IMP
Process View
The network for 'negative regulation of t helper 1 cell activation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of t helper 1 cell activation
Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CCR5 | chemokine (C-C motif) receptor 5 | 1.000 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.999 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.998 | |
| CCL13 | chemokine (C-C motif) ligand 13 | 0.968 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.964 | |
| IL8 | interleukin 8 | 0.924 | |
| CCL22 | chemokine (C-C motif) ligand 22 | 0.920 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.915 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.871 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.865 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.843 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.806 | |
| IDE | insulin-degrading enzyme | 0.760 | |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.716 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.695 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.677 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.661 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.580 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.569 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.546 | |
| IL1B | interleukin 1, beta | 0.439 | |
| CCL7 | chemokine (C-C motif) ligand 7 | 0.418 | |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.408 | |
| CCL3 | chemokine (C-C motif) ligand 3 | 0.371 | |
| IL7R | interleukin 7 receptor | 0.360 | |
| IFNG | interferon, gamma | 0.359 | |
| IL2RB | interleukin 2 receptor, beta | 0.336 | |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.331 | |
| CD83 | CD83 molecule | 0.304 | |
| TNF | tumor necrosis factor | 0.302 | |
| CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.292 | |
| RGS1 | regulator of G-protein signaling 1 | 0.281 | |
| UBD | ubiquitin D | 0.272 | |
| CCR4 | chemokine (C-C motif) receptor 4 | 0.263 | |
| PRF1 | perforin 1 (pore forming protein) | 0.223 | |
| IL10 | interleukin 10 | 0.205 | |
| ICAM1 | intercellular adhesion molecule 1 | 0.193 | |
| SELE | selectin E | 0.181 | |
| VCAM1 | vascular cell adhesion molecule 1 | 0.168 | |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.156 | |
| MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.150 | |
| GNLY | granulysin | 0.126 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.124 | |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.116 | |
| IDO1 | indoleamine 2,3-dioxygenase 1 | 0.115 | |
| CCR3 | chemokine (C-C motif) receptor 3 | 0.111 | |
| CCL19 | chemokine (C-C motif) ligand 19 | 0.107 | |
| ARRB1 | arrestin, beta 1 | 0.094 | |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.093 | |
| FPR3 | formyl peptide receptor 3 | 0.082 | |
| TRAF1 | TNF receptor-associated factor 1 | 0.081 | |
| CCR1 | chemokine (C-C motif) receptor 1 | 0.079 | |
| KLRD1 | killer cell lectin-like receptor subfamily D, member 1 | 0.070 | |
| CH25H | cholesterol 25-hydroxylase | 0.070 | |
| CD69 | CD69 molecule | 0.068 | |
| LAMP3 | lysosomal-associated membrane protein 3 | 0.067 | |
| DARC | Duffy blood group, chemokine receptor | 0.058 | |
| CCL3L3 | chemokine (C-C motif) ligand 3-like 3 | 0.057 | |
| LAG3 | lymphocyte-activation gene 3 | 0.057 | |
| IL2RA | interleukin 2 receptor, alpha | 0.057 | |
| IL21R | interleukin 21 receptor | 0.056 | |
| ADAMDEC1 | ADAM-like, decysin 1 | 0.053 | |
| IL18RAP | interleukin 18 receptor accessory protein | 0.052 | |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.050 | |
| CCL17 | chemokine (C-C motif) ligand 17 | 0.049 | |
| SLAMF7 | SLAM family member 7 | 0.047 | |
| KLRB1 | killer cell lectin-like receptor subfamily B, member 1 | 0.045 | |
| EBI3 | Epstein-Barr virus induced 3 | 0.045 | |
| IL1A | interleukin 1, alpha | 0.045 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.044 | |
| MSC | musculin | 0.044 | |
| XCL1 | chemokine (C motif) ligand 1 | 0.043 | |
| IL32 | interleukin 32 | 0.042 | |
| CCL21 | chemokine (C-C motif) ligand 21 | 0.042 | |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.039 | |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.038 | |
| BCL2A1 | BCL2-related protein A1 | 0.033 | |
| IL1RN | interleukin 1 receptor antagonist | 0.032 | |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.032 | |
| CCL11 | chemokine (C-C motif) ligand 11 | 0.032 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.031 | |
| NKG7 | natural killer cell group 7 sequence | 0.031 | |
| TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 0.029 | |
| CD40LG | CD40 ligand | 0.027 | |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.027 | |
| RGS16 | regulator of G-protein signaling 16 | 0.027 | |
| CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.026 | |
| SLAMF8 | SLAM family member 8 | 0.026 | |
| IL2RG | interleukin 2 receptor, gamma | 0.025 | |
| CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.025 | |
| CD2 | CD2 molecule | 0.024 | |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.023 | |
| RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.023 | |
| CD160 | CD160 molecule | 0.023 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.022 | |
| IL10RA | interleukin 10 receptor, alpha | 0.022 | |
| MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.022 | |
| INHBA | inhibin, beta A | 0.022 | |
| CCL23 | chemokine (C-C motif) ligand 23 | 0.021 | |
| HLA-DRB4 | major histocompatibility complex, class II, DR beta 4 | 0.021 |
