
KIF18A kinesin family member 18A 0.283
KPNB1 karyopherin (importin) beta 1 0.264
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.261
COPS5 COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) 0.245
WHSC1 Wolf-Hirschhorn syndrome candidate 1 0.240
CENPF centromere protein F, 350/400kDa (mitosin) 0.233
ZWINT ZW10 interactor 0.230
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.219
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 0.215
MELK maternal embryonic leucine zipper kinase 0.214
MOBKL3 MOB1, Mps One Binder kinase activator-like 3 (yeast) 0.214
CDC45 cell division cycle 45 homolog (S. cerevisiae) 0.213
PPP2R5C protein phosphatase 2, regulatory subunit B', gamma 0.205
CHAF1A chromatin assembly factor 1, subunit A (p150) 0.200
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.200
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.198
CDT1 chromatin licensing and DNA replication factor 1 0.193
NEK2 NIMA (never in mitosis gene a)-related kinase 2 0.192
CD44 CD44 molecule (Indian blood group) 0.191
CENPE centromere protein E, 312kDa 0.186
CDC7 cell division cycle 7 homolog (S. cerevisiae) 0.185
APC adenomatous polyposis coli 0.173
EZR ezrin 0.169
E2F1 E2F transcription factor 1 0.169
NDC80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.169
CCDC99 coiled-coil domain containing 99 0.168
SMAD2 SMAD family member 2 0.166
STAG2 stromal antigen 2 0.164
CBX5 chromobox homolog 5 0.158
CHAF1B chromatin assembly factor 1, subunit B (p60) 0.155
TUBGCP3 tubulin, gamma complex associated protein 3 0.153
SMC6 structural maintenance of chromosomes 6 0.152
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.151
FANCI Fanconi anemia, complementation group I 0.144
CDC16 cell division cycle 16 homolog (S. cerevisiae) 0.142
CDCA8 cell division cycle associated 8 0.140
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.138
EHD1 EH-domain containing 1 0.138
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.132
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme 0.129
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.129
TPX2 TPX2, microtubule-associated, homolog (Xenopus laevis) 0.125
TOP2A topoisomerase (DNA) II alpha 170kDa 0.124
CUL4A cullin 4A 0.122
DOT1L DOT1-like, histone H3 methyltransferase (S. cerevisiae) 0.122
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
bub-1 Protein BUB-1 0.284
CELE_C24H12.5 Protein C24H12.5 0.190
rod-1 Protein ROD-1 0.188
zyg-9 Protein ZYG-9 0.181
zif-1 Protein ZIF-1 0.139
cye-1 Protein CYE-1 0.091
glh-4 Protein GLH-4 0.081
hcp-2 Protein HCP-2 0.068
rnr-1 Protein RNR-1 0.057
knl-3 Protein KNL-3 0.056
cyb-2.1 Protein CYB-2.1 0.054
prp-3 Protein PRP-3 0.054
zwl-1 Protein ZWL-1 0.054
axl-1 Protein AXL-1 0.050
trr-1 Protein TRR-1 0.050
imb-2 Protein IMB-2 0.046
ucr-2.3 Protein UCR-2.3 0.044
gck-2 Protein GCK-2 0.043
ZC434.8 Protein ZC434.8 0.041
hcp-1 Protein HCP-1 0.040
CELE_F13E9.1 Protein F13E9.1 0.038
toe-2 Protein TOE-2 0.037
lrr-1 Protein LRR-1 0.034
T28C6.7 Protein T28C6.7 0.034
ttm-4 Protein TTM-4 0.034
cin-4 Protein CIN-4 0.033
B0491.1 Protein B0491.1 0.032
mcm-3 Protein MCM-3 0.032
flh-1 Protein FLH-1 0.031
mcm-5 Protein MCM-5 0.031
mex-1 Protein MEX-1 0.031
klp-18 Protein KLP-18 0.030
cas-2 Protein CAS-2 0.028
T08A11.2 Protein T08A11.2 0.028
F20A1.9 Protein F20A1.9 0.027
smc-3 Protein SMC-3 0.026
ZK507.6 Protein ZK507.6 0.026
mex-3 Protein MEX-3 0.026
him-10 Protein HIM-10 0.026
his-6 Protein HIS-6 0.025
mup-4 Protein MUP-4 0.025
sun-1 Protein SUN-1 0.025
mom-2 Protein MOM-2 0.025
prp-21 Protein PRP-21 0.025
gpr-2 Protein GPR-2 0.024
pop-1 Protein POP-1 0.023
knl-1 Protein KNL-1 0.023
bmk-1 Protein BMK-1 0.023
R11A8.7 Protein R11A8.7 0.023
tpxl-1 Protein TPXL-1 0.023
cyk-1 Protein CYK-1 0.023
R06F6.8 Protein R06F6.8 0.022
aipl-1 Protein AIPL-1 0.022
smc-4 Protein SMC-4 0.022
spd-2 Protein SPD-2 0.021
nhr-6 Protein NHR-6 0.021
F18A1.7 Protein F18A1.7 0.020
his-32 Protein HIS-32 0.020
math-33 Protein MATH-33 0.020
rev-1 Protein REV-1 0.020
clp-2 Protein CLP-2 0.020
Y43E12A.2 Protein Y43E12A.2 0.020
CELE_C36A4.5 Protein C36A4.5 0.019
fem-1 Protein FEM-1 0.019
klp-19 Protein KLP-19 0.019
dcr-1 Protein DCR-1 0.019
mcm-2 Protein MCM-2 0.019
CELE_R06A4.2 Protein R06A4.2 0.019
pri-2 Protein PRI-2 0.019
pgl-3 Protein PGL-3 0.019
mup-2 Protein MUP-2 0.019
gex-2 Protein GEX-2 0.018
secs-1 Protein SECS-1 0.018
puf-7 Protein PUF-7 0.018
gyg-2 Protein GYG-2 0.018
C18F10.7 Protein C18F10.7 0.018
glt-1 Protein GLT-1 0.018
tra-1 Protein TRA-1 0.018
vps-33.2 Protein VPS-33.2 0.018
ifb-2 Protein IFB-2 0.018
klp-16 Protein KLP-16 0.017
Y47D3A.29 Protein Y47D3A.29 0.017
gla-3 Protein GLA-3 0.017
rpn-1 Protein RPN-1 0.017
cul-1 Protein CUL-1 0.017
Y48G1C.7 Protein Y48G1C.7 0.016
capg-2 Protein CAPG-2 0.016
pcn-1 Protein PCN-1 0.016
fzy-1 Protein FZY-1 0.016
let-99 Protein LET-99 0.015
pod-1 Protein POD-1 0.015
lag-1 Protein LAG-1 0.015
C02B10.5 Protein C02B10.5 0.015
npp-3 Protein NPP-3 0.015
ubc-3 Protein UBC-3 0.015
T28D9.4 Protein T28D9.4 0.015
fsn-1 Protein FSN-1 0.015
lmn-1 Protein LMN-1 0.015
ifd-2 Protein IFD-2 0.014
F53B7.3 Protein F53B7.3 0.014
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ccnb1 cyclin B1 0.907
kif23 kinesin family member 23 0.812
ccna2 cyclin A2 0.810
aurkb aurora kinase B 0.784
ccnb2 cyclin B2 0.756
si:ch211-69g19.2 si:ch211-69g19.2 0.681
cdc20 cell division cycle 20 homolog 0.676
cdca8 cell division cycle associated 8 0.481
sass6 spindle assembly 6 homolog (C. elegans) 0.471
si:ch211-244o22.2 si:ch211-244o22.2 0.456
ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.441
wu:fi04f09 wu:fi04f09 0.417
tacc3 transforming, acidic coiled-coil containing protein 3 0.394
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.375
plk1 polo-like kinase 1 (Drosophila) 0.306
cstf1 cleavage stimulation factor, 3' pre-RNA, subunit 1 0.302
nusap1 nucleolar and spindle associated protein 1 0.294
ncapd2 non-SMC condensin I complex, subunit D2 0.293
cep55l centrosomal protein 55 like 0.254
pou5f1 POU domain, class 5, transcription factor 1 0.241
khdrbs1b KH domain containing, RNA binding, signal transduction associated 1b 0.233
pbrm1l polybromo 1, like 0.218
dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.211
aurka aurora kinase A 0.211
nuf2 NUF2, NDC80 kinetochore complex component, homolog 0.209
kif11 kinesin family member 11 0.179
capn2b calpain 2, (m/II) large subunit b 0.170
wdhd1 WD repeat and HMG-box DNA binding protein 1 0.169
g2e3 G2/M-phase specific E3 ubiquitin ligase 0.158
sept7b septin 7b 0.156
rrm1 ribonucleotide reductase M1 polypeptide 0.152
usp5 ubiquitin specific protease 5 0.149
sae1 SUMO1 activating enzyme subunit 1 0.145
zgc:153910 zgc:153910 0.142
zgc:110113 zgc:110113 0.137
zgc:174506 zgc:174506 0.127
si:ch211-156j22.4 si:ch211-156j22.4 0.118
zgc:77262 zgc:77262 0.112
LOC100536090 targeting protein for Xklp2-B-like 0.111
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.100
si:ch211-197n10.2 si:ch211-197n10.2 0.097
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.095
zgc:92661 zgc:92661 0.092
pif1 PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae) 0.089
zgc:153369 zgc:153369 0.089
zgc:162965 zgc:162965 0.088
zgc:92607 zgc:92607 0.088
rtkn2 rhotekin 2 0.086
srsf1a serine/arginine-rich splicing factor 1a 0.086
arid4a AT rich interactive domain 4A (RBP1-like) 0.086
dtl denticleless homolog (Drosophila) 0.085
cdc25 cell division cycle 25 homolog 0.081
kif20bb kinesin family member 20Bb 0.080
tmpoa thymopoietin a 0.079
melk maternal embryonic leucine zipper kinase 0.075
hn1l hematological and neurological expressed 1-like 0.071
ck2b casein kinase 2 beta 0.071
smad9 MAD homolog 9 (Drosophila) 0.071
rbpja recombination signal binding protein for immunoglobulin kappa J region a 0.069
slbp stem-loop binding protein 0.069
lrmp lymphoid-restricted membrane protein 0.068
pik3r4 phosphoinositide-3-kinase, regulatory subunit 4 0.068
ncapg non-SMC condensin I complex, subunit G 0.068
h2afx H2A histone family, member X 0.067
senp3a SUMO1/sentrin/SMT3 specific peptidase 3a 0.067
cse1l chromosome segregation 1-like (S. cerevisiae) 0.065
zgc:92775 zgc:92775 0.065
pds5a PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae) 0.064
ywhabb tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b 0.064
zgc:86764 zgc:86764 0.063
zgc:55521 zgc:55521 0.063
csnk1g2a casein kinase 1, gamma 2a 0.062
zgc:136263 zgc:136263 0.062
ovol1 ovo-like 1 (Drosophila) 0.062
zgc:56200 zgc:56200 0.060
zgc:110540 zgc:110540 0.059
prkrir protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor) 0.059
bon bonnie and clyde 0.059
ndr1 nodal-related 1 0.058
cdt1 chromatin licensing and DNA replication factor 1 0.058
tbca tubulin cofactor a 0.058
ptena phosphatase and tensin homolog A 0.058
mga MAX gene associated 0.058
fip1l1 FIP1 like 1 (S. cerevisiae) 0.057
ccne cyclin E 0.056
snx12 sorting nexin 12 0.056
h2afvl H2A histone family, member V, like 0.056
zgc:92321 zgc:92321 0.055
stap2b signal transducing adaptor family member 2b 0.055
kifc1 kinesin family member C1 0.055
uba1 ubiquitin-like modifier activating enzyme 1 0.053
dynlrb1 dynein, light chain, roadblock-type 1 0.053
prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B 0.053
h3f3a H3 histone, family 3A 0.051
zgc:86903 zgc:86903 0.050
si:dkey-9k8.1 si:dkey-9k8.1 0.050
mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.050
nedd8 neural precursor cell expressed, developmentally down-regulated 8 0.050
snx27 sorting nexin family member 27 0.049
fzd7a frizzled homolog 7a 0.049
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
asl asterless 0.761
CycB Cyclin B 0.675
tefu telomere fusion 0.636
CycB3 Cyclin B3 0.551
polo CG12306 gene product from transcript CG12306-RA 0.445
nej nejire 0.413
dup double parked 0.320
Mcm10 Sensitized chromosome inheritance modifier 19 0.280
Aos1 CG12276 gene product from transcript CG12276-RA 0.241
smt3 CG4494 gene product from transcript CG4494-RA 0.237
BubR1 Bub1-related kinase 0.233
sle slender lobes 0.227
Dref DNA replication-related element factor 0.221
CG9772 CG9772 gene product from transcript CG9772-RB 0.215
ncd non-claret disjunctional 0.213
east enhanced adult sensory threshold 0.201
chb chromosome bows 0.186
gwl greatwall 0.176
Sse Separase 0.165
Ras85D Ras oncogene at 85D 0.164
Pp1-87B Protein phosphatase 1 at 87B 0.160
Cdc37 CG12019 gene product from transcript CG12019-RA 0.158
cmet CENP-meta 0.148
cdc2 CG5363 gene product from transcript CG5363-RA 0.132
Klp3A Kinesin-like protein at 3A 0.122
rux roughex 0.119
cid centromere identifier 0.119
hyd hyperplastic discs 0.114
dap dacapo 0.113
Dhc64C Dynein heavy chain 64C 0.102
Egfr Epidermal growth factor receptor 0.092
nbs CG6754 gene product from transcript CG6754-RC 0.090
cdc16 CG6759 gene product from transcript CG6759-RA 0.090
CycA Cyclin A 0.090
mars CG17064 gene product from transcript CG17064-RB 0.089
geminin CG3183 gene product from transcript CG3183-RA 0.086
DNApol-alpha60 DNA polymerase alpha 60kD 0.080
Cap-G CG34438 gene product from transcript CG34438-RF 0.080
pim pimples 0.078
Rbf Retinoblastoma-family protein 0.077
fzy fizzy 0.076
ida imaginal discs arrested 0.076
nod no distributive disjunction 0.075
larp La related protein 0.073
pita CG3941 gene product from transcript CG3941-RA 0.068
Kmn1 kinetochore Mis12-Ndc80 network component 1 0.065
Su(H) Suppressor of Hairless 0.064
Mi-2 CG8103 gene product from transcript CG8103-RA 0.064
pav pavarotti 0.063
pie pineapple eye 0.061
Myb Myb oncogene-like 0.061
bel belle 0.059
fwd four wheel drive 0.056
dsh dishevelled 0.054
Sep2 Septin-2 0.053
Ptp69D Protein tyrosine phosphatase 69D 0.053
Nup153 Nucleoporin 153 0.051
asp abnormal spindle 0.050
msps mini spindles 0.050
flfl falafel 0.049
Cks85A Cyclin-dependent kinase subunit 85A 0.047
Bj1 Bj1 protein 0.047
tum tumbleweed 0.046
Nuf2 CG8902 gene product from transcript CG8902-RA 0.045
lds lodestar 0.045
rod rough deal 0.044
scra scraps 0.044
Spc105R Spc105-related 0.042
wdb widerborst 0.040
CG2926 CG2926 gene product from transcript CG2926-RA 0.038
MCPH1 Microcephalin 0.038
hpo hippo 0.037
Orc5 Origin recognition complex subunit 5 0.037
bam bag of marbles 0.036
Rpd3 CG7471 gene product from transcript CG7471-RA 0.036
Ndc80 CG9938 gene product from transcript CG9938-RA 0.034
brm brahma 0.033
dpa disc proliferation abnormal 0.032
Top1 Topoisomerase 1 0.032
SAK Sak kinase 0.031
Grip84 gamma-tubulin ring protein 84 0.031
mus304 mutagen-sensitive 304 0.030
Bap55 Brahma associated protein 55kD 0.030
dm diminutive 0.030
wee CG4488 gene product from transcript CG4488-RA 0.030
rin rasputin 0.030
arm armadillo 0.029
ana3 anastral spindle 3 0.029
jub Ajuba LIM protein 0.029
p53 CG33336 gene product from transcript CG33336-RB 0.029
CG13742 CG13742 gene product from transcript CG13742-RB 0.029
shtd shattered 0.028
sti sticky 0.028
Det Deterin 0.028
E(z) Enhancer of zeste 0.028
Cenp-C CG31258 gene product from transcript CG31258-RA 0.027
thr three rows 0.027
B52 CG10851 gene product from transcript CG10851-RB 0.027
glu gluon 0.026
PPP4R2r Protein phosphatase 4 regulatory subunit 2-related protein 0.026
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 0.994
Ccnb1 cyclin B1 0.952
Trp53 transformation related protein 53 0.950
Kif20a kinesin family member 20A 0.850
Prc1 protein regulator of cytokinesis 1 0.819
Kif22 kinesin family member 22 0.769
Ccna2 cyclin A2 0.763
Cdk1 cyclin-dependent kinase 1 0.758
Ccne1 cyclin E1 0.745
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.744
Birc5 baculoviral IAP repeat-containing 5 0.726
Ccnb2 cyclin B2 0.725
Gsk3b glycogen synthase kinase 3 beta 0.715
Spag5 sperm associated antigen 5 0.650
Sgol1 shugoshin-like 1 (S. pombe) 0.622
Ube2c ubiquitin-conjugating enzyme E2C 0.520
Cdc6 cell division cycle 6 homolog (S. cerevisiae) 0.436
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.434
Kif11 kinesin family member 11 0.411
Cep55 centrosomal protein 55 0.367
Cenpe centromere protein E 0.355
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.319
Cdca8 cell division cycle associated 8 0.311
Brca1 breast cancer 1 0.275
Ppp1cc protein phosphatase 1, catalytic subunit, gamma isoform 0.265
Ckap2 cytoskeleton associated protein 2 0.258
Melk maternal embryonic leucine zipper kinase 0.247
Axin1 axin 1 0.242
Cdc25c cell division cycle 25 homolog C (S. pombe) 0.229
Ccnf cyclin F 0.212
Mki67 antigen identified by monoclonal antibody Ki 67 0.207
Aurkb aurora kinase B 0.200
Cenpf centromere protein F 0.197
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.180
Kif4 kinesin family member 4 0.174
Cdk2 cyclin-dependent kinase 2 0.167
Depdc1a DEP domain containing 1a 0.167
Stil Scl/Tal1 interrupting locus 0.166
Mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.160
Aurka aurora kinase A 0.148
C330027C09Rik RIKEN cDNA C330027C09 gene 0.144
Sgol2 shugoshin-like 2 (S. pombe) 0.142
Plk1 polo-like kinase 1 (Drosophila) 0.140
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.139
Rac1 RAS-related C3 botulinum substrate 1 0.137
Psen1 presenilin 1 0.134
Ndc80 NDC80 homolog, kinetochore complex component (S. cerevisiae) 0.129
Cdca5 cell division cycle associated 5 0.128
Rad51ap1 RAD51 associated protein 1 0.125
Dtl denticleless homolog (Drosophila) 0.122
Nuf2 NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.118
Racgap1 Rac GTPase-activating protein 1 0.117
Anln anillin, actin binding protein 0.111
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 0.110
Cul4a cullin 4A 0.108
Gsg2 germ cell-specific gene 2 0.107
Wdhd1 WD repeat and HMG-box DNA binding protein 1 0.104
Cenpa centromere protein A 0.103
Lmnb1 lamin B1 0.102
Kif23 kinesin family member 23 0.097
Kif2c kinesin family member 2C 0.091
Cenpn centromere protein N 0.089
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.089
Bmpr1a bone morphogenetic protein receptor, type 1A 0.088
Ccdc99 coiled-coil domain containing 99 0.085
Plk4 polo-like kinase 4 (Drosophila) 0.081
D2Ertd750e DNA segment, Chr 2, ERATO Doi 750, expressed 0.077
Gtse1 G two S phase expressed protein 1 0.076
Ect2 ect2 oncogene 0.074
Apc adenomatosis polyposis coli 0.071
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.071
Mis18bp1 MIS18 binding protein 1 0.070
Pole polymerase (DNA directed), epsilon 0.068
Ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.068
Lin9 lin-9 homolog (C. elegans) 0.064
Rb1 retinoblastoma 1 0.061
2810417H13Rik RIKEN cDNA 2810417H13 gene 0.060
H2afx H2A histone family, member X 0.059
Ccne2 cyclin E2 0.059
Mns1 meiosis-specific nuclear structural protein 1 0.057
Cdkn3 cyclin-dependent kinase inhibitor 3 0.056
Ccnd1 cyclin D1 0.055
Incenp inner centromere protein 0.055
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.053
Mta2 metastasis-associated gene family, member 2 0.053
Ncapg non-SMC condensin I complex, subunit G 0.053
Ooep oocyte expressed protein homolog (dog) 0.053
Fzr1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.052
Cks2 CDC28 protein kinase regulatory subunit 2 0.051
Brca2 breast cancer 2 0.050
E2f8 E2F transcription factor 8 0.048
Rbl1 retinoblastoma-like 1 (p107) 0.048
Suv39h2 suppressor of variegation 3-9 homolog 2 (Drosophila) 0.047
Ptprq protein tyrosine phosphatase, receptor type, Q 0.047
Lrr1 leucine rich repeat protein 1 0.046
Cenpk centromere protein K 0.044
Pold1 polymerase (DNA directed), delta 1, catalytic subunit 0.043
Gja1 gap junction protein, alpha 1 0.043
Rrm2 ribonucleotide reductase M2 0.043
Lrrk2 leucine-rich repeat kinase 2 0.041
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Top2a topoisomerase (DNA) II alpha 0.759
Cdc20 cell division cycle 20 homolog (S. cerevisiae) 0.586
Cdk2 cyclin dependent kinase 2 0.359
Ccnb1 cyclin B1 0.351
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) 0.265
Spag5 sperm associated antigen 5 0.251
Traf4af1 TRAF4 associated factor 1 0.242
Ccnb2 cyclin B2 0.210
Kif2c kinesin family member 2C 0.208
Ccne1 cyclin E1 0.206
LOC689399 hypothetical protein LOC689399 0.206
Rrm2 ribonucleotide reductase M2 0.190
Ube2c ubiquitin-conjugating enzyme E2C 0.181
Racgap1 Rac GTPase-activating protein 1 0.149
Prc1 protein regulator of cytokinesis 1 0.148
Kifc1 kinesin family member C1 0.133
Kif22 kinesin family member 22 0.132
Foxm1 forkhead box M1 0.130
Asf1b ASF1 anti-silencing function 1 homolog B (S. cerevisiae) 0.126
Bub1b budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) 0.122
Plk1 polo-like kinase 1 (Drosophila) 0.122
Hmmr hyaluronan mediated motility receptor (RHAMM) 0.108
Rabac1 Rab acceptor 1 (prenylated) 0.098
Nusap1 nucleolar and spindle associated protein 1 0.095
Lbr lamin B receptor 0.090
Dlgap5 discs, large (Drosophila) homolog-associated protein 5 0.090
Rbbp7 retinoblastoma binding protein 7 0.079
Ska1 spindle and kinetochore associated complex subunit 1 0.069
Cdca8 cell division cycle associated 8 0.069
Ttk Ttk protein kinase 0.064
Cdca2 cell division cycle associated 2 0.052
Aurka aurora kinase A 0.049
Mcm5 minichromosome maintenance complex component 5 0.048
Kif20b kinesin family member 20B 0.048
Ect2 epithelial cell transforming sequence 2 oncogene 0.047
Espl1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.046
Cd82 Cd82 molecule 0.046
Cdkn3 cyclin-dependent kinase inhibitor 3 0.045
Troap trophinin associated protein 0.044
Cbx1 chromobox homolog 1 (HP1 beta homolog Drosophila ) 0.043
Cdca3 cell division cycle associated 3 0.043
Hist1h1a histone cluster 1, H1a 0.043
Pdk2 pyruvate dehydrogenase kinase, isozyme 2 0.041
Melk maternal embryonic leucine zipper kinase 0.041
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.040
Tyms thymidylate synthetase 0.039
Ppm1b protein phosphatase 1B, magnesium dependent, beta isoform 0.037
Pttg1 pituitary tumor-transforming 1 0.037
Litaf lipopolysaccharide-induced TNF factor 0.036
Pcna proliferating cell nuclear antigen 0.036
Kntc1 kinetochore associated 1 0.036
Cenpe centromere protein E 0.035
Cdh1 cadherin 1 0.035
Kif18b kinesin family member 18B 0.035
Tpm4 tropomyosin 4 0.035
Pbk PDZ binding kinase 0.034
Ube2t ubiquitin-conjugating enzyme E2T (putative) 0.034
Kif23 kinesin family member 23 0.033
Rad51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.032
Ckap2 cytoskeleton associated protein 2 0.032
Arf6 ADP-ribosylation factor 6 0.031
Eif2c2 eukaryotic translation initiation factor 2C, 2 0.031
LOC100310874 antisense RNA overlapping MCH 0.029
Birc5 baculoviral IAP repeat-containing 5 0.029
March8 membrane-associated ring finger (C3HC4) 8 0.028
Arhgap11a Rho GTPase activating protein 11A 0.028
Slain2 SLAIN motif family, member 2 0.028
Nr3c2 nuclear receptor subfamily 3, group C, member 2 0.027
Ppard peroxisome proliferator-activated receptor delta 0.026
Haus4 HAUS augmin-like complex, subunit 4 0.025
Hist1h1d histone cluster 1, H1d 0.025
Akap11 A kinase (PRKA) anchor protein 11 0.025
Scaf1 SR-related CTD-associated factor 1 0.023
Ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.023
Btg1 B-cell translocation gene 1, anti-proliferative 0.023
Clcn3 chloride channel 3 0.022
Hdac2 histone deacetylase 2 0.022
Wbp2 WW domain binding protein 2 0.022
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.021
Ube2i ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.021
Basp1 brain abundant, membrane attached signal protein 1 0.021
Pgam2 phosphoglycerate mutase 2 (muscle) 0.021
E2f1 E2F transcription factor 1 0.020
Taok2 TAO kinase 2 0.020
Zfp91 zinc finger protein 91 0.020
Mbd2 methyl-CpG binding domain protein 2 0.020
Brca2 breast cancer 2 0.020
Cenpt centromere protein T 0.019
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.019
Zmym2 zinc finger, MYM-type 2 0.019
Klhl24 kelch-like 24 (Drosophila) 0.019
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.019
Mtdh metadherin 0.018
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.018
Ctnnb1 catenin (cadherin associated protein), beta 1 0.018
Depdc1b DEP domain containing 1B 0.018
Dhfr dihydrofolate reductase 0.018
Myh10 myosin, heavy chain 10, non-muscle 0.017
Tmpo thymopoietin 0.017
Ppp4r2 protein phosphatase 4, regulatory subunit 2 0.017
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
DAM1 Dam1p 0.997
ASK1 Ask1p 0.995
CDC16 Cdc16p 0.986
CDC20 Cdc20p 0.985
MAD2 Mad2p 0.975
DAD4 Dad4p 0.967
DOC1 Doc1p 0.966
HSK3 Hsk3p 0.954
SPC34 Spc34p 0.938
CDC27 Cdc27p 0.937
DSN1 Dsn1p 0.929
CDC26 Cdc26p 0.928
TID3 Tid3p 0.925
PPH21 Pph21p 0.923
PPH22 Pph22p 0.912
CSE4 Cse4p 0.910
DUO1 Duo1p 0.869
CDC23 Cdc23p 0.862
SPC19 Spc19p 0.856
DAD2 Dad2p 0.844
SLI15 Sli15p 0.842
BUB3 Bub3p 0.840
DAD1 Dad1p 0.829
MTW1 Mtw1p 0.750
IML3 Iml3p 0.733
GLC7 Glc7p 0.713
CDC55 Cdc55p 0.670
APC1 Apc1p 0.666
BUB1 Bub1p 0.635
DAD3 Dad3p 0.571
RTS1 Rts1p 0.530
APC4 Apc4p 0.530
NSL1 Nsl1p 0.495
CLB3 Clb3p 0.479
SLK19 Slk19p 0.468
HTA1 Hta1p 0.456
SPC105 Spc105p 0.420
CDC28 Cdc28p 0.411
APC2 Apc2p 0.402
CDH1 Cdh1p 0.399
MAD1 Mad1p 0.390
CHL4 Chl4p 0.374
TIP41 Tip41p 0.361
MAD3 Mad3p 0.351
PDS1 Pds1p 0.343
MCM21 Mcm21p 0.339
CTF3 Ctf3p 0.320
NUF2 Nuf2p 0.278
MPS1 Mps1p 0.253
CLB1 Clb1p 0.240
MCM22 Mcm22p 0.234
APC5 Apc5p 0.230
STE4 Ste4p 0.226
SPC25 Spc25p 0.216
PIG2 Pig2p 0.215
SPC24 Spc24p 0.198
HHF2 Hhf2p 0.197
SDS22 Sds22p 0.196
MND2 Mnd2p 0.190
IPL1 Ipl1p 0.190
SWM1 Swm1p 0.180
FMP48 Fmp48p 0.180
SMC4 Smc4p 0.159
CKS1 Cks1p 0.149
CLB4 Clb4p 0.145
CTF19 Ctf19p 0.134
HSL1 Hsl1p 0.124
KIP1 Kip1p 0.121
CDC5 Cdc5p 0.119
IRC15 Irc15p 0.119
IES1 Ies1p 0.119
CIN8 Cin8p 0.104
PPZ1 Ppz1p 0.101
PPQ1 Ppq1p 0.099
CLB6 Clb6p 0.096
ARP4 Arp4p 0.087
GSY1 Gsy1p 0.086
INO80 Ino80p 0.086
PRP28 Prp28p 0.082
NNF1 Nnf1p 0.081
KEL1 Kel1p 0.078
APC11 Apc11p 0.077
IES3 Ies3p 0.072
BFA1 Bfa1p 0.070
NBL1 Nbl1p 0.070
CBF1 Cbf1p 0.069
ARP8 Arp8p 0.068
MMS21 Mms21p 0.068
OKP1 Okp1p 0.066
GIP2 Gip2p 0.058
MIF2 Mif2p 0.058
PSP1 Psp1p 0.057
DCC1 Dcc1p 0.057
SIC1 Sic1p 0.056
MDM20 Mdm20p 0.051
CCT2 Cct2p 0.048
HHT2 Hht2p 0.048
KAR3 Kar3p 0.046
BUD8 Bud8p 0.045
CBF2 Cbf2p 0.045