Process View
The network for 'positive regulation of epithelial cell proliferation involved in lung morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Shh | sonic hedgehog | 1.000 | |
Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
Sox9 | SRY-box containing gene 9 | 1.000 | |
Foxc1 | forkhead box C1 | 1.000 | |
Gli2 | GLI-Kruppel family member GLI2 | 1.000 | |
Bmp4 | bone morphogenetic protein 4 | 1.000 | |
Fgf8 | fibroblast growth factor 8 | 1.000 | |
Tbx1 | T-box 1 | 1.000 | |
Foxc2 | forkhead box C2 | 1.000 | |
Bmp7 | bone morphogenetic protein 7 | 1.000 | |
Fgfr1 | fibroblast growth factor receptor 1 | 1.000 | |
Pax3 | paired box gene 3 | 1.000 | |
Smo | smoothened homolog (Drosophila) | 0.999 | |
Prrx1 | paired related homeobox 1 | 0.999 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.999 | |
Msx1 | homeobox, msh-like 1 | 0.999 | |
Pax2 | paired box gene 2 | 0.999 | |
Rarg | retinoic acid receptor, gamma | 0.999 | |
Tgfb2 | transforming growth factor, beta 2 | 0.999 | |
Dlx5 | distal-less homeobox 5 | 0.998 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.998 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.998 | |
Rarb | retinoic acid receptor, beta | 0.998 | |
Fgf10 | fibroblast growth factor 10 | 0.997 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.997 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.996 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.995 | |
Meox2 | mesenchyme homeobox 2 | 0.994 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.994 | |
Chrd | chordin | 0.993 | |
Prrx2 | paired related homeobox 2 | 0.991 | |
Tcfap2a | transcription factor AP-2, alpha | 0.989 | |
Twist2 | twist homolog 2 (Drosophila) | 0.987 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.981 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.980 | |
Hoxa1 | homeobox A1 | 0.980 | |
Msx2 | homeobox, msh-like 2 | 0.979 | |
Rara | retinoic acid receptor, alpha | 0.974 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.972 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.971 | |
Ptch1 | patched homolog 1 | 0.969 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.964 | |
Ednra | endothelin receptor type A | 0.952 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.950 | |
Pax8 | paired box gene 8 | 0.948 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.943 | |
Rxra | retinoid X receptor alpha | 0.938 | |
Nog | noggin | 0.935 | |
Trp53 | transformation related protein 53 | 0.935 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.933 | |
Jag1 | jagged 1 | 0.919 | |
Foxn1 | forkhead box N1 | 0.907 | |
Col2a1 | collagen, type II, alpha 1 | 0.904 | |
Alx4 | aristaless-like homeobox 4 | 0.904 | |
Hoxa2 | homeobox A2 | 0.893 | |
Gata4 | GATA binding protein 4 | 0.889 | |
Hoxa3 | homeobox A3 | 0.879 | |
Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.877 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.868 | |
Gsc | goosecoid homeobox | 0.842 | |
T | brachyury | 0.827 | |
Gdnf | glial cell line derived neurotrophic factor | 0.824 | |
Vegfa | vascular endothelial growth factor A | 0.822 | |
Lrp6 | low density lipoprotein receptor-related protein 6 | 0.814 | |
Gbx2 | gastrulation brain homeobox 2 | 0.814 | |
Lhx1 | LIM homeobox protein 1 | 0.800 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.780 | |
Runx2 | runt related transcription factor 2 | 0.778 | |
Lmx1b | LIM homeobox transcription factor 1 beta | 0.769 | |
Socs1 | suppressor of cytokine signaling 1 | 0.768 | |
Pbx1 | pre B-cell leukemia transcription factor 1 | 0.750 | |
Efnb2 | ephrin B2 | 0.737 | |
Wnt4 | wingless-related MMTV integration site 4 | 0.729 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.725 | |
Hoxd11 | homeobox D11 | 0.721 | |
Tbx3 | T-box 3 | 0.714 | |
Hoxa13 | homeobox A13 | 0.709 | |
Acvr1 | activin A receptor, type 1 | 0.692 | |
Tgfbr2 | transforming growth factor, beta receptor II | 0.689 | |
Pax9 | paired box gene 9 | 0.683 | |
Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.680 | |
Bmp2 | bone morphogenetic protein 2 | 0.678 | |
Tbx15 | T-box 15 | 0.672 | |
En1 | engrailed 1 | 0.649 | |
Apc | adenomatosis polyposis coli | 0.643 | |
Gli1 | GLI-Kruppel family member GLI1 | 0.636 | |
Hoxd13 | homeobox D13 | 0.613 | |
Fgf3 | fibroblast growth factor 3 | 0.603 | |
Mesp1 | mesoderm posterior 1 | 0.602 | |
Wnt1 | wingless-related MMTV integration site 1 | 0.599 | |
Hoxa10 | homeobox A10 | 0.597 | |
Pitx1 | paired-like homeodomain transcription factor 1 | 0.587 | |
Gata6 | GATA binding protein 6 | 0.586 | |
Ihh | Indian hedgehog | 0.572 | |
Egfr | epidermal growth factor receptor | 0.572 | |
Hmx3 | H6 homeobox 3 | 0.571 | |
Pthlh | parathyroid hormone-like peptide | 0.567 | |
Ret | ret proto-oncogene | 0.556 | |
Foxb1 | forkhead box B1 | 0.515 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
FGFR2 | fibroblast growth factor receptor 2 | 1.000 | |
FGF1 | fibroblast growth factor 1 (acidic) | 1.000 | |
FGFR1 | fibroblast growth factor receptor 1 | 0.999 | |
FGF10 | fibroblast growth factor 10 | 0.997 | |
RBM39 | RNA binding motif protein 39 | 0.956 | |
SRSF6 | serine/arginine-rich splicing factor 6 | 0.913 | |
FGF7 | fibroblast growth factor 7 | 0.895 | |
SRSF4 | serine/arginine-rich splicing factor 4 | 0.813 | |
FGFR3 | fibroblast growth factor receptor 3 | 0.302 | |
RNPS1 | RNA binding protein S1, serine-rich domain | 0.246 | |
FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.213 | |
FGF2 | fibroblast growth factor 2 (basic) | 0.194 | |
OGT | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 0.190 | |
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.163 | |
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.133 | |
H3F3B | H3 histone, family 3B (H3.3B) | 0.099 | |
FRS2 | fibroblast growth factor receptor substrate 2 | 0.084 | |
PLCG1 | phospholipase C, gamma 1 | 0.072 | |
CTGF | connective tissue growth factor | 0.069 | |
MAT2A | methionine adenosyltransferase II, alpha | 0.067 | |
TOE1 | target of EGR1, member 1 (nuclear) | 0.064 | |
ARGLU1 | arginine and glutamate rich 1 | 0.051 | |
SRPK1 | SRSF protein kinase 1 | 0.047 | |
TRA2B | transformer 2 beta homolog (Drosophila) | 0.043 | |
CCNL1 | cyclin L1 | 0.032 | |
NXF1 | nuclear RNA export factor 1 | 0.028 | |
HNRNPA0 | heterogeneous nuclear ribonucleoprotein A0 | 0.024 | |
SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.024 | |
ECEL1 | endothelin converting enzyme-like 1 | 0.024 | |
NOSTRIN | nitric oxide synthase trafficker | 0.021 | |
FGF3 | fibroblast growth factor 3 | 0.020 | |
NKX6-2 | NK6 homeobox 2 | 0.019 | |
SRRM2 | serine/arginine repetitive matrix 2 | 0.019 | |
SRPK2 | SRSF protein kinase 2 | 0.019 | |
HSPG2 | heparan sulfate proteoglycan 2 | 0.018 | |
SRSF5 | serine/arginine-rich splicing factor 5 | 0.015 | |
GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 | 0.015 | |
OLFM2 | olfactomedin 2 | 0.014 | |
CNTN1 | contactin 1 | 0.013 | |
FGFBP1 | fibroblast growth factor binding protein 1 | 0.013 | |
HCN4 | hyperpolarization activated cyclic nucleotide-gated potassium channel 4 | 0.012 | |
PRPF38A | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 0.012 | |
FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.012 | |
SRSF7 | serine/arginine-rich splicing factor 7 | 0.011 | |
WNT1 | wingless-type MMTV integration site family, member 1 | 0.011 | |
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.011 | |
JMJD6 | jumonji domain containing 6 | 0.011 | |
FGF6 | fibroblast growth factor 6 | 0.011 | |
FGF19 | fibroblast growth factor 19 | 0.010 | |
AMN | amnionless homolog (mouse) | 0.010 | |
WNT3 | wingless-type MMTV integration site family, member 3 | 0.010 |