IMP
Process View
The network for 'negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis
Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.995 | |
| Bmp4 | bone morphogenetic protein 4 | 0.990 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.990 | |
| Shh | sonic hedgehog | 0.978 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.961 | |
| Smo | smoothened homolog (Drosophila) | 0.894 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.847 | |
| Tbx3 | T-box 3 | 0.804 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.789 | |
| Gsk3b | glycogen synthase kinase 3 beta | 0.746 | |
| Foxc1 | forkhead box C1 | 0.741 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.726 | |
| Pkd1 | polycystic kidney disease 1 homolog | 0.701 | |
| Axin1 | axin 1 | 0.670 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.643 | |
| Apoe | apolipoprotein E | 0.570 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.557 | |
| Bmp7 | bone morphogenetic protein 7 | 0.526 | |
| Foxc2 | forkhead box C2 | 0.469 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.465 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.443 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.431 | |
| Psen1 | presenilin 1 | 0.405 | |
| Prrx1 | paired related homeobox 1 | 0.397 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.389 | |
| Sertad2 | SERTA domain containing 2 | 0.361 | |
| Msx1 | homeobox, msh-like 1 | 0.356 | |
| Npc1 | Niemann Pick type C1 | 0.353 | |
| Pax3 | paired box gene 3 | 0.323 | |
| Ptch1 | patched homolog 1 | 0.318 | |
| Meox2 | mesenchyme homeobox 2 | 0.314 | |
| Apc | adenomatosis polyposis coli | 0.307 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.298 | |
| Runx2 | runt related transcription factor 2 | 0.295 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.267 | |
| Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.251 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.230 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.219 | |
| Jag1 | jagged 1 | 0.174 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.173 | |
| Ldlr | low density lipoprotein receptor | 0.147 | |
| Sox11 | SRY-box containing gene 11 | 0.143 | |
| Fgf8 | fibroblast growth factor 8 | 0.143 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.140 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.137 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.125 | |
| Msx2 | homeobox, msh-like 2 | 0.124 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.115 | |
| Sox9 | SRY-box containing gene 9 | 0.115 | |
| Egfr | epidermal growth factor receptor | 0.108 | |
| Rarg | retinoic acid receptor, gamma | 0.107 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.104 | |
| Pick1 | protein interacting with C kinase 1 | 0.100 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.087 | |
| Rarb | retinoic acid receptor, beta | 0.087 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.086 | |
| Prrx2 | paired related homeobox 2 | 0.082 | |
| Foxg1 | forkhead box G1 | 0.082 | |
| Bmp2 | bone morphogenetic protein 2 | 0.081 | |
| Vegfa | vascular endothelial growth factor A | 0.081 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.081 | |
| Dlx5 | distal-less homeobox 5 | 0.080 | |
| Lrp5 | low density lipoprotein receptor-related protein 5 | 0.077 | |
| App | amyloid beta (A4) precursor protein | 0.076 | |
| Twsg1 | twisted gastrulation homolog 1 (Drosophila) | 0.074 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.073 | |
| Pparg | peroxisome proliferator activated receptor gamma | 0.070 | |
| Pofut1 | protein O-fucosyltransferase 1 | 0.068 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.065 | |
| Apaf1 | apoptotic peptidase activating factor 1 | 0.063 | |
| Ece1 | endothelin converting enzyme 1 | 0.062 | |
| Rara | retinoic acid receptor, alpha | 0.061 | |
| Col1a1 | collagen, type I, alpha 1 | 0.060 | |
| Mks1 | Meckel syndrome, type 1 | 0.059 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.057 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.057 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.054 | |
| Pdgfrb | platelet derived growth factor receptor, beta polypeptide | 0.053 | |
| Bmp5 | bone morphogenetic protein 5 | 0.051 | |
| Wls | wntless homolog (Drosophila) | 0.050 | |
| Phex | phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets) | 0.049 | |
| Rxra | retinoid X receptor alpha | 0.049 | |
| T | brachyury | 0.049 | |
| Itga3 | integrin alpha 3 | 0.048 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.047 | |
| Pten | phosphatase and tensin homolog | 0.046 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.045 | |
| Crtc3 | CREB regulated transcription coactivator 3 | 0.045 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.044 | |
| Lrp4 | low density lipoprotein receptor-related protein 4 | 0.041 | |
| Gas1 | growth arrest specific 1 | 0.040 | |
| Foxa2 | forkhead box A2 | 0.040 | |
| Dact1 | dapper homolog 1, antagonist of beta-catenin (xenopus) | 0.039 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.039 | |
| Acvr1 | activin A receptor, type 1 | 0.038 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.038 | |
| Tbx1 | T-box 1 | 0.038 | |
| Mesdc2 | mesoderm development candidate 2 | 0.036 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.036 |
