IMP
Process View
The network for 'cardiac septum morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
cardiac septum morphogenesis
The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Shh | sonic hedgehog | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Gli3 | GLI-Kruppel family member GLI3 | 1.000 | |
| Pax3 | paired box gene 3 | 0.999 | |
| Pax2 | paired box gene 2 | 0.999 | |
| Tbx3 | T-box 3 | 0.999 | |
| Gata4 | GATA binding protein 4 | 0.998 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.998 | |
| Foxc1 | forkhead box C1 | 0.998 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.998 | |
| Bmp4 | bone morphogenetic protein 4 | 0.998 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.997 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.997 | |
| Nodal | nodal | 0.996 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 0.996 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.992 | |
| Hes1 | hairy and enhancer of split 1 (Drosophila) | 0.991 | |
| Foxc2 | forkhead box C2 | 0.991 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.990 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.989 | |
| Jag1 | jagged 1 | 0.988 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.982 | |
| Meox2 | mesenchyme homeobox 2 | 0.981 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.975 | |
| Tbx1 | T-box 1 | 0.974 | |
| Sox2 | SRY-box containing gene 2 | 0.970 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.970 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.964 | |
| Chrd | chordin | 0.947 | |
| Nog | noggin | 0.941 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.940 | |
| Vegfa | vascular endothelial growth factor A | 0.935 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.935 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.921 | |
| Rarg | retinoic acid receptor, gamma | 0.916 | |
| Tbx2 | T-box 2 | 0.915 | |
| Dll1 | delta-like 1 (Drosophila) | 0.915 | |
| Scn5a | sodium channel, voltage-gated, type V, alpha | 0.915 | |
| Wnt3a | wingless-related MMTV integration site 3A | 0.914 | |
| Prrx1 | paired related homeobox 1 | 0.913 | |
| Rbpj | recombination signal binding protein for immunoglobulin kappa J region | 0.887 | |
| Hoxa1 | homeobox A1 | 0.887 | |
| Dvl2 | dishevelled 2, dsh homolog (Drosophila) | 0.878 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.877 | |
| Sox9 | SRY-box containing gene 9 | 0.866 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.856 | |
| Hspg2 | perlecan (heparan sulfate proteoglycan 2) | 0.842 | |
| Smo | smoothened homolog (Drosophila) | 0.826 | |
| Fgf10 | fibroblast growth factor 10 | 0.821 | |
| Acvr1 | activin A receptor, type 1 | 0.810 | |
| Foxf1a | forkhead box F1a | 0.799 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.791 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.790 | |
| Lhx1 | LIM homeobox protein 1 | 0.782 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.777 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.776 | |
| Mesp1 | mesoderm posterior 1 | 0.772 | |
| Rxra | retinoid X receptor alpha | 0.771 | |
| Emx2 | empty spiracles homolog 2 (Drosophila) | 0.771 | |
| Psen1 | presenilin 1 | 0.764 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.760 | |
| Lrp6 | low density lipoprotein receptor-related protein 6 | 0.675 | |
| Foxg1 | forkhead box G1 | 0.648 | |
| Snai1 | snail homolog 1 (Drosophila) | 0.647 | |
| Pou3f3 | POU domain, class 3, transcription factor 3 | 0.646 | |
| Gata6 | GATA binding protein 6 | 0.638 | |
| Lhx3 | LIM homeobox protein 3 | 0.630 | |
| Sox11 | SRY-box containing gene 11 | 0.591 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.586 | |
| Uncx | UNC homeobox | 0.572 | |
| Rarb | retinoic acid receptor, beta | 0.560 | |
| Gli1 | GLI-Kruppel family member GLI1 | 0.556 | |
| Sox7 | SRY-box containing gene 7 | 0.543 | |
| Prrx2 | paired related homeobox 2 | 0.542 | |
| Axin1 | axin 1 | 0.541 | |
| Dvl1 | dishevelled, dsh homolog 1 (Drosophila) | 0.534 | |
| Ptk7 | PTK7 protein tyrosine kinase 7 | 0.529 | |
| Wnt4 | wingless-related MMTV integration site 4 | 0.522 | |
| Hey1 | hairy/enhancer-of-split related with YRPW motif 1 | 0.521 | |
| En1 | engrailed 1 | 0.518 | |
| Alx4 | aristaless-like homeobox 4 | 0.517 | |
| Notch2 | Notch gene homolog 2 (Drosophila) | 0.513 | |
| Dkk1 | dickkopf homolog 1 (Xenopus laevis) | 0.506 | |
| Fgf18 | fibroblast growth factor 18 | 0.505 | |
| Twist2 | twist homolog 2 (Drosophila) | 0.497 | |
| Foxh1 | forkhead box H1 | 0.482 | |
| Nfatc4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 0.480 | |
| Npr3 | natriuretic peptide receptor 3 | 0.465 | |
| Col13a1 | collagen, type XIII, alpha 1 | 0.461 | |
| Dvl3 | dishevelled 3, dsh homolog (Drosophila) | 0.459 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.457 | |
| Tal1 | T-cell acute lymphocytic leukemia 1 | 0.453 | |
| Hoxa2 | homeobox A2 | 0.434 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.431 | |
| Gpc3 | glypican 3 | 0.419 | |
| Smad3 | MAD homolog 3 (Drosophila) | 0.411 | |
| Wnt5a | wingless-related MMTV integration site 5A | 0.409 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.398 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.388 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| JAG1 | jagged 1 | 0.999 | |
| NOTCH1 | notch 1 | 0.987 | |
| NKX2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.984 | |
| TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.974 | |
| TAL1 | T-cell acute lymphocytic leukemia 1 | 0.952 | |
| NOTCH3 | notch 3 | 0.937 | |
| TBX5 | T-box 5 | 0.866 | |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.791 | |
| BMP2 | bone morphogenetic protein 2 | 0.691 | |
| TGFB1 | transforming growth factor, beta 1 | 0.678 | |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.676 | |
| RUNX1 | runt-related transcription factor 1 | 0.520 | |
| GATA2 | GATA binding protein 2 | 0.514 | |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.476 | |
| SETD8 | SET domain containing (lysine methyltransferase) 8 | 0.444 | |
| RXRA | retinoid X receptor, alpha | 0.383 | |
| GATA4 | GATA binding protein 4 | 0.316 | |
| SMAD7 | SMAD family member 7 | 0.300 | |
| MED25 | mediator complex subunit 25 | 0.260 | |
| SMAD3 | SMAD family member 3 | 0.235 | |
| AXIN1 | axin 1 | 0.234 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.199 | |
| DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.173 | |
| ACVR1 | activin A receptor, type I | 0.163 | |
| GSK3B | glycogen synthase kinase 3 beta | 0.160 | |
| MYOD1 | myogenic differentiation 1 | 0.131 | |
| CTBP2 | C-terminal binding protein 2 | 0.123 | |
| CSNK1E | casein kinase 1, epsilon | 0.119 | |
| ILK | integrin-linked kinase | 0.114 | |
| FGF10 | fibroblast growth factor 10 | 0.103 | |
| EP300 | E1A binding protein p300 | 0.095 | |
| DLL1 | delta-like 1 (Drosophila) | 0.094 | |
| WNT3A | wingless-type MMTV integration site family, member 3A | 0.094 | |
| MAPK8 | mitogen-activated protein kinase 8 | 0.093 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.090 | |
| CXXC5 | CXXC finger protein 5 | 0.080 | |
| SMAD6 | SMAD family member 6 | 0.078 | |
| FSTL1 | follistatin-like 1 | 0.073 | |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.073 | |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.069 | |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.063 | |
| GDF5 | growth differentiation factor 5 | 0.058 | |
| GATA1 | GATA binding protein 1 (globin transcription factor 1) | 0.057 | |
| NOTCH2 | notch 2 | 0.054 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.054 | |
| SMAD9 | SMAD family member 9 | 0.053 | |
| LRRK2 | leucine-rich repeat kinase 2 | 0.048 | |
| CREBBP | CREB binding protein | 0.047 | |
| TGFB3 | transforming growth factor, beta 3 | 0.045 | |
| CTGF | connective tissue growth factor | 0.043 | |
| SKIL | SKI-like oncogene | 0.042 | |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.042 | |
| MSX1 | msh homeobox 1 | 0.041 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.041 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.040 | |
| ENG | endoglin | 0.038 | |
| PAX8 | paired box 8 | 0.038 | |
| ZFPM1 | zinc finger protein, multitype 1 | 0.033 | |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.033 | |
| HOXD12 | homeobox D12 | 0.032 | |
| SIRT1 | sirtuin 1 | 0.031 | |
| MAML1 | mastermind-like 1 (Drosophila) | 0.030 | |
| MARCKSL1 | MARCKS-like 1 | 0.029 | |
| SOX7 | SRY (sex determining region Y)-box 7 | 0.027 | |
| JAG2 | jagged 2 | 0.027 | |
| WT1 | Wilms tumor 1 | 0.025 | |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.025 | |
| NRP1 | neuropilin 1 | 0.024 | |
| SMAD1 | SMAD family member 1 | 0.024 | |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.022 | |
| ZNF512B | zinc finger protein 512B | 0.021 | |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) | 0.021 | |
| FZD1 | frizzled homolog 1 (Drosophila) | 0.020 | |
| BMP4 | bone morphogenetic protein 4 | 0.020 | |
| PDGFC | platelet derived growth factor C | 0.019 | |
| TCF12 | transcription factor 12 | 0.019 | |
| POU4F2 | POU class 4 homeobox 2 | 0.018 | |
| SOX13 | SRY (sex determining region Y)-box 13 | 0.018 | |
| DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.017 | |
| MAFA | v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) | 0.017 | |
| HIC1 | hypermethylated in cancer 1 | 0.016 | |
| FERMT2 | fermitin family member 2 | 0.016 | |
| HEYL | hairy/enhancer-of-split related with YRPW motif-like | 0.015 | |
| SOX18 | SRY (sex determining region Y)-box 18 | 0.015 | |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) | 0.015 | |
| VEGFA | vascular endothelial growth factor A | 0.015 | |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.015 | |
| GATA3 | GATA binding protein 3 | 0.015 | |
| FOXF2 | forkhead box F2 | 0.014 | |
| FZD7 | frizzled homolog 7 (Drosophila) | 0.013 | |
| ACVR1B | activin A receptor, type IB | 0.013 | |
| FGF3 | fibroblast growth factor 3 | 0.012 | |
| PIAS4 | protein inhibitor of activated STAT, 4 | 0.012 | |
| NR5A1 | nuclear receptor subfamily 5, group A, member 1 | 0.012 | |
| EFNB2 | ephrin-B2 | 0.012 | |
| GATA5 | GATA binding protein 5 | 0.012 | |
| TBX2 | T-box 2 | 0.011 | |
| FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.011 | |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.011 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.011 |