The network for 'negative regulation of cytokine production involved in immune response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of cytokine production involved in immune response

Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.

Homo sapiens
Name Description Probability Func Analog Organism
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 0.983
ALB albumin 0.975
CCR5 chemokine (C-C motif) receptor 5 0.970
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.956
CCL4 chemokine (C-C motif) ligand 4 0.909
PILRA paired immunoglobin-like type 2 receptor alpha 0.828
CXCL9 chemokine (C-X-C motif) ligand 9 0.726
LILRA1 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 0.699
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 0.657
CCL5 chemokine (C-C motif) ligand 5 0.623
CCR1 chemokine (C-C motif) receptor 1 0.591
HK3 hexokinase 3 (white cell) 0.532
HP haptoglobin 0.492
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 0.448
IL10RA interleukin 10 receptor, alpha 0.432
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.431
SIGLEC7 sialic acid binding Ig-like lectin 7 0.426
CCL8 chemokine (C-C motif) ligand 8 0.414
IL1B interleukin 1, beta 0.390
APOC1 apolipoprotein C-I 0.375
IFNG interferon, gamma 0.345
IRAK2 interleukin-1 receptor-associated kinase 2 0.305
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.277
IL22RA1 interleukin 22 receptor, alpha 1 0.258
A2M alpha-2-macroglobulin 0.253
IDE insulin-degrading enzyme 0.237
CCL22 chemokine (C-C motif) ligand 22 0.210
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 0.206
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 0.200
CCR7 chemokine (C-C motif) receptor 7 0.197
IL22RA2 interleukin 22 receptor, alpha 2 0.193
DPP4 dipeptidyl-peptidase 4 0.183
CCL7 chemokine (C-C motif) ligand 7 0.147
CCL13 chemokine (C-C motif) ligand 13 0.132
TNFRSF9 tumor necrosis factor receptor superfamily, member 9 0.130
APOA1 apolipoprotein A-I 0.120
CCR4 chemokine (C-C motif) receptor 4 0.116
CCL3 chemokine (C-C motif) ligand 3 0.104
CCL2 chemokine (C-C motif) ligand 2 0.104
CXCL10 chemokine (C-X-C motif) ligand 10 0.103
PTAFR platelet-activating factor receptor 0.102
SOCS3 suppressor of cytokine signaling 3 0.099
NLRP3 NLR family, pyrin domain containing 3 0.091
CXCL13 chemokine (C-X-C motif) ligand 13 0.090
TREM1 triggering receptor expressed on myeloid cells 1 0.088
FPR3 formyl peptide receptor 3 0.086
EBI3 Epstein-Barr virus induced 3 0.084
HDAC9 histone deacetylase 9 0.080
TGFB1 transforming growth factor, beta 1 0.076
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.075
IL8 interleukin 8 0.074
ENG endoglin 0.070
CXCL11 chemokine (C-X-C motif) ligand 11 0.069
CD14 CD14 molecule 0.068
CCL19 chemokine (C-C motif) ligand 19 0.066
CD80 CD80 molecule 0.066
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.064
IL6 interleukin 6 (interferon, beta 2) 0.061
IL10 interleukin 10 0.061
IL2RB interleukin 2 receptor, beta 0.061
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 0.060
IL1RN interleukin 1 receptor antagonist 0.060
FSTL1 follistatin-like 1 0.059
CD86 CD86 molecule 0.058
LTA lymphotoxin alpha (TNF superfamily, member 1) 0.057
IL18RAP interleukin 18 receptor accessory protein 0.056
CXCL2 chemokine (C-X-C motif) ligand 2 0.054
TYMP thymidine phosphorylase 0.053
AQP9 aquaporin 9 0.051
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.046
PRF1 perforin 1 (pore forming protein) 0.043
CCL11 chemokine (C-C motif) ligand 11 0.041
SLAMF7 SLAM family member 7 0.040
PCDH9 protocadherin 9 0.039
MMP9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) 0.039
APOC2 apolipoprotein C-II 0.039
IRF4 interferon regulatory factor 4 0.038
ANGPT2 angiopoietin 2 0.033
CXCL3 chemokine (C-X-C motif) ligand 3 0.030
C2 complement component 2 0.030
LCAT lecithin-cholesterol acyltransferase 0.030
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.030
LILRA3 leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 0.029
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.029
IL2RG interleukin 2 receptor, gamma 0.028
CXCL5 chemokine (C-X-C motif) ligand 5 0.027
FPR2 formyl peptide receptor 2 0.027
ICAM1 intercellular adhesion molecule 1 0.027
NRP1 neuropilin 1 0.026
TNF tumor necrosis factor 0.026
EPOR erythropoietin receptor 0.026
TEK TEK tyrosine kinase, endothelial 0.026
CCR3 chemokine (C-C motif) receptor 3 0.026
FCN1 ficolin (collagen/fibrinogen domain containing) 1 0.025
AKT2 v-akt murine thymoma viral oncogene homolog 2 0.025
CCL1 chemokine (C-C motif) ligand 1 0.025
SPI1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.024
BATF basic leucine zipper transcription factor, ATF-like 0.023
CMKLR1 chemokine-like receptor 1 0.023
FCAR Fc fragment of IgA, receptor for 0.023
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Traf6 TNF receptor-associated factor 6 0.574
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.276
Myd88 myeloid differentiation primary response gene 88 0.169
Stat3 signal transducer and activator of transcription 3 0.092
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.072
Il2 interleukin 2 0.066
Fas Fas (TNF receptor superfamily member 6) 0.052
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.045
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.041
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.039
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.035
Ikzf1 IKAROS family zinc finger 1 0.033
Tnf tumor necrosis factor 0.026
Socs1 suppressor of cytokine signaling 1 0.023
Rag1 recombination activating gene 1 0.021
Ptprc protein tyrosine phosphatase, receptor type, C 0.021
Il2rg interleukin 2 receptor, gamma chain 0.018
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.015
Aire autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) 0.015
Il6st interleukin 6 signal transducer 0.014
Foxp3 forkhead box P3 0.013
Ifng interferon gamma 0.013
Lyz2 lysozyme 2 0.012
Jak2 Janus kinase 2 0.011
Tcra T-cell receptor alpha chain 0.011
Elavl1 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) 0.010
Irak4 interleukin-1 receptor-associated kinase 4 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism