The network for 'intracellular receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

intracellular receptor signaling pathway

Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.

Mus musculus
Name Description Probability Func Analog Organism
Rxra retinoid X receptor alpha 0.991
Pitx2 paired-like homeodomain transcription factor 2 0.985
Ghr growth hormone receptor 0.971
Clock circadian locomotor output cycles kaput 0.956
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.951
Lepr leptin receptor 0.950
Lyz2 lysozyme 2 0.950
Esr1 estrogen receptor 1 (alpha) 0.940
Thrb thyroid hormone receptor beta 0.934
Per2 period homolog 2 (Drosophila) 0.928
Kiss1 KiSS-1 metastasis-suppressor 0.926
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.921
Pax8 paired box gene 8 0.901
Esr2 estrogen receptor 2 (beta) 0.891
Ar androgen receptor 0.882
Myd88 myeloid differentiation primary response gene 88 0.879
Pten phosphatase and tensin homolog 0.874
Fgf10 fibroblast growth factor 10 0.856
Cbl Casitas B-lineage lymphoma 0.856
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.803
Cry2 cryptochrome 2 (photolyase-like) 0.802
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 0.790
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.782
Pax2 paired box gene 2 0.772
Grb10 growth factor receptor bound protein 10 0.771
Rarg retinoic acid receptor, gamma 0.756
Pitx1 paired-like homeodomain transcription factor 1 0.723
Insr insulin receptor 0.700
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.684
Lep leptin 0.666
Tgfb1 transforming growth factor, beta 1 0.643
Rnf2 ring finger protein 2 0.633
Pbx1 pre B-cell leukemia transcription factor 1 0.614
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.613
Trim28 tripartite motif-containing 28 0.610
Cyld cylindromatosis (turban tumor syndrome) 0.598
Gnrhr gonadotropin releasing hormone receptor 0.589
Ednra endothelin receptor type A 0.588
Prlr prolactin receptor 0.580
Mecom MDS1 and EVI1 complex locus 0.570
Per1 period homolog 1 (Drosophila) 0.565
Tlr2 toll-like receptor 2 0.556
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.554
Tbx3 T-box 3 0.548
Hoxa1 homeobox A1 0.531
Smad4 MAD homolog 4 (Drosophila) 0.523
Bglap bone gamma carboxyglutamate protein 0.521
Cry1 cryptochrome 1 (photolyase-like) 0.507
Snai1 snail homolog 1 (Drosophila) 0.488
Nos3 nitric oxide synthase 3, endothelial cell 0.467
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.452
Ighmbp2 immunoglobulin mu binding protein 2 0.445
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.442
Prox1 prospero-related homeobox 1 0.440
Myf5 myogenic factor 5 0.437
Map3k8 mitogen-activated protein kinase kinase kinase 8 0.436
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.436
Smad3 MAD homolog 3 (Drosophila) 0.431
Wt1 Wilms tumor 1 homolog 0.414
Hand1 heart and neural crest derivatives expressed transcript 1 0.413
Gsc goosecoid homeobox 0.401
Unc93b1 unc-93 homolog B1 (C. elegans) 0.395
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.389
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.383
Ddx60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.377
Igh immunoglobulin heavy chain complex 0.370
Tlr4 toll-like receptor 4 0.370
Nodal nodal 0.362
Gata4 GATA binding protein 4 0.358
Gdf3 growth differentiation factor 3 0.356
Pou4f2 POU domain, class 4, transcription factor 2 0.350
Socs1 suppressor of cytokine signaling 1 0.349
Kdm2b lysine (K)-specific demethylase 2B 0.345
Csf1 colony stimulating factor 1 (macrophage) 0.343
Ptf1a pancreas specific transcription factor, 1a 0.342
Cdx2 caudal type homeobox 2 0.337
Esrrb estrogen related receptor, beta 0.333
Nos2 nitric oxide synthase 2, inducible 0.331
Ncoa6 nuclear receptor coactivator 6 0.331
Rac1 RAS-related C3 botulinum substrate 1 0.329
Foxa2 forkhead box A2 0.328
Ret ret proto-oncogene 0.322
Vdr vitamin D receptor 0.321
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.319
Cd44 CD44 antigen 0.315
Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 0.308
Ncoa1 nuclear receptor coactivator 1 0.298
Axl AXL receptor tyrosine kinase 0.296
Nr0b1 nuclear receptor subfamily 0, group B, member 1 0.294
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.289
Rarb retinoic acid receptor, beta 0.287
Adam17 a disintegrin and metallopeptidase domain 17 0.279
Timp1 tissue inhibitor of metalloproteinase 1 0.278
Pnpla2 patatin-like phospholipase domain containing 2 0.276
Notch2 Notch gene homolog 2 (Drosophila) 0.276
Egr2 early growth response 2 0.272
Ncor1 nuclear receptor co-repressor 1 0.264
Nos1 nitric oxide synthase 1, neuronal 0.261
Tef thyrotroph embryonic factor 0.261
Sfrp2 secreted frizzled-related protein 2 0.259
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
eya-1 Protein EYA-1 0.290
egl-18 Protein EGL-18 0.271
Y44E3A.6 Protein Y44E3A.6 0.227
skp-1 Protein SKP-1 0.212
unc-37 Protein UNC-37 0.193
lbp-3 Protein LBP-3 0.160
unc-40 Protein UNC-40 0.157
dpf-7 Protein DPF-7 0.148
dnj-19 Protein DNJ-19 0.145
tam-1 Protein TAM-1 0.141
hel-1 Protein HEL-1 0.139
daf-21 Protein DAF-21 0.134
nhr-130 Protein NHR-130 0.134
epn-1 Protein EPN-1 0.134
pry-1 Protein PRY-1 0.123
dcr-1 Protein DCR-1 0.121
zag-1 Protein ZAG-1 0.117
rpt-4 Protein RPT-4 0.116
attf-2 Protein ATTF-2 0.114
hpo-22 Protein HPO-22 0.112
unc-86 Protein UNC-86 0.100
hbl-1 Protein HBL-1 0.098
C30C11.4 Protein C30C11.4 0.096
nhr-32 Protein NHR-32 0.095
CELE_Y73F8A.25 Protein Y73F8A.25 0.092
tba-1 Protein TBA-1 0.092
lin-66 Protein LIN-66 0.088
ahr-1 Protein AHR-1 0.088
CELE_ZK1240.3 Protein ZK1240.3 0.086
piga-1 Protein PIGA-1 0.083
rpt-3 Protein RPT-3 0.080
lit-1 Protein LIT-1 0.078
aakg-2 Protein AAKG-2 0.077
let-418 Protein LET-418 0.076
trr-1 Protein TRR-1 0.076
afd-1 Protein AFD-1 0.075
gei-4 Protein GEI-4 0.075
pop-1 Protein POP-1 0.073
lin-17 Protein LIN-17 0.073
atg-2 Protein ATG-2 0.073
R11A8.7 Protein R11A8.7 0.072
sax-7 Protein SAX-7 0.068
cchl-1 Protein CCHL-1 0.068
CELE_C10C6.6 Protein C10C6.6 0.066
zfp-1 Protein ZFP-1 0.064
capg-1 Protein CAPG-1 0.064
sago-1 Protein SAGO-1 0.061
tbb-2 Protein TBB-2 0.060
mec-1 Protein MEC-1 0.060
cpsf-2 Protein CPSF-2 0.058
dnj-13 Protein DNJ-13 0.057
pas-6 Protein PAS-6 0.056
cey-1 Protein CEY-1 0.055
hrpf-1 Protein HRPF-1 0.055
sek-1 Protein SEK-1 0.055
ain-2 Protein AIN-2 0.054
ZK593.3 Protein ZK593.3 0.053
alx-1 Protein ALX-1 0.053
nra-3 Protein NRA-3 0.053
elo-6 Protein ELO-6 0.053
taf-4 Protein TAF-4 0.052
mig-38 Protein MIG-38 0.052
die-1 Protein DIE-1 0.052
npp-2 Protein NPP-2 0.052
CELE_Y105E8B.7 Protein Y105E8B.7 0.052
cyd-1 Protein CYD-1 0.052
ceh-16 Protein CEH-16 0.051
F28B3.1 Protein F28B3.1 0.051
eor-2 Protein EOR-2 0.051
eftu-2 Protein EFTU-2 0.051
dmd-7 Protein DMD-7 0.050
tomm-40 Protein TOMM-40 0.050
ant-1.1 Protein ANT-1.1 0.050
F10D7.5 Protein F10D7.5 0.050
egl-30 Protein EGL-30 0.050
eif-3.K Protein EIF-3.K 0.050
acdh-3 Protein ACDH-3 0.050
gsp-2 Protein GSP-2 0.049
tag-275 Protein TAG-275 0.049
lbp-5 Protein LBP-5 0.049
K10C9.3 Protein K10C9.3 0.049
egl-5 Protein EGL-5 0.049
F54D8.6 Protein F54D8.6 0.048
C35D10.6 Protein C35D10.6 0.048
ire-1 Protein IRE-1 0.048
pqn-21 Protein PQN-21 0.048
nud-2 Protein NUD-2 0.048
Y17G7B.20 Protein Y17G7B.20 0.047
ccr-4 Protein CCR-4 0.047
fox-1 Protein FOX-1 0.047
rpn-10 Protein RPN-10 0.046
knl-2 Protein KNL-2 0.046
tag-303 Protein TAG-303 0.046
rpt-2 Protein RPT-2 0.045
heh-1 Protein HEH-1 0.045
fli-1 Protein FLI-1 0.045
sna-2 Protein SNA-2 0.045
lin-36 Protein LIN-36 0.044
F15D3.7 Protein F15D3.7 0.044
rsp-6 Protein RSP-6 0.044
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Danio rerio
Name Description Probability Func Analog Organism
crabp2a cellular retinoic acid binding protein 2, a 0.956
esr2a estrogen receptor 2a 0.618
raraa retinoic acid receptor, alpha a 0.533
nr1d2b nuclear receptor subfamily 1, group D, member 2b 0.400
rarab retinoic acid receptor, alpha b 0.397
vdra vitamin D receptor a 0.383
nod1 nucleotide-binding oligomerization domain containing 1 0.358
per2 period homolog 2 (Drosophila) 0.357
plekhg4 pleckstrin homology domain containing, family G (with RhoGef domain) member 4 0.357
rdh10a retinol dehydrogenase 10a 0.339
hspa4a heat shock protein 4a 0.311
thrab thyroid hormone receptor alpha b 0.303
cyp1a cytochrome P450, family 1, subfamily A 0.285
rag1 recombination activating gene 1 0.266
hoxb2a homeo box B2a 0.242
esr1 estrogen receptor 1 0.239
pparg peroxisome proliferator activated receptor gamma 0.235
dlc deltaC 0.227
lratb lecithin retinol acyltransferase b (phosphatidylcholine--retinol O-acyltransferase b) 0.226
nr2f1a nuclear receptor subfamily 2, group F, member 1a 0.218
efnb3b ephrin B3b 0.215
hspd1 heat shock 60kD protein 1 (chaperonin) 0.210
clock clock 0.202
rxraa retinoid X receptor, alpha a 0.192
sox7 SRY-box containing gene 7 0.190
sox11a SRY-box containing gene 11a 0.184
hoxb1b homeo box B1b 0.178
hoxc4a homeo box C4a 0.177
nr5a5 nuclear receptor subfamily 5, group A, member 5 0.174
fzd5 frizzled homolog 5 0.161
aqp8a.1 aquaporin 8a, tandem duplicate 1 0.161
rarga retinoic acid receptor gamma a 0.156
hoxa4a homeo box A4a 0.152
gli2a GLI-Kruppel family member GLI2a 0.151
axin2 axin 2 (conductin, axil) 0.149
bmp15 bone morphogenetic protein 15 0.148
fsta follistatin a 0.147
pou1f1 POU domain, class 1, transcription factor 1 0.145
gata5 GATA-binding protein 5 0.144
kdrl kinase insert domain receptor like 0.141
rxrba retinoid x receptor, beta a 0.140
gbx1 gastrulation brain homeobox 1 0.139
acta2 actin, alpha 2, smooth muscle, aorta 0.137
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.128
kctd15a potassium channel tetramerisation domain containing 15a 0.126
hnf1ba HNF1 homeobox Ba 0.124
ncoa2 nuclear receptor coactivator 2 0.119
gdf11 growth differentiation factor 11 0.118
hspa9 heat shock protein 9 0.116
edn1 endothelin 1 0.115
vax1 ventral anterior homeobox 1 0.110
ptgs2a prostaglandin-endoperoxide synthase 2a 0.110
onecut1 one cut domain, family member 1 0.110
akap12b A kinase (PRKA) anchor protein (gravin) 12b 0.109
aldh2a aldehyde dehydrogenase 2 family (mitochondrial)a 0.105
bhlhe40 basic helix-loop-helix family, member e40 0.103
tead3a TEA domain family member 3 a 0.101
esr2b estrogen receptor 2b 0.097
hoxa1a homeo box A1a 0.095
meis1 myeloid ecotropic viral integration 1 0.095
nr5a1b nuclear receptor subfamily 5, group A, member 1b 0.094
hdac3 histone deacetylase 3 0.094
foxa3 forkhead box A3 0.093
fgfrl1b fibroblast growth factor receptor-like 1b 0.090
thrb thyroid hormone receptor beta 0.090
si:dkey-228g21.4 si:dkey-228g21.4 0.089
nr5a2 nuclear receptor subfamily 5, group A, member 2 0.088
pou3f2 POU class 3 homeobox 2 0.088
pdx1 pancreatic and duodenal homeobox 1 0.087
LOC565839 tumor necrosis factor alpha-induced protein 2-like 0.086
robo3 roundabout homolog 3 0.083
dct dopachrome tautomerase 0.082
znf395b zinc finger protein 395b 0.082
rxrbb retinoid x receptor, beta b 0.081
tal1 T-cell acute lymphocytic leukemia 1 0.080
sb:cb81 sb:cb81 0.080
meis2.1 myeloid ecotropic viral integration site 2.1 0.077
frem3 Fras1 related extracellular matrix 3 0.076
ptf1a pancreas specific transcription factor, 1a 0.076
jam3b junctional adhesion molecule 3b 0.076
foxb1.2 forkhead box B1.2 0.076
sfrp5 secreted frizzled-related protein 5 0.074
zff9 zinc finger protein 9 0.071
foxb1.1 forkhead box B1.1 0.071
tp53 tumor protein p53 0.069
caprin1a cell cycle associated protein 1a 0.069
neo1 neogenin 1 0.069
nkx2.3 NK2 transcription factor related 3 0.069
dio2 deiodinase, iodothyronine, type II 0.068
nr0b1 nuclear receptor subfamily 0, group B, member 1 0.066
lfng lunatic fringe homolog 0.066
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.066
fabp11a fatty acid binding protein 11a 0.065
ca2 carbonic anhydrase II 0.064
shhb sonic hedgehog b 0.064
gdf6a growth differentiation factor 6a 0.064
cyp11a1 cytochrome P450, subfamily XIA, polypeptide 1 0.062
myf5 myogenic factor 5 0.061
hoxb1a homeo box B1a 0.061
esrrb estrogen-related receptor beta 0.056
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Drosophila melanogaster
Name Description Probability Func Analog Organism
brm brahma 0.322
Hop Hsp70/Hsp90 organizing protein homolog 0.249
lwr lesswright 0.216
hkl hook-like 0.185
Su(var)2-10 Suppressor of variegation 2-10 0.178
tll tailless 0.145
Iswi Imitation SWI 0.076
Trh Tryptophan hydroxylase 0.073
fru fruitless 0.068
CkIIbeta Casein kinase II beta subunit 0.061
pan pangolin 0.058
scny scrawny 0.058
Snr1 Snf5-related 1 0.057
Chro Chromator 0.052
Nipped-A CG33554 gene product from transcript CG33554-RE 0.050
ebi CG4063 gene product from transcript CG4063-RA 0.049
Nlp Nucleoplasmin 0.048
CG10103 CG10103 gene product from transcript CG10103-RA 0.047
ftz-f1 ftz transcription factor 1 0.047
esg escargot 0.039
byn brachyenteron 0.037
InR Insulin-like receptor 0.037
Clk Clock 0.036
Dref DNA replication-related element factor 0.035
Hrb98DE Heterogeneous nuclear ribonucleoprotein at 98DE 0.035
nej nejire 0.035
ash1 absent, small, or homeotic discs 1 0.034
Rpd3 CG7471 gene product from transcript CG7471-RA 0.034
arr arrow 0.034
usp ultraspiracle 0.033
kis kismet 0.032
gcm glial cells missing 0.032
wapl wings apart-like 0.031
Scm Sex comb on midleg 0.030
woc without children 0.030
inx7 innexin 7 0.029
mxc multi sex combs 0.028
ey eyeless 0.028
rib ribbon 0.027
eve even skipped 0.027
Nacalpha Nascent polypeptide associated complex protein alpha subunit 0.026
fas faint sausage 0.026
CG4857 CG4857 gene product from transcript CG4857-RD 0.024
CG16778 CG16778 gene product from transcript CG16778-RA 0.024
vri vrille 0.024
Df31 Decondensation factor 31 0.024
Dek CG5935 gene product from transcript CG5935-RA 0.023
nos nanos 0.023
sens senseless 0.023
Cam Calmodulin 0.022
dco discs overgrown 0.021
disco disconnected 0.021
Gdi GDP dissociation inhibitor 0.021
Usp7 ubiquitin-specific protease 7 0.021
Kap-alpha3 karyopherin alpha3 0.020
nmo nemo 0.020
Psi P-element somatic inhibitor 0.020
cnc cap-n-collar 0.019
Akt1 CG4006 gene product from transcript CG4006-RA 0.019
cyc cycle 0.019
Nup50 Nucleoporin 50 0.019
Cul-3 Cullin-3 0.019
CG11267 CG11267 gene product from transcript CG11267-RA 0.019
dom domino 0.019
hth homothorax 0.018
Rm62 CG10279 gene product from transcript CG10279-RD 0.018
Mp20 Muscle protein 20 0.018
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.017
Phm Peptidylglycine-alpha-hydroxylating monooxygenase 0.017
dac dachshund 0.017
sro shroud 0.017
cpo couch potato 0.017
hkb huckebein 0.017
Pen Pendulin 0.016
bs blistered 0.016
CG34400 CG34400 gene product from transcript CG34400-RD 0.016
SmD3 Small ribonucleoprotein particle protein SmD3 0.016
Caf1 Chromatin assembly factor 1 subunit 0.016
tim timeless 0.016
Smr Smrter 0.016
CG5177 CG5177 gene product from transcript CG5177-RA 0.016
Hsf Heat shock factor 0.016
Dat Dopamine N acetyltransferase 0.015
CG32685 CG32685 gene product from transcript CG32685-RC 0.015
bin biniou 0.015
CG9007 CG9007 gene product from transcript CG9007-RA 0.015
bnl branchless 0.015
sno strawberry notch 0.015
Ork1 Open rectifier K[+] channel 1 0.015
crol crooked legs 0.015
retn retained 0.014
ftz fushi tarazu 0.014
ap apterous 0.014
mub mushroom-body expressed 0.014
Tsc1 CG6147 gene product from transcript CG6147-RA 0.014
Gip GIP-like 0.014
Cirl CG8639 gene product from transcript CG8639-RC 0.013
CG10650 CG10650 gene product from transcript CG10650-RA 0.013
B-H2 BarH2 0.013
drpr draper 0.013
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Homo sapiens
Name Description Probability Func Analog Organism
ESR1 estrogen receptor 1 1.000
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 1.000
RARA retinoic acid receptor, alpha 1.000
CREBBP CREB binding protein 1.000
RXRA retinoid X receptor, alpha 1.000
NCOA1 nuclear receptor coactivator 1 0.999
AR androgen receptor 0.999
EP300 E1A binding protein p300 0.998
TP53 tumor protein p53 0.992
MED1 mediator complex subunit 1 0.990
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.989
SMAD4 SMAD family member 4 0.989
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.979
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.976
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.974
SIRT1 sirtuin 1 0.971
NCOA3 nuclear receptor coactivator 3 0.967
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.967
NCOR2 nuclear receptor corepressor 2 0.963
HDAC1 histone deacetylase 1 0.951
NCOA6 nuclear receptor coactivator 6 0.935
ATXN1 ataxin 1 0.932
NCOA2 nuclear receptor coactivator 2 0.926
MED15 mediator complex subunit 15 0.915
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.911
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.905
SP1 Sp1 transcription factor 0.904
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.895
MED12 mediator complex subunit 12 0.877
SMAD3 SMAD family member 3 0.853
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.837
EGFR epidermal growth factor receptor 0.818
CDK19 cyclin-dependent kinase 19 0.809
NCOR1 nuclear receptor corepressor 1 0.807
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.800
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.799
PML promyelocytic leukemia 0.795
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2 0.785
MED25 mediator complex subunit 25 0.728
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.723
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.721
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.717
QKI quaking homolog, KH domain RNA binding (mouse) 0.710
SPOP speckle-type POZ protein 0.708
HNF4A hepatocyte nuclear factor 4, alpha 0.662
STAT1 signal transducer and activator of transcription 1, 91kDa 0.646
SKIL SKI-like oncogene 0.603
ARID1B AT rich interactive domain 1B (SWI1-like) 0.599
CDK8 cyclin-dependent kinase 8 0.598
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.591
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.588
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.580
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 0.553
MED29 mediator complex subunit 29 0.552
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 0.547
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.545
RB1 retinoblastoma 1 0.543
AHR aryl hydrocarbon receptor 0.518
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.514
BIRC3 baculoviral IAP repeat containing 3 0.473
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.448
IFIH1 interferon induced with helicase C domain 1 0.445
NRIP1 nuclear receptor interacting protein 1 0.432
MED13 mediator complex subunit 13 0.432
RBPMS RNA binding protein with multiple splicing 0.429
ZHX1 zinc fingers and homeoboxes 1 0.423
SMAD9 SMAD family member 9 0.413
GSK3B glycogen synthase kinase 3 beta 0.403
TRAF6 TNF receptor-associated factor 6 0.401
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.401
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.399
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.389
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.388
RORA RAR-related orphan receptor A 0.387
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.384
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.378
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.373
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.364
C16orf53 chromosome 16 open reading frame 53 0.360
MTA1 metastasis associated 1 0.351
SKP1 S-phase kinase-associated protein 1 0.350
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 0.338
MAP3K1 mitogen-activated protein kinase kinase kinase 1 0.329
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 0.324
KAT2B K(lysine) acetyltransferase 2B 0.322
VEZF1 vascular endothelial zinc finger 1 0.321
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.320
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.319
LDB1 LIM domain binding 1 0.307
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.307
MYD88 myeloid differentiation primary response gene (88) 0.304
BAZ1A bromodomain adjacent to zinc finger domain, 1A 0.303
PPID peptidylprolyl isomerase D 0.301
ESRRG estrogen-related receptor gamma 0.295
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.294
EPAS1 endothelial PAS domain protein 1 0.290
ESR2 estrogen receptor 2 (ER beta) 0.290
EED embryonic ectoderm development 0.286
SAMD9 sterile alpha motif domain containing 9 0.281
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.269
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Dbp D site of albumin promoter (albumin D-box) binding protein 0.384
Ahr aryl hydrocarbon receptor 0.324
Errfi1 ERBB receptor feedback inhibitor 1 0.306
Fkbp4 FK506 binding protein 4 0.252
Stip1 stress-induced phosphoprotein 1 0.229
Marcks myristoylated alanine rich protein kinase C substrate 0.139
Rara retinoic acid receptor, alpha 0.136
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.110
Flt1 FMS-related tyrosine kinase 1 0.106
Nfib nuclear factor I/B 0.094
Cryaa crystallin, alpha A 0.091
Met met proto-oncogene 0.084
Pyy peptide YY (mapped) 0.077
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.077
Pim3 pim-3 oncogene 0.077
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.070
Il1r1 interleukin 1 receptor, type I 0.068
Synpo synaptopodin 0.066
Slc1a2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.061
Fam65a family with sequence similarity 65, member A 0.061
Prdm2 PR domain containing 2, with ZNF domain 0.051
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.051
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.049
Stat6 signal transducer and activator of transcription 6 0.048
Vipr1 vasoactive intestinal peptide receptor 1 0.046
Ar androgen receptor 0.046
Tert telomerase reverse transcriptase 0.045
Nfat5 nuclear factor of activated T-cells 5 0.044
Apba3 amyloid beta (A4) precursor protein-binding, family A, member 3 0.043
Tp53 tumor protein p53 0.039
Olr1362 olfactory receptor 1362 0.038
Trib1 tribbles homolog 1 (Drosophila) 0.038
Tgfbr2 transforming growth factor, beta receptor II 0.038
Ralgds ral guanine nucleotide dissociation stimulator 0.037
Prkch protein kinase C, eta 0.037
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.037
Hlf hepatic leukemia factor 0.035
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.035
Ddr2 discoidin domain receptor tyrosine kinase 2 0.034
Chordc1 cysteine and histidine-rich domain (CHORD)-containing 1 0.034
Mef2d myocyte enhancer factor 2D 0.034
Zfp37 zinc finger protein 37 0.034
Nr2f2 nuclear receptor subfamily 2, group F, member 2 0.033
Gfra2 GDNF family receptor alpha 2 0.033
Scnn1b sodium channel, nonvoltage-gated 1, beta 0.033
Il6st interleukin 6 signal transducer 0.032
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.032
Ldb1 LIM domain binding 1 0.031
Irf1 interferon regulatory factor 1 0.031
Creb1 cAMP responsive element binding protein 1 0.030
Fgd4 FYVE, RhoGEF and PH domain containing 4 0.030
Ncor1 nuclear receptor co-repressor 1 0.030
Abcc6 ATP-binding cassette, subfamily C (CFTR/MRP), member 6 0.029
Pip prolactin induced protein 0.029
Oaz3 ornithine decarboxylase antizyme 3 0.029
Gna11 guanine nucleotide binding protein, alpha 11 0.028
Il13ra2 interleukin 13 receptor, alpha 2 0.028
Hsph1 heat shock 105/110 protein 1 0.027
Cd4 Cd4 molecule 0.027
Ptger4 prostaglandin E receptor 4 (subtype EP4) 0.027
Ddr1 discoidin domain receptor tyrosine kinase 1 0.027
Gnai2 guanine nucleotide binding protein (G protein), alpha inhibiting 2 0.027
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.027
Zfp36 zinc finger protein 36 0.027
Myt1l myelin transcription factor 1-like 0.027
P2ry4 pyrimidinergic receptor P2Y, G-protein coupled, 4 0.026
Znf76 zinc finger protein 76 (expressed in testis) 0.026
Hsf1 heat shock transcription factor 1 0.026
Colec12 collectin sub-family member 12 0.026
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.026
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.026
Ptprc protein tyrosine phosphatase, receptor type, C 0.026
Mos Moloney sarcoma oncogene 0.026
Olr837 olfactory receptor 837 0.025
St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.025
Ptafr platelet-activating factor receptor 0.025
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.025
Cfp complement factor properdin 0.025
Rnase1 ribonuclease, RNase A family, 1 (pancreatic) 0.025
Syt9 synaptotagmin IX 0.025
Fam126b family with sequence similarity 126, member B 0.025
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.025
Gulo gulonolactone (L-) oxidase 0.025
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.025
Phax phosphorylated adaptor for RNA export 0.024
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.024
Il1b interleukin 1 beta 0.024
Mettl7b methyltransferase like 7B 0.024
Calm2 calmodulin 2 0.023
Klf6 Kruppel-like factor 6 0.023
Calcrl calcitonin receptor-like 0.023
Zfp362 zinc finger protein 362 0.023
Gsk3a glycogen synthase kinase 3 alpha 0.023
Emr1 EGF-like module containing, mucin-like, hormone receptor-like 1 0.023
Slc22a6 solute carrier family 22 (organic anion transporter), member 6 0.023
Phka1 phosphorylase kinase, alpha 1 0.023
Icam1 intercellular adhesion molecule 1 0.023
Nos2 nitric oxide synthase 2, inducible 0.023
Mylk2 myosin light chain kinase 2 0.023
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.023
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism