IMP
Process View
The network for 'negative regulation of glial cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of glial cell differentiation
Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Sox9 | SRY-box containing gene 9 | 0.999 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.998 | |
| Emx1 | empty spiracles homolog 1 (Drosophila) | 0.994 | |
| Pax3 | paired box gene 3 | 0.994 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.992 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.992 | |
| Sox2 | SRY-box containing gene 2 | 0.987 | |
| Foxc1 | forkhead box C1 | 0.981 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.974 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.971 | |
| Prrx1 | paired related homeobox 1 | 0.970 | |
| Pax6 | paired box gene 6 | 0.963 | |
| Msx1 | homeobox, msh-like 1 | 0.957 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.954 | |
| Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.938 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.929 | |
| Dlx5 | distal-less homeobox 5 | 0.927 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.913 | |
| Bmp4 | bone morphogenetic protein 4 | 0.910 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.896 | |
| Psen1 | presenilin 1 | 0.882 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.878 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.875 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.867 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.861 | |
| Smo | smoothened homolog (Drosophila) | 0.854 | |
| Fgf8 | fibroblast growth factor 8 | 0.853 | |
| Foxg1 | forkhead box G1 | 0.845 | |
| Ptch1 | patched homolog 1 | 0.835 | |
| Tbx1 | T-box 1 | 0.807 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.746 | |
| Gsc | goosecoid homeobox | 0.745 | |
| Foxc2 | forkhead box C2 | 0.744 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.736 | |
| Trp53 | transformation related protein 53 | 0.689 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.659 | |
| Dlx6 | distal-less homeobox 6 | 0.646 | |
| Cdkn1b | cyclin-dependent kinase inhibitor 1B | 0.644 | |
| Rb1 | retinoblastoma 1 | 0.636 | |
| Rxra | retinoid X receptor alpha | 0.585 | |
| Nkx2-2 | NK2 transcription factor related, locus 2 (Drosophila) | 0.577 | |
| Acvr1 | activin A receptor, type 1 | 0.575 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.571 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.564 | |
| Meox2 | mesenchyme homeobox 2 | 0.553 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.549 | |
| Pten | phosphatase and tensin homolog | 0.528 | |
| Dcx | doublecortin | 0.524 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.516 | |
| Ret | ret proto-oncogene | 0.454 | |
| Efnb2 | ephrin B2 | 0.446 | |
| Dll1 | delta-like 1 (Drosophila) | 0.415 | |
| Rarg | retinoic acid receptor, gamma | 0.395 | |
| Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.393 | |
| Rara | retinoic acid receptor, alpha | 0.390 | |
| Dlx2 | distal-less homeobox 2 | 0.383 | |
| Nog | noggin | 0.381 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.356 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.317 | |
| Rarb | retinoic acid receptor, beta | 0.307 | |
| Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.284 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.282 | |
| Chrd | chordin | 0.273 | |
| Prrx2 | paired related homeobox 2 | 0.272 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.265 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.258 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.235 | |
| Msx2 | homeobox, msh-like 2 | 0.234 | |
| Bdnf | brain derived neurotrophic factor | 0.232 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.214 | |
| Sox11 | SRY-box containing gene 11 | 0.210 | |
| Bmp7 | bone morphogenetic protein 7 | 0.201 | |
| Reln | reelin | 0.188 | |
| Hoxa2 | homeobox A2 | 0.187 | |
| Jag1 | jagged 1 | 0.185 | |
| Pdx1 | pancreatic and duodenal homeobox 1 | 0.184 | |
| Lhx5 | LIM homeobox protein 5 | 0.179 | |
| Chrnb2 | cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) | 0.173 | |
| Pax2 | paired box gene 2 | 0.165 | |
| Sall3 | sal-like 3 (Drosophila) | 0.152 | |
| Olig2 | oligodendrocyte transcription factor 2 | 0.150 | |
| Ptf1a | pancreas specific transcription factor, 1a | 0.147 | |
| Dlx1 | distal-less homeobox 1 | 0.147 | |
| Insm1 | insulinoma-associated 1 | 0.145 | |
| Hoxa1 | homeobox A1 | 0.140 | |
| Sox4 | SRY-box containing gene 4 | 0.140 | |
| Pax9 | paired box gene 9 | 0.138 | |
| Nf1 | neurofibromatosis 1 | 0.135 | |
| Cckbr | cholecystokinin B receptor | 0.132 | |
| Foxi3 | forkhead box I3 | 0.124 | |
| Trp63 | transformation related protein 63 | 0.123 | |
| Hmx1 | H6 homeobox 1 | 0.121 | |
| Sox10 | SRY-box containing gene 10 | 0.117 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.113 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.110 | |
| Lhx3 | LIM homeobox protein 3 | 0.110 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.103 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.101 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.614 | |
| JAG1 | jagged 1 | 0.606 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.561 | |
| APC | adenomatous polyposis coli | 0.319 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.286 | |
| HDAC6 | histone deacetylase 6 | 0.277 | |
| NOTCH3 | notch 3 | 0.275 | |
| ALB | albumin | 0.250 | |
| BTRC | beta-transducin repeat containing | 0.242 | |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.235 | |
| CDC14B | CDC14 cell division cycle 14 homolog B (S. cerevisiae) | 0.213 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.176 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.129 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.122 | |
| PSEN1 | presenilin 1 | 0.110 | |
| GLIS2 | GLIS family zinc finger 2 | 0.107 | |
| TCF4 | transcription factor 4 | 0.104 | |
| BMP7 | bone morphogenetic protein 7 | 0.089 | |
| FBXW7 | F-box and WD repeat domain containing 7 | 0.086 | |
| FERMT2 | fermitin family member 2 | 0.081 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.080 | |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.071 | |
| FBXW11 | F-box and WD repeat domain containing 11 | 0.069 | |
| AXIN1 | axin 1 | 0.069 | |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.066 | |
| SMAD7 | SMAD family member 7 | 0.064 | |
| JUP | junction plakoglobin | 0.056 | |
| HIST1H3B | histone cluster 1, H3b | 0.055 | |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.055 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.052 | |
| BMP2 | bone morphogenetic protein 2 | 0.050 | |
| APP | amyloid beta (A4) precursor protein | 0.049 | |
| YAP1 | Yes-associated protein 1 | 0.042 | |
| XIAP | X-linked inhibitor of apoptosis | 0.041 | |
| MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.032 | |
| SKP1 | S-phase kinase-associated protein 1 | 0.032 | |
| KRT8 | keratin 8 | 0.032 | |
| MAX | MYC associated factor X | 0.032 | |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.031 | |
| EMD | emerin | 0.029 | |
| FGA | fibrinogen alpha chain | 0.028 | |
| NOTCH2 | notch 2 | 0.027 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.027 | |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.026 | |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.026 | |
| DLL1 | delta-like 1 (Drosophila) | 0.026 | |
| HIST1H4F | histone cluster 1, H4f | 0.026 | |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.025 | |
| ZNF331 | zinc finger protein 331 | 0.025 | |
| JAG2 | jagged 2 | 0.024 | |
| SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.024 | |
| PKP4 | plakophilin 4 | 0.023 | |
| MYOD1 | myogenic differentiation 1 | 0.023 | |
| BBS10 | Bardet-Biedl syndrome 10 | 0.022 | |
| CSNK1E | casein kinase 1, epsilon | 0.021 | |
| ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.021 | |
| REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.019 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.019 | |
| KAT2B | K(lysine) acetyltransferase 2B | 0.019 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.019 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.018 | |
| CUL1 | cullin 1 | 0.018 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.018 | |
| OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.018 | |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.018 | |
| SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.017 | |
| PLG | plasminogen | 0.017 | |
| CTNNBIP1 | catenin, beta interacting protein 1 | 0.017 | |
| EZR | ezrin | 0.017 | |
| DLL3 | delta-like 3 (Drosophila) | 0.016 | |
| SMAD1 | SMAD family member 1 | 0.016 | |
| SLC38A3 | solute carrier family 38, member 3 | 0.016 | |
| GHR | growth hormone receptor | 0.016 | |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.016 | |
| STRN3 | striatin, calmodulin binding protein 3 | 0.015 | |
| NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.015 | |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.015 | |
| SMAD4 | SMAD family member 4 | 0.015 | |
| PTK7 | PTK7 protein tyrosine kinase 7 | 0.015 | |
| PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.015 | |
| CAMKV | CaM kinase-like vesicle-associated | 0.014 | |
| ASCL1 | achaete-scute complex homolog 1 (Drosophila) | 0.014 | |
| CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.014 | |
| SYN2 | synapsin II | 0.014 | |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.014 | |
| WEE1 | WEE1 homolog (S. pombe) | 0.014 | |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 | 0.014 | |
| SMAD6 | SMAD family member 6 | 0.013 | |
| GFI1B | growth factor independent 1B transcription repressor | 0.013 | |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.013 | |
| MSX1 | msh homeobox 1 | 0.013 | |
| LRP2 | low density lipoprotein receptor-related protein 2 | 0.013 | |
| SPECC1L | sperm antigen with calponin homology and coiled-coil domains 1-like | 0.013 | |
| KRT18 | keratin 18 | 0.013 | |
| MAK | male germ cell-associated kinase | 0.013 | |
| HMGCL | 3-hydroxymethyl-3-methylglutaryl-CoA lyase | 0.013 | |
| EGR1 | early growth response 1 | 0.013 | |
| CDC34 | cell division cycle 34 homolog (S. cerevisiae) | 0.013 | |
| PXN | paxillin | 0.013 | |
| SOX2 | SRY (sex determining region Y)-box 2 | 0.013 |