The network for 'forebrain radial glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

forebrain radial glial cell differentiation

The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.

Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Gli2 GLI-Kruppel family member GLI2 0.999
Fgfr1 fibroblast growth factor receptor 1 0.999
Lef1 lymphoid enhancer binding factor 1 0.996
Otx2 orthodenticle homolog 2 (Drosophila) 0.993
Sox2 SRY-box containing gene 2 0.989
Foxc1 forkhead box C1 0.980
Bmp4 bone morphogenetic protein 4 0.977
Msx1 homeobox, msh-like 1 0.969
Sox9 SRY-box containing gene 9 0.957
Smo smoothened homolog (Drosophila) 0.952
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.949
Fgfr3 fibroblast growth factor receptor 3 0.943
Pax3 paired box gene 3 0.932
Bmp7 bone morphogenetic protein 7 0.932
Foxg1 forkhead box G1 0.928
Msx2 homeobox, msh-like 2 0.922
Chd7 chromodomain helicase DNA binding protein 7 0.917
Emx1 empty spiracles homolog 1 (Drosophila) 0.909
Ptch1 patched homolog 1 0.900
Emx2 empty spiracles homolog 2 (Drosophila) 0.896
Pax6 paired box gene 6 0.865
Meox2 mesenchyme homeobox 2 0.862
Zeb1 zinc finger E-box binding homeobox 1 0.854
Eya1 eyes absent 1 homolog (Drosophila) 0.842
Foxc2 forkhead box C2 0.806
Pax2 paired box gene 2 0.802
Prrx1 paired related homeobox 1 0.782
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.771
Fgf8 fibroblast growth factor 8 0.767
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.767
Pitx2 paired-like homeodomain transcription factor 2 0.751
Vangl2 vang-like 2 (van gogh, Drosophila) 0.729
Dlx5 distal-less homeobox 5 0.681
Tcfap2a transcription factor AP-2, alpha 0.680
Ptk7 PTK7 protein tyrosine kinase 7 0.677
Prrx2 paired related homeobox 2 0.658
Hes1 hairy and enhancer of split 1 (Drosophila) 0.644
Tbx3 T-box 3 0.639
Nog noggin 0.607
En1 engrailed 1 0.593
Tgfb2 transforming growth factor, beta 2 0.557
Sox11 SRY-box containing gene 11 0.520
Rarg retinoic acid receptor, gamma 0.517
Psen1 presenilin 1 0.507
Fgf10 fibroblast growth factor 10 0.498
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.480
Gbx2 gastrulation brain homeobox 2 0.472
Rac1 RAS-related C3 botulinum substrate 1 0.431
Tcf7 transcription factor 7, T-cell specific 0.373
Trp63 transformation related protein 63 0.368
Otx1 orthodenticle homolog 1 (Drosophila) 0.348
Bmper BMP-binding endothelial regulator 0.338
Rarb retinoic acid receptor, beta 0.334
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.310
Rb1 retinoblastoma 1 0.309
Runx2 runt related transcription factor 2 0.308
Efnb2 ephrin B2 0.299
Apaf1 apoptotic peptidase activating factor 1 0.281
Hoxa1 homeobox A1 0.280
Tbx1 T-box 1 0.261
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.258
Pten phosphatase and tensin homolog 0.256
Gsk3b glycogen synthase kinase 3 beta 0.254
Jag1 jagged 1 0.238
Pbx1 pre B-cell leukemia transcription factor 1 0.225
Lrp6 low density lipoprotein receptor-related protein 6 0.216
Rara retinoic acid receptor, alpha 0.216
Twist2 twist homolog 2 (Drosophila) 0.210
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.207
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.193
Apoe apolipoprotein E 0.188
Hoxa2 homeobox A2 0.181
Bmp2 bone morphogenetic protein 2 0.167
Alx1 ALX homeobox 1 0.166
Notch1 Notch gene homolog 1 (Drosophila) 0.161
Col2a1 collagen, type II, alpha 1 0.161
Wnt3a wingless-related MMTV integration site 3A 0.158
Smad6 MAD homolog 6 (Drosophila) 0.142
Efnb1 ephrin B1 0.140
Hand1 heart and neural crest derivatives expressed transcript 1 0.135
Lhx1 LIM homeobox protein 1 0.129
Dll1 delta-like 1 (Drosophila) 0.129
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.124
Cdon cell adhesion molecule-related/down-regulated by oncogenes 0.119
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.116
Bmpr1a bone morphogenetic protein receptor, type 1A 0.116
Sox3 SRY-box containing gene 3 0.115
Insm1 insulinoma-associated 1 0.112
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.107
T brachyury 0.100
Tcfap2c transcription factor AP-2, gamma 0.099
Chrd chordin 0.098
Rdh10 retinol dehydrogenase 10 (all-trans) 0.097
Tax1bp3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.094
Hesx1 homeobox gene expressed in ES cells 0.093
Apc adenomatosis polyposis coli 0.092
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism