Process View
The network for 'forebrain radial glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Shh | sonic hedgehog | 1.000 | |
Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 1.000 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.999 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.999 | |
Lef1 | lymphoid enhancer binding factor 1 | 0.996 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.993 | |
Sox2 | SRY-box containing gene 2 | 0.989 | |
Foxc1 | forkhead box C1 | 0.980 | |
Bmp4 | bone morphogenetic protein 4 | 0.977 | |
Msx1 | homeobox, msh-like 1 | 0.969 | |
Sox9 | SRY-box containing gene 9 | 0.957 | |
Smo | smoothened homolog (Drosophila) | 0.952 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.949 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.943 | |
Pax3 | paired box gene 3 | 0.932 | |
Bmp7 | bone morphogenetic protein 7 | 0.932 | |
Foxg1 | forkhead box G1 | 0.928 | |
Msx2 | homeobox, msh-like 2 | 0.922 | |
Chd7 | chromodomain helicase DNA binding protein 7 | 0.917 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.909 | |
Ptch1 | patched homolog 1 | 0.900 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.896 | |
Pax6 | paired box gene 6 | 0.865 | |
Meox2 | mesenchyme homeobox 2 | 0.862 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.854 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.842 | |
Foxc2 | forkhead box C2 | 0.806 | |
Pax2 | paired box gene 2 | 0.802 | |
Prrx1 | paired related homeobox 1 | 0.782 | |
Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.771 | |
Fgf8 | fibroblast growth factor 8 | 0.767 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.767 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.751 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.729 | |
Dlx5 | distal-less homeobox 5 | 0.681 | |
Tcfap2a | transcription factor AP-2, alpha | 0.680 | |
Ptk7 | PTK7 protein tyrosine kinase 7 | 0.677 | |
Prrx2 | paired related homeobox 2 | 0.658 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.644 | |
Tbx3 | T-box 3 | 0.639 | |
Nog | noggin | 0.607 | |
En1 | engrailed 1 | 0.593 | |
Tgfb2 | transforming growth factor, beta 2 | 0.557 | |
Sox11 | SRY-box containing gene 11 | 0.520 | |
Rarg | retinoic acid receptor, gamma | 0.517 | |
Psen1 | presenilin 1 | 0.507 | |
Fgf10 | fibroblast growth factor 10 | 0.498 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.480 | |
Gbx2 | gastrulation brain homeobox 2 | 0.472 | |
Rac1 | RAS-related C3 botulinum substrate 1 | 0.431 | |
Tcf7 | transcription factor 7, T-cell specific | 0.373 | |
Trp63 | transformation related protein 63 | 0.368 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.348 | |
Bmper | BMP-binding endothelial regulator | 0.338 | |
Rarb | retinoic acid receptor, beta | 0.334 | |
Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.310 | |
Rb1 | retinoblastoma 1 | 0.309 | |
Runx2 | runt related transcription factor 2 | 0.308 | |
Efnb2 | ephrin B2 | 0.299 | |
Apaf1 | apoptotic peptidase activating factor 1 | 0.281 | |
Hoxa1 | homeobox A1 | 0.280 | |
Tbx1 | T-box 1 | 0.261 | |
Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.258 | |
Pten | phosphatase and tensin homolog | 0.256 | |
Gsk3b | glycogen synthase kinase 3 beta | 0.254 | |
Jag1 | jagged 1 | 0.238 | |
Pbx1 | pre B-cell leukemia transcription factor 1 | 0.225 | |
Lrp6 | low density lipoprotein receptor-related protein 6 | 0.216 | |
Rara | retinoic acid receptor, alpha | 0.216 | |
Twist2 | twist homolog 2 (Drosophila) | 0.210 | |
Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.207 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.193 | |
Apoe | apolipoprotein E | 0.188 | |
Hoxa2 | homeobox A2 | 0.181 | |
Bmp2 | bone morphogenetic protein 2 | 0.167 | |
Alx1 | ALX homeobox 1 | 0.166 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.161 | |
Col2a1 | collagen, type II, alpha 1 | 0.161 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.158 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.142 | |
Efnb1 | ephrin B1 | 0.140 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.135 | |
Lhx1 | LIM homeobox protein 1 | 0.129 | |
Dll1 | delta-like 1 (Drosophila) | 0.129 | |
Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.124 | |
Cdon | cell adhesion molecule-related/down-regulated by oncogenes | 0.119 | |
Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.116 | |
Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.116 | |
Sox3 | SRY-box containing gene 3 | 0.115 | |
Insm1 | insulinoma-associated 1 | 0.112 | |
Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.107 | |
T | brachyury | 0.100 | |
Tcfap2c | transcription factor AP-2, gamma | 0.099 | |
Chrd | chordin | 0.098 | |
Rdh10 | retinol dehydrogenase 10 (all-trans) | 0.097 | |
Tax1bp3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.094 | |
Hesx1 | homeobox gene expressed in ES cells | 0.093 | |
Apc | adenomatosis polyposis coli | 0.092 |