The network for 'positive regulation of epithelial cell proliferation involved in lung morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of epithelial cell proliferation involved in lung morphogenesis

Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.

Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Sox9 SRY-box containing gene 9 1.000
Foxc1 forkhead box C1 1.000
Gli2 GLI-Kruppel family member GLI2 1.000
Bmp4 bone morphogenetic protein 4 1.000
Fgf8 fibroblast growth factor 8 1.000
Tbx1 T-box 1 1.000
Foxc2 forkhead box C2 1.000
Bmp7 bone morphogenetic protein 7 1.000
Fgfr1 fibroblast growth factor receptor 1 1.000
Pax3 paired box gene 3 1.000
Smo smoothened homolog (Drosophila) 0.999
Prrx1 paired related homeobox 1 0.999
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.999
Msx1 homeobox, msh-like 1 0.999
Pax2 paired box gene 2 0.999
Rarg retinoic acid receptor, gamma 0.999
Tgfb2 transforming growth factor, beta 2 0.999
Dlx5 distal-less homeobox 5 0.998
Pitx2 paired-like homeodomain transcription factor 2 0.998
Wnt3a wingless-related MMTV integration site 3A 0.998
Rarb retinoic acid receptor, beta 0.998
Fgf10 fibroblast growth factor 10 0.997
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.997
Hand2 heart and neural crest derivatives expressed transcript 2 0.996
Ctnnb1 catenin (cadherin associated protein), beta 1 0.995
Meox2 mesenchyme homeobox 2 0.994
Fgfr3 fibroblast growth factor receptor 3 0.994
Chrd chordin 0.993
Prrx2 paired related homeobox 2 0.991
Tcfap2a transcription factor AP-2, alpha 0.989
Twist2 twist homolog 2 (Drosophila) 0.987
Eya1 eyes absent 1 homolog (Drosophila) 0.981
Hand1 heart and neural crest derivatives expressed transcript 1 0.980
Hoxa1 homeobox A1 0.980
Msx2 homeobox, msh-like 2 0.979
Rara retinoic acid receptor, alpha 0.974
Vangl2 vang-like 2 (van gogh, Drosophila) 0.972
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.971
Ptch1 patched homolog 1 0.969
Zeb1 zinc finger E-box binding homeobox 1 0.964
Ednra endothelin receptor type A 0.952
Otx2 orthodenticle homolog 2 (Drosophila) 0.950
Pax8 paired box gene 8 0.948
Emx2 empty spiracles homolog 2 (Drosophila) 0.943
Rxra retinoid X receptor alpha 0.938
Nog noggin 0.935
Trp53 transformation related protein 53 0.935
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.933
Jag1 jagged 1 0.919
Foxn1 forkhead box N1 0.907
Col2a1 collagen, type II, alpha 1 0.904
Alx4 aristaless-like homeobox 4 0.904
Hoxa2 homeobox A2 0.893
Gata4 GATA binding protein 4 0.889
Hoxa3 homeobox A3 0.879
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.877
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.868
Gsc goosecoid homeobox 0.842
T brachyury 0.827
Gdnf glial cell line derived neurotrophic factor 0.824
Vegfa vascular endothelial growth factor A 0.822
Lrp6 low density lipoprotein receptor-related protein 6 0.814
Gbx2 gastrulation brain homeobox 2 0.814
Lhx1 LIM homeobox protein 1 0.800
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.780
Runx2 runt related transcription factor 2 0.778
Lmx1b LIM homeobox transcription factor 1 beta 0.769
Socs1 suppressor of cytokine signaling 1 0.768
Pbx1 pre B-cell leukemia transcription factor 1 0.750
Efnb2 ephrin B2 0.737
Wnt4 wingless-related MMTV integration site 4 0.729
Lmx1a LIM homeobox transcription factor 1 alpha 0.725
Hoxd11 homeobox D11 0.721
Tbx3 T-box 3 0.714
Hoxa13 homeobox A13 0.709
Acvr1 activin A receptor, type 1 0.692
Tgfbr2 transforming growth factor, beta receptor II 0.689
Pax9 paired box gene 9 0.683
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.680
Bmp2 bone morphogenetic protein 2 0.678
Tbx15 T-box 15 0.672
En1 engrailed 1 0.649
Apc adenomatosis polyposis coli 0.643
Gli1 GLI-Kruppel family member GLI1 0.636
Hoxd13 homeobox D13 0.613
Fgf3 fibroblast growth factor 3 0.603
Mesp1 mesoderm posterior 1 0.602
Wnt1 wingless-related MMTV integration site 1 0.599
Hoxa10 homeobox A10 0.597
Pitx1 paired-like homeodomain transcription factor 1 0.587
Gata6 GATA binding protein 6 0.586
Ihh Indian hedgehog 0.572
Egfr epidermal growth factor receptor 0.572
Hmx3 H6 homeobox 3 0.571
Pthlh parathyroid hormone-like peptide 0.567
Ret ret proto-oncogene 0.556
Foxb1 forkhead box B1 0.515
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
FGF1 fibroblast growth factor 1 (acidic) 1.000
FGFR1 fibroblast growth factor receptor 1 0.999
FGF10 fibroblast growth factor 10 0.997
RBM39 RNA binding motif protein 39 0.956
SRSF6 serine/arginine-rich splicing factor 6 0.913
FGF7 fibroblast growth factor 7 0.895
SRSF4 serine/arginine-rich splicing factor 4 0.813
FGFR3 fibroblast growth factor receptor 3 0.302
RNPS1 RNA binding protein S1, serine-rich domain 0.246
FGF8 fibroblast growth factor 8 (androgen-induced) 0.213
FGF2 fibroblast growth factor 2 (basic) 0.194
OGT O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 0.190
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.163
NEDD4 neural precursor cell expressed, developmentally down-regulated 4 0.133
H3F3B H3 histone, family 3B (H3.3B) 0.099
FRS2 fibroblast growth factor receptor substrate 2 0.084
PLCG1 phospholipase C, gamma 1 0.072
CTGF connective tissue growth factor 0.069
MAT2A methionine adenosyltransferase II, alpha 0.067
TOE1 target of EGR1, member 1 (nuclear) 0.064
ARGLU1 arginine and glutamate rich 1 0.051
SRPK1 SRSF protein kinase 1 0.047
TRA2B transformer 2 beta homolog (Drosophila) 0.043
CCNL1 cyclin L1 0.032
NXF1 nuclear RNA export factor 1 0.028
HNRNPA0 heterogeneous nuclear ribonucleoprotein A0 0.024
SREK1 splicing regulatory glutamine/lysine-rich protein 1 0.024
ECEL1 endothelin converting enzyme-like 1 0.024
NOSTRIN nitric oxide synthase trafficker 0.021
FGF3 fibroblast growth factor 3 0.020
NKX6-2 NK6 homeobox 2 0.019
SRRM2 serine/arginine repetitive matrix 2 0.019
SRPK2 SRSF protein kinase 2 0.019
HSPG2 heparan sulfate proteoglycan 2 0.018
SRSF5 serine/arginine-rich splicing factor 5 0.015
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.015
OLFM2 olfactomedin 2 0.014
CNTN1 contactin 1 0.013
FGFBP1 fibroblast growth factor binding protein 1 0.013
HCN4 hyperpolarization activated cyclic nucleotide-gated potassium channel 4 0.012
PRPF38A PRP38 pre-mRNA processing factor 38 (yeast) domain containing A 0.012
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.012
SRSF7 serine/arginine-rich splicing factor 7 0.011
WNT1 wingless-type MMTV integration site family, member 1 0.011
EIF4A3 eukaryotic translation initiation factor 4A3 0.011
JMJD6 jumonji domain containing 6 0.011
FGF6 fibroblast growth factor 6 0.011
FGF19 fibroblast growth factor 19 0.010
AMN amnionless homolog (mouse) 0.010
WNT3 wingless-type MMTV integration site family, member 3 0.010
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism