The network for 'regulation of polysaccharide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of polysaccharide metabolic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.

Mus musculus
Name Description Probability Func Analog Organism
Grb10 growth factor receptor bound protein 10 0.983
Igf1r insulin-like growth factor I receptor 0.931
Insr insulin receptor 0.918
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.902
Nos3 nitric oxide synthase 3, endothelial cell 0.693
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.621
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.601
Ins2 insulin II 0.452
Lepr leptin receptor 0.420
Igf2 insulin-like growth factor 2 0.310
Socs1 suppressor of cytokine signaling 1 0.308
Pim1 proviral integration site 1 0.286
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.252
Igf2r insulin-like growth factor 2 receptor 0.245
Kl klotho 0.140
Csf1 colony stimulating factor 1 (macrophage) 0.118
Nos1 nitric oxide synthase 1, neuronal 0.104
Ptma prothymosin alpha 0.101
Irs2 insulin receptor substrate 2 0.098
Ghr growth hormone receptor 0.096
Drd2 dopamine receptor D2 0.095
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.092
Rhbdf1 rhomboid family 1 (Drosophila) 0.089
Akt1 thymoma viral proto-oncogene 1 0.082
Pparg peroxisome proliferator activated receptor gamma 0.074
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.071
Skp1a S-phase kinase-associated protein 1A 0.070
Vdr vitamin D receptor 0.062
Lep leptin 0.060
Rad21 RAD21 homolog (S. pombe) 0.057
Ins1 insulin I 0.056
Tgfa transforming growth factor alpha 0.054
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.052
Pim3 proviral integration site 3 0.051
Kcnk4 potassium channel, subfamily K, member 4 0.048
Esr1 estrogen receptor 1 (alpha) 0.047
Rplp0 ribosomal protein, large, P0 0.045
Pcdh12 protocadherin 12 0.045
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.044
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.037
Adra2a adrenergic receptor, alpha 2a 0.031
Mrc2 mannose receptor, C type 2 0.030
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.030
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.029
Cckbr cholecystokinin B receptor 0.028
Irs1 insulin receptor substrate 1 0.028
Ar androgen receptor 0.027
Hmgb1 high mobility group box 1 0.026
Tgfb1 transforming growth factor, beta 1 0.025
Cdkn1c cyclin-dependent kinase inhibitor 1C (P57) 0.025
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.025
Mfap4 microfibrillar-associated protein 4 0.025
Agtr1a angiotensin II receptor, type 1a 0.023
Mc5r melanocortin 5 receptor 0.023
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.023
Bcl3 B-cell leukemia/lymphoma 3 0.022
Tff1 trefoil factor 1 0.022
Npy2r neuropeptide Y receptor Y2 0.021
Nr0b2 nuclear receptor subfamily 0, group B, member 2 0.021
Prlr prolactin receptor 0.021
Pim2 proviral integration site 2 0.021
Nr1h4 nuclear receptor subfamily 1, group H, member 4 0.020
Sp3 trans-acting transcription factor 3 0.020
Pdx1 pancreatic and duodenal homeobox 1 0.020
Esr2 estrogen receptor 2 (beta) 0.020
Smad3 MAD homolog 3 (Drosophila) 0.020
Galr3 galanin receptor 3 0.019
a nonagouti 0.018
Hrh1 histamine receptor H1 0.018
Col1a1 collagen, type I, alpha 1 0.018
Sim1 single-minded homolog 1 (Drosophila) 0.018
Agrp agouti related protein 0.018
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.018
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.018
Nr1i3 nuclear receptor subfamily 1, group I, member 3 0.017
Pthlh parathyroid hormone-like peptide 0.017
Oxt oxytocin 0.016
Gpr27 G protein-coupled receptor 27 0.016
Inhbc inhibin beta-C 0.015
C1d C1D nuclear receptor co-repressor 0.015
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.015
Npy1r neuropeptide Y receptor Y1 0.015
Ghrh growth hormone releasing hormone 0.015
Mapkapk2 MAP kinase-activated protein kinase 2 0.015
Foxn1 forkhead box N1 0.014
Scoc short coiled-coil protein 0.014
Rtn4r reticulon 4 receptor 0.014
Trfr2 transferrin receptor 2 0.013
Gckr glucokinase regulatory protein 0.013
Adm adrenomedullin 0.013
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.013
Apln apelin 0.013
Slc12a1 solute carrier family 12, member 1 0.013
Proc protein C 0.013
Lipe lipase, hormone sensitive 0.013
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.013
Gcgr glucagon receptor 0.013
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 0.013
Pnpla2 patatin-like phospholipase domain containing 2 0.013
Rit2 Ras-like without CAAX 2 0.013
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.987
INSR insulin receptor 0.926
NUMB numb homolog (Drosophila) 0.701
GRB10 growth factor receptor-bound protein 10 0.655
IGF1R insulin-like growth factor 1 receptor 0.572
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.550
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.404
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.323
IRS1 insulin receptor substrate 1 0.309
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.308
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.305
BCL3 B-cell CLL/lymphoma 3 0.254
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.219
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.185
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.159
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.156
HIP1 huntingtin interacting protein 1 0.151
HIPK2 homeodomain interacting protein kinase 2 0.123
NOXA1 NADPH oxidase activator 1 0.123
IRS2 insulin receptor substrate 2 0.121
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.103
SH2B1 SH2B adaptor protein 1 0.090
VEGFA vascular endothelial growth factor A 0.084
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta 0.074
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2 0.074
RAB6A RAB6A, member RAS oncogene family 0.069
PARD6A par-6 partitioning defective 6 homolog alpha (C. elegans) 0.068
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.066
APP amyloid beta (A4) precursor protein 0.064
NRP1 neuropilin 1 0.062
LZTS2 leucine zipper, putative tumor suppressor 2 0.062
ENG endoglin 0.057
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.054
ITGB1BP3 integrin beta 1 binding protein 3 0.054
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.052
SH3RF1 SH3 domain containing ring finger 1 0.051
PRKCZ protein kinase C, zeta 0.048
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.043
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.042
STAT5B signal transducer and activator of transcription 5B 0.039
GSK3B glycogen synthase kinase 3 beta 0.033
PGF placental growth factor 0.032
PARD6B par-6 partitioning defective 6 homolog beta (C. elegans) 0.031
HR hairless homolog (mouse) 0.030
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.029
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.029
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.025
MAP3K14 mitogen-activated protein kinase kinase kinase 14 0.024
TOM1L1 target of myb1 (chicken)-like 1 0.024
NCF1 neutrophil cytosolic factor 1 0.024
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.024
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.023
DCAF7 DDB1 and CUL4 associated factor 7 0.023
PRKCA protein kinase C, alpha 0.023
CLTC clathrin, heavy chain (Hc) 0.023
LRRK2 leucine-rich repeat kinase 2 0.023
RPTOR regulatory associated protein of MTOR, complex 1 0.021
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 0.020
PICK1 protein interacting with PRKCA 1 0.020
PARD3 par-3 partitioning defective 3 homolog (C. elegans) 0.020
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.019
CAPRIN2 caprin family member 2 0.019
COL6A1 collagen, type VI, alpha 1 0.018
CCND1 cyclin D1 0.018
PARD6G par-6 partitioning defective 6 homolog gamma (C. elegans) 0.017
CXXC5 CXXC finger protein 5 0.017
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) 0.017
HNF4A hepatocyte nuclear factor 4, alpha 0.017
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.016
OSBP oxysterol binding protein 0.016
THBS1 thrombospondin 1 0.016
STC1 stanniocalcin 1 0.016
PRKCB protein kinase C, beta 0.016
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 0.015
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.015
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B 0.015
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.014
CREB1 cAMP responsive element binding protein 1 0.014
LCK lymphocyte-specific protein tyrosine kinase 0.014
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.014
PDGFC platelet derived growth factor C 0.014
CDCP1 CUB domain containing protein 1 0.013
PPP1R3F protein phosphatase 1, regulatory (inhibitor) subunit 3F 0.012
EGFR epidermal growth factor receptor 0.012
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2 0.012
GCKR glucokinase (hexokinase 4) regulator 0.012
LDLR low density lipoprotein receptor 0.012
HTT huntingtin 0.012
MBL2 mannose-binding lectin (protein C) 2, soluble 0.011
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.011
RICTOR RPTOR independent companion of MTOR, complex 2 0.011
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.011
PILRA paired immunoglobin-like type 2 receptor alpha 0.011
OCRL oculocerebrorenal syndrome of Lowe 0.010
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.010
FAM117B family with sequence similarity 117, member B 0.010
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.010
LLGL1 lethal giant larvae homolog 1 (Drosophila) 0.010
COL2A1 collagen, type II, alpha 1 0.010
EPAS1 endothelial PAS domain protein 1 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GLC7 Glc7p 0.508
GSY2 Gsy2p 0.358
RHO1 Rho1p 0.257
FLO8 Flo8p 0.190
RDI1 Rdi1p 0.162
MSS11 Mss11p 0.158
MMR1 Mmr1p 0.156
GLG2 Glg2p 0.151
EXO70 Exo70p 0.136
SFL1 Sfl1p 0.116
GIP2 Gip2p 0.105
UGP1 Ugp1p 0.098
HXK1 Hxk1p 0.080
BEM4 Bem4p 0.080
GPH1 Gph1p 0.074
PIG2 Pig2p 0.062
GDB1 Gdb1p 0.051
HKR1 Hkr1p 0.050
HOC1 Hoc1p 0.045
GLG1 Glg1p 0.044
PCL9 Pcl9p 0.043
ROM2 Rom2p 0.041
PCL2 Pcl2p 0.041
TEC1 Tec1p 0.039
BEM2 Bem2p 0.038
PKC1 Pkc1p 0.035
PHO81 Pho81p 0.034
FYV8 Fyv8p 0.034
PCL1 Pcl1p 0.032
MBR1 Mbr1p 0.032
PHO85 Pho85p 0.031
GSY1 Gsy1p 0.028
MKK2 Mkk2p 0.026
FAR1 Far1p 0.025
CMK1 Cmk1p 0.025
GIC2 Gic2p 0.024
BEM3 Bem3p 0.024
AVT7 Avt7p 0.024
BBC1 Bbc1p 0.024
SLG1 Slg1p 0.023
SOL1 Sol1p 0.022
SAK1 Sak1p 0.022
TSL1 Tsl1p 0.022
CAK1 Cak1p 0.022
GLO3 Glo3p 0.021
YHB1 Yhb1p 0.021
YJR115W hypothetical protein 0.021
YJL181W hypothetical protein 0.021
YJL107C hypothetical protein 0.021
MER1 Mer1p 0.020
MRK1 Mrk1p 0.020
YNL144C hypothetical protein 0.020
YPL014W hypothetical protein 0.020
PCL5 Pcl5p 0.020
CDC24 Cdc24p 0.020
OSH3 Osh3p 0.019
YNR014W hypothetical protein 0.019
THG1 Thg1p 0.019
RMD5 Rmd5p 0.019
SRD1 Srd1p 0.018
NDD1 Ndd1p 0.018
YMR210W hypothetical protein 0.018
LEU2 Leu2p 0.018
BPH1 Bph1p 0.017
CLB1 Clb1p 0.017
YIL151C hypothetical protein 0.017
SOL2 Sol2p 0.017
APM2 Apm2p 0.017
PSK1 Psk1p 0.017
HOR7 Hor7p 0.017
MSN1 Msn1p 0.017
PRS2 Prs2p 0.016
YLR455W hypothetical protein 0.016
YOL038C-A hypothetical protein 0.016
YCK3 Yck3p 0.016
DCS2 Dcs2p 0.016
KIN28 Kin28p 0.016
YLR162W hypothetical protein 0.016
MAL32 Mal32p 0.016
NEM1 Nem1p 0.015
PAH1 Pah1p 0.015
CPD1 Cpd1p 0.015
YLR177W hypothetical protein 0.015
BDH1 Bdh1p 0.015
YKR075C hypothetical protein 0.015
FSH1 Fsh1p 0.015
ICY1 Icy1p 0.015
MBF1 Mbf1p 0.015
CHA4 Cha4p 0.015
GBP2 Gbp2p 0.015
CDC42 Cdc42p 0.015
YLR264C-A hypothetical protein 0.015
ITR2 Itr2p 0.015
HSV2 Hsv2p 0.015
ENT1 Ent1p 0.014
SGN1 Sgn1p 0.014
VHS1 Vhs1p 0.014
URA3 Ura3p 0.014
YIR035C hypothetical protein 0.014
YHR009C hypothetical protein 0.014