The network for 'positive regulation of secondary heart field cardioblast proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of secondary heart field cardioblast proliferation

Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).

Name Description Probability Func Analog Organism
Eya1 eyes absent 1 homolog (Drosophila) 1.000
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 1.000
Shh sonic hedgehog 1.000
Pitx2 paired-like homeodomain transcription factor 2 1.000
Tbx1 T-box 1 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Hoxa1 homeobox A1 1.000
Pax3 paired box gene 3 1.000
Foxg1 forkhead box G1 1.000
Pax2 paired box gene 2 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 1.000
Tcfap2a transcription factor AP-2, alpha 1.000
Fgf8 fibroblast growth factor 8 1.000
Msx1 homeobox, msh-like 1 1.000
Prrx1 paired related homeobox 1 1.000
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 1.000
Foxc2 forkhead box C2 1.000
Fgf10 fibroblast growth factor 10 1.000
Dlx5 distal-less homeobox 5 0.999
Gli3 GLI-Kruppel family member GLI3 0.999
Foxc1 forkhead box C1 0.999
Hand2 heart and neural crest derivatives expressed transcript 2 0.999
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.998
Pitx1 paired-like homeodomain transcription factor 1 0.997
Rarg retinoic acid receptor, gamma 0.997
Tbx3 T-box 3 0.996
Hand1 heart and neural crest derivatives expressed transcript 1 0.996
Bmp4 bone morphogenetic protein 4 0.996
Chd7 chromodomain helicase DNA binding protein 7 0.995
Gsc goosecoid homeobox 0.995
Gbx2 gastrulation brain homeobox 2 0.994
Sox2 SRY-box containing gene 2 0.993
Hoxa2 homeobox A2 0.991
Jag1 jagged 1 0.991
Isl1 ISL1 transcription factor, LIM/homeodomain 0.986
Hoxa3 homeobox A3 0.981
Sox9 SRY-box containing gene 9 0.959
Msx2 homeobox, msh-like 2 0.957
Bmp7 bone morphogenetic protein 7 0.951
Chrd chordin 0.949
Lmx1a LIM homeobox transcription factor 1 alpha 0.948
Rarb retinoic acid receptor, beta 0.948
Pax6 paired box gene 6 0.941
Nog noggin 0.940
Prrx2 paired related homeobox 2 0.934
Gata3 GATA binding protein 3 0.934
Emx2 empty spiracles homolog 2 (Drosophila) 0.925
Hoxa13 homeobox A13 0.924
Zeb1 zinc finger E-box binding homeobox 1 0.898
Vangl2 vang-like 2 (van gogh, Drosophila) 0.897
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.892
Smo smoothened homolog (Drosophila) 0.887
Six2 sine oculis-related homeobox 2 homolog (Drosophila) 0.875
Pax9 paired box gene 9 0.874
Hmx3 H6 homeobox 3 0.873
Lef1 lymphoid enhancer binding factor 1 0.845
Otx1 orthodenticle homolog 1 (Drosophila) 0.822
Ednra endothelin receptor type A 0.821
Fgf3 fibroblast growth factor 3 0.817
Hoxd3 homeobox D3 0.802
Vegfa vascular endothelial growth factor A 0.800
Sall4 sal-like 4 (Drosophila) 0.777
Hoxb3 homeobox B3 0.767
Dlx2 distal-less homeobox 2 0.761
Alx1 ALX homeobox 1 0.754
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.751
Runx2 runt related transcription factor 2 0.748
Bdnf brain derived neurotrophic factor 0.745
Pbx1 pre B-cell leukemia transcription factor 1 0.738
Wt1 Wilms tumor 1 homolog 0.725
Alx4 aristaless-like homeobox 4 0.706
Hoxa10 homeobox A10 0.684
Snai1 snail homolog 1 (Drosophila) 0.667
Fgfr1 fibroblast growth factor receptor 1 0.666
Tbx15 T-box 15 0.657
Hoxa11 homeobox A11 0.647
Hes1 hairy and enhancer of split 1 (Drosophila) 0.645
Dlx1 distal-less homeobox 1 0.623
Wnt3a wingless-related MMTV integration site 3A 0.621
Smad6 MAD homolog 6 (Drosophila) 0.618
Lhx1 LIM homeobox protein 1 0.612
Hoxd11 homeobox D11 0.595
Hoxb4 homeobox B4 0.590
Tbx5 T-box 5 0.573
Tgfb2 transforming growth factor, beta 2 0.535
Trp63 transformation related protein 63 0.531
Zic3 zinc finger protein of the cerebellum 3 0.512
Myf5 myogenic factor 5 0.502
Dlx6 distal-less homeobox 6 0.492
Gata4 GATA binding protein 4 0.482
Hoxd1 homeobox D1 0.475
Gata6 GATA binding protein 6 0.474
Tlx3 T-cell leukemia, homeobox 3 0.472
Wnt1 wingless-related MMTV integration site 1 0.461
Efna2 ephrin A2 0.449
Tcf21 transcription factor 21 0.439
Rara retinoic acid receptor, alpha 0.430
Pax8 paired box gene 8 0.420
Rxra retinoid X receptor alpha 0.416
En1 engrailed 1 0.408
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism