The network for 'regulation of leukocyte chemotaxis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte chemotaxis

Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.

Homo sapiens
Name Description Probability Func Analog Organism
CCR5 chemokine (C-C motif) receptor 5 1.000
FYN FYN oncogene related to SRC, FGR, YES 0.995
CXCL9 chemokine (C-X-C motif) ligand 9 0.995
CCL5 chemokine (C-C motif) ligand 5 0.986
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.977
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.975
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.970
CCL4 chemokine (C-C motif) ligand 4 0.929
CXCL10 chemokine (C-X-C motif) ligand 10 0.925
S100B S100 calcium binding protein B 0.909
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.889
CCR7 chemokine (C-C motif) receptor 7 0.883
CCL19 chemokine (C-C motif) ligand 19 0.880
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.878
IFNG interferon, gamma 0.862
CCL22 chemokine (C-C motif) ligand 22 0.855
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.852
S100A1 S100 calcium binding protein A1 0.848
VEGFA vascular endothelial growth factor A 0.830
AXL AXL receptor tyrosine kinase 0.828
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.810
S100A16 S100 calcium binding protein A16 0.809
CD2 CD2 molecule 0.785
NRP1 neuropilin 1 0.784
S100A14 S100 calcium binding protein A14 0.776
DPP4 dipeptidyl-peptidase 4 0.757
IL8 interleukin 8 0.755
CXCL11 chemokine (C-X-C motif) ligand 11 0.736
FN1 fibronectin 1 0.707
CCL8 chemokine (C-C motif) ligand 8 0.691
CCL2 chemokine (C-C motif) ligand 2 0.686
PDIA3 protein disulfide isomerase family A, member 3 0.684
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.629
CXCL13 chemokine (C-X-C motif) ligand 13 0.628
CXCR4 chemokine (C-X-C motif) receptor 4 0.614
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.567
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.559
PLAUR plasminogen activator, urokinase receptor 0.558
CCL13 chemokine (C-C motif) ligand 13 0.557
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.551
ABI2 abl-interactor 2 0.534
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.520
PLAT plasminogen activator, tissue 0.515
CCR1 chemokine (C-C motif) receptor 1 0.487
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.484
COL1A1 collagen, type I, alpha 1 0.463
S100A6 S100 calcium binding protein A6 0.446
TGM2 transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) 0.424
IL2RG interleukin 2 receptor, gamma 0.411
IL10 interleukin 10 0.407
IL2RB interleukin 2 receptor, beta 0.401
IL6 interleukin 6 (interferon, beta 2) 0.391
FYB FYN binding protein 0.371
CXCL2 chemokine (C-X-C motif) ligand 2 0.364
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.354
CCR2 chemokine (C-C motif) receptor 2 0.346
ADAM9 ADAM metallopeptidase domain 9 0.342
CCL11 chemokine (C-C motif) ligand 11 0.321
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.319
PLAU plasminogen activator, urokinase 0.315
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.298
IL7R interleukin 7 receptor 0.297
CCL7 chemokine (C-C motif) ligand 7 0.282
CCR4 chemokine (C-C motif) receptor 4 0.274
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.256
VCAM1 vascular cell adhesion molecule 1 0.252
NCF1 neutrophil cytosolic factor 1 0.250
NCF2 neutrophil cytosolic factor 2 0.248
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.243
COL4A1 collagen, type IV, alpha 1 0.234
COL5A1 collagen, type V, alpha 1 0.231
CCL3 chemokine (C-C motif) ligand 3 0.230
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.228
SNX33 sorting nexin 33 0.205
THBS1 thrombospondin 1 0.205
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.193
CXCL3 chemokine (C-X-C motif) ligand 3 0.191
APOE apolipoprotein E 0.190
S100A9 S100 calcium binding protein A9 0.188
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.182
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 0.179
JAM2 junctional adhesion molecule 2 0.170
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.166
CXCR6 chemokine (C-X-C motif) receptor 6 0.159
EZR ezrin 0.158
RGS1 regulator of G-protein signaling 1 0.152
LTBP2 latent transforming growth factor beta binding protein 2 0.152
CCL20 chemokine (C-C motif) ligand 20 0.151
IRF4 interferon regulatory factor 4 0.150
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.150
FPR3 formyl peptide receptor 3 0.146
BCL2A1 BCL2-related protein A1 0.146
COL4A2 collagen, type IV, alpha 2 0.144
C2 complement component 2 0.144
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.141
IGFBP5 insulin-like growth factor binding protein 5 0.141
COL1A2 collagen, type I, alpha 2 0.140
COL3A1 collagen, type III, alpha 1 0.137
TNF tumor necrosis factor 0.136
TSC22D4 TSC22 domain family, member 4 0.134
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
cdh5 cadherin 5 0.069
csf1ra colony stimulating factor 1 receptor, a 0.041
tie2 endothelium-specific receptor tyrosine kinase 2 0.037
plxnd1 plexin D1 0.029
kdrl kinase insert domain receptor like 0.025
myf5 myogenic factor 5 0.024
kdr kinase insert domain receptor (a type III receptor tyrosine kinase) 0.021
si:ch211-212m21.5 si:ch211-212m21.5 0.020
sox10 SRY-box containing gene 10 0.020
tie1 endothelium-specific receptor tyrosine kinase 1 0.019
dlc deltaC 0.019
vegfc vascular endothelial growth factor c 0.017
dll4 delta-like 4 (Drosophila) 0.016
nod1 nucleotide-binding oligomerization domain containing 1 0.016
dzip1 DAZ interacting protein 1 0.016
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.014
etv2 ets variant gene 2 0.014
jam2a junctional adhesion molecule 2a 0.014
nrp2b neuropilin 2b 0.014
osr1 odd-skipped related 1 (Drosophila) 0.013
krml2.2 Kreisler (mouse) maf-related leucine zipper homolog 2.2 0.013
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.013
spns2 spinster homolog 2 (Drosophila) 0.012
itga5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.012
LOC557072 caspase recruitment domain-containing protein 11-like 0.011
s1pr2 sphingosine-1-phosphate receptor 2 0.010
slc30a7 solute carrier family 30 (zinc transporter), member 7 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cxcl10 chemokine (C-X-C motif) ligand 10 0.859
Ctss cathepsin S 0.750
Ccl2 chemokine (C-C motif) ligand 2 0.738
Il1b interleukin 1 beta 0.543
Cxcl2 chemokine (C-X-C motif) ligand 2 0.506
Ccl4 chemokine (C-C motif) ligand 4 0.454
Il6 interleukin 6 0.440
Cd14 CD14 molecule 0.302
RT1-Ba RT1 class II, locus Ba 0.276
Tyrobp Tyro protein tyrosine kinase binding protein 0.234
Il1a interleukin 1 alpha 0.223
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.170
Ccl3 chemokine (C-C motif) ligand 3 0.168
RT1-Db1 RT1 class II, locus Db1 0.122
Hck hemopoietic cell kinase 0.122
Ccl20 chemokine (C-C motif) ligand 20 0.097
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.094
Fcn1 ficolin (collagen/fibrinogen domain containing) 1 0.085
Lyz2 lysozyme 2 0.076
Ccl7 chemokine (C-C motif) ligand 7 0.072
P2ry6 pyrimidinergic receptor P2Y, G-protein coupled, 6 0.068
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.068
Fosl1 fos-like antigen 1 0.064
Fgfr2 fibroblast growth factor receptor 2 0.063
Cd68 Cd68 molecule 0.055
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.050
Cd53 Cd53 molecule 0.046
Ier3 immediate early response 3 0.045
Igsf6 immunoglobulin superfamily, member 6 0.041
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.038
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.036
Tcrb T-cell receptor beta chain 0.035
RT1-Da RT1 class II, locus Da 0.034
Dio2 deiodinase, iodothyronine, type II 0.033
Olr1500 olfactory receptor 1500 0.033
Edn1 endothelin 1 0.032
Il2rg interleukin 2 receptor, gamma 0.032
Cd83 CD83 molecule 0.030
Tgm1 transglutaminase 1, K polypeptide 0.030
Ccr2 chemokine (C-C motif) receptor 2 0.029
C5ar1 complement component 5a receptor 1 0.028
Sell selectin L 0.026
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.025
Il2rb interleukin 2 receptor, beta 0.025
Il8rb interleukin 8 receptor, beta 0.025
Icam1 intercellular adhesion molecule 1 0.025
Ccr5 chemokine (C-C motif) receptor 5 0.025
Plek pleckstrin 0.023
Bcl2a1d B-cell leukemia/lymphoma 2 related protein A1d 0.023
Rab20 RAB20, member RAS oncogene family 0.023
Ptgs2 prostaglandin-endoperoxide synthase 2 0.023
Gzmk granzyme K 0.023
Socs3 suppressor of cytokine signaling 3 0.023
Laptm5 lysosomal protein transmembrane 5 0.022
Cpa3 carboxypeptidase A3, mast cell 0.022
Igfbp5 insulin-like growth factor binding protein 5 0.021
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.021
Rgs1 regulator of G-protein signaling 1 0.020
Neurl3 neuralized homolog 3 (Drosophila) 0.020
Il1rn interleukin 1 receptor antagonist 0.019
Cd86 CD86 molecule 0.019
Mmp3 matrix metallopeptidase 3 0.018
C1qc complement component 1, q subcomponent, C chain 0.018
Gzmb granzyme B 0.018
Calcrl calcitonin receptor-like 0.018
Sele selectin E 0.018
Plau plasminogen activator, urokinase 0.018
Cd37 CD37 molecule 0.017
Nkg7 natural killer cell group 7 sequence 0.017
Ccr3 chemokine (C-C motif) receptor 3 0.017
Iapp islet amyloid polypeptide 0.017
Adam2 ADAM metallopeptidase domain 2 0.016
Reg3g regenerating islet-derived 3 gamma 0.016
Fcer1g Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.016
Gpr83 G protein-coupled receptor 83 0.016
Cxcl11 chemokine (C-X-C motif) ligand 11 0.016
Pla2g2a phospholipase A2, group IIA (platelets, synovial fluid) 0.015
Syn1 synapsin I 0.015
Rhoj ras homolog gene family, member J 0.015
P2ry14 purinergic receptor P2Y, G-protein coupled, 14 0.015
Cd4 Cd4 molecule 0.015
Xcl1 chemokine (C motif) ligand 1 0.015
Fcgr3a Fc fragment of IgG, low affinity IIIa, receptor 0.015
F2rl2 coagulation factor II (thrombin) receptor-like 2 0.014
Ptprc protein tyrosine phosphatase, receptor type, C 0.014
Tfpi2 tissue factor pathway inhibitor 2 0.014
C1qa complement component 1, q subcomponent, A chain 0.014
Lst1 leukocyte specific transcript 1 0.014
Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 0.013
Cd69 Cd69 molecule 0.013
Sftpa1 surfactant protein A1 0.013
Serpinb2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 0.013
Ifit3 interferon-induced protein with tetratricopeptide repeats 3 0.013
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.013
Mapk1 mitogen activated protein kinase 1 0.013
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.012
Mmp12 matrix metallopeptidase 12 0.012
Thbd thrombomodulin 0.012
Cd200r1 CD200 receptor 1 0.012
Prkcg protein kinase C, gamma 0.012
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism