The network for 'polysaccharide biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

polysaccharide biosynthetic process

The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.

Mus musculus
Name Description Probability Func Analog Organism
Insr insulin receptor 0.991
Cry2 cryptochrome 2 (photolyase-like) 0.731
Nos3 nitric oxide synthase 3, endothelial cell 0.666
Igf1r insulin-like growth factor I receptor 0.619
Lepr leptin receptor 0.610
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.597
Grb10 growth factor receptor bound protein 10 0.570
Ghr growth hormone receptor 0.478
Irs2 insulin receptor substrate 2 0.401
Ins2 insulin II 0.294
Esr1 estrogen receptor 1 (alpha) 0.243
Akt1 thymoma viral proto-oncogene 1 0.186
Per1 period homolog 1 (Drosophila) 0.176
Rxra retinoid X receptor alpha 0.169
Thra thyroid hormone receptor alpha 0.169
Tef thyrotroph embryonic factor 0.155
Pim1 proviral integration site 1 0.137
Rarb retinoic acid receptor, beta 0.124
Egfr epidermal growth factor receptor 0.123
Per2 period homolog 2 (Drosophila) 0.116
Rarg retinoic acid receptor, gamma 0.114
Vegfa vascular endothelial growth factor A 0.110
Skp1a S-phase kinase-associated protein 1A 0.105
Igf2r insulin-like growth factor 2 receptor 0.105
Lep leptin 0.103
Pim3 proviral integration site 3 0.095
Thrb thyroid hormone receptor beta 0.080
Vdr vitamin D receptor 0.079
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.079
Nos1 nitric oxide synthase 1, neuronal 0.075
Pparg peroxisome proliferator activated receptor gamma 0.074
Pax8 paired box gene 8 0.072
Irs1 insulin receptor substrate 1 0.066
Drd2 dopamine receptor D2 0.065
Csf1 colony stimulating factor 1 (macrophage) 0.064
Dbp D site albumin promoter binding protein 0.063
Clock circadian locomotor output cycles kaput 0.060
Bmper BMP-binding endothelial regulator 0.058
Epn1 epsin 1 0.056
Duox2 dual oxidase 2 0.053
Pten phosphatase and tensin homolog 0.053
Igf2 insulin-like growth factor 2 0.053
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.053
Ar androgen receptor 0.052
Hoxa3 homeobox A3 0.048
Csnk1e casein kinase 1, epsilon 0.046
Pnpla2 patatin-like phospholipase domain containing 2 0.046
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.045
Tgfb2 transforming growth factor, beta 2 0.045
Slc27a1 solute carrier family 27 (fatty acid transporter), member 1 0.043
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit 0.042
Kl klotho 0.042
Cav1 caveolin 1, caveolae protein 0.042
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.042
Hrh1 histamine receptor H1 0.040
Lipe lipase, hormone sensitive 0.039
Ece1 endothelin converting enzyme 1 0.039
Usp2 ubiquitin specific peptidase 2 0.038
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.038
Capn1 calpain 1 0.038
Fshr follicle stimulating hormone receptor 0.037
Jak3 Janus kinase 3 0.036
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 0.036
Adam15 a disintegrin and metallopeptidase domain 15 (metargidin) 0.036
Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 0.034
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.033
Plxnd1 plexin D1 0.031
Acr acrosin prepropeptide 0.031
Nr1d1 nuclear receptor subfamily 1, group D, member 1 0.030
Stat5a signal transducer and activator of transcription 5A 0.029
Sh2b3 SH2B adaptor protein 3 0.029
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.029
Eya1 eyes absent 1 homolog (Drosophila) 0.029
Btrc beta-transducin repeat containing protein 0.029
Npc1 Niemann Pick type C1 0.029
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.028
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.028
Wnt9b wingless-type MMTV integration site 9B 0.027
Tgfbr2 transforming growth factor, beta receptor II 0.027
Ednra endothelin receptor type A 0.027
Nfic nuclear factor I/C 0.026
Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit 0.026
Igf1 insulin-like growth factor 1 0.025
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.023
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.023
Ctdsp2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.023
Tgfb1 transforming growth factor, beta 1 0.023
Hadh hydroxyacyl-Coenzyme A dehydrogenase 0.023
Tnks1bp1 tankyrase 1 binding protein 1 0.023
Socs1 suppressor of cytokine signaling 1 0.022
Mark4 MAP/microtubule affinity-regulating kinase 4 0.022
Stat5b signal transducer and activator of transcription 5B 0.022
Rps2 ribosomal protein S2 0.021
Htr3a 5-hydroxytryptamine (serotonin) receptor 3A 0.021
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.021
Agtr1a angiotensin II receptor, type 1a 0.020
Mapkapk2 MAP kinase-activated protein kinase 2 0.020
Twsg1 twisted gastrulation homolog 1 (Drosophila) 0.020
Akt2 thymoma viral proto-oncogene 2 0.019
Lhx4 LIM homeobox protein 4 0.019
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ext2 CG8433 gene product from transcript CG8433-RA 0.997
ttv tout-velu 0.526
Indy I'm not dead yet 0.434
CG5362 CG5362 gene product from transcript CG5362-RA 0.349
Zw Zwischenferment 0.195
botv brother of tout-velu 0.152
CG9485 CG9485 gene product from transcript CG9485-RD 0.146
Smox Smad on X 0.137
vri vrille 0.118
disp dispatched 0.092
myoglianin CG1838 gene product from transcript CG1838-RD 0.084
RhoL rho-like 0.070
Pgd Phosphogluconate dehydrogenase 0.070
Gs1 Glutamine synthetase 1 0.067
cbt cabut 0.057
sgl sugarless 0.052
Mo25 CG4083 gene product from transcript CG4083-RA 0.050
Got2 Glutamate oxaloacetate transaminase 2 0.050
ry rosy 0.048
Thiolase CG4581 gene product from transcript CG4581-RA 0.045
mys myospheroid 0.035
Bre1 CG10542 gene product from transcript CG10542-RA 0.034
sfl sulfateless 0.026
cher cheerio 0.023
Pgk Phosphoglycerate kinase 0.023
egh egghead 0.023
Gpdh Glycerol 3 phosphate dehydrogenase 0.020
CG10260 CG10260 gene product from transcript CG10260-RB 0.019
Zyx102EF CG32018 gene product from transcript CG32018-RA 0.019
CG32406 CG32406 gene product from transcript CG32406-RA 0.018
wun wunen 0.018
CG3597 CG3597 gene product from transcript CG3597-RA 0.017
dhd deadhead 0.016
sr stripe 0.016
CG15609 CG15609 gene product from transcript CG15609-RE 0.015
Akt1 CG4006 gene product from transcript CG4006-RA 0.014
Prat2 Phosphoribosylamidotransferase 2 0.014
rols rolling pebbles 0.013
spen split ends 0.012
vir virilizer 0.012
CG6904 CG6904 gene product from transcript CG6904-RC 0.011
hipk homeodomain interacting protein kinase 0.010
CkIalpha Casein kinase Ialpha 0.010
capt capulet 0.010
Pli Pellino 0.010
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Homo sapiens
Name Description Probability Func Analog Organism
INSR insulin receptor 0.989
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.988
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.972
GRB10 growth factor receptor-bound protein 10 0.938
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.879
PRKCZ protein kinase C, zeta 0.866
IRS1 insulin receptor substrate 1 0.823
IGF1R insulin-like growth factor 1 receptor 0.698
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.627
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.601
BCL3 B-cell CLL/lymphoma 3 0.547
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.429
NUMB numb homolog (Drosophila) 0.419
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.365
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.362
HIP1 huntingtin interacting protein 1 0.348
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.344
IRS2 insulin receptor substrate 2 0.317
NRP1 neuropilin 1 0.197
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.183
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.180
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.152
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.127
NOXA1 NADPH oxidase activator 1 0.123
LZTS2 leucine zipper, putative tumor suppressor 2 0.106
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.097
STAT5B signal transducer and activator of transcription 5B 0.095
THBS1 thrombospondin 1 0.093
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.092
IGF2R insulin-like growth factor 2 receptor 0.089
LAT linker for activation of T cells 0.089
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.088
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.087
ENG endoglin 0.085
SH2B1 SH2B adaptor protein 1 0.074
TOM1L1 target of myb1 (chicken)-like 1 0.071
ITGB1BP3 integrin beta 1 binding protein 3 0.070
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.069
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.066
PRKCB protein kinase C, beta 0.062
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.056
CNTF ciliary neurotrophic factor 0.053
LRRK2 leucine-rich repeat kinase 2 0.053
RAB6A RAB6A, member RAS oncogene family 0.051
PICK1 protein interacting with PRKCA 1 0.050
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.050
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.048
FAF1 Fas (TNFRSF6) associated factor 1 0.048
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.046
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.045
FSTL1 follistatin-like 1 0.044
SH3RF1 SH3 domain containing ring finger 1 0.044
TNIP2 TNFAIP3 interacting protein 2 0.039
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.038
RAB5A RAB5A, member RAS oncogene family 0.037
OCRL oculocerebrorenal syndrome of Lowe 0.036
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.035
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.035
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.035
DCAF7 DDB1 and CUL4 associated factor 7 0.034
HIPK2 homeodomain interacting protein kinase 2 0.034
MET met proto-oncogene (hepatocyte growth factor receptor) 0.033
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.033
EGFR epidermal growth factor receptor 0.033
MAPT microtubule-associated protein tau 0.033
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.033
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.032
LDLR low density lipoprotein receptor 0.030
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.028
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.028
RPTOR regulatory associated protein of MTOR, complex 1 0.027
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme 0.026
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.026
SESN2 sestrin 2 0.025
INPPL1 inositol polyphosphate phosphatase-like 1 0.023
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.022
NMT2 N-myristoyltransferase 2 0.022
CAPRIN2 caprin family member 2 0.022
CDCP1 CUB domain containing protein 1 0.022
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.022
RAB14 RAB14, member RAS oncogene family 0.021
COL6A1 collagen, type VI, alpha 1 0.021
EPS15 epidermal growth factor receptor pathway substrate 15 0.021
SORBS2 sorbin and SH3 domain containing 2 0.021
PTPRB protein tyrosine phosphatase, receptor type, B 0.020
PRKCA protein kinase C, alpha 0.020
OSBP oxysterol binding protein 0.019
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.019
CUX1 cut-like homeobox 1 0.018
GCKR glucokinase (hexokinase 4) regulator 0.018
COL5A1 collagen, type V, alpha 1 0.018
DCTN1 dynactin 1 0.018
PFKL phosphofructokinase, liver 0.017
PPID peptidylprolyl isomerase D 0.017
NCF1 neutrophil cytosolic factor 1 0.017
A2M alpha-2-macroglobulin 0.016
GRB14 growth factor receptor-bound protein 14 0.016
COL4A2 collagen, type IV, alpha 2 0.016
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma 0.016
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.016
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Rattus norvegicus
Name Description Probability Func Analog Organism
Etfdh electron-transferring-flavoprotein dehydrogenase 0.046
Acadl acyl-Coenzyme A dehydrogenase, long-chain 0.034
Pgm1 phosphoglucomutase 1 0.026
Acox1 acyl-Coenzyme A oxidase 1, palmitoyl 0.021
Syngr2 synaptogyrin 2 0.021
Fez2 fasciculation and elongation protein zeta 2 (zygin II) 0.020
Pfn1 profilin 1 0.020
Hadhb hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit 0.020
Ugp2 UDP-glucose pyrophosphorylase 2 0.018
Snrpb small nuclear ribonucleoprotein polypeptides B and B1 0.014
Eif3f eukaryotic translation initiation factor 3, subunit F 0.013
Decr1 2,4-dienoyl CoA reductase 1, mitochondrial 0.013
Eef2 eukaryotic translation elongation factor 2 0.013
Hist1h1a histone cluster 1, H1a 0.013
Hsd17b4 hydroxysteroid (17-beta) dehydrogenase 4 0.012
Aldoa aldolase A, fructose-bisphosphate 0.012
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.012
Etfa electron-transfer-flavoprotein, alpha polypeptide 0.011
Rab1b RAB1B, member RAS oncogene family 0.011
Serinc1 serine incorporator 1 0.010
Aprt adenine phosphoribosyl transferase 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GSY2 Gsy2p 0.988
GLG2 Glg2p 0.906
GPH1 Gph1p 0.751
GSY1 Gsy1p 0.748
PIG2 Pig2p 0.714
UGP1 Ugp1p 0.699
RHO1 Rho1p 0.639
SLT2 Slt2p 0.632
CBK1 Cbk1p 0.545
CHS5 Chs5p 0.526
GLC7 Glc7p 0.520
GIP2 Gip2p 0.519
GDB1 Gdb1p 0.479
BUD7 Bud7p 0.406
HXK1 Hxk1p 0.371
BCH2 Bch2p 0.362
MBR1 Mbr1p 0.341
MMR1 Mmr1p 0.310
CHS6 Chs6p 0.260
GLG1 Glg1p 0.260
RDI1 Rdi1p 0.258
CHS3 Chs3p 0.213
SLG1 Slg1p 0.201
ROT2 Rot2p 0.198
PCL10 Pcl10p 0.174
HXK2 Hxk2p 0.158
GAC1 Gac1p 0.152
YKR075C hypothetical protein 0.149
VHS1 Vhs1p 0.147
DBF2 Dbf2p 0.139
FKS1 Fks1p 0.130
CSR2 Csr2p 0.115
BST1 Bst1p 0.111
MIG2 Mig2p 0.111
HXT3 Hxt3p 0.109
BEM3 Bem3p 0.108
BEM2 Bem2p 0.103
NVJ1 Nvj1p 0.097
BMH2 Bmh2p 0.097
GLN3 Gln3p 0.093
MIG3 Mig3p 0.092
RIM15 Rim15p 0.091
NEM1 Nem1p 0.082
AGP2 Agp2p 0.077
ARP8 Arp8p 0.077
HOC1 Hoc1p 0.077
YDL073W hypothetical protein 0.077
YKL187C hypothetical protein 0.076
MIG1 Mig1p 0.073
PGM2 Pgm2p 0.072
LYS5 Lys5p 0.072
FMP48 Fmp48p 0.072
YNR014W hypothetical protein 0.072
SFL1 Sfl1p 0.071
HRR25 Hrr25p 0.071
RGS2 Rgs2p 0.069
FHL1 Fhl1p 0.068
PSK2 Psk2p 0.067
KIC1 Kic1p 0.066
VID24 Vid24p 0.064
TAO3 Tao3p 0.062
DAL81 Dal81p 0.061
HXT7 Hxt7p 0.060
VAC7 Vac7p 0.057
YGL242C hypothetical protein 0.057
DNF1 Dnf1p 0.056
TRS65 Trs65p 0.056
PTP3 Ptp3p 0.053
HKR1 Hkr1p 0.051
YCL042W hypothetical protein 0.050
YPL014W hypothetical protein 0.050
ICY1 Icy1p 0.050
GIS4 Gis4p 0.050
RLM1 Rlm1p 0.049
TGL5 Tgl5p 0.048
PNC1 Pnc1p 0.048
MPT5 Mpt5p 0.048
HAL5 Hal5p 0.048
NTO1 Nto1p 0.048
SLA2 Sla2p 0.046
EAR1 Ear1p 0.046
TSC3 Tsc3p 0.044
LRE1 Lre1p 0.043
BSC2 Bsc2p 0.042
CYK3 Cyk3p 0.042
KRE6 Kre6p 0.042
CCH1 Cch1p 0.042
YIL067C hypothetical protein 0.042
NGL3 Ngl3p 0.040
SAC7 Sac7p 0.040
HST3 Hst3p 0.040
YPR157W hypothetical protein 0.039
PGM1 Pgm1p 0.038
BCH1 Bch1p 0.038
PSK1 Psk1p 0.037
PKC1 Pkc1p 0.037
SBE22 Sbe22p 0.036
PRM5 Prm5p 0.036
MTL1 Mtl1p 0.036
PYK2 Pyk2p 0.036