The network for 'regulation of purine nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of purine nucleotide metabolic process

Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.

Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.995
SH3KBP1 SH3-domain kinase binding protein 1 0.995
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.992
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.986
FGFR2 fibroblast growth factor receptor 2 0.978
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.975
PTK2 PTK2 protein tyrosine kinase 2 0.974
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.971
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.965
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.962
RHOA ras homolog gene family, member A 0.958
ARRB1 arrestin, beta 1 0.953
S100A11 S100 calcium binding protein A11 0.928
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.928
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.924
GRB2 growth factor receptor-bound protein 2 0.921
JUN jun proto-oncogene 0.920
EGFR epidermal growth factor receptor 0.911
CCR5 chemokine (C-C motif) receptor 5 0.907
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.904
DNM2 dynamin 2 0.896
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.870
BBS10 Bardet-Biedl syndrome 10 0.866
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.865
RICTOR RPTOR independent companion of MTOR, complex 2 0.862
FLNA filamin A, alpha 0.855
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.845
NCF2 neutrophil cytosolic factor 2 0.835
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.824
TSC2 tuberous sclerosis 2 0.799
CCL5 chemokine (C-C motif) ligand 5 0.796
PLCG1 phospholipase C, gamma 1 0.786
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.784
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.782
TNNC1 troponin C type 1 (slow) 0.772
ERBB2IP erbb2 interacting protein 0.765
S100A6 S100 calcium binding protein A6 0.758
BCR breakpoint cluster region 0.748
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.744
FASLG Fas ligand (TNF superfamily, member 6) 0.738
MARK3 MAP/microtubule affinity-regulating kinase 3 0.737
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.734
TNK2 tyrosine kinase, non-receptor, 2 0.717
CXCL9 chemokine (C-X-C motif) ligand 9 0.712
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.711
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.709
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.708
GRB7 growth factor receptor-bound protein 7 0.704
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.702
DRD2 dopamine receptor D2 0.701
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.699
TLN1 talin 1 0.696
CRHR1 corticotropin releasing hormone receptor 1 0.695
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.694
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.690
KIAA0930 KIAA0930 0.682
CXCL2 chemokine (C-X-C motif) ligand 2 0.673
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.656
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.629
RIN3 Ras and Rab interactor 3 0.625
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.624
ADRBK1 adrenergic, beta, receptor kinase 1 0.618
ZYX zyxin 0.614
S100A8 S100 calcium binding protein A8 0.604
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.600
DOCK1 dedicator of cytokinesis 1 0.599
NCAPD2 non-SMC condensin I complex, subunit D2 0.594
SH3RF1 SH3 domain containing ring finger 1 0.590
BCAR1 breast cancer anti-estrogen resistance 1 0.589
EML3 echinoderm microtubule associated protein like 3 0.573
TPM1 tropomyosin 1 (alpha) 0.571
CCL22 chemokine (C-C motif) ligand 22 0.568
SH3BP2 SH3-domain binding protein 2 0.563
TSC1 tuberous sclerosis 1 0.563
NCKAP1 NCK-associated protein 1 0.560
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.550
GABARAPL1 GABA(A) receptor-associated protein like 1 0.549
SNX9 sorting nexin 9 0.546
LMAN1 lectin, mannose-binding, 1 0.543
ABI1 abl-interactor 1 0.540
NAMPT nicotinamide phosphoribosyltransferase 0.533
SFN stratifin 0.524
CXCL10 chemokine (C-X-C motif) ligand 10 0.520
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.518
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.515
NCK2 NCK adaptor protein 2 0.510
ZMYND11 zinc finger, MYND-type containing 11 0.509
IL8 interleukin 8 0.509
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 0.508
RHOC ras homolog gene family, member C 0.506
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.496
ANKRD28 ankyrin repeat domain 28 0.496
PLEC plectin 0.496
NME2 non-metastatic cells 2, protein (NM23B) expressed in 0.496
BIN1 bridging integrator 1 0.474
CXCL3 chemokine (C-X-C motif) ligand 3 0.474
IFNG interferon, gamma 0.472
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.464
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.462
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
pkg-1 Protein PKG-1 0.289
unc-45 Protein UNC-45 0.214
hif-1 Protein HIF-1 0.208
sem-5 Protein SEM-5 0.187
atg-11 Protein ATG-11 0.175
lin-29 Protein LIN-29 0.148
lag-1 Protein LAG-1 0.121
CELE_F47G4.4 Protein F47G4.4 0.113
unc-79 Protein UNC-79 0.113
zoo-1 Protein ZOO-1 0.111
unc-54 Protein UNC-54 0.111
abts-1 Protein ABTS-1 0.096
snf-1 Protein SNF-1 0.094
goa-1 Protein GOA-1 0.093
sup-17 Protein SUP-17 0.093
lin-45 Protein LIN-45 0.089
unc-26 Protein UNC-26 0.089
mpk-1 Protein MPK-1 0.088
obr-3 Protein OBR-3 0.085
sol-1 Protein SOL-1 0.084
unc-71 Protein UNC-71 0.080
mei-1 Protein MEI-1 0.077
egl-18 Protein EGL-18 0.076
F09A5.4 Protein F09A5.4 0.075
dbl-1 Protein DBL-1 0.074
rgs-7 Protein RGS-7 0.072
F41C3.4 Protein F41C3.4 0.070
fhod-1 Protein FHOD-1 0.069
aha-1 Protein AHA-1 0.069
pqn-39 Protein PQN-39 0.066
gly-7 Protein GLY-7 0.065
CELE_W07A8.2 Protein W07A8.2 0.065
T09B4.9 Protein T09B4.9 0.065
bet-2 Protein BET-2 0.064
sto-4 Protein STO-4 0.063
pat-12 Protein PAT-12 0.063
xpo-1 Protein XPO-1 0.062
elt-6 Protein ELT-6 0.062
etr-1 Protein ETR-1 0.062
apa-2 Protein APA-2 0.061
unc-41 Protein UNC-41 0.058
itr-1 Protein ITR-1 0.057
egl-36 Protein EGL-36 0.056
T04F8.6 Protein T04F8.6 0.056
gpr-1 Protein GPR-1 0.055
ist-1 Protein IST-1 0.054
ZK858.6 Protein ZK858.6 0.053
gpr-2 Protein GPR-2 0.053
gei-4 Protein GEI-4 0.052
rme-4 Protein RME-4 0.051
egl-2 Protein EGL-2 0.051
nuo-3 Protein NUO-3 0.050
crt-1 Protein CRT-1 0.047
lin-7 Protein LIN-7 0.046
ptp-4 Protein PTP-4 0.044
rpm-1 Protein RPM-1 0.043
unc-108 Protein UNC-108 0.042
jnk-1 Protein JNK-1 0.042
madf-5 Protein MADF-5 0.041
myo-3 Protein MYO-3 0.041
ykt-6 Protein YKT-6 0.041
eif-3.F Protein EIF-3.F 0.041
Y55F3BR.8 Protein Y55F3BR.8 0.041
che-13 Protein CHE-13 0.041
R10E12.2 Protein R10E12.2 0.040
egl-27 Protein EGL-27 0.040
unc-103 Protein UNC-103 0.040
sym-4 Protein SYM-4 0.040
sng-1 Protein SNG-1 0.040
C11E4.6 Protein C11E4.6 0.039
unc-15 Protein UNC-15 0.039
CELE_T10D4.6 Protein T10D4.6 0.039
kcc-1 Protein KCC-1 0.039
pqn-55 Protein PQN-55 0.039
unc-104 Protein UNC-104 0.037
abl-1 Protein ABL-1 0.037
lpd-3 Protein LPD-3 0.036
let-70 Protein LET-70 0.036
rsbp-1 Protein RSBP-1 0.036
snf-12 Protein SNF-12 0.036
sek-1 Protein SEK-1 0.036
unc-80 Protein UNC-80 0.036
let-60 Protein LET-60 0.036
mrck-1 Protein MRCK-1 0.035
pdl-1 Protein PDL-1 0.035
unc-94 Protein UNC-94 0.035
sad-1 Protein SAD-1 0.035
zyg-9 Protein ZYG-9 0.034
cri-3 Protein CRI-3 0.034
sma-6 Protein SMA-6 0.034
coh-3 Protein COH-3 0.034
rab-5 Protein RAB-5 0.034
plc-1 Protein PLC-1 0.034
CELE_F52B11.1 Protein F52B11.1 0.034
mab-23 Protein MAB-23 0.034
col-76 Protein COL-76 0.034
cal-4 Protein CAL-4 0.034
rhgf-2 Protein RHGF-2 0.033
cgef-2 Protein CGEF-2 0.033
F35G2.1 Protein F35G2.1 0.033
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
si:dkey-228g21.4 si:dkey-228g21.4 0.636
gnrh2 gonadotropin-releasing hormone 2 0.422
tnni2a.4 troponin I, skeletal, fast 2a.4 0.300
adrb2a adrenergic receptor, beta 2a 0.272
hspa4a heat shock protein 4a 0.266
kal1a Kallmann syndrome 1a sequence 0.265
nf1a neurofibromin 1a 0.247
disc1 disrupted in schizophrenia 1 0.214
th2 tyrosine hydroxylase 2 0.187
bcl2 B-cell leukemia/lymphoma 2 0.182
LOC569642 hypothetical protein LOC569642 0.173
dclk2 doublecortin-like kinase 2 0.169
plxnb2a plexin b2a 0.165
cfl2l cofilin 2, like 0.159
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.155
mchr1b melanin-concentrating hormone receptor 1b 0.145
LOC569128 hypothetical protein LOC569128 0.138
LOC565839 tumor necrosis factor alpha-induced protein 2-like 0.131
drd2l dopamine receptor D2 like 0.129
pvalb2 parvalbumin 2 0.117
mc4r melanocortin 4 receptor 0.114
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.114
ldb1a LIM-domain binding factor 1a 0.111
mcm6 MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae) 0.108
avpl arginine vasopressin-like 0.107
mc2r melanocortin 2 receptor 0.106
jun jun proto-oncogene 0.105
tomm34 translocase of outer mitochondrial membrane 34 0.102
wu:fv91b12 wu:fv91b12 0.102
tpm4 tropomyosin 4 0.098
crhbp corticotropin releasing hormone binding protein 0.093
mc5rb melanocortin 5b receptor 0.090
drd2a dopamine receptor D2a 0.087
adra2c adrenergic, alpha-2C-, receptor 0.082
smyhc2 slow myosin heavy chain 2 0.078
kiss1rb KISS1 receptor b 0.078
spry2 sprouty homolog 2 0.077
dbh dopamine beta hydroxylase 0.077
mc1r melanocortin 1 receptor 0.076
hsp90a.2 heat shock protein 90-alpha 2 0.076
adra2b adrenergic, alpha-2B-, receptor 0.076
bida BH3 interacting domain death agonist 0.072
drd2b dopamine receptor D2b 0.072
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.070
sox4a SRY-box containing gene 4a 0.070
tagln2 transgelin 2 0.064
LOC100535549 cytoplasmic polyadenylation element-binding protein 4-like 0.063
tm9sf2 transmembrane 9 superfamily member 2 0.060
LOC799612 prolactin 2 0.058
pdlim1 PDZ and LIM domain 1 (elfin) 0.054
mecp2 methyl CpG binding protein 2 0.054
rtn1a reticulon 1a 0.053
pdlim3b PDZ and LIM domain 3b 0.052
LOC555482 tachykinin receptor 3-like 0.051
rtcd1 RNA terminal phosphate cyclase domain 1 0.050
cltca clathrin, heavy polypeptide a (Hc) 0.050
tpm3 tropomyosin 3 0.050
gstt1a glutathione S-transferase theta 1a 0.049
zgc:92242 zgc:92242 0.049
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.048
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.048
twist1a twist1a 0.048
crh corticotropin releasing hormone 0.048
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.047
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.047
mchr1a melanin-concentrating hormone receptor 1a 0.046
tnnt3b troponin T3b, skeletal, fast 0.045
hif1ab hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b 0.045
ccna2 cyclin A2 0.045
pparg peroxisome proliferator activated receptor gamma 0.044
tnnc2 troponin C type 2 (fast) 0.044
prickle2 prickle-like 2 (Drosophila) 0.044
sept7b septin 7b 0.044
pvrl1b poliovirus receptor-related 1b 0.044
ncam2 neural cell adhesion molecule 2 0.041
vamp2 vesicle-associated membrane protein 2 0.041
psen1 presenilin 1 0.041
s1pr2 sphingosine-1-phosphate receptor 2 0.041
ucn3l urocortin 3, like 0.040
cpe carboxypeptidase E 0.040
ilk integrin linked kinase 0.040
pitx3 paired-like homeodomain transcription factor 3 0.039
cntfr ciliary neurotrophic factor receptor 0.039
dmbx1a diencephalon/mesencephalon homeobox 1a 0.038
flr fleer 0.038
stau1 staufen, RNA binding protein, homolog 1 (Drosophila) 0.038
inhbaa inhibin, beta Aa 0.037
mc3r melanocortin 3 receptor 0.037
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.037
cldn2 claudin 2 0.037
prdx2 peroxiredoxin 2 0.037
cnn2 calponin 2 0.035
im:7163548 im:7163548 0.035
fkbp5 FK506 binding protein 5 0.035
ppp3cb protein phosphatase 3, catalytic subunit, beta isozyme 0.034
ehd1 EH-domain containing 1 0.034
pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 0.033
clstn1 calsyntenin 1 0.033
si:dkeyp-59a8.4 si:dkeyp-59a8.4 0.033
hcrtr2 hypocretin (orexin) receptor 2 0.033
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.486
Shaw Shaker cognate w 0.411
Rheb CG1081 gene product from transcript CG1081-RA 0.400
dnc dunce 0.360
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.303
Mer Merlin 0.287
eIF-4E Eukaryotic initiation factor 4E 0.241
puc puckered 0.241
Jra Jun-related antigen 0.235
trio CG18214 gene product from transcript CG18214-RA 0.228
Pkn Protein kinase related to protein kinase N 0.224
Khc Kinesin heavy chain 0.221
NaCP60E Na channel protein 60E 0.214
Rya-r44F Ryanodine receptor 44F 0.203
neur neuralized 0.170
Rbsn-5 Rabenosyn-5 0.168
Ank2 Ankyrin 2 0.164
CG6509 CG6509 gene product from transcript CG6509-RB 0.161
Stat92E Signal-transducer and activator of transcription protein at 92E 0.155
stg string 0.134
CG13253 CG13253 gene product from transcript CG13253-RB 0.133
rl rolled 0.129
cno canoe 0.127
rok Rho-kinase 0.124
mbc myoblast city 0.119
N Notch 0.116
Sos Son of sevenless 0.115
Pten CG5671 gene product from transcript CG5671-RB 0.113
G-oalpha47A G protein oalpha 47A 0.110
Nmdar1 NMDA receptor 1 0.105
Apc APC-like 0.099
pod1 CG4532 gene product from transcript CG4532-RF 0.095
Sbf SET domain binding factor 0.092
Galpha49B G protein alpha49B 0.092
Uba1 Ubiquitin activating enzyme 1 0.090
CG11033 CG11033 gene product from transcript CG11033-RB 0.088
insc inscuteable 0.087
Moe Moesin 0.087
stumps CG31317 gene product from transcript CG31317-RC 0.086
Mrtf Myocardin-related transcription factor 0.085
Hr96 Hormone receptor-like in 96 0.084
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.081
plexB plexin B 0.081
Pk92B Protein kinase at 92B 0.080
tai taiman 0.080
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.080
CG9572 CG9572 gene product from transcript CG9572-RA 0.079
Act57B Actin 57B 0.078
CG8334 CG8334 gene product from transcript CG8334-RA 0.078
htl heartless 0.077
DAAM Dishevelled Associated Activator of Morphogenesis 0.075
UBL3 CG9038 gene product from transcript CG9038-RC 0.073
slo slowpoke 0.073
Tre1 trapped in endoderm-1 0.071
didum dilute class unconventional myosin 0.071
cpx complexin 0.070
hig hikaru genki 0.069
synj synaptojanin 0.069
dock dreadlocks 0.069
stv starvin 0.068
Socs36E Suppressor of cytokine signaling at 36E 0.067
Actbeta Activin-beta 0.067
Hph HIF prolyl hydroxylase 0.066
trn tartan 0.065
mbt mushroom bodies tiny 0.065
rols rolling pebbles 0.064
drpr draper 0.064
mGluRA metabotropic glutamate receptor 0.063
CG32772 CG32772 gene product from transcript CG32772-RC 0.063
Wnk CG7177 gene product from transcript CG7177-RA 0.063
Mlp84B Muscle LIM protein at 84B 0.062
bs blistered 0.062
sav salvador 0.062
CycA Cyclin A 0.061
scb scab 0.061
Suv4-20 CG13363 gene product from transcript CG13363-RA 0.060
pkaap CG4132 gene product from transcript CG4132-RA 0.060
Flo-2 flotillin 2 0.060
Plc21C Phospholipase C at 21C 0.060
Caki Calcium/calmodulin-dependent protein kinase 0.060
mib1 mind bomb 1 0.060
sec10 CG6159 gene product from transcript CG6159-RA 0.058
dnr1 defense repressor 1 0.058
ex expanded 0.058
CaMKII Calcium/calmodulin-dependent protein kinase II 0.057
Dap160 Dynamin associated protein 160 0.057
inaD inactivation no afterpotential D 0.057
chic chickadee 0.057
flw flapwing 0.057
neuroligin CG13772 gene product from transcript CG13772-RA 0.056
SNF1A SNF1A/AMP-activated protein kinase 0.056
Atf-2 Activating transcription factor-2 0.056
yata CG1973 gene product from transcript CG1973-RA 0.056
Pde8 Phosphodiesterase 8 0.056
Rala Ras-related protein 0.055
mys myospheroid 0.055
5-HT1B Serotonin receptor 1B 0.055
Cctgamma CG8977 gene product from transcript CG8977-RC 0.053
p120ctn Adherens junction protein p120 0.053
nwk nervous wreck 0.053
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Kl klotho 0.973
Efnb2 ephrin B2 0.971
Ctnnb1 catenin (cadherin associated protein), beta 1 0.955
Bcl2 B-cell leukemia/lymphoma 2 0.941
Epha4 Eph receptor A4 0.931
Pten phosphatase and tensin homolog 0.861
Drd2 dopamine receptor D2 0.858
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.835
Pparg peroxisome proliferator activated receptor gamma 0.834
Arrb2 arrestin, beta 2 0.826
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.800
Hif1a hypoxia inducible factor 1, alpha subunit 0.770
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.764
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.714
Kit kit oncogene 0.710
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.676
Adora2a adenosine A2a receptor 0.675
Ephb2 Eph receptor B2 0.671
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.649
Nos3 nitric oxide synthase 3, endothelial cell 0.644
Vhl von Hippel-Lindau tumor suppressor 0.617
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.602
Rac1 RAS-related C3 botulinum substrate 1 0.592
Cnr1 cannabinoid receptor 1 (brain) 0.584
Lepr leptin receptor 0.568
Wnt2b wingless related MMTV integration site 2b 0.559
Pgr progesterone receptor 0.542
Syn2 synapsin II 0.540
Gdnf glial cell line derived neurotrophic factor 0.539
Nf1 neurofibromatosis 1 0.539
Nos1 nitric oxide synthase 1, neuronal 0.532
Ret ret proto-oncogene 0.532
Braf Braf transforming gene 0.531
Adam17 a disintegrin and metallopeptidase domain 17 0.525
Dlg4 discs, large homolog 4 (Drosophila) 0.518
Plxna1 plexin A1 0.517
Esrrb estrogen related receptor, beta 0.516
Akt1 thymoma viral proto-oncogene 1 0.514
Kitl kit ligand 0.513
Cd44 CD44 antigen 0.512
Prkcc protein kinase C, gamma 0.507
Ednra endothelin receptor type A 0.505
Ilk integrin linked kinase 0.495
Smad3 MAD homolog 3 (Drosophila) 0.494
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.492
Shc3 src homology 2 domain-containing transforming protein C3 0.491
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.490
St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 0.490
Grb2 growth factor receptor bound protein 2 0.485
Arhgap21 Rho GTPase activating protein 21 0.485
Git1 G protein-coupled receptor kinase-interactor 1 0.484
Ednrb endothelin receptor type B 0.479
Prkce protein kinase C, epsilon 0.474
Epas1 endothelial PAS domain protein 1 0.463
Pxn paxillin 0.461
Rictor RPTOR independent companion of MTOR, complex 2 0.447
Trp53 transformation related protein 53 0.444
Cplx1 complexin 1 0.442
Ar androgen receptor 0.431
Fscn1 fascin homolog 1, actin bundling protein (Strongylocentrotus purpuratus) 0.429
Rho rhodopsin 0.429
Crhr1 corticotropin releasing hormone receptor 1 0.428
Hmha1 histocompatibility (minor) HA-1 0.423
Cckbr cholecystokinin B receptor 0.415
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.414
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.412
Tcfcp2l1 transcription factor CP2-like 1 0.407
Fnip1 folliculin interacting protein 1 0.403
Sox10 SRY-box containing gene 10 0.396
Ntf3 neurotrophin 3 0.390
Vdr vitamin D receptor 0.389
Epha1 Eph receptor A1 0.377
Bax BCL2-associated X protein 0.373
Rgnef Rho-guanine nucleotide exchange factor 0.372
Pdgfb platelet derived growth factor, B polypeptide 0.371
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.371
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.367
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.365
Nf2 neurofibromatosis 2 0.365
Anapc2 anaphase promoting complex subunit 2 0.358
Wipf1 WAS/WASL interacting protein family, member 1 0.358
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.356
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.356
Ccr2 chemokine (C-C motif) receptor 2 0.353
Thrb thyroid hormone receptor beta 0.349
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.348
Sh3bp1 SH3-domain binding protein 1 0.344
Capn2 calpain 2 0.343
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.340
Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 0.336
Klf3 Kruppel-like factor 3 (basic) 0.334
Ccl2 chemokine (C-C motif) ligand 2 0.333
Gna13 guanine nucleotide binding protein, alpha 13 0.333
Tsc1 tuberous sclerosis 1 0.332
Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila) 0.331
Amh anti-Mullerian hormone 0.328
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.328
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.328
Mef2a myocyte enhancer factor 2A 0.324
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.321
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Tagln transgelin 0.523
Acta2 smooth muscle alpha-actin 0.466
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.373
Pja2 praja 2, RING-H2 motif containing 0.341
Myl9 myosin, light chain 9, regulatory 0.333
Kcnb2 potassium voltage gated channel, Shab-related subfamily, member 2 0.331
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.307
Gzmk granzyme K 0.303
Hpca hippocalcin 0.283
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.268
Flt1 FMS-related tyrosine kinase 1 0.255
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.253
Adar adenosine deaminase, RNA-specific 0.238
Adora1 adenosine A1 receptor 0.236
Gucy2d guanylate cyclase 2d 0.215
Olr416 olfactory receptor 416 0.209
Fgfr1 Fibroblast growth factor receptor 1 0.203
Klrb1b killer cell lectin-like receptor subfamily B member 1B 0.199
Adora2a adenosine A2a receptor 0.198
Flna filamin A, alpha 0.197
Anxa2 annexin A2 0.192
Akap1 A kinase (PRKA) anchor protein 1 0.186
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.182
Mc5r melanocortin 5 receptor 0.177
Prkch protein kinase C, eta 0.176
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.173
Rgs12 regulator of G-protein signaling 12 0.162
Homer1 homer homolog 1 (Drosophila) 0.159
Cdk5 cyclin-dependent kinase 5 0.156
Actg2 actin, gamma 2, smooth muscle, enteric 0.156
Crhr1 corticotropin releasing hormone receptor 1 0.153
Pld2 phospholipase D2 0.144
Prdm2 PR domain containing 2, with ZNF domain 0.144
Sstr1 somatostatin receptor 1 0.143
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.141
Rorb RAR-related orphan receptor B 0.138
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.135
Utrn utrophin 0.134
Figf c-fos induced growth factor 0.134
Notch3 Notch homolog 3 (Drosophila) 0.134
Arpc2 actin related protein 2/3 complex, subunit 2 0.132
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.131
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.131
Opn1mw opsin 1 (cone pigments), medium-wave-sensitive 0.127
Ece1 endothelin converting enzyme 1 0.126
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.126
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.124
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.124
Gad2 glutamate decarboxylase 2 0.124
Myo1b myosin Ib 0.124
Sidt1 SID1 transmembrane family, member 1 0.119
Crip cysteine-rich intestinal protein 0.119
Rgs4 regulator of G-protein signaling 4 0.118
Smr3a submaxillary gland androgen regulated protein 3A 0.117
Ryr2 ryanodine receptor 2, cardiac 0.117
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.117
Cfp complement factor properdin 0.116
Trhr2 thyrotropin releasing hormone receptor 2 0.114
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.114
Freq frequenin homolog (Drosophila) 0.114
Cd86 CD86 molecule 0.113
Snap25 synaptosomal-associated protein 25 0.112
Arl1 ADP-ribosylation factor-like 1 0.111
Copb1 coatomer protein complex, subunit beta 1 0.110
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.110
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.109
Rgs9 regulator of G-protein signaling 9 0.109
Nfasc neurofascin 0.108
Myo16 myosin XVI 0.107
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.107
S100a4 S100 calcium-binding protein A4 0.107
Gria1 glutamate receptor, ionotropic, AMPA 1 0.105
Plcg1 phospholipase C, gamma 1 0.104
Map6 microtubule-associated protein 6 0.103
Map4k3 mitogen-activated protein kinase kinase kinase kinase 3 0.102
Aqp2 aquaporin 2 (collecting duct) 0.102
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.100
Atp12a ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.100
Bok BCL2-related ovarian killer 0.100
Cela2a chymotrypsin-like elastase family, member 2A 0.100
Syt7 synaptotagmin VII 0.100
Esam endothelial cell adhesion molecule 0.099
Slc9a4 solute carrier family 9 (sodium/hydrogen exchanger), member 4 0.098
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.098
Ncan neurocan 0.098
Hcrt hypocretin 0.095
Dad1 defender against cell death 1 0.094
Nrp2 neuropilin 2 0.093
Tek TEK tyrosine kinase, endothelial 0.093
Ctrc chymotrypsin C (caldecrin) 0.093
Ptprq protein tyrosine phosphatase, receptor type, Q 0.092
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.090
Rap1b RAP1B, member of RAS oncogene family 0.090
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.090
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.088
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.088
Chrna3 cholinergic receptor, nicotinic, alpha 3 0.088
Neurod2 neurogenic differentiation 2 0.087
Vcsa1 variable coding sequence A1 0.086
Scn3b sodium channel, voltage-gated, type III, beta 0.086
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STE5 Ste5p 0.265
RHO1 Rho1p 0.217
GYL1 Gyl1p 0.167
SPA2 Spa2p 0.150
STE11 Ste11p 0.119
MKK1 Mkk1p 0.117
ROM2 Rom2p 0.116
GCD6 Gcd6p 0.112
SUI3 Sui3p 0.100
GDI1 Gdi1p 0.099
CDC24 Cdc24p 0.099
YPT53 Ypt53p 0.093
BEM3 Bem3p 0.079
GCD7 Gcd7p 0.079
STE4 Ste4p 0.078
VPS4 Vps4p 0.066
STI1 Sti1p 0.066
VTA1 Vta1p 0.065
MNN9 Mnn9p 0.063
STT4 Stt4p 0.063
GPB2 Gpb2p 0.061
KOG1 Kog1p 0.059
CDC12 Cdc12p 0.055
SEC16 Sec16p 0.054
AVO1 Avo1p 0.051
TRS65 Trs65p 0.050
EXO84 Exo84p 0.049
GDS1 Gds1p 0.049
VPS60 Vps60p 0.047
FYV8 Fyv8p 0.047
CHS1 Chs1p 0.044
GPR1 Gpr1p 0.044
COX9 Cox9p 0.043
NUP85 Nup85p 0.043
INP52 Inp52p 0.043
FMS1 Fms1p 0.042
SSK2 Ssk2p 0.041
ATP1 Atp1p 0.041
SLM1 Slm1p 0.041
NDE1 Nde1p 0.040
HUA2 Hua2p 0.040
YME1 Yme1p 0.039
CCT8 Cct8p 0.037
FKH1 Fkh1p 0.037
PEP5 Pep5p 0.037
BEM2 Bem2p 0.037
VPS15 Vps15p 0.037
YJL144W hypothetical protein 0.037
CRM1 Crm1p 0.036
MYO2 Myo2p 0.036
MID1 Mid1p 0.036
MCM4 Mcm4p 0.035
RGA2 Rga2p 0.035
MCM3 Mcm3p 0.035
SOG2 Sog2p 0.035
NAT1 Nat1p 0.035
ITR2 Itr2p 0.035
PMI40 Pmi40p 0.035
YJR085C hypothetical protein 0.035
YHR033W hypothetical protein 0.035
SLT2 Slt2p 0.034
GIC2 Gic2p 0.034
INP53 Inp53p 0.034
ORC2 Orc2p 0.034
HOR2 Hor2p 0.033
BST1 Bst1p 0.033
MBF1 Mbf1p 0.033
BFR1 Bfr1p 0.033
SUB2 Sub2p 0.032
NUP2 Nup2p 0.032
SEC53 Sec53p 0.032
SEC13 Sec13p 0.032
FUM1 Fum1p 0.031
PPH21 Pph21p 0.031
RKI1 Rki1p 0.031
YHR127W hypothetical protein 0.031
TRS85 Trs85p 0.031
LHS1 Lhs1p 0.031
SLH1 Slh1p 0.031
KEL1 Kel1p 0.031
PRD1 Prd1p 0.031
MSP1 Msp1p 0.031
HYP2 Hyp2p 0.031
CLN3 Cln3p 0.030
RFC1 Rfc1p 0.030
VPS9 Vps9p 0.030
YIR035C hypothetical protein 0.030
TCA17 Tca17p 0.030
IST1 Ist1p 0.030
FES1 Fes1p 0.030
INH1 Inh1p 0.030
MDS3 Mds3p 0.029
PMR1 Pmr1p 0.029
YPT52 Ypt52p 0.029
BRN1 Brn1p 0.029
MSA1 Msa1p 0.029
BIT61 Bit61p 0.029
ARP10 Arp10p 0.029
RGD2 Rgd2p 0.028
BET3 Bet3p 0.028