The network for 'purine containing compound catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine containing compound catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.

Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.999
GRB7 growth factor receptor-bound protein 7 0.997
GRB2 growth factor receptor-bound protein 2 0.997
SNX9 sorting nexin 9 0.996
SFN stratifin 0.992
RABAC1 Rab acceptor 1 (prenylated) 0.986
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.985
ARRB1 arrestin, beta 1 0.984
SH3KBP1 SH3-domain kinase binding protein 1 0.978
ITSN1 intersectin 1 (SH3 domain protein) 0.976
PTK2 PTK2 protein tyrosine kinase 2 0.974
RAB1A RAB1A, member RAS oncogene family 0.973
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.970
CDK7 cyclin-dependent kinase 7 0.968
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.967
RACGAP1 Rac GTPase activating protein 1 0.961
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.951
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.948
TMSB4X thymosin beta 4, X-linked 0.944
OCRL oculocerebrorenal syndrome of Lowe 0.938
DNM2 dynamin 2 0.934
NCK2 NCK adaptor protein 2 0.927
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.920
SRPK1 SRSF protein kinase 1 0.919
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.911
TOR1A torsin family 1, member A (torsin A) 0.899
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.898
DNM1 dynamin 1 0.898
ILK integrin-linked kinase 0.895
RHOA ras homolog gene family, member A 0.892
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.891
LRRK2 leucine-rich repeat kinase 2 0.882
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.877
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.869
TNNC1 troponin C type 1 (slow) 0.865
HSPA1B heat shock 70kDa protein 1B 0.863
NCKAP1 NCK-associated protein 1 0.856
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.855
RAB5A RAB5A, member RAS oncogene family 0.840
SOS1 son of sevenless homolog 1 (Drosophila) 0.838
FASLG Fas ligand (TNF superfamily, member 6) 0.830
S100A8 S100 calcium binding protein A8 0.828
VIM vimentin 0.828
TSC2 tuberous sclerosis 2 0.814
UNC119 unc-119 homolog (C. elegans) 0.813
CCNH cyclin H 0.810
TK1 thymidine kinase 1, soluble 0.804
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.795
TRAF5 TNF receptor-associated factor 5 0.790
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.781
ABI1 abl-interactor 1 0.780
MARK3 MAP/microtubule affinity-regulating kinase 3 0.776
RHEB Ras homolog enriched in brain 0.765
BLM Bloom syndrome, RecQ helicase-like 0.765
APC adenomatous polyposis coli 0.765
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.758
FGFR2 fibroblast growth factor receptor 2 0.758
S100A6 S100 calcium binding protein A6 0.756
THOC4 THO complex 4 0.754
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.753
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.746
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A 0.745
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.741
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.733
BCL2L1 BCL2-like 1 0.733
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.728
PLCG1 phospholipase C, gamma 1 0.716
GDI2 GDP dissociation inhibitor 2 0.711
PKN3 protein kinase N3 0.711
SS18 synovial sarcoma translocation, chromosome 18 0.710
CCL3 chemokine (C-C motif) ligand 3 0.699
SMC4 structural maintenance of chromosomes 4 0.697
CCR5 chemokine (C-C motif) receptor 5 0.697
IGF1R insulin-like growth factor 1 receptor 0.691
FAF1 Fas (TNFRSF6) associated factor 1 0.665
MPRIP myosin phosphatase Rho interacting protein 0.663
RRAGA Ras-related GTP binding A 0.655
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.650
MYCBP2 MYC binding protein 2 0.648
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.645
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.641
NCF2 neutrophil cytosolic factor 2 0.641
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.640
TRIM63 tripartite motif containing 63 0.640
SQSTM1 sequestosome 1 0.636
S100A1 S100 calcium binding protein A1 0.629
SEPT7 septin 7 0.623
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.620
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.618
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.617
S100B S100 calcium binding protein B 0.617
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.596
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.596
MICALL1 MICAL-like 1 0.592
TPM1 tropomyosin 1 (alpha) 0.582
YY1 YY1 transcription factor 0.582
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.935
sem-5 Protein SEM-5 0.573
abts-1 Protein ABTS-1 0.555
let-60 Protein LET-60 0.513
rod-1 Protein ROD-1 0.478
unc-45 Protein UNC-45 0.409
pkg-1 Protein PKG-1 0.388
rhgf-2 Protein RHGF-2 0.377
D1081.8 Protein D1081.8 0.366
plc-3 Protein PLC-3 0.366
gpr-1 Protein GPR-1 0.331
gpr-2 Protein GPR-2 0.274
vav-1 Protein VAV-1 0.265
ula-1 Protein ULA-1 0.265
lfi-1 Protein LFI-1 0.263
bmk-1 Protein BMK-1 0.249
kin-2 Protein KIN-2 0.245
chc-1 Protein CHC-1 0.244
lin-5 Protein LIN-5 0.228
gpb-1 Protein GPB-1 0.227
sax-3 Protein SAX-3 0.220
C50F2.3 Protein C50F2.3 0.213
snf-1 Protein SNF-1 0.210
cyk-4 Protein CYK-4 0.206
coh-3 Protein COH-3 0.201
gei-18 Protein GEI-18 0.198
smc-4 Protein SMC-4 0.196
ima-2 Protein IMA-2 0.185
apg-1 Protein APG-1 0.185
csr-1 Protein CSR-1 0.181
sas-5 Protein SAS-5 0.178
hsp-16.41 Protein HSP-16.41 0.178
etr-1 Protein ETR-1 0.174
ucr-2.3 Protein UCR-2.3 0.173
ret-1 Protein RET-1 0.171
F35A5.1 Protein F35A5.1 0.165
ubr-1 Protein UBR-1 0.165
F22D3.2 Protein F22D3.2 0.164
rab-5 Protein RAB-5 0.160
CELE_F29C4.2 Protein F29C4.2 0.159
dpf-3 Protein DPF-3 0.158
sas-4 Protein SAS-4 0.157
spdl-1 Protein SPDL-1 0.156
snr-3 Protein SNR-3 0.155
F29B9.8 Protein F29B9.8 0.153
unc-71 Protein UNC-71 0.151
pdl-1 Protein PDL-1 0.150
pme-1 Protein PME-1 0.149
F35G2.1 Protein F35G2.1 0.143
hmr-1 Protein HMR-1 0.143
frm-7 Protein FRM-7 0.140
aip-1 Protein AIP-1 0.136
CELE_Y106G6D.7 Protein Y106G6D.7 0.136
pat-12 Protein PAT-12 0.135
CELE_F47G4.4 Protein F47G4.4 0.134
akt-1 Protein AKT-1 0.134
pptr-2 Protein PPTR-2 0.130
ric-8 Protein RIC-8 0.129
unc-54 Protein UNC-54 0.129
ddx-23 Protein DDX-23 0.127
C53C9.2 Protein C53C9.2 0.125
itr-1 Protein ITR-1 0.125
nfx-1 Protein NFX-1 0.124
lin-10 Protein LIN-10 0.124
CELE_Y60A3A.9 Protein Y60A3A.9 0.123
C35D10.6 Protein C35D10.6 0.122
F44E5.1 Protein F44E5.1 0.122
F11E6.7 Protein F11E6.7 0.122
cct-2 Protein CCT-2 0.120
rme-4 Protein RME-4 0.119
gei-4 Protein GEI-4 0.119
B0495.2 Protein B0495.2 0.118
mei-1 Protein MEI-1 0.117
zyg-9 Protein ZYG-9 0.115
ttx-1 Protein TTX-1 0.114
cmd-1 Protein CMD-1 0.113
nasp-2 Protein NASP-2 0.112
scc-1 Protein SCC-1 0.111
acl-11 Protein ACL-11 0.109
F20A1.9 Protein F20A1.9 0.109
vab-10 Protein VAB-10 0.109
ife-2 Protein IFE-2 0.107
T23F11.1 Protein T23F11.1 0.107
F33E11.3 Protein F33E11.3 0.105
fkb-6 Protein FKB-6 0.104
gln-1 Protein GLN-1 0.104
glh-4 Protein GLH-4 0.103
vhp-1 Protein VHP-1 0.102
CELE_Y116A8C.26 Protein Y116A8C.26 0.102
spd-2 Protein SPD-2 0.102
emb-5 Protein EMB-5 0.101
CELE_W03F9.10 Protein W03F9.10 0.101
R11A8.7 Protein R11A8.7 0.100
CELE_C08H9.2 Protein C08H9.2 0.099
jnk-1 Protein JNK-1 0.097
CELE_F08D12.1 Protein F08D12.1 0.097
snrp-200 Protein SNRP-200 0.096
csnk-1 Protein CSNK-1 0.096
kcc-1 Protein KCC-1 0.095
mig-6 Protein MIG-6 0.095
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.980
Rheb CG1081 gene product from transcript CG1081-RA 0.941
Moe Moesin 0.742
Rac1 CG2248 gene product from transcript CG2248-RA 0.703
Uba1 Ubiquitin activating enzyme 1 0.692
Pten CG5671 gene product from transcript CG5671-RB 0.674
drk downstream of receptor kinase 0.671
WASp CG1520 gene product from transcript CG1520-RA 0.657
Rho1 CG8416 gene product from transcript CG8416-RB 0.643
puc puckered 0.571
chic chickadee 0.500
tsr twinstar 0.498
didum dilute class unconventional myosin 0.466
Myo31DF Myosin 31DF 0.451
zip zipper 0.431
sun stunted 0.387
S6k RPS6-p70-protein kinase 0.386
shi shibire 0.343
ttk tramtrack 0.336
cenG1A centaurin gamma 1A 0.322
Ras85D Ras oncogene at 85D 0.319
Pk61C Protein kinase 61C 0.312
Khc Kinesin heavy chain 0.311
ben bendless 0.309
gfA giant fibre A 0.306
RpS3 Ribosomal protein S3 0.301
trio CG18214 gene product from transcript CG18214-RA 0.299
cpa capping protein alpha 0.291
loco locomotion defects 0.288
Rab11 Rab-protein 11 0.278
E(bx) Enhancer of bithorax 0.276
E(z) Enhancer of zeste 0.276
baz bazooka 0.261
trp transient receptor potential 0.251
cno canoe 0.248
mbc myoblast city 0.240
mask multiple ankyrin repeats single KH domain 0.239
flw flapwing 0.234
mys myospheroid 0.230
Pkn Protein kinase related to protein kinase N 0.225
arm armadillo 0.223
gcl germ cell-less 0.221
Arf79F ADP ribosylation factor 79F 0.219
MTF-1 Metal response element-binding Transcription Factor-1 0.216
Tsc1 CG6147 gene product from transcript CG6147-RA 0.216
Oscp Oligomycin sensitivity-conferring protein 0.208
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.204
plexB plexin B 0.203
HLH106 Helix loop helix protein 106 0.199
rictor rapamycin-insensitive companion of Tor 0.199
porin CG6647 gene product from transcript CG6647-RA 0.189
Eip63E Ecdysone-induced protein 63E 0.188
stumps CG31317 gene product from transcript CG31317-RC 0.188
CG11376 CG11376 gene product from transcript CG11376-RA 0.185
dys dysfusion 0.184
Snap25 Synapse protein 25 0.184
Wnk CG7177 gene product from transcript CG7177-RA 0.183
rok Rho-kinase 0.182
Syx7 Syntaxin 7 0.180
dm diminutive 0.179
wupA wings up A 0.179
pod1 CG4532 gene product from transcript CG4532-RF 0.178
Lis-1 Lissencephaly-1 0.176
asf1 anti-silencing factor 1 0.169
Mad Mothers against dpp 0.166
NaCP60E Na channel protein 60E 0.163
Ced-12 CG5336 gene product from transcript CG5336-RA 0.161
Caps Calcium activated protein for secretion 0.161
garz gartenzwerg 0.160
Fak56D Focal Adhesion Kinase 0.159
rhea CG6831 gene product from transcript CG6831-RA 0.158
Cip4 CG15015 gene product from transcript CG15015-RA 0.157
neuroligin CG13772 gene product from transcript CG13772-RA 0.155
Dhc64C Dynein heavy chain 64C 0.154
Pak PAK-kinase 0.153
shrb shrub 0.151
rl rolled 0.151
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.150
Su(var)3-7 Suppressor of variegation 3-7 0.148
Rbsn-5 Rabenosyn-5 0.146
Dlic Dynein light intermediate chain 0.145
tkv thickveins 0.145
Taf1 TBP-associated factor 1 0.143
Gie novel GTPase indispensable for equal segregation of chromosomes 0.143
Dcr-2 Dicer-2 0.140
dos daughter of sevenless 0.136
mbt mushroom bodies tiny 0.133
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.133
ik2 IkappaB kinase-like 2 0.132
mit(1)15 mitotic 15 0.132
Jra Jun-related antigen 0.131
Hnf4 Hepatocyte nuclear factor 4 0.131
Stat92E Signal-transducer and activator of transcription protein at 92E 0.131
Gap69C GTPase-activating protein 69C 0.129
Pp2B-14D Protein phosphatase 2B at 14D 0.127
SNF1A SNF1A/AMP-activated protein kinase 0.126
kibra kibra ortholog 0.125
Xbp1 X box binding protein-1 0.124
neb nebbish 0.124
Gyc-89Da Guanylyl cyclase at 89Da 0.122
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Mus musculus
Name Description Probability Func Analog Organism
Braf Braf transforming gene 0.949
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.935
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.921
Rac1 RAS-related C3 botulinum substrate 1 0.903
Tnnt3 troponin T3, skeletal, fast 0.886
Ephb2 Eph receptor B2 0.884
Kl klotho 0.803
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.791
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.777
Arrb2 arrestin, beta 2 0.777
Epha4 Eph receptor A4 0.777
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.761
Lrrk2 leucine-rich repeat kinase 2 0.752
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.751
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.749
Igtp interferon gamma induced GTPase 0.745
Spna2 spectrin alpha 2 0.744
Ntf3 neurotrophin 3 0.738
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.737
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.714
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.708
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.672
Adrb1 adrenergic receptor, beta 1 0.655
Plxna1 plexin A1 0.647
Rab1 RAB1, member RAS oncogene family 0.644
Pxn paxillin 0.643
Ret ret proto-oncogene 0.639
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.635
Eea1 early endosome antigen 1 0.633
Bcl2 B-cell leukemia/lymphoma 2 0.618
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.613
Des desmin 0.604
Shc3 src homology 2 domain-containing transforming protein C3 0.597
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.593
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.573
Iigp1 interferon inducible GTPase 1 0.560
Akt1 thymoma viral proto-oncogene 1 0.544
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.541
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.535
Ifi47 interferon gamma inducible protein 47 0.529
Smarcc1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 0.524
Plxnb1 plexin B1 0.522
Git1 G protein-coupled receptor kinase-interactor 1 0.522
Kif5b kinesin family member 5B 0.513
Cd44 CD44 antigen 0.509
Npas2 neuronal PAS domain protein 2 0.507
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.497
Lrp6 low density lipoprotein receptor-related protein 6 0.495
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.492
Nf1 neurofibromatosis 1 0.486
Efnb2 ephrin B2 0.482
Rab5a RAB5A, member RAS oncogene family 0.464
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.459
Syn2 synapsin II 0.459
Src Rous sarcoma oncogene 0.458
Prkce protein kinase C, epsilon 0.449
Dock1 dedicator of cytokinesis 1 0.447
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 0.440
Tgtp2 T-cell specific GTPase 2 0.438
Cyfip1 cytoplasmic FMR1 interacting protein 1 0.431
Myo18a myosin XVIIIA 0.430
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.426
Hrc histidine rich calcium binding protein 0.425
Dlg4 discs, large homolog 4 (Drosophila) 0.420
Plcb1 phospholipase C, beta 1 0.417
Gbp2 guanylate binding protein 2 0.414
Vapa vesicle-associated membrane protein, associated protein A 0.411
Irgm2 immunity-related GTPase family M member 2 0.410
Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.405
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.401
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.400
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.400
Rasgrp2 RAS, guanyl releasing protein 2 0.395
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.388
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.387
Neurl1a neuralized homolog 1A (Drosophila) 0.386
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.381
Ilk integrin linked kinase 0.379
Gbp3 guanylate binding protein 3 0.377
Hnf1b HNF1 homeobox B 0.372
