IMP
Process View
The network for 'cd8 positive alpha beta t cell activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cd8 positive alpha beta t cell activation
The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 1.000 | |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | 0.999 | |
| PILRA | paired immunoglobin-like type 2 receptor alpha | 0.998 | |
| LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.993 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.993 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.969 | |
| LILRB2 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2 | 0.963 | |
| IDE | insulin-degrading enzyme | 0.957 | |
| IL8 | interleukin 8 | 0.954 | |
| LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.887 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.872 | |
| PTAFR | platelet-activating factor receptor | 0.871 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.832 | |
| IL1B | interleukin 1, beta | 0.829 | |
| MEOX1 | mesenchyme homeobox 1 | 0.801 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.800 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.780 | |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.773 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.734 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.692 | |
| LILRA2 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2 | 0.681 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.640 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.619 | |
| HLA-A | major histocompatibility complex, class I, A | 0.618 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.596 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.588 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.580 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.562 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.561 | |
| HK3 | hexokinase 3 (white cell) | 0.559 | |
| EPOR | erythropoietin receptor | 0.538 | |
| HLA-B | major histocompatibility complex, class I, B | 0.487 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.477 | |
| BCL2A1 | BCL2-related protein A1 | 0.415 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.393 | |
| TYMP | thymidine phosphorylase | 0.371 | |
| PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.318 | |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 0.300 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.286 | |
| GNLY | granulysin | 0.273 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.247 | |
| NLRP3 | NLR family, pyrin domain containing 3 | 0.242 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.236 | |
| PRDM1 | PR domain containing 1, with ZNF domain | 0.225 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.220 | |
| AOAH | acyloxyacyl hydrolase (neutrophil) | 0.208 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.201 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.197 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.185 | |
| FPR3 | formyl peptide receptor 3 | 0.181 | |
| IL1RN | interleukin 1 receptor antagonist | 0.180 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.171 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.171 | |
| RGS1 | regulator of G-protein signaling 1 | 0.170 | |
| IL10 | interleukin 10 | 0.166 | |
| IL7R | interleukin 7 receptor | 0.161 | |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.159 | |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.142 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.141 | |
| IFNG | interferon, gamma | 0.138 | |
| CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.138 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.135 | |
| TNF | tumor necrosis factor | 0.134 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.133 | |
| SELE | selectin E | 0.131 | |
| LILRA3 | leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3 | 0.129 | |
| IL15RA | interleukin 15 receptor, alpha | 0.125 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.124 | |
| LILRB4 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 | 0.119 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.115 | |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.112 | |
| NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.110 | |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.105 | |
| GATA4 | GATA binding protein 4 | 0.105 | |
| HLA-G | major histocompatibility complex, class I, G | 0.103 | |
| CH25H | cholesterol 25-hydroxylase | 0.102 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.102 | |
| CD83 | CD83 molecule | 0.101 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.099 | |
| SLAMF7 | SLAM family member 7 | 0.098 | |
| BATF | basic leucine zipper transcription factor, ATF-like | 0.093 | |
| TBX21 | T-box 21 | 0.089 | |
| SIRPB1 | signal-regulatory protein beta 1 | 0.088 | |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.088 | |
| TBX5 | T-box 5 | 0.088 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.088 | |
| CCL23 | chemokine (C-C motif) ligand 23 | 0.086 | |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.083 | |
| MSC | musculin | 0.081 | |
| XCL2 | chemokine (C motif) ligand 2 | 0.080 | |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.078 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.078 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.076 | |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.075 | |
| TAP1 | transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) | 0.071 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.068 | |
| C2 | complement component 2 | 0.066 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.066 | |
| CD33 | CD33 molecule | 0.064 | |
| TMSB4X | thymosin beta 4, X-linked | 0.063 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Bcl2l11 | BCL2-like 11 (apoptosis facilitator) | 0.740 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.453 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.180 | |
| Stat2 | signal transducer and activator of transcription 2 | 0.121 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.095 | |
| Hoxa1 | homeobox A1 | 0.095 | |
| Bak1 | BCL2-antagonist/killer 1 | 0.053 | |
| Igh | immunoglobulin heavy chain complex | 0.045 | |
| Il27ra | interleukin 27 receptor, alpha | 0.041 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.037 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.035 | |
| Cd19 | CD19 antigen | 0.030 | |
| Bax | BCL2-associated X protein | 0.030 | |
| Wt1 | Wilms tumor 1 homolog | 0.029 | |
| Tbx3 | T-box 3 | 0.029 | |
| Sfpi1 | SFFV proviral integration 1 | 0.028 | |
| Stat5b | signal transducer and activator of transcription 5B | 0.027 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.026 | |
| Stat5a | signal transducer and activator of transcription 5A | 0.026 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.021 | |
| Socs1 | suppressor of cytokine signaling 1 | 0.019 | |
| Fgf10 | fibroblast growth factor 10 | 0.018 | |
| Tbx5 | T-box 5 | 0.018 | |
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.016 | |
| Jag1 | jagged 1 | 0.015 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.015 | |
| 1810019J16Rik | RIKEN cDNA 1810019J16 gene | 0.015 | |
| Trp63 | transformation related protein 63 | 0.014 | |
| Foxg1 | forkhead box G1 | 0.013 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.013 | |
| Trp53 | transformation related protein 53 | 0.013 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.013 | |
| Irf4 | interferon regulatory factor 4 | 0.013 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.012 | |
| Ttc7 | tetratricopeptide repeat domain 7 | 0.012 | |
| Ikzf1 | IKAROS family zinc finger 1 | 0.012 | |
| Wnt9b | wingless-type MMTV integration site 9B | 0.012 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.012 | |
| Bbc3 | BCL2 binding component 3 | 0.011 | |
| Irf8 | interferon regulatory factor 8 | 0.011 | |
| Prf1 | perforin 1 (pore forming protein) | 0.011 | |
| Mcl1 | myeloid cell leukemia sequence 1 | 0.011 | |
| Rnf2 | ring finger protein 2 | 0.011 | |
| Nfkb2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 | 0.011 | |
| Tcrb | T-cell receptor beta chain | 0.010 | |
| Tcrd | T-cell receptor delta chain | 0.010 | |
| Bcl6 | B-cell leukemia/lymphoma 6 | 0.010 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.010 |