The network for 'digestive system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

digestive system development

The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.

Mus musculus
Name Description Probability Func Analog Organism
Ctnnb1 catenin (cadherin associated protein), beta 1 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Shh sonic hedgehog 1.000
Smad4 MAD homolog 4 (Drosophila) 1.000
Nodal nodal 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Otx2 orthodenticle homolog 2 (Drosophila) 0.999
Pitx2 paired-like homeodomain transcription factor 2 0.999
Rarg retinoic acid receptor, gamma 0.999
Foxc1 forkhead box C1 0.998
Pax3 paired box gene 3 0.998
Fgfr1 fibroblast growth factor receptor 1 0.997
Pax6 paired box gene 6 0.996
Bmp4 bone morphogenetic protein 4 0.995
Zeb1 zinc finger E-box binding homeobox 1 0.992
Hand1 heart and neural crest derivatives expressed transcript 1 0.992
Lhx1 LIM homeobox protein 1 0.990
Tbx3 T-box 3 0.987
Msx1 homeobox, msh-like 1 0.987
Lef1 lymphoid enhancer binding factor 1 0.987
Smad6 MAD homolog 6 (Drosophila) 0.986
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.986
Vangl2 vang-like 2 (van gogh, Drosophila) 0.985
Sox2 SRY-box containing gene 2 0.984
Zic3 zinc finger protein of the cerebellum 3 0.983
Fgf8 fibroblast growth factor 8 0.983
Pax2 paired box gene 2 0.981
Tgfbr2 transforming growth factor, beta receptor II 0.980
Hoxa1 homeobox A1 0.980
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.972
Chd7 chromodomain helicase DNA binding protein 7 0.968
Smad3 MAD homolog 3 (Drosophila) 0.966
Isl1 ISL1 transcription factor, LIM/homeodomain 0.964
Emx1 empty spiracles homolog 1 (Drosophila) 0.963
Prrx1 paired related homeobox 1 0.959
Tgfb2 transforming growth factor, beta 2 0.955
Apc adenomatosis polyposis coli 0.948
Neurog3 neurogenin 3 0.946
Hmx3 H6 homeobox 3 0.944
Map3k7 mitogen-activated protein kinase kinase kinase 7 0.943
Lmx1b LIM homeobox transcription factor 1 beta 0.938
Fgf10 fibroblast growth factor 10 0.936
Gsk3b glycogen synthase kinase 3 beta 0.933
Efnb2 ephrin B2 0.930
Pou5f1 POU domain, class 5, transcription factor 1 0.928
Foxh1 forkhead box H1 0.924
Sall4 sal-like 4 (Drosophila) 0.922
Bcl2 B-cell leukemia/lymphoma 2 0.918
Gata4 GATA binding protein 4 0.918
Hes1 hairy and enhancer of split 1 (Drosophila) 0.918
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.915
Axin1 axin 1 0.910
Atoh7 atonal homolog 7 (Drosophila) 0.908
Wt1 Wilms tumor 1 homolog 0.907
Smad2 MAD homolog 2 (Drosophila) 0.907
Pten phosphatase and tensin homolog 0.904
Tgfb1 transforming growth factor, beta 1 0.903
Foxf1a forkhead box F1a 0.902
Foxg1 forkhead box G1 0.901
Cdx1 caudal type homeobox 1 0.899
Bmpr1a bone morphogenetic protein receptor, type 1A 0.897
Tbx1 T-box 1 0.895
Nog noggin 0.895
Gli2 GLI-Kruppel family member GLI2 0.894
Foxc2 forkhead box C2 0.889
Ret ret proto-oncogene 0.888
Emx2 empty spiracles homolog 2 (Drosophila) 0.886
Csf1 colony stimulating factor 1 (macrophage) 0.885
Pkd1 polycystic kidney disease 1 homolog 0.884
Trp63 transformation related protein 63 0.883
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.874
Hand2 heart and neural crest derivatives expressed transcript 2 0.873
Smad1 MAD homolog 1 (Drosophila) 0.867
Ptk7 PTK7 protein tyrosine kinase 7 0.865
Onecut1 one cut domain, family member 1 0.864
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.859
Plcg1 phospholipase C, gamma 1 0.859
Hoxa3 homeobox A3 0.854
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.851
Wnt3a wingless-related MMTV integration site 3A 0.844
Tbx2 T-box 2 0.835
Pbx1 pre B-cell leukemia transcription factor 1 0.835
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.835
Fgf3 fibroblast growth factor 3 0.833
Hoxd13 homeobox D13 0.832
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.830
Gas1 growth arrest specific 1 0.828
Rxra retinoid X receptor alpha 0.828
Lrp6 low density lipoprotein receptor-related protein 6 0.824
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.815
Bbs4 Bardet-Biedl syndrome 4 (human) 0.814
Hoxd11 homeobox D11 0.810
Alx4 aristaless-like homeobox 4 0.807
Dlx5 distal-less homeobox 5 0.804
Tlx3 T-cell leukemia, homeobox 3 0.799
Eya1 eyes absent 1 homolog (Drosophila) 0.794
Meox2 mesenchyme homeobox 2 0.792
Nos3 nitric oxide synthase 3, endothelial cell 0.788
Rara retinoic acid receptor, alpha 0.785
Lhx9 LIM homeobox protein 9 0.783
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
his-64 Protein HIS-64 0.992
his-45 Protein HIS-45 0.991
his-46 Protein HIS-46 0.989
his-62 Protein HIS-62 0.984
hlh-2 Protein HLH-2 0.980
egl-18 Protein EGL-18 0.980
his-48 Protein HIS-48 0.979
his-1 Protein HIS-1 0.979
elt-6 Protein ELT-6 0.971
his-30 Protein HIS-30 0.969
his-31 Protein HIS-31 0.969
his-61 Protein HIS-61 0.965
his-5 Protein HIS-5 0.963
pha-4 Protein PHA-4 0.959
his-47 Protein HIS-47 0.954
his-16 Protein HIS-16 0.953
his-68 Protein HIS-68 0.928
cam-1 Protein CAM-1 0.912
his-42 Protein HIS-42 0.906
his-29 Protein HIS-29 0.903
his-9 Protein HIS-9 0.859
his-50 Protein HIS-50 0.842
his-59 Protein HIS-59 0.809
bar-1 Protein BAR-1 0.798
fkh-2 Protein FKH-2 0.754
egl-46 Protein EGL-46 0.735
egl-27 Protein EGL-27 0.694
zip-7 Protein ZIP-7 0.663
pop-1 Protein POP-1 0.654
his-2 Protein HIS-2 0.651
his-52 Protein HIS-52 0.648
his-3 Protein HIS-3 0.620
nhr-67 Protein NHR-67 0.593
mab-5 Protein MAB-5 0.588
his-63 Protein HIS-63 0.524
mls-2 Protein MLS-2 0.491
hlh-1 Protein HLH-1 0.478
pes-1 Protein PES-1 0.469
sma-6 Protein SMA-6 0.444
his-32 Protein HIS-32 0.430
hnd-1 Protein HND-1 0.428
his-6 Protein HIS-6 0.426
mep-1 Protein MEP-1 0.419
his-14 Protein HIS-14 0.417
his-38 Protein HIS-38 0.413
lin-12 Protein LIN-12 0.386
his-4 Protein HIS-4 0.380
inx-13 Protein INX-13 0.362
vab-3 Protein VAB-3 0.360
lag-1 Protein LAG-1 0.360
tra-1 Protein TRA-1 0.355
ztf-2 Protein ZTF-2 0.348
unc-98 Protein UNC-98 0.345
lsy-2 Protein LSY-2 0.345
daf-14 Protein DAF-14 0.340
his-39 Protein HIS-39 0.331
his-15 Protein HIS-15 0.325
unc-62 Protein UNC-62 0.319
hcp-3 Protein HCP-3 0.304
flt-1 Protein FLT-1 0.303
exc-5 Protein EXC-5 0.291
xpo-1 Protein XPO-1 0.288
soc-2 Protein SOC-2 0.269
nhr-25 Protein NHR-25 0.267
vab-1 Protein VAB-1 0.265
his-43 Protein HIS-43 0.258
egl-13 Protein EGL-13 0.242
ten-1 Protein TEN-1 0.230
cnd-1 Protein CND-1 0.223
hmg-1.2 Protein HMG-1.2 0.219
rsp-1 Protein RSP-1 0.215
lin-36 Protein LIN-36 0.214
egl-15 Protein EGL-15 0.213
lin-11 Protein LIN-11 0.213
unc-42 Protein UNC-42 0.211
ceh-27 Protein CEH-27 0.199
dre-1 Protein DRE-1 0.198
bet-1 Protein BET-1 0.198
let-23 Protein LET-23 0.198
his-49 Protein HIS-49 0.196
lin-29 Protein LIN-29 0.192
R10E12.2 Protein R10E12.2 0.191
hbl-1 Protein HBL-1 0.187
sos-1 Protein SOS-1 0.185
cwn-2 Protein CWN-2 0.181
nhr-2 Protein NHR-2 0.179
CELE_F54D5.5 Protein F54D5.5 0.171
mig-5 Protein MIG-5 0.171
unc-73 Protein UNC-73 0.170
atn-1 Protein ATN-1 0.167
his-33 Protein HIS-33 0.164
lat-1 Protein LAT-1 0.164
odd-2 Protein ODD-2 0.162
mom-2 Protein MOM-2 0.158
his-7 Protein HIS-7 0.156
zfp-1 Protein ZFP-1 0.156
glp-1 Protein GLP-1 0.155
med-2 Protein MED-2 0.152
pry-1 Protein PRY-1 0.151
snr-2 Protein SNR-2 0.151
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Danio rerio
Name Description Probability Func Analog Organism
hnf1ba HNF1 homeobox Ba 1.000
bmp4 bone morphogenetic protein 4 0.997
shha sonic hedgehog a 0.997
pax2a paired box gene 2a 0.997
gli2a GLI-Kruppel family member GLI2a 0.994
ndr2 nodal-related 2 0.992
fgf3 fibroblast growth factor 3 0.989
chd chordin 0.988
smad9 MAD homolog 9 (Drosophila) 0.983
lhx1a LIM homeobox 1a 0.978
pitx2 paired-like homeodomain transcription factor 2 0.975
gdf6a growth differentiation factor 6a 0.972
bmpr1aa bone morphogenetic protein receptor, type 1aa 0.972
runx2b runt-related transcription factor 2b 0.970
lft1 lefty1 0.968
sox32 SRY-box containing gene 32 0.966
eya1 eyes absent homolog 1 0.965
tbx20 T-box 20 0.964
cdh1 cadherin 1, epithelial 0.963
acvr1b activin A receptor, type IB 0.959
myod1 myogenic differentiation 1 0.958
wnt5b wingless-type MMTV integration site family, member 5b 0.958
gata3 GATA-binding protein 3 0.958
vent ventral expressed homeobox 0.957
yrk Yes-related kinase 0.956
smo smoothened homolog (Drosophila) 0.949
hand2 heart and neural crest derivatives expressed transcript 2 0.946
lfng lunatic fringe homolog 0.945
pcdh8 protocadherin 8 0.944
tp53 tumor protein p53 0.943
satb2 SATB homeobox 2 0.943
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.939
hoxc8a homeo box C8a 0.938
cdx4 caudal type homeo box transcription factor 4 0.936
axin2 axin 2 (conductin, axil) 0.936
alcamb activated leukocyte cell adhesion molecule b 0.933
smad1 MAD homolog 1 (Drosophila) 0.932
dkk1b dickkopf 1b 0.929
foxa2 forkhead box A2 0.927
gli1 GLI-Kruppel family member 1 0.924
tal1 T-cell acute lymphocytic leukemia 1 0.922
flot2a flotillin 2a 0.917
eve1 even-skipped-like1 0.917
meis3 myeloid ecotropic viral integration site 3 0.915
snai1b snail homolog 1b (Drosophila) 0.911
hhip hedgehog interacting protein 0.911
admp anti-dorsalizing morphogenic protein 0.910
gsc goosecoid 0.906
ntla no tail a 0.904
crabp2a cellular retinoic acid binding protein 2, a 0.903
hoxb1b homeo box B1b 0.900
mib mind bomb 0.897
snai1a snail homolog 1a (Drosophila) 0.897
rarab retinoic acid receptor, alpha b 0.895
hoxb8a homeo box B8a 0.893
jag2 jagged 2 0.891
gbx2 gastrulation brain homeo box 2 0.891
hoxb6b homeo box B6b 0.885
ihha Indian hedgehog homolog a 0.884
hoxb5a homeo box B5a 0.884
id1 inhibitor of DNA binding 1 0.883
cxcl12b chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1) 0.881
pkd2 polycystic kidney disease 2 0.880
ets1a v-ets erythroblastosis virus E26 oncogene homolog 1a 0.875
gro1 groucho 1 0.875
fzd7b frizzled homolog 7b 0.874
dag1 dystroglycan 1 0.873
fn1 fibronectin 1 0.870
ift88 intraflagellar transport 88 homolog 0.869
tbx2a T-box gene 2a 0.861
gata6 GATA-binding protein 6 0.856
ptpra protein tyrosine phosphatase, receptor type, A 0.855
foxa3 forkhead box A3 0.851
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.849
kdrl kinase insert domain receptor like 0.845
lpar1 lysophosphatidic acid receptor 1 0.845
efnb2a ephrin B2a 0.841
gpr126 G protein-coupled receptor 126 0.840
hoxb3a homeo box B3a 0.836
ptger4a prostaglandin E receptor 4 (subtype EP4) a 0.834
spns2 spinster homolog 2 (Drosophila) 0.831
col27a1a collagen, type XXVII, alpha 1a 0.830
tbx2b T-box 2b 0.825
vcana versican a 0.824
ptgs1 prostaglandin-endoperoxide synthase 1 0.816
nog1 noggin 1 0.812
met met proto-oncogene (hepatocyte growth factor receptor) 0.812
tshb thyroid stimulating hormone, beta subunit 0.808
wnt11 wingless-type MMTV integration site family, member 11 0.808
hoxa2b homeo box A2b 0.806
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.798
boc brother of CDO 0.790
ptgs2a prostaglandin-endoperoxide synthase 2a 0.786
ptch1 patched 1 0.783
sox9b SRY-box containing gene 9b 0.782
isl2a islet2a 0.782
tbx16 T-box gene 16 0.781
fgfr4 fibroblast growth factor receptor 4 0.778
raraa retinoic acid receptor, alpha a 0.778
pax6b paired box gene 6b 0.777
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Egfr Epidermal growth factor receptor 1.000
shn schnurri 0.999
l(2)gl lethal (2) giant larvae 0.996
ci cubitus interruptus 0.994
zip zipper 0.993
wg wingless 0.987
rib ribbon 0.985
hkb huckebein 0.984
nmo nemo 0.981
ttv tout-velu 0.976
LanA Laminin A 0.975
slp1 sloppy paired 1 0.971
byn brachyenteron 0.970
Rho1 CG8416 gene product from transcript CG8416-RB 0.967
msn misshapen 0.963
aux auxillin 0.963
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.959
fz2 frizzled 2 0.955
fas faint sausage 0.954
Rac1 CG2248 gene product from transcript CG2248-RA 0.953
pnt pointed 0.949
ush u-shaped 0.946
tgo tango 0.942
mbc myoblast city 0.933
Hop Hsp70/Hsp90 organizing protein homolog 0.928
emc extra macrochaetae 0.927
Kr Kruppel 0.914
LanB1 CG7123 gene product from transcript CG7123-RA 0.913
Jra Jun-related antigen 0.912
phl pole hole 0.910
N Notch 0.899
bowl brother of odd with entrails limited 0.897
Akt1 CG4006 gene product from transcript CG4006-RA 0.881
pan pangolin 0.880
mew multiple edematous wings 0.878
dsh dishevelled 0.873
wb wing blister 0.866
bib big brain 0.856
dpp decapentaplegic 0.854
arm armadillo 0.852
ato atonal 0.846
LanB2 Laminin B2 0.831
if inflated 0.829
crb crumbs 0.824
bin biniou 0.816
frc fringe connection 0.815
mys myospheroid 0.804
inx2 innexin 2 0.802
SoxN SoxNeuro 0.789
cora coracle 0.766
norpA no receptor potential A 0.757
rl rolled 0.751
brk brinker 0.748
Src42A Src oncogene at 42A 0.747
raw CG12437 gene product from transcript CG12437-RB 0.720
eya eyes absent 0.715
Wnt4 Wnt oncogene analog 4 0.714
tld tolloid 0.705
scb scab 0.702
abd-A abdominal A 0.696
ed echinoid 0.693
CkIalpha Casein kinase Ialpha 0.692
hep hemipterous 0.688
Pvr PDGF- and VEGF-receptor related 0.688
fz frizzled 0.688
hbs hibris 0.686
lolal lola like 0.672
sog short gastrulation 0.668
nej nejire 0.663
knrl knirps-like 0.651
wntD wnt inhibitor of Dorsal 0.634
opa odd paired 0.634
rap retina aberrant in pattern 0.633
gbb glass bottom boat 0.632
smo smoothened 0.626
rok Rho-kinase 0.624
os outstretched 0.619
CycA Cyclin A 0.616
Gap1 GTPase-activating protein 1 0.615
fkh fork head 0.610
ftz fushi tarazu 0.599
Smox Smad on X 0.597
tin tinman 0.593
tll tailless 0.590
shg shotgun 0.588
Traf4 TNF-receptor-associated factor 4 0.579
eve even skipped 0.575
fj four-jointed 0.573
14-3-3zeta CG17870 gene product from transcript CG17870-RB 0.572
usp ultraspiracle 0.558
par-1 CG8201 gene product from transcript CG8201-RA 0.549
dally division abnormally delayed 0.539
pb proboscipedia 0.537
Syx1A Syntaxin 1A 0.536
pbl pebble 0.536
ftz-f1 ftz transcription factor 1 0.533
dib disembodied 0.531
Ras85D Ras oncogene at 85D 0.524
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.522
spo spook 0.521
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 1.000
ESR1 estrogen receptor 1 1.000
TP53 tumor protein p53 1.000
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.998
SMAD4 SMAD family member 4 0.998
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.994
APC adenomatous polyposis coli 0.993
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.990
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.985
TAL1 T-cell acute lymphocytic leukemia 1 0.978
EP300 E1A binding protein p300 0.975
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.973
COL1A1 collagen, type I, alpha 1 0.972
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.971
JAG1 jagged 1 0.962
SMAD2 SMAD family member 2 0.955
CAV1 caveolin 1, caveolae protein, 22kDa 0.953
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.948
JUN jun proto-oncogene 0.947
RB1 retinoblastoma 1 0.947
CREBBP CREB binding protein 0.938
RUNX1 runt-related transcription factor 1 0.905
SOX2 SRY (sex determining region Y)-box 2 0.894
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.893
SMAD7 SMAD family member 7 0.881
SP1 Sp1 transcription factor 0.879
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.875
FN1 fibronectin 1 0.868
FLNA filamin A, alpha 0.865
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.861
COL1A2 collagen, type I, alpha 2 0.856
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.839
SFRP1 secreted frizzled-related protein 1 0.835
CDC73 cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.831
COL6A1 collagen, type VI, alpha 1 0.827
C1QA complement component 1, q subcomponent, A chain 0.826
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.817
AR androgen receptor 0.815
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.805
PXN paxillin 0.788
BMP2 bone morphogenetic protein 2 0.777
COL2A1 collagen, type II, alpha 1 0.777
COL5A1 collagen, type V, alpha 1 0.776
ENG endoglin 0.770
CXCL2 chemokine (C-X-C motif) ligand 2 0.769
EGFR epidermal growth factor receptor 0.760
GSK3B glycogen synthase kinase 3 beta 0.759
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.755
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.752
HDAC1 histone deacetylase 1 0.748
PBX1 pre-B-cell leukemia homeobox 1 0.746
ZNF512B zinc finger protein 512B 0.746
COL3A1 collagen, type III, alpha 1 0.746
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.743
PRKCZ protein kinase C, zeta 0.730
FHL2 four and a half LIM domains 2 0.724
FGFR1 fibroblast growth factor receptor 1 0.720
KDM1A lysine (K)-specific demethylase 1A 0.715
LAMB1 laminin, beta 1 0.712
POU3F2 POU class 3 homeobox 2 0.708
POU5F1 POU class 5 homeobox 1 0.700
CCL20 chemokine (C-C motif) ligand 20 0.695
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.690
ERBB2IP erbb2 interacting protein 0.684
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.659
FOXD3 forkhead box D3 0.655
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.645
CXCL3 chemokine (C-X-C motif) ligand 3 0.638
COL4A1 collagen, type IV, alpha 1 0.627
ATXN1 ataxin 1 0.625
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.620
DDR2 discoidin domain receptor tyrosine kinase 2 0.615
COL7A1 collagen, type VII, alpha 1 0.615
MAP2K4 mitogen-activated protein kinase kinase 4 0.605
FZD1 frizzled homolog 1 (Drosophila) 0.576
ITGB4 integrin, beta 4 0.560
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.556
WWOX WW domain containing oxidoreductase 0.548
FOXF1 forkhead box F1 0.548
NOTCH3 notch 3 0.545
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.544
RBBP4 retinoblastoma binding protein 4 0.539
BMP1 bone morphogenetic protein 1 0.533
MYOD1 myogenic differentiation 1 0.525
IGF1R insulin-like growth factor 1 receptor 0.521
NKX2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.515
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.511
RXRA retinoid X receptor, alpha 0.502
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.497
INSR insulin receptor 0.496
SMAD6 SMAD family member 6 0.495
PAX3 paired box 3 0.485
MAPK7 mitogen-activated protein kinase 7 0.477
TCF4 transcription factor 4 0.477
FOXF2 forkhead box F2 0.471
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.462
THBS1 thrombospondin 1 0.458
SPTBN1 spectrin, beta, non-erythrocytic 1 0.454
COL4A6 collagen, type IV, alpha 6 0.448
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Tgfbr2 transforming growth factor, beta receptor II 0.519
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 0.476
Tcfe2a transcription factor E2a 0.409
Col1a1 collagen, type I, alpha 1 0.344
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.328
Col12a1 collagen, type XII, alpha 1 0.304
Gja5 gap junction protein, alpha 5 0.238
Acta2 smooth muscle alpha-actin 0.233
Manea mannosidase, endo-alpha 0.224
Acvr1 activin A receptor, type I 0.213
S1pr2 sphingosine-1-phosphate receptor 2 0.182
Adam17 ADAM metallopeptidase domain 17 0.179
Jak2 Janus kinase 2 0.179
Cald1 caldesmon 1 0.176
LOC246267 resection-induced TPI (rs11) 0.164
Strn striatin, calmodulin binding protein 0.151
Arnt aryl hydrocarbon receptor nuclear translocator 0.137
Jun Jun oncogene 0.133
Lox lysyl oxidase 0.127
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.122
Ednra endothelin receptor type A 0.112
Akap1 A kinase (PRKA) anchor protein 1 0.112
Met met proto-oncogene 0.108
Pld1 phospholipase D1 0.106
Cyth3 cytohesin 3 0.102
Bdkrb1 bradykinin receptor B1 0.100
Agtr2 angiotensin II receptor, type 2 0.098
Tcf4 transcription factor 4 0.097
Il1r1 interleukin 1 receptor, type I 0.096
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit 0.090
Id1 inhibitor of DNA binding 1 0.090
Aspg asparaginase homolog (S. cerevisiae) 0.089
Fgfr1 Fibroblast growth factor receptor 1 0.089
Irs1 insulin receptor substrate 1 0.089
Igfbp5 insulin-like growth factor binding protein 5 0.088
Cmklr1 chemokine-like receptor 1 0.085
Lamc1 laminin, gamma 1 0.085
Entpd1 ectonucleoside triphosphate diphosphohydrolase 1 0.084
Casp7 caspase 7 0.083
Agtr1a angiotensin II receptor, type 1a 0.080
Psen1 presenilin 1 0.080
Hes3 hairy and enhancer of split 3 (Drosophila) 0.079
Foxa3 forkhead box A3 0.079
Lyn v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.078
Rxra retinoid X receptor alpha 0.078
Krt14 keratin 14 0.078
Unc5b unc-5 homolog B (C. elegans) 0.077
Ceacam1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.076
Plcb2 phospholipase C, beta 2 0.076
Flna filamin A, alpha 0.076
Myo1b myosin Ib 0.075
Myh9 myosin, heavy chain 9, non-muscle 0.075
Cdk2 cyclin dependent kinase 2 0.073
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.073
Ccr1 chemokine (C-C motif) receptor 1 0.071
Mthfr methylenetetrahydrofolate reductase (NAD(P)H) 0.070
Id3 inhibitor of DNA binding 3 0.070
Sbk1 SH3-binding domain kinase 1 0.070
Gata6 GATA binding protein 6 0.070
Nr1d2 nuclear receptor subfamily 1, group D, member 2 0.070
Adar adenosine deaminase, RNA-specific 0.069
Hand2 heart and neural crest derivatives expressed 2 0.069
Ece1 endothelin converting enzyme 1 0.069
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.066
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.065
Jak1 Janus kinase 1 0.065
Ednrb endothelin receptor type B 0.065
Smad7 SMAD family member 7 0.065
Gnrhr gonadotropin releasing hormone receptor 0.063
Loxl1 lysyl oxidase-like 1 0.062
Ceacam10 carcinoembryonic antigen-related cell adhesion molecule 10 0.062
Ncr1 natural cytotoxicity triggering receptor 1 0.062
Rac1 ras-related C3 botulinum toxin substrate 1 0.061
Fgfr2 fibroblast growth factor receptor 2 0.060
Prlr prolactin receptor 0.059
Foxd3 forkhead box D3 0.058
Dab2 disabled homolog 2 (Drosophila) 0.057
Ghr growth hormone receptor 0.057
Itpr2 inositol 1,4,5-triphosphate receptor, type 2 0.057
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.057
Smad3 SMAD family member 3 0.056
Dhfr dihydrofolate reductase 0.056
Postn periostin, osteoblast specific factor 0.056
Hnf4a hepatocyte nuclear factor 4, alpha 0.055
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.054
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B 0.054
Sparc secreted protein, acidic, cysteine-rich (osteonectin) 0.054
Ets1 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) 0.054
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha 0.053
Smad1 SMAD family member 1 0.053
Col1a2 collagen, type I, alpha 2 0.053
Nab1 Ngfi-A binding protein 1 0.053
Slc13a1 solute carrier family 13 (sodium/sulfate symporters), member 1 0.053
Gip gastric inhibitory polypeptide 0.053
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.052
Myo1a myosin IA 0.051
Uox urate oxidase 0.051
Pax4 paired box 4 0.050
RT1-M5 RT1 class Ib, locus M5 0.050
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.050
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism