The network for 'nervous system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nervous system development

The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.

Name Description Probability Func Analog Organism
TP53 tumor protein p53 1.000
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
EGFR epidermal growth factor receptor 1.000
CREBBP CREB binding protein 1.000
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 1.000
ESR1 estrogen receptor 1 1.000
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.999
UBC ubiquitin C 0.999
NCOR1 nuclear receptor corepressor 1 0.998
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.998
FYN FYN oncogene related to SRC, FGR, YES 0.997
NCOA1 nuclear receptor coactivator 1 0.996
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.993
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.993
EP300 E1A binding protein p300 0.992
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.992
RB1 retinoblastoma 1 0.991
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.989
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.987
SMAD4 SMAD family member 4 0.987
ATXN1 ataxin 1 0.985
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.985
FN1 fibronectin 1 0.984
NCOR2 nuclear receptor corepressor 2 0.981
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.981
GRB2 growth factor receptor-bound protein 2 0.981
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.980
FLNA filamin A, alpha 0.980
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.978
JUN jun proto-oncogene 0.975
SFN stratifin 0.973
ACTB actin, beta 0.972
SMAD2 SMAD family member 2 0.962
SP1 Sp1 transcription factor 0.952
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.948
RARA retinoic acid receptor, alpha 0.947
CSNK2A1 casein kinase 2, alpha 1 polypeptide 0.938
AR androgen receptor 0.938
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.932
MAPK8 mitogen-activated protein kinase 8 0.931
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.929
ATF2 activating transcription factor 2 0.929
CDK2 cyclin-dependent kinase 2 0.929
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.928
NCOA3 nuclear receptor coactivator 3 0.927
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.921
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.919
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.913
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.905
DDX5 DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 0.904
RAD21 RAD21 homolog (S. pombe) 0.901
SOCS3 suppressor of cytokine signaling 3 0.886
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.883
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.883
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.875
MAPK14 mitogen-activated protein kinase 14 0.875
NCOA2 nuclear receptor coactivator 2 0.874
RUNX1 runt-related transcription factor 1 0.871
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.869
MYH9 myosin, heavy chain 9, non-muscle 0.850
CSNK2B casein kinase 2, beta polypeptide 0.848
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.847
DLG4 discs, large homolog 4 (Drosophila) 0.845
GSK3B glycogen synthase kinase 3 beta 0.844
TRIM33 tripartite motif containing 33 0.825
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.821
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.820
SMAD3 SMAD family member 3 0.813
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.806
IQGAP1 IQ motif containing GTPase activating protein 1 0.803
HDAC2 histone deacetylase 2 0.793
SOX2 SRY (sex determining region Y)-box 2 0.789
CSNK1E casein kinase 1, epsilon 0.788
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.781
BCL3 B-cell CLL/lymphoma 3 0.780
CFL1 cofilin 1 (non-muscle) 0.776
HDAC4 histone deacetylase 4 0.775
FGFR2 fibroblast growth factor receptor 2 0.774
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.770
YAP1 Yes-associated protein 1 0.769
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.764
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.761
PKM2 pyruvate kinase, muscle 0.759
MAPT microtubule-associated protein tau 0.756
TCF12 transcription factor 12 0.751
MYOD1 myogenic differentiation 1 0.751
MAPK1 mitogen-activated protein kinase 1 0.749
JAG1 jagged 1 0.747
APC adenomatous polyposis coli 0.744
FOXD3 forkhead box D3 0.728
CAV1 caveolin 1, caveolae protein, 22kDa 0.727
CUL1 cullin 1 0.722
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.717
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.715
CDC27 cell division cycle 27 homolog (S. cerevisiae) 0.715
HDAC1 histone deacetylase 1 0.715
FGF1 fibroblast growth factor 1 (acidic) 0.714
TAL1 T-cell acute lymphocytic leukemia 1 0.714
MED1 mediator complex subunit 1 0.708
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.706
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
egl-18 Protein EGL-18 0.995
vab-3 Protein VAB-3 0.971
unc-9 Protein UNC-9 0.953
unc-73 Protein UNC-73 0.887
goa-1 Protein GOA-1 0.865
ida-1 Protein IDA-1 0.818
unc-42 Protein UNC-42 0.781
hcp-3 Protein HCP-3 0.771
ect-2 Protein ECT-2 0.750
zyg-9 Protein ZYG-9 0.739
ceh-20 Protein CEH-20 0.734
egl-46 Protein EGL-46 0.722
pry-1 Protein PRY-1 0.692
clh-5 Protein CLH-5 0.691
glp-1 Protein GLP-1 0.688
T27A3.1 Protein T27A3.1 0.686
unc-53 Protein UNC-53 0.673
rig-6 Protein RIG-6 0.664
epi-1 Protein EPI-1 0.656
pdfr-1 Protein PDFR-1 0.638
sdz-28 Protein SDZ-28 0.623
mec-2 Protein MEC-2 0.621
pha-4 Protein PHA-4 0.620
eor-1 Protein EOR-1 0.572
daf-11 Protein DAF-11 0.557
egl-13 Protein EGL-13 0.542
bar-1 Protein BAR-1 0.527
R90.1 Protein R90.1 0.522
sma-6 Protein SMA-6 0.518
C11E4.6 Protein C11E4.6 0.492
wrm-1 Protein WRM-1 0.492
elt-6 Protein ELT-6 0.482
scc-3 Protein SCC-3 0.477
let-502 Protein LET-502 0.475
pkg-1 Protein PKG-1 0.474
hsr-9 Protein HSR-9 0.468
dnc-2 Protein DNC-2 0.466
zag-1 Protein ZAG-1 0.462
unc-6 Protein UNC-6 0.458
scc-1 Protein SCC-1 0.458
F33H2.3 Protein F33H2.3 0.456
hbl-1 Protein HBL-1 0.450
sng-1 Protein SNG-1 0.449
nhr-67 Protein NHR-67 0.449
F33D11.10 Protein F33D11.10 0.442
fln-2 Protein FLN-2 0.439
unc-62 Protein UNC-62 0.439
sli-1 Protein SLI-1 0.429
npp-5 Protein NPP-5 0.425
mep-1 Protein MEP-1 0.419
pxf-1 Protein PXF-1 0.411
inx-13 Protein INX-13 0.406
plc-1 Protein PLC-1 0.401
let-60 Protein LET-60 0.394
ain-1 Protein AIN-1 0.386
nhr-2 Protein NHR-2 0.384
che-3 Protein CHE-3 0.384
F53F10.2 Protein F53F10.2 0.381
daf-19 Protein DAF-19 0.381
egl-36 Protein EGL-36 0.379
zip-7 Protein ZIP-7 0.372
lst-3 Protein LST-3 0.368
unc-40 Protein UNC-40 0.366
gon-4 Protein GON-4 0.359
par-5 Protein PAR-5 0.358
F56D12.6 Protein F56D12.6 0.358
egl-44 Protein EGL-44 0.349
apr-1 Protein APR-1 0.348
apl-1 Protein APL-1 0.348
T07A9.10 Protein T07A9.10 0.346
rig-5 Protein RIG-5 0.344
sax-3 Protein SAX-3 0.344
hda-1 Protein HDA-1 0.340
unc-52 Protein UNC-52 0.338
egl-27 Protein EGL-27 0.331
C54E4.2 Protein C54E4.2 0.330
spc-1 Protein SPC-1 0.330
ubxn-2 Protein UBXN-2 0.330
unc-104 Protein UNC-104 0.330
age-1 Protein AGE-1 0.329
fkh-2 Protein FKH-2 0.328
dep-1 Protein DEP-1 0.326
daf-12 Protein DAF-12 0.325
lin-12 Protein LIN-12 0.321
CELE_F53F4.11 Protein F53F4.11 0.316
osm-5 Protein OSM-5 0.316
osm-3 Protein OSM-3 0.312
R10E12.2 Protein R10E12.2 0.309
gsp-1 Protein GSP-1 0.309
gck-2 Protein GCK-2 0.308
myo-3 Protein MYO-3 0.306
rpn-8 Protein RPN-8 0.303
xpo-1 Protein XPO-1 0.302
R03H10.2 Protein R03H10.2 0.301
prp-21 Protein PRP-21 0.301
rpt-3 Protein RPT-3 0.300
lam-2 Protein LAM-2 0.300
lrp-2 Protein LRP-2 0.299
gld-1 Protein GLD-1 0.299
magi-1 Protein MAGI-1 0.296
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism