Process View
The network for 'regulation of chemokine mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
CCL4 | chemokine (C-C motif) ligand 4 | 0.992 | |
CCL2 | chemokine (C-C motif) ligand 2 | 0.970 | |
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.965 | |
IL8 | interleukin 8 | 0.942 | |
CCL8 | chemokine (C-C motif) ligand 8 | 0.905 | |
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.870 | |
CCL5 | chemokine (C-C motif) ligand 5 | 0.847 | |
IL1B | interleukin 1, beta | 0.835 | |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.802 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.760 | |
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.624 | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.623 | |
IL6 | interleukin 6 (interferon, beta 2) | 0.524 | |
CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.514 | |
CCL13 | chemokine (C-C motif) ligand 13 | 0.512 | |
IDE | insulin-degrading enzyme | 0.449 | |
CCR1 | chemokine (C-C motif) receptor 1 | 0.390 | |
ICAM1 | intercellular adhesion molecule 1 | 0.274 | |
DPP4 | dipeptidyl-peptidase 4 | 0.194 | |
CCL3 | chemokine (C-C motif) ligand 3 | 0.180 | |
RGS1 | regulator of G-protein signaling 1 | 0.178 | |
IFNG | interferon, gamma | 0.173 | |
SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.130 | |
CPE | carboxypeptidase E | 0.119 | |
CCL19 | chemokine (C-C motif) ligand 19 | 0.116 | |
CCR7 | chemokine (C-C motif) receptor 7 | 0.101 | |
CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.092 | |
CD83 | CD83 molecule | 0.088 | |
CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.087 | |
CCL22 | chemokine (C-C motif) ligand 22 | 0.081 | |
IL2RB | interleukin 2 receptor, beta | 0.078 | |
GNLY | granulysin | 0.069 | |
IL10 | interleukin 10 | 0.068 | |
VCAM1 | vascular cell adhesion molecule 1 | 0.066 | |
CCL7 | chemokine (C-C motif) ligand 7 | 0.066 | |
CCL21 | chemokine (C-C motif) ligand 21 | 0.059 | |
SLAMF8 | SLAM family member 8 | 0.056 | |
TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.055 | |
C1QA | complement component 1, q subcomponent, A chain | 0.055 | |
SELE | selectin E | 0.047 | |
HLA-DPB1 | major histocompatibility complex, class II, DP beta 1 | 0.045 | |
CCL20 | chemokine (C-C motif) ligand 20 | 0.042 | |
CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.041 | |
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.038 | |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.037 | |
MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.036 | |
C1QB | complement component 1, q subcomponent, B chain | 0.035 | |
GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.033 | |
UBD | ubiquitin D | 0.033 | |
FPR3 | formyl peptide receptor 3 | 0.032 | |
IL1RN | interleukin 1 receptor antagonist | 0.029 | |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.029 | |
RDH11 | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 0.028 | |
DARC | Duffy blood group, chemokine receptor | 0.028 | |
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.028 | |
BCL2A1 | BCL2-related protein A1 | 0.027 | |
TNF | tumor necrosis factor | 0.026 | |
CCL11 | chemokine (C-C motif) ligand 11 | 0.026 | |
IL10RA | interleukin 10 receptor, alpha | 0.025 | |
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.024 | |
HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.024 | |
PLEK | pleckstrin | 0.024 | |
LAMP3 | lysosomal-associated membrane protein 3 | 0.023 | |
ADAMDEC1 | ADAM-like, decysin 1 | 0.022 | |
IDO1 | indoleamine 2,3-dioxygenase 1 | 0.021 | |
PRF1 | perforin 1 (pore forming protein) | 0.020 | |
CCR4 | chemokine (C-C motif) receptor 4 | 0.018 | |
HLA-DRB5 | major histocompatibility complex, class II, DR beta 5 | 0.018 | |
NKG7 | natural killer cell group 7 sequence | 0.017 | |
IL7R | interleukin 7 receptor | 0.017 | |
KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.017 | |
SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.016 | |
MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.015 | |
PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.015 | |
IL18RAP | interleukin 18 receptor accessory protein | 0.015 | |
SLAMF7 | SLAM family member 7 | 0.015 | |
C2 | complement component 2 | 0.014 | |
INHBA | inhibin, beta A | 0.014 | |
CD163 | CD163 molecule | 0.013 | |
IL32 | interleukin 32 | 0.013 | |
STAT4 | signal transducer and activator of transcription 4 | 0.012 | |
CH25H | cholesterol 25-hydroxylase | 0.012 | |
KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.012 | |
DPT | dermatopontin | 0.012 | |
CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.012 | |
CD86 | CD86 molecule | 0.011 | |
C1QC | complement component 1, q subcomponent, C chain | 0.011 | |
OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.011 | |
MARCO | macrophage receptor with collagenous structure | 0.011 |