Process View
The network for 'regulation of astrocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of astrocyte differentiation.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
Shh | sonic hedgehog | 1.000 | |
Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
Bmp4 | bone morphogenetic protein 4 | 1.000 | |
Pax3 | paired box gene 3 | 1.000 | |
Sox9 | SRY-box containing gene 9 | 1.000 | |
Foxc1 | forkhead box C1 | 0.999 | |
Notch1 | Notch gene homolog 1 (Drosophila) | 0.999 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.998 | |
Tcfap2a | transcription factor AP-2, alpha | 0.996 | |
Prrx1 | paired related homeobox 1 | 0.996 | |
Pax6 | paired box gene 6 | 0.995 | |
Tgfb2 | transforming growth factor, beta 2 | 0.995 | |
Fgf8 | fibroblast growth factor 8 | 0.995 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.995 | |
Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.994 | |
Smo | smoothened homolog (Drosophila) | 0.993 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.992 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.991 | |
Chrd | chordin | 0.988 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.986 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.985 | |
Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.985 | |
Sox2 | SRY-box containing gene 2 | 0.984 | |
Foxg1 | forkhead box G1 | 0.984 | |
Emx1 | empty spiracles homolog 1 (Drosophila) | 0.979 | |
Dlx5 | distal-less homeobox 5 | 0.969 | |
Id3 | inhibitor of DNA binding 3 | 0.969 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.964 | |
Msx1 | homeobox, msh-like 1 | 0.957 | |
Efnb2 | ephrin B2 | 0.957 | |
Tbx1 | T-box 1 | 0.954 | |
Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.951 | |
Foxc2 | forkhead box C2 | 0.949 | |
Ptch1 | patched homolog 1 | 0.948 | |
Psen1 | presenilin 1 | 0.923 | |
Acvr1 | activin A receptor, type 1 | 0.916 | |
Ret | ret proto-oncogene | 0.883 | |
Gli2 | GLI-Kruppel family member GLI2 | 0.864 | |
Gbx2 | gastrulation brain homeobox 2 | 0.847 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.834 | |
Pax2 | paired box gene 2 | 0.827 | |
Id1 | inhibitor of DNA binding 1 | 0.827 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.820 | |
Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.814 | |
Jag1 | jagged 1 | 0.813 | |
Chd7 | chromodomain helicase DNA binding protein 7 | 0.810 | |
Pbx1 | pre B-cell leukemia transcription factor 1 | 0.806 | |
Gsc | goosecoid homeobox | 0.780 | |
Itgb1 | integrin beta 1 (fibronectin receptor beta) | 0.763 | |
Prrx2 | paired related homeobox 2 | 0.762 | |
Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.747 | |
Hoxa1 | homeobox A1 | 0.738 | |
Sox11 | SRY-box containing gene 11 | 0.723 | |
Vegfa | vascular endothelial growth factor A | 0.697 | |
Erbb3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.684 | |
Rarb | retinoic acid receptor, beta | 0.675 | |
Dcx | doublecortin | 0.673 | |
Nodal | nodal | 0.666 | |
Dlx6 | distal-less homeobox 6 | 0.663 | |
Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.633 | |
Ephb2 | Eph receptor B2 | 0.626 | |
Rarg | retinoic acid receptor, gamma | 0.623 | |
Pitx2 | paired-like homeodomain transcription factor 2 | 0.610 | |
Meox2 | mesenchyme homeobox 2 | 0.586 | |
Hes5 | hairy and enhancer of split 5 (Drosophila) | 0.573 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.568 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.524 | |
Fgf10 | fibroblast growth factor 10 | 0.507 | |
Nog | noggin | 0.484 | |
Msx2 | homeobox, msh-like 2 | 0.464 | |
Bmp7 | bone morphogenetic protein 7 | 0.455 | |
Bdnf | brain derived neurotrophic factor | 0.454 | |
Dll1 | delta-like 1 (Drosophila) | 0.449 | |
Alx4 | aristaless-like homeobox 4 | 0.449 | |
Ednra | endothelin receptor type A | 0.441 | |
Epha4 | Eph receptor A4 | 0.438 | |
Sox4 | SRY-box containing gene 4 | 0.354 | |
Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.344 | |
Sox10 | SRY-box containing gene 10 | 0.343 | |
Dlx2 | distal-less homeobox 2 | 0.338 | |
Ascl1 | achaete-scute complex homolog 1 (Drosophila) | 0.335 | |
Hoxa2 | homeobox A2 | 0.330 | |
Pten | phosphatase and tensin homolog | 0.320 | |
Ntrk2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.291 | |
Lhx5 | LIM homeobox protein 5 | 0.285 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.281 | |
Rara | retinoic acid receptor, alpha | 0.280 | |
Dlx1 | distal-less homeobox 1 | 0.278 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.263 | |
Efnb1 | ephrin B1 | 0.239 | |
Trp53 | transformation related protein 53 | 0.234 | |
Col2a1 | collagen, type II, alpha 1 | 0.232 | |
Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.230 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.229 | |
Foxi3 | forkhead box I3 | 0.219 | |
Rb1 | retinoblastoma 1 | 0.213 | |
Runx2 | runt related transcription factor 2 | 0.199 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.198 | |
Ptprz1 | protein tyrosine phosphatase, receptor type Z, polypeptide 1 | 0.194 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
PLAU | plasminogen activator, urokinase | 0.961 | |
RIN3 | Ras and Rab interactor 3 | 0.955 | |
JAG1 | jagged 1 | 0.904 | |
DNM1 | dynamin 1 | 0.785 | |
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.724 | |
BMPR1A | bone morphogenetic protein receptor, type IA | 0.629 | |
PLAUR | plasminogen activator, urokinase receptor | 0.556 | |
IL1R1 | interleukin 1 receptor, type I | 0.513 | |
ALB | albumin | 0.509 | |
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.501 | |
NOTCH3 | notch 3 | 0.492 | |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.427 | |
RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.411 | |
PLAT | plasminogen activator, tissue | 0.334 | |
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.275 | |
SYNJ1 | synaptojanin 1 | 0.254 | |
TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.219 | |
FGF1 | fibroblast growth factor 1 (acidic) | 0.217 | |
IFNGR1 | interferon gamma receptor 1 | 0.184 | |
BMP7 | bone morphogenetic protein 7 | 0.176 | |
BCAS2 | breast carcinoma amplified sequence 2 | 0.170 | |
SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.168 | |
SNX9 | sorting nexin 9 | 0.166 | |
HIST1H3B | histone cluster 1, H3b | 0.160 | |
MAX | MYC associated factor X | 0.156 | |
MAML1 | mastermind-like 1 (Drosophila) | 0.155 | |
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.153 | |
U2AF2 | U2 small nuclear RNA auxiliary factor 2 | 0.145 | |
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.145 | |
SF3A2 | splicing factor 3a, subunit 2, 66kDa | 0.132 | |
IL8 | interleukin 8 | 0.132 | |
LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.124 | |
PRPF8 | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 0.110 | |
PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.088 | |
IL6R | interleukin 6 receptor | 0.083 | |
IL6 | interleukin 6 (interferon, beta 2) | 0.082 | |
JAK1 | Janus kinase 1 | 0.081 | |
RBM10 | RNA binding motif protein 10 | 0.079 | |
JAK2 | Janus kinase 2 | 0.078 | |
SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.078 | |
FOSL1 | FOS-like antigen 1 | 0.073 | |
OSMR | oncostatin M receptor | 0.072 | |
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.071 | |
SERPINC1 | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 0.069 | |
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.068 | |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.068 | |
LIFR | leukemia inhibitory factor receptor alpha | 0.066 | |
IL1RN | interleukin 1 receptor antagonist | 0.066 | |
JAG2 | jagged 2 | 0.062 | |
ITSN1 | intersectin 1 (SH3 domain protein) | 0.060 | |
BMP2 | bone morphogenetic protein 2 | 0.060 | |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.059 | |
FGA | fibrinogen alpha chain | 0.058 | |
PRCC | papillary renal cell carcinoma (translocation-associated) | 0.057 | |
EGR1 | early growth response 1 | 0.057 | |
FGFR2 | fibroblast growth factor receptor 2 | 0.057 | |
RNPS1 | RNA binding protein S1, serine-rich domain | 0.057 | |
ICAM1 | intercellular adhesion molecule 1 | 0.053 | |
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.052 | |
CCL20 | chemokine (C-C motif) ligand 20 | 0.052 | |
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.051 | |
FSTL1 | follistatin-like 1 | 0.049 | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.047 | |
SLC4A1 | solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) | 0.045 | |
TAL1 | T-cell acute lymphocytic leukemia 1 | 0.044 | |
NOG | noggin | 0.044 | |
DLL1 | delta-like 1 (Drosophila) | 0.042 | |
NOTCH2 | notch 2 | 0.041 | |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.041 | |
OLIG2 | oligodendrocyte lineage transcription factor 2 | 0.040 | |
SPHK1 | sphingosine kinase 1 | 0.039 | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.039 | |
CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.039 | |
IGF1R | insulin-like growth factor 1 receptor | 0.036 | |
ZC3H12A | zinc finger CCCH-type containing 12A | 0.035 | |
CDK6 | cyclin-dependent kinase 6 | 0.034 | |
SUGP1 | SURP and G patch domain containing 1 | 0.034 | |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.033 | |
IER3 | immediate early response 3 | 0.033 | |
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.032 | |
CCL2 | chemokine (C-C motif) ligand 2 | 0.032 | |
SOCS3 | suppressor of cytokine signaling 3 | 0.031 | |
SH3GL2 | SH3-domain GRB2-like 2 | 0.031 | |
SF3B3 | splicing factor 3b, subunit 3, 130kDa | 0.030 | |
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.030 | |
F3 | coagulation factor III (thromboplastin, tissue factor) | 0.029 | |
SMAD7 | SMAD family member 7 | 0.029 | |
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.029 | |
BCL2A1 | BCL2-related protein A1 | 0.028 | |
GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.028 | |
SF3B4 | splicing factor 3b, subunit 4, 49kDa | 0.028 | |
HIST1H4F | histone cluster 1, H4f | 0.027 | |
KRT8 | keratin 8 | 0.027 | |
SART1 | squamous cell carcinoma antigen recognized by T cells | 0.026 | |
GPKOW | G patch domain and KOW motifs | 0.026 | |
INHBA | inhibin, beta A | 0.026 | |
RUNX1 | runt-related transcription factor 1 | 0.025 | |
SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.025 | |
SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.025 | |
NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.024 |