IMP
Process View
The network for 'positive regulation of steroid biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of steroid biosynthetic process
Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Rarg | retinoic acid receptor, gamma | 0.999 | |
| Rarb | retinoic acid receptor, beta | 0.961 | |
| Thra | thyroid hormone receptor alpha | 0.942 | |
| Rxra | retinoid X receptor alpha | 0.917 | |
| Rara | retinoic acid receptor, alpha | 0.812 | |
| Pax8 | paired box gene 8 | 0.798 | |
| Gnas | GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus | 0.692 | |
| Thrb | thyroid hormone receptor beta | 0.657 | |
| Hoxa3 | homeobox A3 | 0.626 | |
| Ece1 | endothelin converting enzyme 1 | 0.549 | |
| Ghr | growth hormone receptor | 0.546 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.452 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.366 | |
| Egfr | epidermal growth factor receptor | 0.341 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.329 | |
| Pax2 | paired box gene 2 | 0.293 | |
| Vegfa | vascular endothelial growth factor A | 0.279 | |
| Ednra | endothelin receptor type A | 0.278 | |
| Grb10 | growth factor receptor bound protein 10 | 0.277 | |
| Foxc1 | forkhead box C1 | 0.265 | |
| Bmp4 | bone morphogenetic protein 4 | 0.255 | |
| Igf2r | insulin-like growth factor 2 receptor | 0.245 | |
| Npc1 | Niemann Pick type C1 | 0.199 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.197 | |
| Lhx1 | LIM homeobox protein 1 | 0.186 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.175 | |
| Dbp | D site albumin promoter binding protein | 0.143 | |
| Acvr1 | activin A receptor, type 1 | 0.140 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.136 | |
| Esr1 | estrogen receptor 1 (alpha) | 0.126 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 0.125 | |
| Cebpa | CCAAT/enhancer binding protein (C/EBP), alpha | 0.124 | |
| Lhx3 | LIM homeobox protein 3 | 0.124 | |
| Agrp | agouti related protein | 0.123 | |
| Abca1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.120 | |
| Duox2 | dual oxidase 2 | 0.120 | |
| Sox4 | SRY-box containing gene 4 | 0.107 | |
| Tef | thyrotroph embryonic factor | 0.101 | |
| Foxc2 | forkhead box C2 | 0.098 | |
| Lyz2 | lysozyme 2 | 0.097 | |
| Bmper | BMP-binding endothelial regulator | 0.096 | |
| Cdkn1c | cyclin-dependent kinase inhibitor 1C (P57) | 0.095 | |
| Il1a | interleukin 1 alpha | 0.094 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.094 | |
| Sox9 | SRY-box containing gene 9 | 0.093 | |
| Nostrin | nitric oxide synthase trafficker | 0.087 | |
| Apoe | apolipoprotein E | 0.080 | |
| Wnt9b | wingless-type MMTV integration site 9B | 0.080 | |
| Ncoa1 | nuclear receptor coactivator 1 | 0.073 | |
| Igf1 | insulin-like growth factor 1 | 0.069 | |
| Dhcr7 | 7-dehydrocholesterol reductase | 0.067 | |
| Casp4 | caspase 4, apoptosis-related cysteine peptidase | 0.067 | |
| Tshr | thyroid stimulating hormone receptor | 0.067 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.057 | |
| Idua | iduronidase, alpha-L- | 0.055 | |
| Plxnd1 | plexin D1 | 0.055 | |
| Csf1 | colony stimulating factor 1 (macrophage) | 0.054 | |
| Fasn | fatty acid synthase | 0.052 | |
| Nr1d1 | nuclear receptor subfamily 1, group D, member 1 | 0.051 | |
| Slc16a2 | solute carrier family 16 (monocarboxylic acid transporters), member 2 | 0.051 | |
| Prdm16 | PR domain containing 16 | 0.050 | |
| Igf1r | insulin-like growth factor I receptor | 0.049 | |
| Chrd | chordin | 0.049 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.049 | |
| Cav1 | caveolin 1, caveolae protein | 0.048 | |
| Gata3 | GATA binding protein 3 | 0.048 | |
| Adam17 | a disintegrin and metallopeptidase domain 17 | 0.044 | |
| Irs2 | insulin receptor substrate 2 | 0.044 | |
| Srf | serum response factor | 0.042 | |
| Fgfrl1 | fibroblast growth factor receptor-like 1 | 0.041 | |
| Nlrp3 | NLR family, pyrin domain containing 3 | 0.040 | |
| Mmp14 | matrix metallopeptidase 14 (membrane-inserted) | 0.039 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.039 | |
| Insr | insulin receptor | 0.038 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.038 | |
| Casp1 | caspase 1 | 0.038 | |
| Gna11 | guanine nucleotide binding protein, alpha 11 | 0.037 | |
| Smo | smoothened homolog (Drosophila) | 0.036 | |
| Smpd3 | sphingomyelin phosphodiesterase 3, neutral | 0.036 | |
| Mvd | mevalonate (diphospho) decarboxylase | 0.036 | |
| Tbx1 | T-box 1 | 0.036 | |
| Cat | catalase | 0.035 | |
| Gpc3 | glypican 3 | 0.033 | |
| Jag1 | jagged 1 | 0.032 | |
| Lepr | leptin receptor | 0.029 | |
| Rxrb | retinoid X receptor beta | 0.029 | |
| Scd1 | stearoyl-Coenzyme A desaturase 1 | 0.028 | |
| Dhcr24 | 24-dehydrocholesterol reductase | 0.027 | |
| Hsd3b7 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 0.027 | |
| Hoxa5 | homeobox A5 | 0.027 | |
| Ret | ret proto-oncogene | 0.027 | |
| Mrc1 | mannose receptor, C type 1 | 0.026 | |
| Nrp1 | neuropilin 1 | 0.026 | |
| Islr | immunoglobulin superfamily containing leucine-rich repeat | 0.026 | |
| Reep6 | receptor accessory protein 6 | 0.025 | |
| Slc25a1 | solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1 | 0.025 | |
| Scd2 | stearoyl-Coenzyme A desaturase 2 | 0.024 | |
| Hr | hairless | 0.024 | |
| Cacna1d | calcium channel, voltage-dependent, L type, alpha 1D subunit | 0.024 | |
| Clip2 | CAP-GLY domain containing linker protein 2 | 0.023 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 1.000 | |
| IL1R1 | interleukin 1 receptor, type I | 0.975 | |
| GH1 | growth hormone 1 | 0.918 | |
| FGF10 | fibroblast growth factor 10 | 0.875 | |
| CSH1 | chorionic somatomammotropin hormone 1 (placental lactogen) | 0.860 | |
| CSHL1 | chorionic somatomammotropin hormone-like 1 | 0.838 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.833 | |
| BMPR1B | bone morphogenetic protein receptor, type IB | 0.442 | |
| IGF2R | insulin-like growth factor 2 receptor | 0.438 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.435 | |
| CSH2 | chorionic somatomammotropin hormone 2 | 0.433 | |
| GH2 | growth hormone 2 | 0.377 | |
| FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.307 | |
| WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.230 | |
| IL1RAP | interleukin 1 receptor accessory protein | 0.206 | |
| IL1B | interleukin 1, beta | 0.180 | |
| ITGB1BP3 | integrin beta 1 binding protein 3 | 0.162 | |
| MYO6 | myosin VI | 0.151 | |
| WNT1 | wingless-type MMTV integration site family, member 1 | 0.121 | |
| MED15 | mediator complex subunit 15 | 0.111 | |
| IL1R2 | interleukin 1 receptor, type II | 0.098 | |
| FGF4 | fibroblast growth factor 4 | 0.097 | |
| IL8 | interleukin 8 | 0.069 | |
| IL1RN | interleukin 1 receptor antagonist | 0.063 | |
| WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.063 | |
| PGRMC1 | progesterone receptor membrane component 1 | 0.054 | |
| FGF18 | fibroblast growth factor 18 | 0.044 | |
| FRS2 | fibroblast growth factor receptor substrate 2 | 0.044 | |
| ACADM | acyl-CoA dehydrogenase, C-4 to C-12 straight chain | 0.040 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.036 | |
| TRADD | TNFRSF1A-associated via death domain | 0.034 | |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.032 | |
| INSR | insulin receptor | 0.032 | |
| GRB10 | growth factor receptor-bound protein 10 | 0.031 | |
| NOG | noggin | 0.029 | |
| CACNA1G | calcium channel, voltage-dependent, T type, alpha 1G subunit | 0.028 | |
| FGF3 | fibroblast growth factor 3 | 0.027 | |
| MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.025 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.022 | |
| CTGF | connective tissue growth factor | 0.020 | |
| IRS1 | insulin receptor substrate 1 | 0.019 | |
| FGF7 | fibroblast growth factor 7 | 0.019 | |
| WNT3 | wingless-type MMTV integration site family, member 3 | 0.019 | |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.017 | |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.017 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.016 | |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.016 | |
| GHR | growth hormone receptor | 0.016 | |
| LHX3 | LIM homeobox 3 | 0.015 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.014 | |
| TLX1 | T-cell leukemia homeobox 1 | 0.014 | |
| EID1 | EP300 interacting inhibitor of differentiation 1 | 0.014 | |
| GDNF | glial cell derived neurotrophic factor | 0.014 | |
| IHH | Indian hedgehog | 0.014 | |
| CCDC48 | coiled-coil domain containing 48 | 0.013 | |
| TG | thyroglobulin | 0.013 | |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.013 | |
| FGFBP1 | fibroblast growth factor binding protein 1 | 0.011 | |
| SOX21 | SRY (sex determining region Y)-box 21 | 0.011 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.011 | |
| SOX1 | SRY (sex determining region Y)-box 1 | 0.010 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.010 |