The network for 'protein localization to nucleus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

protein localization to nucleus

A process in which a protein is transported to, or maintained in, a location within the nucleus.

Mus musculus
Name Description Probability Func Analog Organism
Pten phosphatase and tensin homolog 1.000
Ctnnb1 catenin (cadherin associated protein), beta 1 0.999
Trp53 transformation related protein 53 0.994
Tnf tumor necrosis factor 0.990
Apc adenomatosis polyposis coli 0.989
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.976
Fgfr2 fibroblast growth factor receptor 2 0.965
Smad3 MAD homolog 3 (Drosophila) 0.939
Casp4 caspase 4, apoptosis-related cysteine peptidase 0.920
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p105 0.919
Rarg retinoic acid receptor, gamma 0.917
Fgfr1 fibroblast growth factor receptor 1 0.915
Smad4 MAD homolog 4 (Drosophila) 0.908
Pparg peroxisome proliferator activated receptor gamma 0.903
Lef1 lymphoid enhancer binding factor 1 0.897
Gli3 GLI-Kruppel family member GLI3 0.895
Col1a1 collagen, type I, alpha 1 0.895
Axin1 axin 1 0.889
Pax8 paired box gene 8 0.880
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.876
Eya1 eyes absent 1 homolog (Drosophila) 0.870
Pkd1 polycystic kidney disease 1 homolog 0.866
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.864
Fgf10 fibroblast growth factor 10 0.851
Emx1 empty spiracles homolog 1 (Drosophila) 0.841
Cbl Casitas B-lineage lymphoma 0.835
Hbb-b1 hemoglobin, beta adult major chain 0.811
Csf1 colony stimulating factor 1 (macrophage) 0.788
Shh sonic hedgehog 0.785
Ghr growth hormone receptor 0.780
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.774
Il1r1 interleukin 1 receptor, type I 0.771
Nog noggin 0.757
Rac1 RAS-related C3 botulinum substrate 1 0.756
Ptch1 patched homolog 1 0.725
Mapk14 mitogen-activated protein kinase 14 0.715
Meox2 mesenchyme homeobox 2 0.715
Smad6 MAD homolog 6 (Drosophila) 0.703
Clock circadian locomotor output cycles kaput 0.689
Cav1 caveolin 1, caveolae protein 0.687
Nf1 neurofibromatosis 1 0.686
Gli2 GLI-Kruppel family member GLI2 0.686
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.674
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.667
Apoe apolipoprotein E 0.663
Smtn smoothelin 0.649
Lta lymphotoxin A 0.648
Per2 period homolog 2 (Drosophila) 0.642
Ar androgen receptor 0.634
Msx1 homeobox, msh-like 1 0.628
Il6st interleukin 6 signal transducer 0.608
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.607
Adam17 a disintegrin and metallopeptidase domain 17 0.599
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.591
Otx2 orthodenticle homolog 2 (Drosophila) 0.588
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.587
Isl1 ISL1 transcription factor, LIM/homeodomain 0.587
Nf2 neurofibromatosis 2 0.583
Emx2 empty spiracles homolog 2 (Drosophila) 0.583
Pou3f3 POU domain, class 3, transcription factor 3 0.583
Lepr leptin receptor 0.582
Bcl2 B-cell leukemia/lymphoma 2 0.579
Vangl2 vang-like 2 (van gogh, Drosophila) 0.576
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.570
Kpnb1 karyopherin (importin) beta 1 0.570
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.563
Bmpr1a bone morphogenetic protein receptor, type 1A 0.562
Vdr vitamin D receptor 0.560
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.559
Nodal nodal 0.552
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.550
Gsk3b glycogen synthase kinase 3 beta 0.537
Casp1 caspase 1 0.535
Smad2 MAD homolog 2 (Drosophila) 0.521
Ncoa3 nuclear receptor coactivator 3 0.516
Ikzf1 IKAROS family zinc finger 1 0.514
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.511
Tbx3 T-box 3 0.511
Grb10 growth factor receptor bound protein 10 0.504
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.496
Sox17 SRY-box containing gene 17 0.487
Pnpla2 patatin-like phospholipase domain containing 2 0.484
Sox2 SRY-box containing gene 2 0.481
Lhx1 LIM homeobox protein 1 0.477
Nos2 nitric oxide synthase 2, inducible 0.476
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.475
Lyn Yamaguchi sarcoma viral (v-yes-1) oncogene homolog 0.472
Esr1 estrogen receptor 1 (alpha) 0.454
Rara retinoic acid receptor, alpha 0.450
Ptprc protein tyrosine phosphatase, receptor type, C 0.443
Thbs1 thrombospondin 1 0.441
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.441
Foxn1 forkhead box N1 0.436
Eda ectodysplasin-A 0.432
Nos3 nitric oxide synthase 3, endothelial cell 0.431
Cry2 cryptochrome 2 (photolyase-like) 0.428
Bmp4 bone morphogenetic protein 4 0.425
Tcf21 transcription factor 21 0.422
Mknk2 MAP kinase-interacting serine/threonine kinase 2 0.420
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.418
Loading network...
Caenorhabditis elegans
Name Description Probability Func Analog Organism
lmn-1 Protein LMN-1 0.209
npp-7 Protein NPP-7 0.078
lin-36 Protein LIN-36 0.049
imb-2 Protein IMB-2 0.040
sma-6 Protein SMA-6 0.038
rpn-1 Protein RPN-1 0.034
F10G8.8 Protein F10G8.8 0.032
daf-14 Protein DAF-14 0.031
ceh-20 Protein CEH-20 0.030
lag-1 Protein LAG-1 0.028
egl-18 Protein EGL-18 0.027
unc-43 Protein UNC-43 0.026
ajm-1 Protein AJM-1 0.025
cdc-48.2 Protein CDC-48.2 0.024
ttm-4 Protein TTM-4 0.024
zyg-11 Protein ZYG-11 0.022
egl-44 Protein EGL-44 0.021
daf-4 Protein DAF-4 0.021
gpb-1 Protein GPB-1 0.021
cst-1 Protein CST-1 0.021
npp-15 Protein NPP-15 0.020
pqn-59 Protein PQN-59 0.020
cin-4 Protein CIN-4 0.019
gla-3 Protein GLA-3 0.018
cst-2 Protein CST-2 0.018
cki-1 Protein CKI-1 0.017
zyg-9 Protein ZYG-9 0.017
npp-12 Protein NPP-12 0.017
lin-25 Protein LIN-25 0.017
daf-7 Protein DAF-7 0.017
ZK180.6 Protein ZK180.6 0.016
lin-45 Protein LIN-45 0.016
ain-1 Protein AIN-1 0.016
gpb-2 Protein GPB-2 0.016
D1081.8 Protein D1081.8 0.015
dsh-2 Protein DSH-2 0.015
mpk-1 Protein MPK-1 0.015
exc-5 Protein EXC-5 0.015
nmy-2 Protein NMY-2 0.015
K10D6.4 Protein K10D6.4 0.014
aha-1 Protein AHA-1 0.014
ttyh-1 Protein TTYH-1 0.014
axl-1 Protein AXL-1 0.014
hbl-1 Protein HBL-1 0.014
ttm-5 Protein TTM-5 0.013
pmk-1 Protein PMK-1 0.013
daf-21 Protein DAF-21 0.013
plc-3 Protein PLC-3 0.013
K02A6.2 Protein K02A6.2 0.013
gld-1 Protein GLD-1 0.013
T12E12.1 Protein T12E12.1 0.013
prp-8 Protein PRP-8 0.013
F59C12.3 Protein F59C12.3 0.012
daf-11 Protein DAF-11 0.012
smf-3 Protein SMF-3 0.012
ceh-16 Protein CEH-16 0.012
par-5 Protein PAR-5 0.012
plc-1 Protein PLC-1 0.012
kin-29 Protein KIN-29 0.011
itr-1 Protein ITR-1 0.011
bath-38 Protein BATH-38 0.011
sel-8 Protein SEL-8 0.010
daf-3 Protein DAF-3 0.010
nhr-64 Protein NHR-64 0.010
dhc-1 Protein DHC-1 0.010
csnk-1 Protein CSNK-1 0.010
C15C7.5 Protein C15C7.5 0.010
F55C12.5 Protein F55C12.5 0.010
zyg-8 Protein ZYG-8 0.010
unc-52 Protein UNC-52 0.010
F14B8.6 Protein F14B8.6 0.010
daf-12 Protein DAF-12 0.010
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
ptch2 patched 2 0.959
bmp2b bone morphogenetic protein 2b 0.945
bmp4 bone morphogenetic protein 4 0.906
cdh1 cadherin 1, epithelial 0.850
igf1rb insulin-like growth factor 1b receptor 0.791
fgf10a fibroblast growth factor 10a 0.762
kif17 kinesin family member 17 0.700
boc brother of CDO 0.633
mapk3 mitogen-activated protein kinase 3 0.623
osr1 odd-skipped related 1 (Drosophila) 0.615
cxcr4a chemokine (C-X-C motif) receptor 4a 0.613
cd63 Cd63 antigen 0.581
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.564
cdh2 cadherin 2, neuronal 0.545
plk1 polo-like kinase 1 (Drosophila) 0.535
tnfrsfa tumor necrosis factor receptor superfamily, member a 0.535
cmyb transcription factor cmyb 0.530
mapk12 mitogen-activated protein kinase 12 0.509
nf1a neurofibromin 1a 0.507
foxa2 forkhead box A2 0.506
traf4a tnf receptor-associated factor 4a 0.486
wnt11r wingless-type MMTV integration site family, member 11, related 0.481
mapk6 mitogen-activated protein kinase 6 0.474
myod1 myogenic differentiation 1 0.472
hhip hedgehog interacting protein 0.471
lmo4a LIM domain only 4a 0.461
egr1 early growth response 1 0.453
lef1 lymphocyte enhancer binding factor 1 0.423
epha4a eph receptor A4a 0.418
tll1 tolloid-like 1 0.399
sbno1 strawberry notch homolog 1 (Drosophila) 0.393
axin1 axin 1 0.388
mcl1b myeloid cell leukemia sequence 1b 0.387
znf703 zinc finger protein 703 0.385
smad9 MAD homolog 9 (Drosophila) 0.384
ldb1a LIM-domain binding factor 1a 0.372
col27a1a collagen, type XXVII, alpha 1a 0.368
nrg1 neuregulin 1 0.367
nr3c1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.364
smad1 MAD homolog 1 (Drosophila) 0.358
cav1 caveolin 1 0.355
tfap2c transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) 0.348
lmna lamin A 0.327
runx2a runt-related transcription factor 2a 0.326
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.322
nkx2.2a NK2 transcription factor related 2a 0.320
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.319
nrg2a neuregulin 2a 0.316
notch3 notch homolog 3 0.310
jag2 jagged 2 0.309
oprm1 opioid receptor, mu 1 0.309
met met proto-oncogene (hepatocyte growth factor receptor) 0.298
dlat dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex) 0.296
arhgef7b Rho guanine nucleotide exchange factor (GEF) 7b 0.285
pnx posterior neuron-specific homeobox 0.282
ntn2 netrin 2 0.281
lhx2b LIM homeobox 2b 0.276
slit3 slit (Drosophila) homolog 3 0.276
sox11b SRY-box containing gene 11b 0.271
csnk1db casein kinase 1, delta b 0.271
ddx46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 0.270
gro1 groucho 1 0.269
stk11 serine/threonine kinase 11 0.262
akt2 v-akt murine thymoma viral oncogene homolog 2 0.260
tnfsf10l2 tumor necrosis factor (ligand) superfamily, member 10 like 2 0.259
kpna2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.258
ptprf protein tyrosine phosphatase, receptor type, F 0.256
il17rd interleukin 17 receptor D 0.252
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.249
zgc:101606 zgc:101606 0.247
furina furin (paired basic amino acid cleaving enzyme) a 0.244
zgc:109901 zgc:109901 0.243
odc1 ornithine decarboxylase 1 0.241
fzd5 frizzled homolog 5 0.241
sulf1 sulfatase 1 0.239
pdgfaa platelet-derived growth factor alpha a 0.230
tgfb2 transforming growth factor, beta 2 0.229
zgc:111944 zgc:111944 0.229
dusp1 dual specificity phosphatase 1 0.229
runx1 runt-related transcription factor 1 0.229
rab11fip4a RAB11 family interacting protein 4 (class II) a 0.227
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.227
si:ch211-212m21.5 si:ch211-212m21.5 0.226
gli1 GLI-Kruppel family member 1 0.220
tbx1 T-box 1 0.214
fes feline sarcoma oncogene 0.213
xrcc5 X-ray repair complementing defective repair in Chinese hamster cells 5 0.212
fgfr1a fibroblast growth factor receptor 1a 0.212
vdra vitamin D receptor a 0.211
esrra estrogen-related receptor alpha 0.210
khdrbs1b KH domain containing, RNA binding, signal transduction associated 1b 0.209
LOC100003514 protein kinase C alpha type-like 0.208
wnt5b wingless-type MMTV integration site family, member 5b 0.206
gdf6a growth differentiation factor 6a 0.206
wu:fa27a01 wu:fa27a01 0.206
nr5a5 nuclear receptor subfamily 5, group A, member 5 0.206
zgc:158252 zgc:158252 0.204
flot2a flotillin 2a 0.204
zmynd11 zinc finger, MYND domain containing 11 0.202
dkk1b dickkopf 1b 0.201
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Lam Lamin 0.946
Mad Mothers against dpp 0.923
Akt1 CG4006 gene product from transcript CG4006-RA 0.841
aop anterior open 0.832
Mer Merlin 0.782
dm diminutive 0.768
Tl Toll 0.734
Stat92E Signal-transducer and activator of transcription protein at 92E 0.729
scny scrawny 0.706
l(2)gl lethal (2) giant larvae 0.658
ex expanded 0.641
per period 0.601
arm armadillo 0.593
dco discs overgrown 0.591
pyd polychaetoid 0.578
smo smoothened 0.573
slmb supernumerary limbs 0.571
ci cubitus interruptus 0.559
Caf1 Chromatin assembly factor 1 subunit 0.542
Sir2 CG5216 gene product from transcript CG5216-RA 0.517
tum tumbleweed 0.470
Smox Smad on X 0.397
ft fat 0.396
Egfr Epidermal growth factor receptor 0.375
aux auxillin 0.372
ed echinoid 0.365
pan pangolin 0.353
EcR Ecdysone receptor 0.325
Pka-C1 cAMP-dependent protein kinase 1 0.295
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.284
ash2 absent, small, or homeotic discs 2 0.284
ptc patched 0.282
Ras85D Ras oncogene at 85D 0.249
wg wingless 0.244
Dat Dopamine N acetyltransferase 0.242
hpo hippo 0.242
Nup153 Nucleoporin 153 0.235
sd scalloped 0.222
Nup98 Nucleoporin 98 0.211
Moe Moesin 0.203
aPKC atypical protein kinase C 0.194
fz frizzled 0.192
Nup214 Nucleoporin 214 0.187
argos CG4531 gene product from transcript CG4531-RA 0.186
Ric Ras which interacts with Calmodulin 0.184
yki yorkie 0.183
shg shotgun 0.177
Dl Delta 0.176
shn schnurri 0.175
pum pumilio 0.175
Rel Relish 0.169
tws twins 0.168
Cul-2 Cullin-2 0.160
hth homothorax 0.156
Parp Poly-(ADP-ribose) polymerase 0.154
rin rasputin 0.153
tral trailer hitch 0.152
Pten CG5671 gene product from transcript CG5671-RB 0.149
ec echinus 0.144
so sine oculis 0.142
sina seven in absentia 0.142
Myb Myb oncogene-like 0.140
l(1)dd4 lethal (1) discs degenerate 4 0.139
norpA no receptor potential A 0.135
Gug Grunge 0.134
ago archipelago 0.133
gro groucho 0.132
put punt 0.131
ds dachsous 0.130
CycE Cyclin E 0.130
Act87E Actin 87E 0.125
Socs36E Suppressor of cytokine signaling at 36E 0.122
eya eyes absent 0.121
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.119
RanGap Ran GTPase activating protein 0.118
nmo nemo 0.118
Bj1 Bj1 protein 0.117
ctp cut up 0.116
Dsor1 Downstream of raf1 0.110
baz bazooka 0.108
CSN4 COP9 complex homolog subunit 4 0.107
Su(H) Suppressor of Hairless 0.106
pnt pointed 0.106
Toll-7 CG8595 gene product from transcript CG8595-RA 0.106
ovo CG6824 gene product from transcript CG6824-RE 0.105
Axn Axin 0.103
Med Medea 0.102
sra sarah 0.100
mxc multi sex combs 0.098
CG11943 CG11943 gene product from transcript CG11943-RB 0.096
dally division abnormally delayed 0.091
Pp2B-14D Protein phosphatase 2B at 14D 0.089
cact cactus 0.088
Npc1a Niemann-Pick type C-1a 0.088
Hcf Host cell factor 0.088
spi spitz 0.086
hh hedgehog 0.085
RpII215 RNA polymerase II 215kD subunit 0.084
nkd naked cuticle 0.084
CSN3 COP9 complex homolog subunit 3 0.083
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.998
GSK3B glycogen synthase kinase 3 beta 0.997
KPNB1 karyopherin (importin) beta 1 0.992
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.986
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.982
APC adenomatous polyposis coli 0.970
ESR1 estrogen receptor 1 0.969
SH3KBP1 SH3-domain kinase binding protein 1 0.955
SMAD3 SMAD family member 3 0.944
SMAD7 SMAD family member 7 0.926
PML promyelocytic leukemia 0.926
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.907
GRB2 growth factor receptor-bound protein 2 0.875
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.872
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.865
ARRB1 arrestin, beta 1 0.864
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.841
EGFR epidermal growth factor receptor 0.833
AXIN1 axin 1 0.829
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.826
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.822
SMAD2 SMAD family member 2 0.818
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.814
NUP153 nucleoporin 153kDa 0.765
BTRC beta-transducin repeat containing 0.763
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.759
SMAD1 SMAD family member 1 0.741
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.721
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.698
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.694
IQGAP1 IQ motif containing GTPase activating protein 1 0.686
JUN jun proto-oncogene 0.659
VCP valosin containing protein 0.659
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.646
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.635
DTX3L deltex 3-like (Drosophila) 0.632
TP53 tumor protein p53 0.627
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.608
RELB v-rel reticuloendotheliosis viral oncogene homolog B 0.578
SRPK2 SRSF protein kinase 2 0.569
CSNK1E casein kinase 1, epsilon 0.564
FHL1 four and a half LIM domains 1 0.561
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.551
TOP2A topoisomerase (DNA) II alpha 170kDa 0.522
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.510
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.507
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.506
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.506
BMPR1A bone morphogenetic protein receptor, type IA 0.506
DDR2 discoidin domain receptor tyrosine kinase 2 0.497
WWP2 WW domain containing E3 ubiquitin protein ligase 2 0.493
RAN RAN, member RAS oncogene family 0.487
AKR1C2 aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III) 0.485
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.482
SP1 Sp1 transcription factor 0.478
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy 0.476
MAPK1 mitogen-activated protein kinase 1 0.471
CFLAR CASP8 and FADD-like apoptosis regulator 0.469
LAT linker for activation of T cells 0.461
ATF3 activating transcription factor 3 0.443
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.439
YAP1 Yes-associated protein 1 0.436
DCAF7 DDB1 and CUL4 associated factor 7 0.416
CCL4 chemokine (C-C motif) ligand 4 0.415
BCL3 B-cell CLL/lymphoma 3 0.414
IL1B interleukin 1, beta 0.412
AKR1C1 aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) 0.410
RNF11 ring finger protein 11 0.397
COL1A1 collagen, type I, alpha 1 0.391
DAXX death-domain associated protein 0.389
IL1R1 interleukin 1 receptor, type I 0.371
SIRT1 sirtuin 1 0.369
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.365
SYNE1 spectrin repeat containing, nuclear envelope 1 0.353
SH2D4A SH2 domain containing 4A 0.351
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.349
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.348
RACGAP1 Rac GTPase activating protein 1 0.344
ZNF512B zinc finger protein 512B 0.340
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.339
FKBP1A FK506 binding protein 1A, 12kDa 0.337
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme 0.337
TNIP2 TNFAIP3 interacting protein 2 0.336
CCR5 chemokine (C-C motif) receptor 5 0.335
CUL2 cullin 2 0.329
GRB7 growth factor receptor-bound protein 7 0.325
STAT1 signal transducer and activator of transcription 1, 91kDa 0.316
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.314
FYN FYN oncogene related to SRC, FGR, YES 0.312
NCF1 neutrophil cytosolic factor 1 0.312
MYH9 myosin, heavy chain 9, non-muscle 0.308
UBXN7 UBX domain protein 7 0.307
JAK2 Janus kinase 2 0.304
CKAP5 cytoskeleton associated protein 5 0.303
COL1A2 collagen, type I, alpha 2 0.299
SRPK1 SRSF protein kinase 1 0.295
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 0.293
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.293
PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide 0.289
FOS FBJ murine osteosarcoma viral oncogene homolog 0.286
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.156
Fkbp4 FK506 binding protein 4 0.071
Gria2 glutamate receptor, ionotropic, AMPA 2 0.054
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.052
LOC100364212 heterogeneous nuclear ribonucleoprotein K-like 0.047
Rara retinoic acid receptor, alpha 0.044
Tuba1c tubulin, alpha 1C 0.044
Irs1 insulin receptor substrate 1 0.042
Nrd1 nardilysin 1 0.041
Eef2 eukaryotic translation elongation factor 2 0.040
Mprip myosin phosphatase Rho interacting protein 0.038
Ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 0.037
Stip1 stress-induced phosphoprotein 1 0.037
Casp2 caspase 2 0.035
Smad7 SMAD family member 7 0.034
Tnks2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.034
Pabpc1 poly(A) binding protein, cytoplasmic 1 0.033
Ubb ubiquitin B 0.032
Pdia3 protein disulfide isomerase family A, member 3 0.031
Tat tyrosine aminotransferase 0.031
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.031
Pfn1 profilin 1 0.029
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 0.029
Stat6 signal transducer and activator of transcription 6 0.029
Actg1 actin, gamma 1 0.029
Myadm myeloid-associated differentiation marker 0.028
Myo1c myosin IC 0.027
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.027
Icam1 intercellular adhesion molecule 1 0.027
Pctk2 PCTAIRE protein kinase 2 0.027
Gria3 glutamate receptor, ionotrophic, AMPA 3 0.026
Hspa8 heat shock protein 8 0.026
Ehmt2 euchromatic histone lysine N-methyltransferase 2 0.025
Gdi2 GDP dissociation inhibitor 2 0.025
Jak1 Janus kinase 1 0.025
Ube2a ubiquitin-conjugating enzyme E2A (RAD6 homolog) 0.024
Ctbp1 C-terminal binding protein 1 0.024
Gucy1a3 guanylate cyclase 1, soluble, alpha 3 0.024
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.024
Uba1 ubiquitin-like modifier activating enzyme 1 0.024
Psmb2 proteasome (prosome, macropain) subunit, beta type 2 0.024
Hsp90b1 heat shock protein 90, beta, member 1 0.024
Cyp4f4 cytochrome P450, family 4, subfamily f, polypeptide 4 0.023
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.023
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.023
Gulo gulonolactone (L-) oxidase 0.023
Akt1 v-akt murine thymoma viral oncogene homolog 1 0.023
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.023
Nfia nuclear factor I/A 0.023
Bap1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) 0.023
Cyfip2 cytoplasmic FMR1 interacting protein 2 0.023
Mapk1 mitogen activated protein kinase 1 0.022
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.022
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.022
Thop1 thimet oligopeptidase 1 0.022
Mapk9 mitogen-activated protein kinase 9 0.022
Fkbp1a FK506 binding protein 1a 0.022
Rbck1 RanBP-type and C3HC4-type zinc finger containing 1 0.022
Hnrpd heterogeneous nuclear ribonucleoprotein D 0.021
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.021
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.021
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit 0.021
Cyp2b12 cytochrome P450, family 2, subfamily b, polypeptide 12 0.021
Pla2g5 phospholipase A2, group V 0.021
Pard3 par-3 (partitioning defective 3) homolog (C. elegans) 0.021
Fzd2 frizzled homolog 2 (Drosophila) 0.021
Dmgdh dimethylglycine dehydrogenase 0.020
Bat3 HLA-B-associated transcript 3 0.020
Prdm2 PR domain containing 2, with ZNF domain 0.020
Gria1 glutamate receptor, ionotropic, AMPA 1 0.020
Snap91 synaptosomal-associated protein 91 0.020
Slit3 slit homolog 3 (Drosophila) 0.020
Ppp2cb protein phosphatase 2, catalytic subunit, beta isoform 0.020
Kif1b kinesin family member 1B 0.020
Arf1 ADP-ribosylation factor 1 0.020
Gstm2 glutathione S-transferase mu 2 0.019
Cdc42 cell division cycle 42 (GTP binding protein) 0.019
Socs3 suppressor of cytokine signaling 3 0.019
Jtb jumping translocation breakpoint 0.019
Serpina4 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4 0.019
Tceb3 transcription elongation factor B (SIII), polypeptide 3 0.019
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.019
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.019
Vegfa vascular endothelial growth factor A 0.019
Hspd1 heat shock protein 1 (chaperonin) 0.019
Pdcd4 programmed cell death 4 0.019
Thra thyroid hormone receptor alpha 0.018
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.018
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.018
Zfp36 zinc finger protein 36 0.018
Twist2 twist homolog 2 (Drosophila) 0.018
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.018
Camkk2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.018
Alb albumin 0.018
Nudt3 nudix (nucleoside diphosphate linked moiety X)-type motif 3 0.018
Pkn2 protein kinase N2 0.018
Set SET nuclear oncogene 0.018
Actb actin, beta 0.018
Ppp2r2a protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha isoform 0.017
Jak2 Janus kinase 2 0.017
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
NSP1 Nsp1p 0.997
PSE1 Pse1p 0.996
KAP95 Kap95p 0.993
NUP49 Nup49p 0.990
NUP116 Nup116p 0.984
GSP1 Gsp1p 0.967
GLE1 Gle1p 0.911
NIC96 Nic96p 0.895
NUP170 Nup170p 0.859
CSE1 Cse1p 0.855
NUP100 Nup100p 0.845
NUP57 Nup57p 0.843
NUP133 Nup133p 0.802
NUP1 Nup1p 0.760
NUP60 Nup60p 0.739
MTR10 Mtr10p 0.729
SIS1 Sis1p 0.719
NUP2 Nup2p 0.703
NUP145 Nup145p 0.646
SHP1 Shp1p 0.623
NUP120 Nup120p 0.616
NUP157 Nup157p 0.613
CLA4 Cla4p 0.593
NAP1 Nap1p 0.557
CRM1 Crm1p 0.509
PBS2 Pbs2p 0.503
NDC1 Ndc1p 0.493
MEX67 Mex67p 0.479
CNB1 Cnb1p 0.459
ROM2 Rom2p 0.458
NUP82 Nup82p 0.436
RNR2 Rnr2p 0.429
NUP192 Nup192p 0.423
BMH1 Bmh1p 0.397
NUP53 Nup53p 0.394
STI1 Sti1p 0.385
SLT2 Slt2p 0.379
SRP1 Srp1p 0.344
BOI2 Boi2p 0.338
POM34 Pom34p 0.334
KAP123 Kap123p 0.322
CKA2 Cka2p 0.317
MSG5 Msg5p 0.313
RNA1 Rna1p 0.299
RTT107 Rtt107p 0.297
FUS3 Fus3p 0.293
NUP188 Nup188p 0.290
CMD1 Cmd1p 0.270
ASM4 Asm4p 0.261
RPN2 Rpn2p 0.259
NUP85 Nup85p 0.254
SSA4 Ssa4p 0.253
APJ1 Apj1p 0.242
OTU1 Otu1p 0.241
RNR4 Rnr4p 0.241
TRA1 Tra1p 0.224
STE5 Ste5p 0.203
SLX9 Slx9p 0.200
STE11 Ste11p 0.192
GLE2 Gle2p 0.191
TOP2 Top2p 0.190
SRM1 Srm1p 0.189
KDX1 Kdx1p 0.187
HRP1 Hrp1p 0.187
ECM29 Ecm29p 0.186
KAP104 Kap104p 0.172
POM152 Pom152p 0.165
KSP1 Ksp1p 0.160
TOR1 Tor1p 0.155
ATG13 Atg13p 0.154
ACC1 Acc1p 0.150
OSH6 Osh6p 0.150
STE20 Ste20p 0.146
KAP114 Kap114p 0.144
LOS1 Los1p 0.143
CLB6 Clb6p 0.138
CTK3 Ctk3p 0.137
RHO1 Rho1p 0.131
REI1 Rei1p 0.121
VAC14 Vac14p 0.121
YOR262W hypothetical protein 0.116
CNA1 Cna1p 0.116
SAC3 Sac3p 0.115
WTM2 Wtm2p 0.115
CDC55 Cdc55p 0.114
NTO1 Nto1p 0.111
SOK1 Sok1p 0.110
DAL80 Dal80p 0.110
YRB1 Yrb1p 0.107
TCO89 Tco89p 0.107
SWC7 Swc7p 0.106
BUL1 Bul1p 0.104
RCN1 Rcn1p 0.103
RPT4 Rpt4p 0.102
MEP2 Mep2p 0.101
ARP3 Arp3p 0.099
TPD3 Tpd3p 0.099
PPQ1 Ppq1p 0.099
TWF1 Twf1p 0.096
YAP1 Yap1p 0.096