The network for 'regulation of astrocyte differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of astrocyte differentiation

Any process that modulates the frequency, rate or extent of astrocyte differentiation.

Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 1.000
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 1.000
Bmp4 bone morphogenetic protein 4 1.000
Pax3 paired box gene 3 1.000
Sox9 SRY-box containing gene 9 1.000
Foxc1 forkhead box C1 0.999
Notch1 Notch gene homolog 1 (Drosophila) 0.999
Otx2 orthodenticle homolog 2 (Drosophila) 0.998
Tcfap2a transcription factor AP-2, alpha 0.996
Prrx1 paired related homeobox 1 0.996
Pax6 paired box gene 6 0.995
Tgfb2 transforming growth factor, beta 2 0.995
Fgf8 fibroblast growth factor 8 0.995
Eya1 eyes absent 1 homolog (Drosophila) 0.995
Isl1 ISL1 transcription factor, LIM/homeodomain 0.994
Smo smoothened homolog (Drosophila) 0.993
Fgfr1 fibroblast growth factor receptor 1 0.992
Ctnnb1 catenin (cadherin associated protein), beta 1 0.991
Chrd chordin 0.988
Hand2 heart and neural crest derivatives expressed transcript 2 0.986
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.985
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.985
Sox2 SRY-box containing gene 2 0.984
Foxg1 forkhead box G1 0.984
Emx1 empty spiracles homolog 1 (Drosophila) 0.979
Dlx5 distal-less homeobox 5 0.969
Id3 inhibitor of DNA binding 3 0.969
Hand1 heart and neural crest derivatives expressed transcript 1 0.964
Msx1 homeobox, msh-like 1 0.957
Efnb2 ephrin B2 0.957
Tbx1 T-box 1 0.954
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.951
Foxc2 forkhead box C2 0.949
Ptch1 patched homolog 1 0.948
Psen1 presenilin 1 0.923
Acvr1 activin A receptor, type 1 0.916
Ret ret proto-oncogene 0.883
Gli2 GLI-Kruppel family member GLI2 0.864
Gbx2 gastrulation brain homeobox 2 0.847
Emx2 empty spiracles homolog 2 (Drosophila) 0.834
Pax2 paired box gene 2 0.827
Id1 inhibitor of DNA binding 1 0.827
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.820
Hes1 hairy and enhancer of split 1 (Drosophila) 0.814
Jag1 jagged 1 0.813
Chd7 chromodomain helicase DNA binding protein 7 0.810
Pbx1 pre B-cell leukemia transcription factor 1 0.806
Gsc goosecoid homeobox 0.780
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.763
Prrx2 paired related homeobox 2 0.762
Rbpj recombination signal binding protein for immunoglobulin kappa J region 0.747
Hoxa1 homeobox A1 0.738
Sox11 SRY-box containing gene 11 0.723
Vegfa vascular endothelial growth factor A 0.697
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.684
Rarb retinoic acid receptor, beta 0.675
Dcx doublecortin 0.673
Nodal nodal 0.666
Dlx6 distal-less homeobox 6 0.663
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.633
Ephb2 Eph receptor B2 0.626
Rarg retinoic acid receptor, gamma 0.623
Pitx2 paired-like homeodomain transcription factor 2 0.610
Meox2 mesenchyme homeobox 2 0.586
Hes5 hairy and enhancer of split 5 (Drosophila) 0.573
Zeb1 zinc finger E-box binding homeobox 1 0.568
Vangl2 vang-like 2 (van gogh, Drosophila) 0.524
Fgf10 fibroblast growth factor 10 0.507
Nog noggin 0.484
Msx2 homeobox, msh-like 2 0.464
Bmp7 bone morphogenetic protein 7 0.455
Bdnf brain derived neurotrophic factor 0.454
Dll1 delta-like 1 (Drosophila) 0.449
Alx4 aristaless-like homeobox 4 0.449
Ednra endothelin receptor type A 0.441
Epha4 Eph receptor A4 0.438
Sox4 SRY-box containing gene 4 0.354
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.344
Sox10 SRY-box containing gene 10 0.343
Dlx2 distal-less homeobox 2 0.338
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.335
Hoxa2 homeobox A2 0.330
Pten phosphatase and tensin homolog 0.320
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.291
Lhx5 LIM homeobox protein 5 0.285
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.281
Rara retinoic acid receptor, alpha 0.280
Dlx1 distal-less homeobox 1 0.278
Zic3 zinc finger protein of the cerebellum 3 0.263
Efnb1 ephrin B1 0.239
Trp53 transformation related protein 53 0.234
Col2a1 collagen, type II, alpha 1 0.232
Hey2 hairy/enhancer-of-split related with YRPW motif 2 0.230
Notch2 Notch gene homolog 2 (Drosophila) 0.229
Foxi3 forkhead box I3 0.219
Rb1 retinoblastoma 1 0.213
Runx2 runt related transcription factor 2 0.199
Otx1 orthodenticle homolog 1 (Drosophila) 0.198
Ptprz1 protein tyrosine phosphatase, receptor type Z, polypeptide 1 0.194
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
PLAU plasminogen activator, urokinase 0.961
RIN3 Ras and Rab interactor 3 0.955
JAG1 jagged 1 0.904
DNM1 dynamin 1 0.785
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.724
BMPR1A bone morphogenetic protein receptor, type IA 0.629
PLAUR plasminogen activator, urokinase receptor 0.556
IL1R1 interleukin 1 receptor, type I 0.513
ALB albumin 0.509
EFTUD2 elongation factor Tu GTP binding domain containing 2 0.501
NOTCH3 notch 3 0.492
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.427
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.411
PLAT plasminogen activator, tissue 0.334
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.275
SYNJ1 synaptojanin 1 0.254
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.219
FGF1 fibroblast growth factor 1 (acidic) 0.217
IFNGR1 interferon gamma receptor 1 0.184
BMP7 bone morphogenetic protein 7 0.176
BCAS2 breast carcinoma amplified sequence 2 0.170
SF3A1 splicing factor 3a, subunit 1, 120kDa 0.168
SNX9 sorting nexin 9 0.166
HIST1H3B histone cluster 1, H3b 0.160
MAX MYC associated factor X 0.156
MAML1 mastermind-like 1 (Drosophila) 0.155
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A 0.153
U2AF2 U2 small nuclear RNA auxiliary factor 2 0.145
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.145
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.132
IL8 interleukin 8 0.132
LIF leukemia inhibitory factor (cholinergic differentiation factor) 0.124
PRPF8 PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) 0.110
PRPF6 PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) 0.088
IL6R interleukin 6 receptor 0.083
IL6 interleukin 6 (interferon, beta 2) 0.082
JAK1 Janus kinase 1 0.081
RBM10 RNA binding motif protein 10 0.079
JAK2 Janus kinase 2 0.078
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5) 0.078
FOSL1 FOS-like antigen 1 0.073
OSMR oncostatin M receptor 0.072
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.071
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.069
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 0.068
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.068
LIFR leukemia inhibitory factor receptor alpha 0.066
IL1RN interleukin 1 receptor antagonist 0.066
JAG2 jagged 2 0.062
ITSN1 intersectin 1 (SH3 domain protein) 0.060
BMP2 bone morphogenetic protein 2 0.060
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.059
FGA fibrinogen alpha chain 0.058
PRCC papillary renal cell carcinoma (translocation-associated) 0.057
EGR1 early growth response 1 0.057
FGFR2 fibroblast growth factor receptor 2 0.057
RNPS1 RNA binding protein S1, serine-rich domain 0.057
ICAM1 intercellular adhesion molecule 1 0.053
IL6ST interleukin 6 signal transducer (gp130, oncostatin M receptor) 0.052
CCL20 chemokine (C-C motif) ligand 20 0.052
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.051
FSTL1 follistatin-like 1 0.049
MYC v-myc myelocytomatosis viral oncogene homolog (avian) 0.047
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.045
TAL1 T-cell acute lymphocytic leukemia 1 0.044
NOG noggin 0.044
DLL1 delta-like 1 (Drosophila) 0.042
NOTCH2 notch 2 0.041
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.041
OLIG2 oligodendrocyte lineage transcription factor 2 0.040
SPHK1 sphingosine kinase 1 0.039
CXCL2 chemokine (C-X-C motif) ligand 2 0.039
CYR61 cysteine-rich, angiogenic inducer, 61 0.039
IGF1R insulin-like growth factor 1 receptor 0.036
ZC3H12A zinc finger CCCH-type containing 12A 0.035
CDK6 cyclin-dependent kinase 6 0.034
SUGP1 SURP and G patch domain containing 1 0.034
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.033
IER3 immediate early response 3 0.033
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.032
CCL2 chemokine (C-C motif) ligand 2 0.032
SOCS3 suppressor of cytokine signaling 3 0.031
SH3GL2 SH3-domain GRB2-like 2 0.031
SF3B3 splicing factor 3b, subunit 3, 130kDa 0.030
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.030
F3 coagulation factor III (thromboplastin, tissue factor) 0.029
SMAD7 SMAD family member 7 0.029
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.029
BCL2A1 BCL2-related protein A1 0.028
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.028
SF3B4 splicing factor 3b, subunit 4, 49kDa 0.028
HIST1H4F histone cluster 1, H4f 0.027
KRT8 keratin 8 0.027
SART1 squamous cell carcinoma antigen recognized by T cells 0.026
GPKOW G patch domain and KOW motifs 0.026
INHBA inhibin, beta A 0.026
RUNX1 runt-related transcription factor 1 0.025
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1 0.025
SF3B2 splicing factor 3b, subunit 2, 145kDa 0.025
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.024
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism