The network for 'positive regulation of alpha beta t cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of alpha beta t cell proliferation

Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.

Homo sapiens
Name Description Probability Func Analog Organism
LCK lymphocyte-specific protein tyrosine kinase 1.000
LAT linker for activation of T cells 1.000
CD247 CD247 molecule 1.000
SYK spleen tyrosine kinase 0.998
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.968
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.966
CCR5 chemokine (C-C motif) receptor 5 0.965
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.916
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) 0.891
CD3E CD3e molecule, epsilon (CD3-TCR complex) 0.874
CCL4 chemokine (C-C motif) ligand 4 0.856
VAV1 vav 1 guanine nucleotide exchange factor 0.801
IL8 interleukin 8 0.757
CXCL9 chemokine (C-X-C motif) ligand 9 0.728
CCL2 chemokine (C-C motif) ligand 2 0.689
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.637
IL23A interleukin 23, alpha subunit p19 0.530
CD2 CD2 molecule 0.490
CCL8 chemokine (C-C motif) ligand 8 0.478
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.453
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.424
CXCL2 chemokine (C-X-C motif) ligand 2 0.383
CCL5 chemokine (C-C motif) ligand 5 0.364
CXCL10 chemokine (C-X-C motif) ligand 10 0.286
IL1B interleukin 1, beta 0.249
DPP4 dipeptidyl-peptidase 4 0.249
CCR7 chemokine (C-C motif) receptor 7 0.230
TRAF1 TNF receptor-associated factor 1 0.223
CXCL3 chemokine (C-X-C motif) ligand 3 0.182
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.176
IL6 interleukin 6 (interferon, beta 2) 0.170
CXCL11 chemokine (C-X-C motif) ligand 11 0.161
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa 0.155
BIRC3 baculoviral IAP repeat containing 3 0.135
CCL22 chemokine (C-C motif) ligand 22 0.133
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.130
ICAM1 intercellular adhesion molecule 1 0.121
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.117
SH3BP2 SH3-domain binding protein 2 0.093
CD86 CD86 molecule 0.088
IL2RB interleukin 2 receptor, beta 0.087
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.079
GRAP2 GRB2-related adaptor protein 2 0.078
CD80 CD80 molecule 0.070
SH2D2A SH2 domain containing 2A 0.066
UBASH3B ubiquitin associated and SH3 domain containing B 0.065
IDE insulin-degrading enzyme 0.064
CXCL13 chemokine (C-X-C motif) ligand 13 0.063
PRKCQ protein kinase C, theta 0.058
IL10 interleukin 10 0.057
CCR1 chemokine (C-C motif) receptor 1 0.051
GRB2 growth factor receptor-bound protein 2 0.045
CD28 CD28 molecule 0.043
CCL3 chemokine (C-C motif) ligand 3 0.042
BLNK B-cell linker 0.042
CCL13 chemokine (C-C motif) ligand 13 0.036
CD3G CD3g molecule, gamma (CD3-TCR complex) 0.033
PTPRC protein tyrosine phosphatase, receptor type, C 0.031
SOD2 superoxide dismutase 2, mitochondrial 0.030
MMP12 matrix metallopeptidase 12 (macrophage elastase) 0.029
CCR4 chemokine (C-C motif) receptor 4 0.028
IFNG interferon, gamma 0.028
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide 0.028
CCL20 chemokine (C-C motif) ligand 20 0.028
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.027
VCAM1 vascular cell adhesion molecule 1 0.026
CD274 CD274 molecule 0.026
NAMPT nicotinamide phosphoribosyltransferase 0.026
CD6 CD6 molecule 0.024
IL7R interleukin 7 receptor 0.022
FGR Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog 0.021
CCL7 chemokine (C-C motif) ligand 7 0.019
CXCL5 chemokine (C-X-C motif) ligand 5 0.019
SH3KBP1 SH3-domain kinase binding protein 1 0.019
CD48 CD48 molecule 0.018
CPD carboxypeptidase D 0.016
SH2D1A SH2 domain containing 1A 0.016
SELE selectin E 0.015
SRGN serglycin 0.014
TRAT1 T cell receptor associated transmembrane adaptor 1 0.014
TOP3A topoisomerase (DNA) III alpha 0.014
RGS1 regulator of G-protein signaling 1 0.013
CCL19 chemokine (C-C motif) ligand 19 0.013
CXCL6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.013
IL12A interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) 0.012
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.012
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
