The network for 'embryonic camera type eye development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic camera type eye development

The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.

Mus musculus
Name Description Probability Func Analog Organism
Shh sonic hedgehog 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Fgfr2 fibroblast growth factor receptor 2 0.997
Hand1 heart and neural crest derivatives expressed transcript 1 0.996
Pax3 paired box gene 3 0.996
Bmp4 bone morphogenetic protein 4 0.996
Pitx2 paired-like homeodomain transcription factor 2 0.995
Prrx1 paired related homeobox 1 0.994
Tbx1 T-box 1 0.992
Tbx3 T-box 3 0.992
Bmp7 bone morphogenetic protein 7 0.990
Hand2 heart and neural crest derivatives expressed transcript 2 0.990
Foxc1 forkhead box C1 0.986
Pax2 paired box gene 2 0.983
Fgf8 fibroblast growth factor 8 0.982
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.978
Msx1 homeobox, msh-like 1 0.978
Rarb retinoic acid receptor, beta 0.973
Otx2 orthodenticle homolog 2 (Drosophila) 0.965
Rarg retinoic acid receptor, gamma 0.958
Eya1 eyes absent 1 homolog (Drosophila) 0.951
Tcfap2a transcription factor AP-2, alpha 0.949
Runx2 runt related transcription factor 2 0.942
Sox2 SRY-box containing gene 2 0.938
Foxc2 forkhead box C2 0.931
Msx2 homeobox, msh-like 2 0.917
Fgfr1 fibroblast growth factor receptor 1 0.910
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.903
Zeb1 zinc finger E-box binding homeobox 1 0.862
Pitx1 paired-like homeodomain transcription factor 1 0.838
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.815
Tgfb2 transforming growth factor, beta 2 0.785
Wnt5a wingless-related MMTV integration site 5A 0.783
Pax6 paired box gene 6 0.748
Pbx1 pre B-cell leukemia transcription factor 1 0.741
Gli2 GLI-Kruppel family member GLI2 0.729
Sox11 SRY-box containing gene 11 0.703
Gsc goosecoid homeobox 0.703
Prrx2 paired related homeobox 2 0.700
Tbx15 T-box 15 0.694
Lhx1 LIM homeobox protein 1 0.665
Nog noggin 0.646
Hoxa13 homeobox A13 0.643
Smo smoothened homolog (Drosophila) 0.642
Smad6 MAD homolog 6 (Drosophila) 0.633
Gbx2 gastrulation brain homeobox 2 0.626
Gas1 growth arrest specific 1 0.619
Acvr1 activin A receptor, type 1 0.597
Nodal nodal 0.588
Pax8 paired box gene 8 0.587
Dlx5 distal-less homeobox 5 0.566
Vangl2 vang-like 2 (van gogh, Drosophila) 0.555
Hoxa1 homeobox A1 0.544
Bmp5 bone morphogenetic protein 5 0.543
Fgf10 fibroblast growth factor 10 0.542
Lrp6 low density lipoprotein receptor-related protein 6 0.528
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.482
Pou5f1 POU domain, class 5, transcription factor 1 0.468
Col2a1 collagen, type II, alpha 1 0.465
Isl1 ISL1 transcription factor, LIM/homeodomain 0.465
Drd2 dopamine receptor D2 0.455
Alx4 aristaless-like homeobox 4 0.447
Zic3 zinc finger protein of the cerebellum 3 0.439
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.412
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.395
Chrd chordin 0.389
Jag1 jagged 1 0.385
Gpc3 glypican 3 0.383
Lrp2 low density lipoprotein receptor-related protein 2 0.366
Chd7 chromodomain helicase DNA binding protein 7 0.358
Foxh1 forkhead box H1 0.353
Gdf5 growth differentiation factor 5 0.352
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 0.342
Tcf21 transcription factor 21 0.335
Wnt3a wingless-related MMTV integration site 3A 0.332
Rnf2 ring finger protein 2 0.327
Twist2 twist homolog 2 (Drosophila) 0.326
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.313
Ptk7 PTK7 protein tyrosine kinase 7 0.307
Ret ret proto-oncogene 0.285
Hoxa11 homeobox A11 0.284
Fzd8 frizzled homolog 8 (Drosophila) 0.284
Efna2 ephrin A2 0.282
Sall4 sal-like 4 (Drosophila) 0.272
Gata4 GATA binding protein 4 0.256
Dok1 docking protein 1 0.254
Ntf3 neurotrophin 3 0.240
Hoxd11 homeobox D11 0.236
Gja3 gap junction protein, alpha 3 0.232
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.232
Tcfap2c transcription factor AP-2, gamma 0.226
Bmpr1a bone morphogenetic protein receptor, type 1A 0.225
Ednra endothelin receptor type A 0.215
Hoxb3 homeobox B3 0.208
Grb10 growth factor receptor bound protein 10 0.208
Pou3f3 POU domain, class 3, transcription factor 3 0.204
Alx3 aristaless-like homeobox 3 0.199
Bmp2 bone morphogenetic protein 2 0.197
Ece1 endothelin converting enzyme 1 0.193
Tcf7l1 transcription factor 7-like 1 (T-cell specific, HMG box) 0.193
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
tbx1 T-box 1 0.996
tfap2a transcription factor AP-2 alpha 0.976
gli1 GLI-Kruppel family member 1 0.974
otx2 orthodenticle homolog 2 0.972
bmp2b bone morphogenetic protein 2b 0.971
lhx2b LIM homeobox 2b 0.970
sox2 SRY-box containing gene 2 0.964
shha sonic hedgehog a 0.951
rx3 retinal homeobox gene 3 0.936
fgf3 fibroblast growth factor 3 0.934
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.931
ndr2 nodal-related 2 0.893
fgf17 fibroblast growth factor 17 0.886
gbx2 gastrulation brain homeo box 2 0.884
zic2a zic family member 2 (odd-paired homolog, Drosophila), a 0.861
dlx2a distal-less homeobox gene 2a 0.861
bmp4 bone morphogenetic protein 4 0.851
cdh2 cadherin 2, neuronal 0.845
wnt5b wingless-type MMTV integration site family, member 5b 0.841
wnt3 wingless-type MMTV integration site family, member 3 0.835
eya1 eyes absent homolog 1 0.827
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.819
foxa2 forkhead box A2 0.817
barhl2 BarH-like 2 0.759
mab21l2 mab-21-like 2 0.730
eng2a engrailed 2a 0.716
rarga retinoic acid receptor gamma a 0.699
bmp2a bone morphogenetic protein 2a 0.689
wnt2 wingless-type MMTV integration site family member 2 0.688
fezf2 FEZ family zinc finger 2 0.681
isl1 islet1 0.668
chd chordin 0.664
wnt11 wingless-type MMTV integration site family, member 11 0.651
wnt10a wingless-type MMTV integration site family, member 10a 0.641
irx1a iroquois homeobox protein 1, a 0.630
flh floating head 0.625
znf503 zinc finger protein 503 0.621
pax2a paired box gene 2a 0.602
wnt3a wingless-type MMTV integration site family, member 3A 0.582
foxn4 forkhead box N4 0.551
hnf1ba HNF1 homeobox Ba 0.511
dkk1b dickkopf 1b 0.508
fgf8b fibroblast growth factor 8 b 0.502
fgf10a fibroblast growth factor 10a 0.502
fgf8a fibroblast growth factor 8 a 0.495
sox32 SRY-box containing gene 32 0.486
dlx4a distal-less homeobox gene 4a 0.460
six3b sine oculis homeobox homolog 3b 0.452
gli2a GLI-Kruppel family member GLI2a 0.449
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.403
notch2 notch homolog 2 0.400
spry2 sprouty homolog 2 0.395
ascl1a achaete-scute complex-like 1a (Drosophila) 0.392
atoh7 atonal homolog 7 0.376
dharma dharma 0.368
foxd3 forkhead box D3 0.360
zic3 zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila) 0.358
nrxn2a neurexin 2a 0.342
vsx1 visual system homeobox 1 homolog, chx10-like 0.342
sfrp1a secreted frizzled-related protein 1a 0.330
ptch1 patched 1 0.327
lhx6 LIM homeobox 6 0.327
vax1 ventral anterior homeobox 1 0.316
map2k4a mitogen-activated protein kinase kinase 4a 0.311
rest RE1-silencing transcription factor 0.301
vax2 ventral anterior homeobox 2 0.300
wnt8b wingless-type MMTV integration site family, member 8b 0.299
ephb3a eph receptor B3a 0.299
fgfr1b fibroblast growth factor receptor 1b 0.299
tcf7 transcription factor 7 (T-cell specific, HMG-box) 0.295
osr1 odd-skipped related 1 (Drosophila) 0.283
nkx3.2 NK3 homeobox 2 0.273
lox lysyl oxidase 0.273
fzd5 frizzled homolog 5 0.270
pax6b paired box gene 6b 0.269
six2a sine oculis-related homeobox 2a 0.268
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.266
dlx4b distal-less homeobox gene 4b 0.265
runx3 runt-related transcription factor 3 0.262
nkx1.2la NK1 transcription factor related 2-like,a 0.258
tgfb2 transforming growth factor, beta 2 0.255
hmgcrb 3-hydroxy-3-methylglutaryl-Coenzyme A reductase b 0.254
fzd7a frizzled homolog 7a 0.250
pitx3 paired-like homeodomain transcription factor 3 0.247
tbx16 T-box gene 16 0.243
spry1 sprouty homolog 1 (Drosophila) 0.238
foxc1a forkhead box C1a 0.237
lhx1b LIM homeobox 1b 0.235
rx2 retinal homeobox gene 2 0.230
gbx1 gastrulation brain homeobox 1 0.229
hmx4 H6 family homeobox 4 0.228
foxp2 forkhead box P2 0.225
fgf20a fibroblast growth factor 20a 0.221
lamb1a laminin, beta 1a 0.219
msxe muscle segment homeobox E 0.218
foxg1a forkhead box G1a 0.214
fgf4 fibroblast growth factor 4 0.214
her5 hairy-related 5 0.210
foxd5 forkhead box D5 0.202
hmx3 homeo box (H6 family) 3 0.201
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
EP300 E1A binding protein p300 1.000
MED25 mediator complex subunit 25 1.000
CREBBP CREB binding protein 0.999
UBE2I ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) 0.993
RUNX1 runt-related transcription factor 1 0.982
HNF4A hepatocyte nuclear factor 4, alpha 0.963
RXRA retinoid X receptor, alpha 0.960
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.957
SETD8 SET domain containing (lysine methyltransferase) 8 0.947
NCOA1 nuclear receptor coactivator 1 0.880
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor 0.844
BCOR BCL6 corepressor 0.824
HIPK2 homeodomain interacting protein kinase 2 0.718
SP1 Sp1 transcription factor 0.655
MAFA v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) 0.649
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.565
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 0.552
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.550
PTCH1 patched 1 0.524
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.514
INSR insulin receptor 0.514
MMP14 matrix metallopeptidase 14 (membrane-inserted) 0.463
MECP2 methyl CpG binding protein 2 (Rett syndrome) 0.451
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 0.446
ARID2 AT rich interactive domain 2 (ARID, RFX-like) 0.433
FGFR1 fibroblast growth factor receptor 1 0.412
PML promyelocytic leukemia 0.412
ARID1B AT rich interactive domain 1B (SWI1-like) 0.391
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.378
NCOA3 nuclear receptor coactivator 3 0.366
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.366
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.355
WNT3A wingless-type MMTV integration site family, member 3A 0.355
DKK1 dickkopf homolog 1 (Xenopus laevis) 0.351
SMARCD1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1 0.348
GATA2 GATA binding protein 2 0.338
NR0B2 nuclear receptor subfamily 0, group B, member 2 0.311
IRS1 insulin receptor substrate 1 0.307
CAT catalase 0.297
GSK3B glycogen synthase kinase 3 beta 0.283
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 0.280
DCAF7 DDB1 and CUL4 associated factor 7 0.280
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.278
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.273
GRB10 growth factor receptor-bound protein 10 0.269
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.225
PIAS2 protein inhibitor of activated STAT, 2 0.197
MYOD1 myogenic differentiation 1 0.194
NCOR1 nuclear receptor corepressor 1 0.192
HOXD12 homeobox D12 0.191
CAV1 caveolin 1, caveolae protein, 22kDa 0.178
SMAD4 SMAD family member 4 0.174
KCTD1 potassium channel tetramerisation domain containing 1 0.173
NOG noggin 0.168
GAB1 GRB2-associated binding protein 1 0.162
NEUROD1 neurogenic differentiation 1 0.162
SKI v-ski sarcoma viral oncogene homolog (avian) 0.157
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.147
COL2A1 collagen, type II, alpha 1 0.146
LHX2 LIM homeobox 2 0.143
HIC1 hypermethylated in cancer 1 0.142
TCF12 transcription factor 12 0.138
MPZL1 myelin protein zero-like 1 0.137
NCOR2 nuclear receptor corepressor 2 0.135
BBS1 Bardet-Biedl syndrome 1 0.133
SH3BP4 SH3-domain binding protein 4 0.132
FOXC1 forkhead box C1 0.132
LRRK2 leucine-rich repeat kinase 2 0.128
PDX1 pancreatic and duodenal homeobox 1 0.122
PPARA peroxisome proliferator-activated receptor alpha 0.118
RXRB retinoid X receptor, beta 0.113
GABPA GA binding protein transcription factor, alpha subunit 60kDa 0.113
NKX2-2 NK2 homeobox 2 0.112
PIAS1 protein inhibitor of activated STAT, 1 0.111
POU3F2 POU class 3 homeobox 2 0.110
STAT5A signal transducer and activator of transcription 5A 0.101
TCF4 transcription factor 4 0.099
FOXF1 forkhead box F1 0.099
FOXG1 forkhead box G1 0.098
KAT2B K(lysine) acetyltransferase 2B 0.098
POU4F2 POU class 4 homeobox 2 0.097
LRRN2 leucine rich repeat neuronal 2 0.093
GAB2 GRB2-associated binding protein 2 0.092
FZD10 frizzled homolog 10 (Drosophila) 0.089
KANK2 KN motif and ankyrin repeat domains 2 0.088
MNX1 motor neuron and pancreas homeobox 1 0.083
SKIL SKI-like oncogene 0.083
LMO2 LIM domain only 2 (rhombotin-like 1) 0.082
SIX3 SIX homeobox 3 0.081
SETD7 SET domain containing (lysine methyltransferase) 7 0.080
SMAD3 SMAD family member 3 0.080
SIRT1 sirtuin 1 0.079
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.077
PHOX2A paired-like homeobox 2a 0.077
SPOP speckle-type POZ protein 0.077
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.075
POU4F1 POU class 4 homeobox 1 0.074
ZIC1 Zic family member 1 (odd-paired homolog, Drosophila) 0.074
SOX1 SRY (sex determining region Y)-box 1 0.073
HOXD13 homeobox D13 0.073
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism