IMP
Process View
The network for 'establishment of planar polarity involved in neural tube closure' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
establishment of planar polarity involved in neural tube closure
Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 1.000 | |
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Dvl2 | dishevelled 2, dsh homolog (Drosophila) | 1.000 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 1.000 | |
| Pax2 | paired box gene 2 | 0.999 | |
| Shh | sonic hedgehog | 0.999 | |
| Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.996 | |
| Foxc1 | forkhead box C1 | 0.994 | |
| Fgf8 | fibroblast growth factor 8 | 0.993 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.988 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.988 | |
| Sfrp2 | secreted frizzled-related protein 2 | 0.988 | |
| Bmp4 | bone morphogenetic protein 4 | 0.976 | |
| Rarg | retinoic acid receptor, gamma | 0.970 | |
| Bmp7 | bone morphogenetic protein 7 | 0.958 | |
| Fzd8 | frizzled homolog 8 (Drosophila) | 0.956 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.951 | |
| Tcfcp2l1 | transcription factor CP2-like 1 | 0.943 | |
| Sall4 | sal-like 4 (Drosophila) | 0.940 | |
| Lhx1 | LIM homeobox protein 1 | 0.939 | |
| Fgf10 | fibroblast growth factor 10 | 0.933 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.929 | |
| Vangl1 | vang-like 1 (van gogh, Drosophila) | 0.924 | |
| Fzd1 | frizzled homolog 1 (Drosophila) | 0.905 | |
| Hoxa1 | homeobox A1 | 0.903 | |
| Smo | smoothened homolog (Drosophila) | 0.901 | |
| Jag1 | jagged 1 | 0.892 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.889 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.884 | |
| Nog | noggin | 0.883 | |
| Sox2 | SRY-box containing gene 2 | 0.869 | |
| Foxc2 | forkhead box C2 | 0.843 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.809 | |
| Tbx3 | T-box 3 | 0.804 | |
| Gpc3 | glypican 3 | 0.800 | |
| Hoxa2 | homeobox A2 | 0.791 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.779 | |
| Tbx2 | T-box 2 | 0.776 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.766 | |
| Pax3 | paired box gene 3 | 0.762 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.752 | |
| Axin1 | axin 1 | 0.747 | |
| Msx1 | homeobox, msh-like 1 | 0.732 | |
| Rarb | retinoic acid receptor, beta | 0.721 | |
| Tbx1 | T-box 1 | 0.710 | |
| Dlx5 | distal-less homeobox 5 | 0.710 | |
| Foxg1 | forkhead box G1 | 0.707 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.701 | |
| Lrp2 | low density lipoprotein receptor-related protein 2 | 0.701 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.667 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.663 | |
| Otx1 | orthodenticle homolog 1 (Drosophila) | 0.660 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.655 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.654 | |
| Prrx2 | paired related homeobox 2 | 0.651 | |
| Efna2 | ephrin A2 | 0.648 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.645 | |
| Sall1 | sal-like 1 (Drosophila) | 0.643 | |
| T | brachyury | 0.642 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.613 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.609 | |
| Gopc | golgi associated PDZ and coiled-coil motif containing | 0.599 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.598 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.553 | |
| Pax8 | paired box gene 8 | 0.552 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.535 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.522 | |
| Ror1 | receptor tyrosine kinase-like orphan receptor 1 | 0.518 | |
| Dll1 | delta-like 1 (Drosophila) | 0.518 | |
| Hoxd9 | homeobox D9 | 0.511 | |
| Hoxb6 | homeobox B6 | 0.511 | |
| Ret | ret proto-oncogene | 0.504 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.494 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.484 | |
| Chrd | chordin | 0.473 | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.458 | |
| Prrx1 | paired related homeobox 1 | 0.451 | |
| Efnb2 | ephrin B2 | 0.422 | |
| Sfrp1 | secreted frizzled-related protein 1 | 0.397 | |
| Fzd7 | frizzled homolog 7 (Drosophila) | 0.397 | |
| Efna4 | ephrin A4 | 0.389 | |
| Msx2 | homeobox, msh-like 2 | 0.387 | |
| Nanog | Nanog homeobox | 0.381 | |
| Rara | retinoic acid receptor, alpha | 0.377 | |
| Sema6a | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.373 | |
| Tgfa | transforming growth factor alpha | 0.363 | |
| Fzd2 | frizzled homolog 2 (Drosophila) | 0.361 | |
| Zfp185 | zinc finger protein 185 | 0.354 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.335 | |
| Gdnf | glial cell line derived neurotrophic factor | 0.334 | |
| Gas1 | growth arrest specific 1 | 0.333 | |
| Ephb2 | Eph receptor B2 | 0.329 | |
| Ptpn14 | protein tyrosine phosphatase, non-receptor type 14 | 0.321 | |
| Sox11 | SRY-box containing gene 11 | 0.320 | |
| Sall3 | sal-like 3 (Drosophila) | 0.309 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.305 | |
| Efs | embryonal Fyn-associated substrate | 0.286 | |
| Six5 | sine oculis-related homeobox 5 homolog (Drosophila) | 0.282 | |
| En1 | engrailed 1 | 0.280 |