Ccl2 chemokine (C-C motif) ligand 2 0.762
Fyn Fyn proto-oncogene 0.692
Batf basic leucine zipper transcription factor, ATF-like 0.668
Ccl3 chemokine (C-C motif) ligand 3 0.494
Klrg1 killer cell lectin-like receptor subfamily G, member 1 0.461
Pdcd1 programmed cell death 1 0.358
Cd3e CD3 antigen, epsilon polypeptide 0.318
Itk IL2-inducible T-cell kinase 0.314
Tnf tumor necrosis factor 0.286
Cxcl13 chemokine (C-X-C motif) ligand 13 0.273
Cd7 CD7 antigen 0.265
Cd44 CD44 antigen 0.236
Cd28 CD28 antigen 0.232
Icos inducible T-cell co-stimulator 0.229
Ccl4 chemokine (C-C motif) ligand 4 0.216
Tnfrsf9 tumor necrosis factor receptor superfamily, member 9 0.209
Sh2d2a SH2 domain protein 2A 0.195
Cd19 CD19 antigen 0.182
Ccl8 chemokine (C-C motif) ligand 8 0.178
Cd86 CD86 antigen 0.169
Ccr2 chemokine (C-C motif) receptor 2 0.163
Cd4 CD4 antigen 0.161
Cd247 CD247 antigen 0.153
Ctsw cathepsin W 0.147
Cd5 CD5 antigen 0.146
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.146
Cd96 CD96 antigen 0.144
Foxp3 forkhead box P3 0.129
C3ar1 complement component 3a receptor 1 0.123
Sh2d1a SH2 domain protein 1A 0.110
Itgax integrin alpha X 0.106
Klrd1 killer cell lectin-like receptor, subfamily D, member 1 0.101
Il2rg interleukin 2 receptor, gamma chain 0.098
Cd6 CD6 antigen 0.098
Ltb lymphotoxin B 0.093
Cd3d CD3 antigen, delta polypeptide 0.093
Cxcr3 chemokine (C-X-C motif) receptor 3 0.090
Cd8a CD8 antigen, alpha chain 0.088
Gzmb granzyme B 0.087
Folr2 folate receptor 2 (fetal) 0.086
Gzma granzyme A 0.086
Ctla4 cytotoxic T-lymphocyte-associated protein 4 0.085
Ccr6 chemokine (C-C motif) receptor 6 0.084
Xcl1 chemokine (C motif) ligand 1 0.081
Il1b interleukin 1 beta 0.077
Ccr1 chemokine (C-C motif) receptor 1 0.076
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.074
Cd40 CD40 antigen 0.073
Ccr7 chemokine (C-C motif) receptor 7 0.070
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 0.065
Tnfsf8 tumor necrosis factor (ligand) superfamily, member 8 0.065
Fcgr2b Fc receptor, IgG, low affinity IIb 0.064
Lck lymphocyte protein tyrosine kinase 0.062
Ifng interferon gamma 0.060
Lta lymphotoxin A 0.058
Igk immunoglobulin kappa chain complex 0.056
Il27ra interleukin 27 receptor, alpha 0.056
Cxcr2 chemokine (C-X-C motif) receptor 2 0.053
Ccl17 chemokine (C-C motif) ligand 17 0.052
Xcr1 chemokine (C motif) receptor 1 0.052
Cd3g CD3 antigen, gamma polypeptide 0.051
Il18r1 interleukin 18 receptor 1 0.050
Cd22 CD22 antigen 0.050
Tnfsf14 tumor necrosis factor (ligand) superfamily, member 14 0.049
Cd2 CD2 antigen 0.046
Slamf1 signaling lymphocytic activation molecule family member 1 0.046
Mmp12 matrix metallopeptidase 12 0.046
Ptpn22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.046
Pdcd1lg2 programmed cell death 1 ligand 2 0.044
Il6 interleukin 6 0.043
Fasl Fas ligand (TNF superfamily, member 6) 0.042
Ccr5 chemokine (C-C motif) receptor 5 0.042
Casp8 caspase 8 0.041
Il18rap interleukin 18 receptor accessory protein 0.040
Il7r interleukin 7 receptor 0.040
Ccl22 chemokine (C-C motif) ligand 22 0.039
Il2rb interleukin 2 receptor, beta chain 0.039
Cxcl2 chemokine (C-X-C motif) ligand 2 0.038
Rhoh ras homolog gene family, member H 0.037
Prdm1 PR domain containing 1, with ZNF domain 0.036
Gzmk granzyme K 0.036
Fcer2a Fc receptor, IgE, low affinity II, alpha polypeptide 0.035
Il4 interleukin 4 0.034
Gzmc granzyme C 0.034
Klrk1 killer cell lectin-like receptor subfamily K, member 1 0.033
Ccl7 chemokine (C-C motif) ligand 7 0.033
Il12rb2 interleukin 12 receptor, beta 2 0.033
Il10ra interleukin 10 receptor, alpha 0.032
Ubd ubiquitin D 0.031
Stat4 signal transducer and activator of transcription 4 0.031
Ccl12 chemokine (C-C motif) ligand 12 0.030
Ccr8 chemokine (C-C motif) receptor 8 0.030
AF251705 cDNA sequence AF251705 0.030
Ms4a6c membrane-spanning 4-domains, subfamily A, member 6C 0.030
Clec4d C-type lectin domain family 4, member d 0.029
C5ar1 complement component 5a receptor 1 0.028
Cd8b1 CD8 antigen, beta chain 1 0.028
Fcgr1 Fc receptor, IgG, high affinity I 0.028
Gimap7 GTPase, IMAP family member 7 0.028
Cd160 CD160 antigen 0.028
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism