IMP
Process View
The network for 'establishment of lymphocyte polarity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
establishment of lymphocyte polarity
The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCL4 | chemokine (C-C motif) ligand 4 | 0.995 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.984 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.981 | |
| IL8 | interleukin 8 | 0.961 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.958 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.935 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.909 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.899 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.882 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.854 | |
| IDE | insulin-degrading enzyme | 0.754 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.685 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.651 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.609 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.539 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.520 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.464 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.406 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.392 | |
| TNF | tumor necrosis factor | 0.352 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.321 | |
| IL1B | interleukin 1, beta | 0.281 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.272 | |
| DARC | Duffy blood group, chemokine receptor | 0.271 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.249 | |
| MYL9 | myosin, light chain 9, regulatory | 0.205 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.195 | |
| SELE | selectin E | 0.180 | |
| CD83 | CD83 molecule | 0.176 | |
| TPM4 | tropomyosin 4 | 0.168 | |
| ZYX | zyxin | 0.164 | |
| UBD | ubiquitin D | 0.154 | |
| IFNG | interferon, gamma | 0.152 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.130 | |
| FPR3 | formyl peptide receptor 3 | 0.121 | |
| IL7R | interleukin 7 receptor | 0.119 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.110 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.108 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.108 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.106 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.105 | |
| RGS1 | regulator of G-protein signaling 1 | 0.100 | |
| FLNA | filamin A, alpha | 0.084 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.081 | |
| IL2RG | interleukin 2 receptor, gamma | 0.078 | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.078 | |
| SLAMF8 | SLAM family member 8 | 0.077 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.073 | |
| ARRB1 | arrestin, beta 1 | 0.071 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.067 | |
| CH25H | cholesterol 25-hydroxylase | 0.062 | |
| IL1RN | interleukin 1 receptor antagonist | 0.062 | |
| CLEC10A | C-type lectin domain family 10, member A | 0.060 | |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.059 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.054 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.053 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.052 | |
| EBI3 | Epstein-Barr virus induced 3 | 0.051 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.046 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.043 | |
| APOC1 | apolipoprotein C-I | 0.043 | |
| XCL2 | chemokine (C motif) ligand 2 | 0.042 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.040 | |
| IL32 | interleukin 32 | 0.039 | |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.037 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.037 | |
| MSC | musculin | 0.037 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.036 | |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.035 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.035 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.032 | |
| CD80 | CD80 molecule | 0.031 | |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.031 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.030 | |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.029 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.029 | |
| SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.029 | |
| XCL1 | chemokine (C motif) ligand 1 | 0.029 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.028 | |
| GNLY | granulysin | 0.028 | |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.027 | |
| CCL23 | chemokine (C-C motif) ligand 23 | 0.026 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.026 | |
| IL21R | interleukin 21 receptor | 0.025 | |
| LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.024 | |
| SLAMF7 | SLAM family member 7 | 0.024 | |
| CD69 | CD69 molecule | 0.024 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.024 | |
| IL2RB | interleukin 2 receptor, beta | 0.023 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.023 | |
| INHBA | inhibin, beta A | 0.023 | |
| STAT4 | signal transducer and activator of transcription 4 | 0.022 | |
| NKG7 | natural killer cell group 7 sequence | 0.022 | |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.022 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.021 | |
| RGS16 | regulator of G-protein signaling 16 | 0.021 | |
| IL10 | interleukin 10 | 0.020 | |
| C2 | complement component 2 | 0.020 | |
| DPT | dermatopontin | 0.020 | |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.020 |
Loading network...
Mus musculus
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Chrm2 | cholinergic receptor, muscarinic 2, cardiac | 0.305 | |
| Ywhaz | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.203 | |
| Efna1 | ephrin A1 | 0.196 | |
| Efnb2 | ephrin B2 | 0.146 | |
| Iqcb1 | IQ calmodulin-binding motif containing 1 | 0.104 | |
| Nsf | N-ethylmaleimide sensitive fusion protein | 0.073 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.059 | |
| Ntf3 | neurotrophin 3 | 0.055 | |
| Cxcr4 | chemokine (C-X-C motif) receptor 4 | 0.050 | |
| Actn1 | actinin, alpha 1 | 0.048 | |
| Rpgrip1l | Rpgrip1-like | 0.047 | |
| Ywhab | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.032 | |
| Iqgap1 | IQ motif containing GTPase activating protein 1 | 0.029 | |
| Msn | moesin | 0.028 | |
| Invs | inversin | 0.022 | |
| Eno1 | enolase 1, alpha non-neuron | 0.020 | |
| Dlgap1 | discs, large (Drosophila) homolog-associated protein 1 | 0.019 | |
| Tuba1a | tubulin, alpha 1A | 0.017 | |
| Adm | adrenomedullin | 0.015 | |
| Cnn1 | calponin 1 | 0.013 | |
| Ptk2b | PTK2 protein tyrosine kinase 2 beta | 0.012 | |
| Elmo1 | engulfment and cell motility 1, ced-12 homolog (C. elegans) | 0.011 | |
| Chd5 | chromodomain helicase DNA binding protein 5 | 0.010 | |
| Acta2 | actin, alpha 2, smooth muscle, aorta | 0.010 |