IMP
Process View
The network for 'negative regulation of glomerular mesangial cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of glomerular mesangial cell proliferation
Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 0.997 | |
| Shh | sonic hedgehog | 0.995 | |
| Foxc1 | forkhead box C1 | 0.972 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.972 | |
| Bmp4 | bone morphogenetic protein 4 | 0.940 | |
| Sox9 | SRY-box containing gene 9 | 0.893 | |
| Foxc2 | forkhead box C2 | 0.845 | |
| Msx1 | homeobox, msh-like 1 | 0.842 | |
| Smo | smoothened homolog (Drosophila) | 0.799 | |
| Prrx1 | paired related homeobox 1 | 0.795 | |
| Tbx1 | T-box 1 | 0.718 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.699 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.684 | |
| Bmp7 | bone morphogenetic protein 7 | 0.648 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.579 | |
| Dlx5 | distal-less homeobox 5 | 0.559 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.529 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.500 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.498 | |
| Fgf8 | fibroblast growth factor 8 | 0.431 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.422 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.417 | |
| Rarb | retinoic acid receptor, beta | 0.401 | |
| Pax2 | paired box gene 2 | 0.390 | |
| Chrd | chordin | 0.353 | |
| Vegfa | vascular endothelial growth factor A | 0.339 | |
| Pax3 | paired box gene 3 | 0.337 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.299 | |
| Prrx2 | paired related homeobox 2 | 0.283 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.269 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.259 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.240 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.185 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.170 | |
| Rarg | retinoic acid receptor, gamma | 0.167 | |
| Ednra | endothelin receptor type A | 0.162 | |
| Nr4a1 | nuclear receptor subfamily 4, group A, member 1 | 0.144 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.143 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.140 | |
| Ptch1 | patched homolog 1 | 0.133 | |
| Bmp2 | bone morphogenetic protein 2 | 0.125 | |
| Hoxa1 | homeobox A1 | 0.097 | |
| Rara | retinoic acid receptor, alpha | 0.089 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.084 | |
| Foxg1 | forkhead box G1 | 0.079 | |
| Bmper | BMP-binding endothelial regulator | 0.064 | |
| Runx2 | runt related transcription factor 2 | 0.061 | |
| Nab2 | Ngfi-A binding protein 2 | 0.061 | |
| Rxra | retinoid X receptor alpha | 0.061 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.058 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.058 | |
| Apc | adenomatosis polyposis coli | 0.057 | |
| Jag1 | jagged 1 | 0.056 | |
| Fos | FBJ osteosarcoma oncogene | 0.056 | |
| Lhx1 | LIM homeobox protein 1 | 0.055 | |
| Ptgs2 | prostaglandin-endoperoxide synthase 2 | 0.055 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.052 | |
| Alx1 | ALX homeobox 1 | 0.051 | |
| Vhl | von Hippel-Lindau tumor suppressor | 0.051 | |
| Msx2 | homeobox, msh-like 2 | 0.049 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.047 | |
| Gsc | goosecoid homeobox | 0.045 | |
| Ece1 | endothelin converting enzyme 1 | 0.043 | |
| Efnb2 | ephrin B2 | 0.040 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.036 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.033 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.033 | |
| Bcl2 | B-cell leukemia/lymphoma 2 | 0.029 | |
| Gja1 | gap junction protein, alpha 1 | 0.027 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.026 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.025 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.025 | |
| Nog | noggin | 0.025 | |
| Acvr1 | activin A receptor, type 1 | 0.024 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.023 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.022 | |
| Pten | phosphatase and tensin homolog | 0.021 | |
| Itga3 | integrin alpha 3 | 0.021 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.020 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.020 | |
| Tcf21 | transcription factor 21 | 0.018 | |
| En1 | engrailed 1 | 0.017 | |
| Mn1 | meningioma 1 | 0.017 | |
| Junb | Jun-B oncogene | 0.016 | |
| Hoxa2 | homeobox A2 | 0.016 | |
| Egr2 | early growth response 2 | 0.015 | |
| Sox4 | SRY-box containing gene 4 | 0.015 | |
| Dusp1 | dual specificity phosphatase 1 | 0.014 | |
| Pax6 | paired box gene 6 | 0.014 | |
| Crim1 | cysteine rich transmembrane BMP regulator 1 (chordin like) | 0.014 | |
| Sox11 | SRY-box containing gene 11 | 0.014 | |
| Dlx2 | distal-less homeobox 2 | 0.014 | |
| Ret | ret proto-oncogene | 0.013 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.013 | |
| Erbb2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.013 | |
| Gas1 | growth arrest specific 1 | 0.012 | |
| Jun | Jun oncogene | 0.012 | |
| Gata4 | GATA binding protein 4 | 0.012 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.011 | |
| Fgf10 | fibroblast growth factor 10 | 0.011 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| BMPR1A | bone morphogenetic protein receptor, type IA | 1.000 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.983 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.956 | |
| FSTL1 | follistatin-like 1 | 0.763 | |
| NOG | noggin | 0.680 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.472 | |
| DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.458 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.329 | |
| ZFYVE9 | zinc finger, FYVE domain containing 9 | 0.252 | |
| BMP4 | bone morphogenetic protein 4 | 0.229 | |
| BMP2 | bone morphogenetic protein 2 | 0.120 | |
| TAOK1 | TAO kinase 1 | 0.053 | |
| COL2A1 | collagen, type II, alpha 1 | 0.042 | |
| ZNF205 | zinc finger protein 205 | 0.035 | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.031 | |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.029 | |
| BMP8B | bone morphogenetic protein 8b | 0.029 | |
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.028 | |
| FGF4 | fibroblast growth factor 4 | 0.024 | |
| BMP3 | bone morphogenetic protein 3 | 0.023 | |
| EFNB3 | ephrin-B3 | 0.017 | |
| ZNF512B | zinc finger protein 512B | 0.017 | |
| ST8SIA2 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 | 0.015 | |
| C8orf33 | chromosome 8 open reading frame 33 | 0.014 | |
| FOXF2 | forkhead box F2 | 0.013 | |
| PITX2 | paired-like homeodomain 2 | 0.012 | |
| HAND1 | heart and neural crest derivatives expressed 1 | 0.012 | |
| FOXF1 | forkhead box F1 | 0.012 | |
| MYOC | myocilin, trabecular meshwork inducible glucocorticoid response | 0.012 | |
| TGFB2 | transforming growth factor, beta 2 | 0.012 | |
| CEP164 | centrosomal protein 164kDa | 0.012 | |
| PRDM14 | PR domain containing 14 | 0.012 | |
| BMP6 | bone morphogenetic protein 6 | 0.011 | |
| WNT11 | wingless-type MMTV integration site family, member 11 | 0.011 | |
| GDF5 | growth differentiation factor 5 | 0.011 | |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 | 0.010 | |
| TG | thyroglobulin | 0.010 | |
| DLX4 | distal-less homeobox 4 | 0.010 |