The network for 'regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of transcription from rna polymerase ii promoter involved in definitive endodermal cell fate specification

Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 0.999
Gli3 GLI-Kruppel family member GLI3 0.999
Fgfr2 fibroblast growth factor receptor 2 0.997
Pax3 paired box gene 3 0.992
Fgf8 fibroblast growth factor 8 0.966
Isl1 ISL1 transcription factor, LIM/homeodomain 0.960
Tcfap2a transcription factor AP-2, alpha 0.935
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.919
Bmp4 bone morphogenetic protein 4 0.895
Chd7 chromodomain helicase DNA binding protein 7 0.880
Otx2 orthodenticle homolog 2 (Drosophila) 0.878
Eya1 eyes absent 1 homolog (Drosophila) 0.872
Pax6 paired box gene 6 0.832
Pitx2 paired-like homeodomain transcription factor 2 0.796
Meox2 mesenchyme homeobox 2 0.789
Msx1 homeobox, msh-like 1 0.719
Foxc1 forkhead box C1 0.718
Hand1 heart and neural crest derivatives expressed transcript 1 0.662
Prrx1 paired related homeobox 1 0.620
Tgfb2 transforming growth factor, beta 2 0.602
Fgf10 fibroblast growth factor 10 0.588
Pax2 paired box gene 2 0.536
Ednra endothelin receptor type A 0.521
Foxc2 forkhead box C2 0.448
Gli2 GLI-Kruppel family member GLI2 0.443
Hand2 heart and neural crest derivatives expressed transcript 2 0.429
She src homology 2 domain-containing transforming protein E 0.424
Smo smoothened homolog (Drosophila) 0.408
Gbx2 gastrulation brain homeobox 2 0.379
Tbx1 T-box 1 0.337
Fgfr1 fibroblast growth factor receptor 1 0.332
Nog noggin 0.323
Nf1 neurofibromatosis 1 0.314
Foxg1 forkhead box G1 0.301
Bmp7 bone morphogenetic protein 7 0.292
Fgfr3 fibroblast growth factor receptor 3 0.288
Alx4 aristaless-like homeobox 4 0.279
Dlx5 distal-less homeobox 5 0.262
Efnb2 ephrin B2 0.250
Emx1 empty spiracles homolog 1 (Drosophila) 0.241
Rarg retinoic acid receptor, gamma 0.226
Sox11 SRY-box containing gene 11 0.223
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.214
Hes1 hairy and enhancer of split 1 (Drosophila) 0.212
Gdnf glial cell line derived neurotrophic factor 0.205
Rarb retinoic acid receptor, beta 0.200
Ptch1 patched homolog 1 0.199
Col2a1 collagen, type II, alpha 1 0.187
Gata4 GATA binding protein 4 0.187
Sall4 sal-like 4 (Drosophila) 0.177
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.176
Sox2 SRY-box containing gene 2 0.167
Pou5f1 POU domain, class 5, transcription factor 1 0.159
Pitx1 paired-like homeodomain transcription factor 1 0.158
Ntf3 neurotrophin 3 0.155
Jag1 jagged 1 0.151
Fgf3 fibroblast growth factor 3 0.149
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.146
Vangl2 vang-like 2 (van gogh, Drosophila) 0.146
Zeb1 zinc finger E-box binding homeobox 1 0.131
Prrx2 paired related homeobox 2 0.128
Emx2 empty spiracles homolog 2 (Drosophila) 0.121
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.115
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.115
Hes5 hairy and enhancer of split 5 (Drosophila) 0.113
Sall3 sal-like 3 (Drosophila) 0.112
Otx1 orthodenticle homolog 1 (Drosophila) 0.100
Msx2 homeobox, msh-like 2 0.095
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.092
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.090
Alx3 aristaless-like homeobox 3 0.089
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.081
Lef1 lymphoid enhancer binding factor 1 0.080
Atoh7 atonal homolog 7 (Drosophila) 0.077
Ret ret proto-oncogene 0.076
Hoxa1 homeobox A1 0.076
Pbx1 pre B-cell leukemia transcription factor 1 0.073
Sox9 SRY-box containing gene 9 0.072
Trp63 transformation related protein 63 0.066
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.065
Lmx1b LIM homeobox transcription factor 1 beta 0.064
Rara retinoic acid receptor, alpha 0.059
Tcfap2c transcription factor AP-2, gamma 0.057
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.056
Ctnnb1 catenin (cadherin associated protein), beta 1 0.055
Dlx1 distal-less homeobox 1 0.053
Bmper BMP-binding endothelial regulator 0.053
Hoxa3 homeobox A3 0.052
Chrd chordin 0.051
Alx1 ALX homeobox 1 0.049
Hoxd13 homeobox D13 0.048
Tcf15 transcription factor 15 0.046
Gsc goosecoid homeobox 0.046
Hoxa2 homeobox A2 0.046
Ptprb protein tyrosine phosphatase, receptor type, B 0.046
Fgf4 fibroblast growth factor 4 0.045
Nanog Nanog homeobox 0.043
Tbx3 T-box 3 0.042
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.042
Sox4 SRY-box containing gene 4 0.042
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism