IMP
Process View
The network for 'canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
canonical wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation
The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Shh | sonic hedgehog | 0.997 | |
| Bmp4 | bone morphogenetic protein 4 | 0.996 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.994 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.972 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.971 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.953 | |
| Apc | adenomatosis polyposis coli | 0.945 | |
| Foxc1 | forkhead box C1 | 0.941 | |
| Pten | phosphatase and tensin homolog | 0.892 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.828 | |
| Smo | smoothened homolog (Drosophila) | 0.814 | |
| Psen1 | presenilin 1 | 0.759 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.724 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.708 | |
| Foxc2 | forkhead box C2 | 0.676 | |
| Pax3 | paired box gene 3 | 0.641 | |
| Axin1 | axin 1 | 0.574 | |
| Sox9 | SRY-box containing gene 9 | 0.552 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.469 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.401 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.366 | |
| Bmp7 | bone morphogenetic protein 7 | 0.359 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.335 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.330 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.329 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.321 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.318 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.309 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.304 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.303 | |
| Vegfa | vascular endothelial growth factor A | 0.286 | |
| Tbx3 | T-box 3 | 0.282 | |
| Foxg1 | forkhead box G1 | 0.245 | |
| Fgf8 | fibroblast growth factor 8 | 0.244 | |
| Apoe | apolipoprotein E | 0.243 | |
| Rarg | retinoic acid receptor, gamma | 0.241 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.200 | |
| Jag1 | jagged 1 | 0.199 | |
| Rara | retinoic acid receptor, alpha | 0.193 | |
| Rxra | retinoid X receptor alpha | 0.188 | |
| Msx1 | homeobox, msh-like 1 | 0.188 | |
| Rb1 | retinoblastoma 1 | 0.174 | |
| Efnb2 | ephrin B2 | 0.173 | |
| Trp53 | transformation related protein 53 | 0.165 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.163 | |
| Prrx1 | paired related homeobox 1 | 0.161 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.159 | |
| Rarb | retinoic acid receptor, beta | 0.156 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.146 | |
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.144 | |
| Acvr1 | activin A receptor, type 1 | 0.140 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.138 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.128 | |
| Tbx1 | T-box 1 | 0.128 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.128 | |
| Meox2 | mesenchyme homeobox 2 | 0.122 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.119 | |
| Egfr | epidermal growth factor receptor | 0.104 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.103 | |
| Ptch1 | patched homolog 1 | 0.097 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.097 | |
| Chrd | chordin | 0.094 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.092 | |
| Dlx5 | distal-less homeobox 5 | 0.088 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.088 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.086 | |
| Ece1 | endothelin converting enzyme 1 | 0.083 | |
| Npc1 | Niemann Pick type C1 | 0.078 | |
| Msx2 | homeobox, msh-like 2 | 0.076 | |
| Runx2 | runt related transcription factor 2 | 0.075 | |
| Itga3 | integrin alpha 3 | 0.074 | |
| Wls | wntless homolog (Drosophila) | 0.070 | |
| Htt | huntingtin | 0.070 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.069 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.068 | |
| Numb | numb gene homolog (Drosophila) | 0.066 | |
| Ctnnd1 | catenin (cadherin associated protein), delta 1 | 0.065 | |
| Col1a1 | collagen, type I, alpha 1 | 0.062 | |
| Ctnna1 | catenin (cadherin associated protein), alpha 1 | 0.062 | |
| App | amyloid beta (A4) precursor protein | 0.054 | |
| Sox2 | SRY-box containing gene 2 | 0.053 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.046 | |
| Smtn | smoothelin | 0.045 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.043 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.041 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.041 | |
| Sox11 | SRY-box containing gene 11 | 0.041 | |
| Pax2 | paired box gene 2 | 0.040 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.040 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.038 | |
| Foxa2 | forkhead box A2 | 0.036 | |
| Bmp2 | bone morphogenetic protein 2 | 0.035 | |
| Prrx2 | paired related homeobox 2 | 0.035 | |
| Mks1 | Meckel syndrome, type 1 | 0.034 | |
| Trp63 | transformation related protein 63 | 0.033 | |
| Nf1 | neurofibromatosis 1 | 0.033 | |
| Tax1bp3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.031 | |
| Pax6 | paired box gene 6 | 0.031 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.031 |
