Process View
The network for 'regulation of cardiac chamber morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
Pitx2 | paired-like homeodomain transcription factor 2 | 0.999 | |
Fgfr2 | fibroblast growth factor receptor 2 | 0.999 | |
Tbx3 | T-box 3 | 0.999 | |
Shh | sonic hedgehog | 0.996 | |
Hoxa1 | homeobox A1 | 0.994 | |
Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.989 | |
Tcfap2a | transcription factor AP-2, alpha | 0.988 | |
Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.984 | |
Jag1 | jagged 1 | 0.974 | |
Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.970 | |
Foxg1 | forkhead box G1 | 0.969 | |
Fgf8 | fibroblast growth factor 8 | 0.956 | |
Bmp4 | bone morphogenetic protein 4 | 0.949 | |
Pax3 | paired box gene 3 | 0.948 | |
Hcn4 | hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | 0.947 | |
Pax2 | paired box gene 2 | 0.939 | |
Pitx1 | paired-like homeodomain transcription factor 1 | 0.938 | |
Eya1 | eyes absent 1 homolog (Drosophila) | 0.938 | |
Chd7 | chromodomain helicase DNA binding protein 7 | 0.921 | |
Foxc2 | forkhead box C2 | 0.907 | |
Tbx1 | T-box 1 | 0.837 | |
Fgfr1 | fibroblast growth factor receptor 1 | 0.814 | |
Otx2 | orthodenticle homolog 2 (Drosophila) | 0.755 | |
Lrp6 | low density lipoprotein receptor-related protein 6 | 0.736 | |
Zeb1 | zinc finger E-box binding homeobox 1 | 0.661 | |
Foxc1 | forkhead box C1 | 0.659 | |
Fgf10 | fibroblast growth factor 10 | 0.656 | |
Gli3 | GLI-Kruppel family member GLI3 | 0.656 | |
Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.647 | |
Chrd | chordin | 0.637 | |
Wnt3a | wingless-related MMTV integration site 3A | 0.634 | |
Gbx2 | gastrulation brain homeobox 2 | 0.633 | |
Scn5a | sodium channel, voltage-gated, type V, alpha | 0.632 | |
Sall4 | sal-like 4 (Drosophila) | 0.611 | |
Msx1 | homeobox, msh-like 1 | 0.604 | |
Sox2 | SRY-box containing gene 2 | 0.598 | |
Vegfa | vascular endothelial growth factor A | 0.561 | |
Rarg | retinoic acid receptor, gamma | 0.547 | |
Efnb2 | ephrin B2 | 0.543 | |
Dlx5 | distal-less homeobox 5 | 0.543 | |
Rxra | retinoid X receptor alpha | 0.539 | |
Prrx1 | paired related homeobox 1 | 0.535 | |
Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.524 | |
T | brachyury | 0.499 | |
Lef1 | lymphoid enhancer binding factor 1 | 0.447 | |
Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.436 | |
Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.412 | |
Gsc | goosecoid homeobox | 0.406 | |
Lrp5 | low density lipoprotein receptor-related protein 5 | 0.400 | |
Smad6 | MAD homolog 6 (Drosophila) | 0.394 | |
Tbx5 | T-box 5 | 0.370 | |
Lmx1a | LIM homeobox transcription factor 1 alpha | 0.366 | |
Tbx4 | T-box 4 | 0.322 | |
Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.284 | |
Zic3 | zinc finger protein of the cerebellum 3 | 0.265 | |
Gata3 | GATA binding protein 3 | 0.253 | |
Gja5 | gap junction protein, alpha 5 | 0.226 | |
Ece1 | endothelin converting enzyme 1 | 0.223 | |
Bmp5 | bone morphogenetic protein 5 | 0.188 | |
Pax9 | paired box gene 9 | 0.186 | |
Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.185 | |
Rarb | retinoic acid receptor, beta | 0.184 | |
Wt1 | Wilms tumor 1 homolog | 0.178 | |
Smo | smoothened homolog (Drosophila) | 0.171 | |
Ighmbp2 | immunoglobulin mu binding protein 2 | 0.168 | |
Meox2 | mesenchyme homeobox 2 | 0.166 | |
Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.163 | |
Fgf3 | fibroblast growth factor 3 | 0.162 | |
Gata4 | GATA binding protein 4 | 0.159 | |
Hmx3 | H6 homeobox 3 | 0.152 | |
Tcf21 | transcription factor 21 | 0.151 | |
Otx1 | orthodenticle homolog 1 (Drosophila) | 0.150 | |
Fgfr3 | fibroblast growth factor receptor 3 | 0.148 | |
Pou5f1 | POU domain, class 5, transcription factor 1 | 0.143 | |
Nos3 | nitric oxide synthase 3, endothelial cell | 0.143 | |
Nodal | nodal | 0.141 | |
Nanog | Nanog homeobox | 0.138 | |
Foxh1 | forkhead box H1 | 0.135 | |
Hoxa3 | homeobox A3 | 0.133 | |
Trp63 | transformation related protein 63 | 0.126 | |
Alx1 | ALX homeobox 1 | 0.126 | |
Hoxa13 | homeobox A13 | 0.124 | |
Apc | adenomatosis polyposis coli | 0.121 | |
Axin1 | axin 1 | 0.114 | |
Egfr | epidermal growth factor receptor | 0.110 | |
Hoxa2 | homeobox A2 | 0.108 | |
Gata6 | GATA binding protein 6 | 0.108 | |
Msx2 | homeobox, msh-like 2 | 0.104 | |
Emx2 | empty spiracles homolog 2 (Drosophila) | 0.104 | |
Myl2 | myosin, light polypeptide 2, regulatory, cardiac, slow | 0.102 | |
Myo6 | myosin VI | 0.102 | |
Myf5 | myogenic factor 5 | 0.096 | |
Prrx2 | paired related homeobox 2 | 0.096 | |
Sox9 | SRY-box containing gene 9 | 0.094 | |
Ptk7 | PTK7 protein tyrosine kinase 7 | 0.093 | |
Bdnf | brain derived neurotrophic factor | 0.093 | |
Sox11 | SRY-box containing gene 11 | 0.092 | |
Tgfb2 | transforming growth factor, beta 2 | 0.091 | |
Bmp7 | bone morphogenetic protein 7 | 0.090 | |
Notch2 | Notch gene homolog 2 (Drosophila) | 0.089 |
Name | Description | Probability | Func Analog Organism |
---|---|---|---|
foxa1 | forkhead box A1 | 0.730 | |
nkx3.2 | NK3 homeobox 2 | 0.727 | |
foxi1 | forkhead box I1 | 0.714 | |
nkx2.2b | NK2 transcription factor related 2b | 0.436 | |
hhex | hematopoietically expressed homeobox | 0.349 | |
dbx1a | developing brain homeobox 1a | 0.280 | |
foxa2 | forkhead box A2 | 0.259 | |
hoxa2b | homeo box A2b | 0.227 | |
nkx2.1a | NK2 homeobox 1a | 0.216 | |
nkx2.9 | NK2 transcription factor related, locus 9 (Drosophila) | 0.153 | |
hand2 | heart and neural crest derivatives expressed transcript 2 | 0.147 | |
dbx1b | developing brain homeobox 1b | 0.143 | |
pax2a | paired box gene 2a | 0.105 | |
tbx20 | T-box 20 | 0.076 | |
lft2 | lefty2 | 0.057 | |
gata4 | GATA-binding protein 4 | 0.056 | |
ncs1a | neuronal calcium sensor 1a | 0.056 | |
olig3 | oligodendrocyte transcription factor 3 | 0.055 | |
lhx1b | LIM homeobox 1b | 0.055 | |
six3b | sine oculis homeobox homolog 3b | 0.052 | |
otx1a | orthodenticle homolog 1a | 0.050 | |
tcf21 | transcription factor 21 | 0.047 | |
hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.045 | |
cmlc1 | cardiac myosin light chain-1 | 0.044 | |
hoxb2a | homeo box B2a | 0.043 | |
hoxa9a | homeo box A9a | 0.042 | |
nkx2.1b | NK2 homeobox 1b | 0.041 | |
lhx5 | LIM homeobox 5 | 0.039 | |
fzd8b | frizzled homolog 8b | 0.038 | |
hoxa3a | homeo box A3a | 0.032 | |
hoxd10a | homeo box D10a | 0.030 | |
hbbe3 | hemoglobin beta embryonic-3 | 0.027 | |
myh6 | myosin, heavy polypeptide 6, cardiac muscle, alpha | 0.027 | |
spaw | southpaw | 0.026 | |
tbx5b | T-box 5b | 0.026 | |
gata6 | GATA-binding protein 6 | 0.026 | |
ascl1b | achaete-scute complex-like 1b (Drosophila) | 0.026 | |
pcdh8 | protocadherin 8 | 0.024 | |
zic6 | zic family member 6 | 0.022 | |
npnt | nephronectin | 0.022 | |
ihha | Indian hedgehog homolog a | 0.022 | |
satb2 | SATB homeobox 2 | 0.022 | |
tbx5a | T-box 5a | 0.020 | |
si:ch211-285f17.1 | si:ch211-285f17.1 | 0.020 | |
pdgfaa | platelet-derived growth factor alpha a | 0.019 | |
ascl1a | achaete-scute complex-like 1a (Drosophila) | 0.019 | |
her5 | hairy-related 5 | 0.018 | |
pdgfab | platelet derived growth factor alpha b | 0.018 | |
hoxc1a | homeo box C1a | 0.017 | |
tnnc1a | troponin C type 1a (slow) | 0.017 | |
pnx | posterior neuron-specific homeobox | 0.016 | |
emx3 | empty spiracles homeobox 3 | 0.016 | |
rx3 | retinal homeobox gene 3 | 0.016 | |
meis3 | myeloid ecotropic viral integration site 3 | 0.016 | |
gata5 | GATA-binding protein 5 | 0.016 | |
nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.016 | |
lft1 | lefty1 | 0.015 | |
chrna2a | cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) | 0.015 | |
flt4 | fms-related tyrosine kinase 4 | 0.015 | |
hoxc4a | homeo box C4a | 0.015 | |
hapln1a | hyaluronan and proteoglycan link protein 1a | 0.015 | |
hoxb5b | homeo box B5b | 0.015 | |
hoxb8b | homeo box B8b | 0.015 | |
six4b | sine oculis homeobox homolog 4b | 0.014 | |
nkx2.3 | NK2 transcription factor related 3 | 0.014 | |
cyp26c1 | cytochrome P450, family 26, subfamily C, polypeptide 1 | 0.014 | |
slc6a6 | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 0.014 | |
vsx2 | visual system homeobox 2 | 0.014 | |
slc8a1a | solute carrier family 8 (sodium/calcium exchanger), member 1a | 0.013 | |
zgc:100838 | zgc:100838 | 0.012 | |
six4a | sine oculis homeobox homolog 4a | 0.011 | |
znfl2a | zinc finger-like gene 2a | 0.011 | |
bmpr1ba | bone morphogenetic protein receptor, type 1ba | 0.011 | |
drl | draculin | 0.011 | |
barhl2 | BarH-like 2 | 0.011 | |
dkk1b | dickkopf 1b | 0.011 | |
arx | aristaless related homeobox | 0.010 | |
irx4b | iroquois homeobox protein 4b | 0.010 | |
jag1b | jagged 1b | 0.010 | |
msgn1 | mesogenin 1 | 0.010 | |
atp2a2a | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a | 0.010 | |
pax5 | paired box gene 5 | 0.010 |