IMP
Process View
The network for 'his purkinje system cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
his purkinje system cell differentiation
The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.999 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.999 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.998 | |
| Tbx5 | T-box 5 | 0.997 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.996 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.992 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.992 | |
| Sox9 | SRY-box containing gene 9 | 0.991 | |
| Fgf8 | fibroblast growth factor 8 | 0.987 | |
| Tbx3 | T-box 3 | 0.976 | |
| Prrx1 | paired related homeobox 1 | 0.944 | |
| Msx1 | homeobox, msh-like 1 | 0.927 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.921 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.920 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.920 | |
| Bmp4 | bone morphogenetic protein 4 | 0.919 | |
| Gata4 | GATA binding protein 4 | 0.908 | |
| Foxc2 | forkhead box C2 | 0.902 | |
| Hoxa1 | homeobox A1 | 0.899 | |
| Foxc1 | forkhead box C1 | 0.870 | |
| Pax3 | paired box gene 3 | 0.844 | |
| Gja5 | gap junction protein, alpha 5 | 0.803 | |
| Tbx1 | T-box 1 | 0.797 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.791 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.784 | |
| Dlx5 | distal-less homeobox 5 | 0.774 | |
| Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.751 | |
| Runx2 | runt related transcription factor 2 | 0.726 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.693 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.618 | |
| Nkx3-2 | NK3 homeobox 2 | 0.608 | |
| Jag1 | jagged 1 | 0.599 | |
| Foxg1 | forkhead box G1 | 0.589 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.585 | |
| Fgf10 | fibroblast growth factor 10 | 0.566 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.556 | |
| Sall4 | sal-like 4 (Drosophila) | 0.553 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.548 | |
| Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.526 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.523 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.480 | |
| Pax9 | paired box gene 9 | 0.478 | |
| Gata6 | GATA binding protein 6 | 0.450 | |
| Ighmbp2 | immunoglobulin mu binding protein 2 | 0.439 | |
| Gsc | goosecoid homeobox | 0.432 | |
| Foxh1 | forkhead box H1 | 0.405 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.391 | |
| T | brachyury | 0.365 | |
| Msx2 | homeobox, msh-like 2 | 0.353 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.352 | |
| Alx3 | aristaless-like homeobox 3 | 0.348 | |
| Rarb | retinoic acid receptor, beta | 0.328 | |
| Nkx6-1 | NK6 homeobox 1 | 0.318 | |
| Alx4 | aristaless-like homeobox 4 | 0.314 | |
| Mesp1 | mesoderm posterior 1 | 0.302 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.276 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.260 | |
| Alx1 | ALX homeobox 1 | 0.255 | |
| Dlx2 | distal-less homeobox 2 | 0.247 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.247 | |
| Rxra | retinoid X receptor alpha | 0.245 | |
| Sox2 | SRY-box containing gene 2 | 0.239 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.236 | |
| Tlx3 | T-cell leukemia, homeobox 3 | 0.233 | |
| Chrd | chordin | 0.220 | |
| Pax2 | paired box gene 2 | 0.217 | |
| Vegfa | vascular endothelial growth factor A | 0.209 | |
| Nog | noggin | 0.202 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.202 | |
| Tcf21 | transcription factor 21 | 0.183 | |
| Hoxa13 | homeobox A13 | 0.181 | |
| Hoxd3 | homeobox D3 | 0.173 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.160 | |
| Smo | smoothened homolog (Drosophila) | 0.158 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.158 | |
| Sox11 | SRY-box containing gene 11 | 0.151 | |
| Nodal | nodal | 0.151 | |
| Hoxa3 | homeobox A3 | 0.149 | |
| Lef1 | lymphoid enhancer binding factor 1 | 0.148 | |
| Hoxa2 | homeobox A2 | 0.144 | |
| Hmx3 | H6 homeobox 3 | 0.133 | |
| Pou5f1 | POU domain, class 5, transcription factor 1 | 0.131 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.129 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.128 | |
| Rnf2 | ring finger protein 2 | 0.124 | |
| Ntf3 | neurotrophin 3 | 0.122 | |
| Bmp7 | bone morphogenetic protein 7 | 0.122 | |
| Trp63 | transformation related protein 63 | 0.118 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.117 | |
| Mecom | MDS1 and EVI1 complex locus | 0.115 | |
| Lmx1a | LIM homeobox transcription factor 1 alpha | 0.110 | |
| Efnb2 | ephrin B2 | 0.109 | |
| Mn1 | meningioma 1 | 0.104 | |
| Insm1 | insulinoma-associated 1 | 0.103 | |
| Acvr1 | activin A receptor, type 1 | 0.102 | |
| Prrx2 | paired related homeobox 2 | 0.102 | |
| Pcdh12 | protocadherin 12 | 0.100 | |
| Dlx6 | distal-less homeobox 6 | 0.097 | |
| Bmp5 | bone morphogenetic protein 5 | 0.092 |