Ctnnb1 catenin (cadherin associated protein), beta 1 0.369
Myo1c myosin IC 0.368
Spry4 sprouty homolog 4 (Drosophila) 0.367
Kifc2 kinesin family member C2 0.364
Stat1 signal transducer and activator of transcription 1 0.358
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.353
Dnm1 dynamin 1 0.352
Rictor RPTOR independent companion of MTOR, complex 2 0.350
Stx12 syntaxin 12 0.347
Srsf9 serine/arginine-rich splicing factor 9 0.342
L1cam L1 cell adhesion molecule 0.341
Rplp0 ribosomal protein, large, P0 0.341
Ly6h lymphocyte antigen 6 complex, locus H 0.336
Rtkn rhotekin 0.335
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.334
Rpgrip1l Rpgrip1-like 0.331
Rasgrp1 RAS guanyl releasing protein 1 0.331
Klf7 Kruppel-like factor 7 (ubiquitous) 0.331
Tnni2 troponin I, skeletal, fast 2 0.331
Lyst lysosomal trafficking regulator 0.331
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Rattus norvegicus
Name Description Probability Func Analog Organism
Rhoa ras homolog gene family, member A 0.825
Arl1 ADP-ribosylation factor-like 1 0.784
Amph amphiphysin 0.761
S100a10 S100 calcium binding protein A10 0.717
Anxa2 annexin A2 0.553
Pja2 praja 2, RING-H2 motif containing 0.485
Syn1 synapsin I 0.377
Scarb1 scavenger receptor class B, member 1 0.366
Pdcl phosducin-like 0.362
Myo1d myosin ID 0.349
Rab1 RAB1, member RAS oncogene family 0.343
Tagln2 transgelin 2 0.316
Tpm4 tropomyosin 4 0.300
Lman1 lectin, mannose-binding, 1 0.299
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.297
Pfn1 profilin 1 0.295
Anxa1 annexin A1 0.293
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.271
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.266
Myl9 myosin, light chain 9, regulatory 0.257
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.248
Ifitm3 interferon induced transmembrane protein 3 0.248
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.242
Sh3gl2 SH3-domain GRB2-like 2 0.242
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.241
Gria2 glutamate receptor, ionotropic, AMPA 2 0.219
Acta2 smooth muscle alpha-actin 0.217
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.210
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.203
Arpc1b actin related protein 2/3 complex, subunit 1B 0.203
Lmna lamin A 0.202
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.201
Cmklr1 chemokine-like receptor 1 0.197
Capn2 calpain 2 0.196
Gdi2 GDP dissociation inhibitor 2 0.195
Camk4 calcium/calmodulin-dependent protein kinase IV 0.191
Hk1 hexokinase 1 0.189
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.183
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.183
Vim vimentin 0.179
Gipc1 GIPC PDZ domain containing family, member 1 0.179
Mybpc2 myosin binding protein C, fast-type 0.177
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.176
Rap1b RAP1B, member of RAS oncogene family 0.173
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.172
Svop SV2 related protein 0.172
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.169
Hand2 heart and neural crest derivatives expressed 2 0.165
Dlg3 discs, large homolog 3 (Drosophila) 0.164
Cdc42 cell division cycle 42 (GTP binding protein) 0.160
Arhgap9 Rho GTPase activating protein 9 0.159
Ndufb3 NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3 0.158
S100a11 S100 calcium binding protein A11 (calizzarin) 0.158
Prkch protein kinase C, eta 0.157
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.156
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.155
Pls3 plastin 3 (T-isoform) 0.155
Nckap1 NCK-associated protein 1 0.153
Chrm3 cholinergic receptor, muscarinic 3 0.153
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.150
Camk1g calcium/calmodulin-dependent protein kinase IG 0.144
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.143
Uso1 USO1 homolog, vesicle docking protein (yeast) 0.143
Myadm myeloid-associated differentiation marker 0.143
Copb1 coatomer protein complex, subunit beta 1 0.141
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.139
Prkcb protein kinase C, beta 0.138
RGD1309543 similar to 2310014H01Rik protein 0.136
Lgals3 lectin, galactoside-binding, soluble, 3 0.133
Barhl2 BarH-like homeobox 2 0.132
Eif5 eukaryotic translation initiation factor 5 0.132
Utrn utrophin 0.130
Anapc5 anaphase-promoting complex subunit 5 0.129
Myl12b myosin, light chain 12B, regulatory 0.128
Rhoc ras homolog gene family, member C 0.127
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.126
Homer1 homer homolog 1 (Drosophila) 0.125
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.125
Jtb jumping translocation breakpoint 0.125
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.123
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.123
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.122
Cnn1 calponin 1, basic, smooth muscle 0.122
Cdk7 cyclin-dependent kinase 7 0.122
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.120
Tagln transgelin 0.120
Csk c-src tyrosine kinase 0.118
Jak2 Janus kinase 2 0.118
S100a6 S100 calcium binding protein A6 0.117
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 0.117
Tmed2 transmembrane emp24 domain trafficking protein 2 0.116
Grasp GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein 0.115
Clec11a C-type lectin domain family 11, member a 0.115
Klf6 Kruppel-like factor 6 0.114
Syngr3 synaptogyrin 3 0.114
Shank2 SH3 and multiple ankyrin repeat domains 2 0.113
Mapk3 mitogen activated protein kinase 3 0.112
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.112
Stxbp1 syntaxin binding protein 1 0.111
Pam peptidylglycine alpha-amidating monooxygenase 0.110
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
BEM3 Bem3p 0.656
YPT52 Ypt52p 0.650
SSL1 Ssl1p 0.647
RHO1 Rho1p 0.587
YPT1 Ypt1p 0.532
ROM2 Rom2p 0.499
STI1 Sti1p 0.445
POL30 Pol30p 0.404
SUI3 Sui3p 0.386
CCL1 Ccl1p 0.377
MKK1 Mkk1p 0.335
AVO1 Avo1p 0.318
TFB4 Tfb4p 0.316
TSR1 Tsr1p 0.291
KIN28 Kin28p 0.274
KAR2 Kar2p 0.268
SEC53 Sec53p 0.257
VPS15 Vps15p 0.254
STE5 Ste5p 0.248
ISW1 Isw1p 0.247
SIS1 Sis1p 0.244
STE4 Ste4p 0.243
GYL1 Gyl1p 0.227
NOG2 Nog2p 0.221
PRP8 Prp8p 0.218
YCS4 Ycs4p 0.217
STT4 Stt4p 0.213
PEX1 Pex1p 0.208
TFB1 Tfb1p 0.205
SGT2 Sgt2p 0.204
MSB3 Msb3p 0.203
MYO3 Myo3p 0.199
SSA4 Ssa4p 0.197
RRP1 Rrp1p 0.184
YPT7 Ypt7p 0.183
PKH2 Pkh2p 0.179
ESP1 Esp1p 0.179
SEC13 Sec13p 0.178
STE2 Ste2p 0.178
YIP3 Yip3p 0.177
YPT53 Ypt53p 0.176
RLF2 Rlf2p 0.171
RSC9 Rsc9p 0.169
SEC16 Sec16p 0.169
BEM4 Bem4p 0.167
YDJ1 Ydj1p 0.165
CDC24 Cdc24p 0.159
CDC48 Cdc48p 0.155
BFR1 Bfr1p 0.154
STE11 Ste11p 0.151
TRS65 Trs65p 0.150
SWI1 Swi1p 0.149
PIM1 Pim1p 0.144
TSC11 Tsc11p 0.142
YPT10 Ypt10p 0.141
VPS4 Vps4p 0.140
GCD6 Gcd6p 0.140
SNF12 Snf12p 0.140
UNG1 Ung1p 0.139
ACK1 Ack1p 0.138
RAS1 Ras1p 0.138
RPT6 Rpt6p 0.138
MKT1 Mkt1p 0.134
RAD4 Rad4p 0.133
SEC4 Sec4p 0.132
RTT106 Rtt106p 0.130
VPS21 Vps21p 0.128
FKH1 Fkh1p 0.127
SEC2 Sec2p 0.126
TFB3 Tfb3p 0.126
CDS1 Cds1p 0.126
RPT3 Rpt3p 0.126
PXA1 Pxa1p 0.124
BOI1 Boi1p 0.124
IRA1 Ira1p 0.124
MON2 Mon2p 0.123
CRN1 Crn1p 0.121
RAD27 Rad27p 0.121
RFC1 Rfc1p 0.121
SLA2 Sla2p 0.120
MYO4 Myo4p 0.120
SEC24 Sec24p 0.119
RSC6 Rsc6p 0.117
VTA1 Vta1p 0.114
HSP104 Hsp104p 0.114
GDI1 Gdi1p 0.114
MOT1 Mot1p 0.114
ORC4 Orc4p 0.112
CHS1 Chs1p 0.111
LSM5 Lsm5p 0.110
YLR173W hypothetical protein 0.109
BRO1 Bro1p 0.109
SAR1 Sar1p 0.108
PTP2 Ptp2p 0.108
RAD23 Rad23p 0.108
YDL073W hypothetical protein 0.108
ARX1 Arx1p 0.107
RAD53 Rad53p 0.107
SPA2 Spa2p 0.106
MDR1 Mdr1p 0.106