The network for 'actin filament polymerization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

actin filament polymerization

Assembly of actin filaments by the addition of actin monomers to a filament.

Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
GRB2 growth factor receptor-bound protein 2 1.000
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.999
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.996
GAS7 growth arrest-specific 7 0.995
ACTR3 ARP3 actin-related protein 3 homolog (yeast) 0.991
IQGAP1 IQ motif containing GTPase activating protein 1 0.988
BAIAP2 BAI1-associated protein 2 0.986
FYN FYN oncogene related to SRC, FGR, YES 0.986
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.985
ABI1 abl-interactor 1 0.981
VAV1 vav 1 guanine nucleotide exchange factor 0.979
ACTR2 ARP2 actin-related protein 2 homolog (yeast) 0.978
ARPC2 actin related protein 2/3 complex, subunit 2, 34kDa 0.966
ITSN1 intersectin 1 (SH3 domain protein) 0.962
WASL Wiskott-Aldrich syndrome-like 0.936
ARPC5 actin related protein 2/3 complex, subunit 5, 16kDa 0.933
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.924
TRIP10 thyroid hormone receptor interactor 10 0.898
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.892
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.886
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.880
CTTN cortactin 0.856
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.854
HCK hemopoietic cell kinase 0.834
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.790
BCAR1 breast cancer anti-estrogen resistance 1 0.789
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa 0.770
ACTN1 actinin, alpha 1 0.765
ZYX zyxin 0.733
FLNA filamin A, alpha 0.730
NCK1 NCK adaptor protein 1 0.725
SPTAN1 spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) 0.724
TPM4 tropomyosin 4 0.717
PFN1 profilin 1 0.687
LCK lymphocyte-specific protein tyrosine kinase 0.674
NCKAP1 NCK-associated protein 1 0.617
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.603
FASLG Fas ligand (TNF superfamily, member 6) 0.561
CCR5 chemokine (C-C motif) receptor 5 0.559
SH3BP2 SH3-domain binding protein 2 0.557
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.545
DAAM1 dishevelled associated activator of morphogenesis 1 0.543
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.541
CORO1C coronin, actin binding protein, 1C 0.536
TNK2 tyrosine kinase, non-receptor, 2 0.532
FNBP1L formin binding protein 1-like 0.520
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.515
EPS8 epidermal growth factor receptor pathway substrate 8 0.512
NCF2 neutrophil cytosolic factor 2 0.478
WASF1 WAS protein family, member 1 0.465
MED15 mediator complex subunit 15 0.464
PTK2 PTK2 protein tyrosine kinase 2 0.436
WIPF1 WAS/WASL interacting protein family, member 1 0.435
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.433
SH3KBP1 SH3-domain kinase binding protein 1 0.424
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.381
PTPN23 protein tyrosine phosphatase, non-receptor type 23 0.380
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.371
MYPN myopalladin 0.369
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.365
PRKCA protein kinase C, alpha 0.357
CAPZB capping protein (actin filament) muscle Z-line, beta 0.341
MYH9 myosin, heavy chain 9, non-muscle 0.332
BLNK B-cell linker 0.331
FKBP1A FK506 binding protein 1A, 12kDa 0.328
SH2D4A SH2 domain containing 4A 0.322
ABI2 abl-interactor 2 0.321
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.316
CCL4 chemokine (C-C motif) ligand 4 0.314
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.308
CD2AP CD2-associated protein 0.301
NCOA1 nuclear receptor coactivator 1 0.300
ARFIP2 ADP-ribosylation factor interacting protein 2 0.297
SH3BGRL3 SH3 domain binding glutamic acid-rich protein like 3 0.290
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.268
PDLIM7 PDZ and LIM domain 7 (enigma) 0.259
C3orf15 chromosome 3 open reading frame 15 0.252
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.231
ARHGAP1 Rho GTPase activating protein 1 0.215
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.214
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.212
LRRK2 leucine-rich repeat kinase 2 0.205
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.203
TJP1 tight junction protein 1 (zona occludens 1) 0.202
SOS1 son of sevenless homolog 1 (Drosophila) 0.201
NCKIPSD NCK interacting protein with SH3 domain 0.198
RAB1A RAB1A, member RAS oncogene family 0.197
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.197
CAPNS1 calpain, small subunit 1 0.194
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.193
CYFIP2 cytoplasmic FMR1 interacting protein 2 0.190
PICALM phosphatidylinositol binding clathrin assembly protein 0.182
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.179
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.173
FNBP1 formin binding protein 1 0.168
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.167
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.166
WASF2 WAS protein family, member 2 0.164
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
cotl1 coactosin-like 1 (Dictyostelium) 0.862
arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.750
csf3r colony stimulating factor 3 receptor (granulocyte) 0.401
cfl1 cofilin 1 (non-muscle) 0.347
arpc5b actin related protein 2/3 complex, subunit 5B 0.296
cldni claudin i 0.232
wasb Wiskott-Aldrich syndrome (eczema-thrombocytopenia) b 0.231
me2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.184
cdc42 cell division cycle 42 0.182
rab5c RAB5C, member RAS oncogene family 0.175
wasa Wiskott-Aldrich syndrome (eczema-thrombocytopenia) a 0.167
rc3 rabconnectin 3 0.157
arpc5a actin related protein 2/3 complex, subunit 5A 0.143
btk Bruton agammaglobulinemia tyrosine kinase 0.136
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.133
sept8a septin 8a 0.127
slc25a25a solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25a 0.123
caspa caspase a 0.122
zgc:153867 zgc:153867 0.120
cltca clathrin, heavy polypeptide a (Hc) 0.120
gmfg glia maturation factor, gamma 0.118
plxnb2a plexin b2a 0.111
myl9l myosin, light polypeptide 9, like 0.110
ppm1aa protein phosphatase, Mg2+/Mn2+ dependent, 1Aa 0.110
zgc:195154 zgc:195154 0.109
colec11 collectin sub-family member 11 0.108
fli1b friend leukemia integration 1b 0.108
arpc1a actin related protein 2/3 complex, subunit 1A 0.104
npsn nephrosin 0.099
zgc:91930 zgc:91930 0.099
si:dkey-204a24.2 si:dkey-204a24.2 0.099
zgc:92360 zgc:92360 0.097
smyhc1 slow myosin heavy chain 1 0.095
zgc:66317 zgc:66317 0.092
myd88 myeloid differentiation primary response gene (88) 0.089
si:ch211-232m7.1 si:ch211-232m7.1 0.089
sept6 septin 6 0.089
calm3b calmodulin 3b (phosphorylase kinase, delta) 0.088
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.088
vegfab vascular endothelial growth factor Ab 0.085
msna moesin a 0.085
wdr1 WD repeat domain 1 0.084
copg2 coatomer protein complex, subunit gamma 2 0.084
ptprc protein tyrosine phosphatase, receptor type, C 0.084
actr3 ARP3 actin-related protein 3 homolog (yeast) 0.083
slc4a1a solute carrier family 4, anion exchanger, member 1a 0.083
metap2 methionyl aminopeptidase 2 0.083
ppial peptidylprolyl isomerase A, like 0.082
mfn2 mitofusin 2 0.081
pi4kb phosphatidylinositol 4-kinase, catalytic, beta 0.081
hist1h4l histone 1, H4, like 0.081
lasp1 LIM and SH3 protein 1 0.081
pknox1.2 pbx/knotted 1 homeobox 1.2 0.080
znf609 zinc finger protein 609 0.079
hoxa11b homeo box A11b 0.079
klfd Kruppel-like factor d 0.079
rhoab ras homolog gene family, member Ab 0.079
zc4h2 zinc finger, C4H2 domain containing 0.077
actr2 ARP2 actin-related protein 2 homolog 0.077
ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.076
twf1a twinfilin, actin-binding protein, homolog 1a 0.076
nbl1 neuroblastoma, suppression of tumorigenicity 1 0.075
akt2 v-akt murine thymoma viral oncogene homolog 2 0.075
flot1b flotillin 1b 0.075
zgc:171553 zgc:171553 0.075
ehd1 EH-domain containing 1 0.073
lyz lysozyme 0.073
LOC100151049 lysosomal-associated protein transmembrane 5 0.072
zgc:63587 zgc:63587 0.072
ube2i2 ubiquitin-conjugating enzyme E2I2 0.071
sept2 septin 2 0.071
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.070
cyt1 type I cytokeratin, enveloping layer 0.070
gsk3b glycogen synthase kinase 3 beta 0.070
capzb capping protein (actin filament) muscle Z-line, beta 0.069
bmp5 bone morphogenetic protein 5 0.068
nptna neuroplastin a 0.067
snx12 sorting nexin 12 0.067
praf2 PRA1 domain family, member 2 0.067
mmp9 matrix metalloproteinase 9 0.066
zgc:112018 zgc:112018 0.066
col6a6 collagen, type VI, alpha 6 0.066
acsbg2 acyl-CoA synthetase bubblegum family member 2 0.065
fkbp1aa FK506 binding protein 1Aa 0.065
appl1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.064
smad9 MAD homolog 9 (Drosophila) 0.063
nphs2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.063
cd99l2 CD99 antigen-like 2 0.063
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.062
atp6v1al ATPase, H+ transporting, lysosomal V1 subunit A, like 0.061
tubb5 tubulin, beta 5 0.061
tpm1 tropomyosin 1 (alpha) 0.060
stau2 staufen, RNA binding protein, homolog 2 (Drosophila) 0.060
cxcr3.2 chemokine (C-X-C motif) receptor 3.2 0.059
zbtb4 zinc finger and BTB domain containing 4 0.059
arpc4l actin related protein 2/3 complex, subunit 4, like 0.059
galnt7 UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 7 0.058
spry2 sprouty homolog 2 0.058
cbfb core-binding factor, beta subunit 0.058
cmpk cytidylate kinase 0.058
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Drosophila melanogaster
Name Description Probability Func Analog Organism
chic chickadee 0.983
p120ctn Adherens junction protein p120 0.873
mbc myoblast city 0.812
Arp66B Actin-related protein 66B 0.785
Vrp1 Verprolin 1 0.734
ena enabled 0.695
Rac1 CG2248 gene product from transcript CG2248-RA 0.670
katanin-60 katanin 60 0.648
Hem HEM-protein 0.620
bif bifocal 0.611
Abi Abelson interacting protein 0.571
cta concertina 0.564
cpb capping protein beta 0.562
WASp CG1520 gene product from transcript CG1520-RA 0.527
Rho1 CG8416 gene product from transcript CG8416-RB 0.492
par-1 CG8201 gene product from transcript CG8201-RA 0.447
spas spastin 0.439
Arc-p34 CG10954 gene product from transcript CG10954-RA 0.406
gig gigas 0.385
Cortactin CG3637 gene product from transcript CG3637-RA 0.375
cpa capping protein alpha 0.351
Pak PAK-kinase 0.348
robo roundabout 0.329
Rala Ras-related protein 0.317
Rab11 Rab-protein 11 0.313
twf twinfilin 0.301
baz bazooka 0.295
rok Rho-kinase 0.288
trc tricornered 0.268
CkIIbeta Casein kinase II beta subunit 0.266
RhoGAP93B CG3421 gene product from transcript CG3421-RA 0.241
plexA plexin A 0.225
Cdc42 CG12530 gene product from transcript CG12530-RA 0.216
trio CG18214 gene product from transcript CG18214-RA 0.207
X11L CG5675 gene product from transcript CG5675-RB 0.206
msn misshapen 0.205
cindr CIN85 and CD2AP orthologue 0.196
Sop2 Suppressor of profilin 2 0.190
Sos Son of sevenless 0.189
par-6 CG5884 gene product from transcript CG5884-RA 0.179
sls sallimus 0.177
Arp14D Actin-related protein 14D 0.167
Mtl Mig-2-like 0.164
Akt1 CG4006 gene product from transcript CG4006-RA 0.159
Btk29A Btk family kinase at 29A 0.158
usp ultraspiracle 0.154
sqh spaghetti squash 0.151
Sra-1 specifically Rac1-associated protein 1 0.150
Pkn Protein kinase related to protein kinase N 0.150
BicD Bicaudal D 0.149
Dcr-2 Dicer-2 0.132
Arf51F ADP ribosylation factor 51F 0.132
CG8578 CG8578 gene product from transcript CG8578-RA 0.130
G-oalpha47A G protein oalpha 47A 0.129
spir spire 0.128
Mical Molecule interacting with CasL 0.115
flr flare 0.115
cora coracle 0.106
rap retina aberrant in pattern 0.100
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.098
Pten CG5671 gene product from transcript CG5671-RB 0.096
wdb widerborst 0.095
Lasp CG3849 gene product from transcript CG3849-RB 0.094
RhoGEF2 CG9635 gene product from transcript CG9635-RF 0.092
rst roughest 0.090
lqfR liquid facets-Related 0.089
Eph Eph receptor tyrosine kinase 0.087
S6k RPS6-p70-protein kinase 0.085
Ptp69D Protein tyrosine phosphatase 69D 0.085
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.084
drpr draper 0.082
stai stathmin 0.082
kuz kuzbanian 0.082
shot short stop 0.081
Ephrin CG1862 gene product from transcript CG1862-RA 0.080
Chc Clathrin heavy chain 0.080
drk downstream of receptor kinase 0.080
otk off-track 0.077
alpha-Spec alpha Spectrin 0.075
ttk tramtrack 0.072
egl egalitarian 0.070
CG11299 CG11299 gene product from transcript CG11299-RA 0.070
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.069
zip zipper 0.069
rin rasputin 0.066
didum dilute class unconventional myosin 0.064
cnc cap-n-collar 0.064
Mrtf Myocardin-related transcription factor 0.063
Fak56D Focal Adhesion Kinase 0.062
Shc SHC-adaptor protein 0.061
DAAM Dishevelled Associated Activator of Morphogenesis 0.061
capu cappuccino 0.060
vav CG7893 gene product from transcript CG7893-RB 0.060
egh egghead 0.059
Tak1 TGF-beta activated kinase 1 0.059
fra frazzled 0.058
Dad Daughters against dpp 0.058
srp serpent 0.055
futsch CG34387 gene product from transcript CG34387-RC 0.055
shrb shrub 0.055
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Mus musculus
Name Description Probability Func Analog Organism
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 1.000
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.998
Wdr1 WD repeat domain 1 0.995
Vasp vasodilator-stimulated phosphoprotein 0.994
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.992
Arpc4 actin related protein 2/3 complex, subunit 4 0.986
Rac1 RAS-related C3 botulinum substrate 1 0.972
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.969
Cttn cortactin 0.967
Capzb capping protein (actin filament) muscle Z-line, beta 0.962
Abi1 abl-interactor 1 0.961
Ldb3 LIM domain binding 3 0.944
Actb actin, beta 0.921
Dnm1 dynamin 1 0.893
Mapkap1 mitogen-activated protein kinase associated protein 1 0.855
Cfl1 cofilin 1, non-muscle 0.855
Blnk B-cell linker 0.820
Efnb2 ephrin B2 0.819
Msn moesin 0.801
Enah enabled homolog (Drosophila) 0.763
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.733
Pfn1 profilin 1 0.723
Cltc clathrin, heavy polypeptide (Hc) 0.717
Actn4 actinin alpha 4 0.689
Tpm4 tropomyosin 4 0.671
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.655
Arhgap1 Rho GTPase activating protein 1 0.638
Actg1 actin, gamma, cytoplasmic 1 0.635
Prkce protein kinase C, epsilon 0.615
Rhog ras homolog gene family, member G 0.603
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.597
Prkcb protein kinase C, beta 0.595
Rhoa ras homolog gene family, member A 0.587
Akt1 thymoma viral proto-oncogene 1 0.566
Sh3gl2 SH3-domain GRB2-like 2 0.562
Rod1 ROD1 regulator of differentiation 1 (S. pombe) 0.549
Pfn2 profilin 2 0.533
Wipf1 WAS/WASL interacting protein family, member 1 0.520
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.512
Iqgap1 IQ motif containing GTPase activating protein 1 0.490
Slit3 slit homolog 3 (Drosophila) 0.489
Map4k1 mitogen-activated protein kinase kinase kinase kinase 1 0.473
Casp1 caspase 1 0.471
Myh9 myosin, heavy polypeptide 9, non-muscle 0.444
Gbp5 guanylate binding protein 5 0.443
Gnb1 guanine nucleotide binding protein (G protein), beta 1 0.432
Csrp1 cysteine and glycine-rich protein 1 0.410
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.406
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.392
Capns1 calpain, small subunit 1 0.385
Pstpip1 proline-serine-threonine phosphatase-interacting protein 1 0.379
Dlg4 discs, large homolog 4 (Drosophila) 0.373
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.369
Actn2 actinin alpha 2 0.369
Arpc2 actin related protein 2/3 complex, subunit 2 0.368
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.367
Cotl1 coactosin-like 1 (Dictyostelium) 0.344
Calm1 calmodulin 1 0.343
Hif1a hypoxia inducible factor 1, alpha subunit 0.340
Actn1 actinin, alpha 1 0.328
Src Rous sarcoma oncogene 0.325
Lrrk2 leucine-rich repeat kinase 2 0.318
Cdc42se1 CDC42 small effector 1 0.310
Dbnl drebrin-like 0.303
Nsf N-ethylmaleimide sensitive fusion protein 0.296
Cyfip2 cytoplasmic FMR1 interacting protein 2 0.291
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) 0.284
Shisa5 shisa homolog 5 (Xenopus laevis) 0.284
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.283
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.281
Lmnb1 lamin B1 0.276
Mobkl1b MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.260
Grb2 growth factor receptor bound protein 2 0.258
Nckap1 NCK-associated protein 1 0.253
Nrcam neuron-glia-CAM-related cell adhesion molecule 0.252
Sh3kbp1 SH3-domain kinase binding protein 1 0.248
Robo2 roundabout homolog 2 (Drosophila) 0.238
Capn1 calpain 1 0.234
Arhgdib Rho, GDP dissociation inhibitor (GDI) beta 0.231
Trim30d tripartite motif-containing 30D 0.229
Fermt3 fermitin family homolog 3 (Drosophila) 0.227
Sh3bgrl3 SH3 domain binding glutamic acid-rich protein-like 3 0.219
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.215
Tmod3 tropomodulin 3 0.209
Dlg3 discs, large homolog 3 (Drosophila) 0.206
Cbl Casitas B-lineage lymphoma 0.205
Trpv2 transient receptor potential cation channel, subfamily V, member 2 0.204
Prkcd protein kinase C, delta 0.204
F11r F11 receptor 0.203
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.201
Alox5ap arachidonate 5-lipoxygenase activating protein 0.199
Stat5a signal transducer and activator of transcription 5A 0.198
Tuba1a tubulin, alpha 1A 0.198
Adam10 a disintegrin and metallopeptidase domain 10 0.193
Mlst8 MTOR associated protein, LST8 homolog (S. cerevisiae) 0.192
Csk c-src tyrosine kinase 0.192
Fyn Fyn proto-oncogene 0.190
Rap1b RAS related protein 1b 0.188
Rasgrp1 RAS guanyl releasing protein 1 0.188
Dok2 docking protein 2 0.186
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Rattus norvegicus
Name Description Probability Func Analog Organism
Efhd2 EF-hand domain family, member D2 0.224
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.194
Pfn1 profilin 1 0.181
Arpc2 actin related protein 2/3 complex, subunit 2 0.133
Wdr1 WD repeat domain 1 0.100
Tpm3 tropomyosin 3, gamma 0.088
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.083
Rap1b RAP1B, member of RAS oncogene family 0.078
Arpc1b actin related protein 2/3 complex, subunit 1B 0.078
Tubb5 tubulin, beta 5 0.069
Ptprc protein tyrosine phosphatase, receptor type, C 0.045
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.043
Rhoa ras homolog gene family, member A 0.043
Myh9 myosin, heavy chain 9, non-muscle 0.042
Rac1 ras-related C3 botulinum toxin substrate 1 0.037
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.036
Actb actin, beta 0.032
Arf6 ADP-ribosylation factor 6 0.032
Acta2 smooth muscle alpha-actin 0.030
Myl9 myosin, light chain 9, regulatory 0.029
Sri sorcin 0.028
Cttn cortactin 0.027
Cfl1 cofilin 1, non-muscle 0.025
Pak2 p21 protein (Cdc42/Rac)-activated kinase 2 0.023
Stk17b serine/threonine kinase 17b 0.023
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.021
Jak2 Janus kinase 2 0.020
Gnb2 guanine nucleotide binding protein (G protein), beta polypeptide 2 0.019
Myo1g myosin IG 0.019
Mtpn myotrophin 0.019
Tpm4 tropomyosin 4 0.018
Actn1 actinin, alpha 1 0.018
Cdc42se1 CDC42 small effector 1 0.018
Anxa2 annexin A2 0.017
Clic1 chloride intracellular channel 1 0.016
Ripk3 receptor-interacting serine-threonine kinase 3 0.015
Psmb10 proteasome (prosome, macropain) subunit, beta type 10 0.015
Usf1 upstream transcription factor 1 0.014
Tmed2 transmembrane emp24 domain trafficking protein 2 0.014
Gmfg glia maturation factor, gamma 0.014
Coro1a coronin, actin binding protein 1A 0.014
Emp1 epithelial membrane protein 1 0.014
Ptma prothymosin alpha 0.014
Sirpa signal-regulatory protein alpha 0.014
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 0.013
Dstn destrin 0.013
Lcp1 lymphocyte cytosolic protein 1 0.013
Cast calpastatin 0.013
Lcp2 lymphocyte cytosolic protein 2 0.013
Itgb2 integrin, beta 2 0.013
Myh11 myosin, heavy chain 11, smooth muscle 0.013
Sept11 septin 11 0.013
Cd82 Cd82 molecule 0.012
Grk6 G protein-coupled receptor kinase 6 0.012
Irf5 interferon regulatory factor 5 0.012
Il18 interleukin 18 0.012
Cd180 CD180 molecule 0.012
Rab2a RAB2A, member RAS oncogene family 0.012
Tagln2 transgelin 2 0.012
Cd37 CD37 molecule 0.012
Dnm1 dynamin 1 0.012
Litaf lipopolysaccharide-induced TNF factor 0.012
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.012
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.011
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.011
Ap3s1 adaptor-related protein complex 3, sigma 1 subunit 0.011
Anxa11 annexin A11 0.011
Pcdhgc3 protocadherin gamma subfamily C, 3 0.011
Plek pleckstrin 0.011
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.011
Lmna lamin A 0.011
Actr2 ARP2 actin-related protein 2 homolog (yeast) 0.011
Arhgdia Rho GDP dissociation inhibitor (GDI) alpha 0.011
Capzb capping protein (actin filament) muscle Z-line, beta 0.010
Ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.010
Psmb8 proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) 0.010
Il17ra interleukin 17 receptor A 0.010
Dgkz diacylglycerol kinase zeta 0.010
Cd53 Cd53 molecule 0.010
M6pr mannose-6-phosphate receptor, cation dependent 0.010
Csnk1a1 casein kinase 1, alpha 1 0.010
Nsf N-ethylmaleimide-sensitive factor 0.010
Tagln transgelin 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
ABP1 Abp1p 0.985
MYO5 Myo5p 0.979
CAP2 Cap2p 0.953
ARC40 Arc40p 0.896
ARC19 Arc19p 0.881
SRV2 Srv2p 0.800
RVS167 Rvs167p 0.787
ARC15 Arc15p 0.758
ARC18 Arc18p 0.675
BBC1 Bbc1p 0.664
ARC35 Arc35p 0.647
LAS17 Las17p 0.628
ARP3 Arp3p 0.578
ARP2 Arp2p 0.519
SAC6 Sac6p 0.452
LSB1 Lsb1p 0.302
SLA1 Sla1p 0.293
SLA2 Sla2p 0.281
CAP1 Cap1p 0.276
BOI1 Boi1p 0.267
AIP1 Aip1p 0.219
RHO1 Rho1p 0.188
BCK1 Bck1p 0.173
ACT1 Act1p 0.170
VRP1 Vrp1p 0.167
BZZ1 Bzz1p 0.122
TPM1 Tpm1p 0.111
PFY1 Pfy1p 0.107
SPA2 Spa2p 0.079
CDC24 Cdc24p 0.065
BEM3 Bem3p 0.062
YPK1 Ypk1p 0.058
CDC55 Cdc55p 0.052
COF1 Cof1p 0.049
TWF1 Twf1p 0.042
PAN1 Pan1p 0.042
TCO89 Tco89p 0.040
SCP1 Scp1p 0.036
BUD6 Bud6p 0.034
GYL1 Gyl1p 0.030
AVO1 Avo1p 0.030
KOG1 Kog1p 0.030
YSC84 Ysc84p 0.028
GIC2 Gic2p 0.022
YMR315W hypothetical protein 0.022
BEM1 Bem1p 0.019
SRD1 Srd1p 0.017
ARE2 Are2p 0.017
AIM3 Aim3p 0.016
FIR1 Fir1p 0.016
RDI1 Rdi1p 0.016
ARG8 Arg8p 0.016
ERG9 Erg9p 0.015
BUD2 Bud2p 0.015
EDE1 Ede1p 0.015
CMD1 Cmd1p 0.015
ADH2 Adh2p 0.015
YIL151C hypothetical protein 0.015
YOL038C-A hypothetical protein 0.015
PIN3 Pin3p 0.015
STE5 Ste5p 0.015
PRS2 Prs2p 0.015
YER134C hypothetical protein 0.014
YLR162W hypothetical protein 0.014
LEU2 Leu2p 0.014
YLR264C-A hypothetical protein 0.014
BOI2 Boi2p 0.014
SUT1 Sut1p 0.014
RIB4 Rib4p 0.013
CUR1 Cur1p 0.013
INP52 Inp52p 0.013
SGE1 Sge1p 0.013
CUP1-1 Cup1-1p 0.013
SRO77 Sro77p 0.013
URA3 Ura3p 0.013
MF(ALPHA)2 Mf(alpha)2p 0.013
YPR1 Ypr1p 0.013
SKM1 Skm1p 0.013
PAR32 Par32p 0.013
BUL1 Bul1p 0.013
TOR1 Tor1p 0.012
NBP2 Nbp2p 0.012
ARP10 Arp10p 0.012
MER1 Mer1p 0.012
PEA2 Pea2p 0.012
YLR108C hypothetical protein 0.012
BEM4 Bem4p 0.012
BEM2 Bem2p 0.012
FMN1 Fmn1p 0.012
HXT3 Hxt3p 0.012
TSC11 Tsc11p 0.012
CBK1 Cbk1p 0.011
ARO10 Aro10p 0.011
BTN2 Btn2p 0.011
MF(ALPHA)1 Mf(alpha)1p 0.011
ZPS1 Zps1p 0.011
ATP6 Atp6p 0.011
YLR042C hypothetical protein 0.011
YGL015C hypothetical protein 0.011
YIR035C hypothetical protein 0.011