The network for 'regulation of cardiac chamber morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cardiac chamber morphogenesis

Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.

Name Description Probability Func Analog Organism
Pitx2 paired-like homeodomain transcription factor 2 0.999
Fgfr2 fibroblast growth factor receptor 2 0.999
Tbx3 T-box 3 0.999
Shh sonic hedgehog 0.996
Hoxa1 homeobox A1 0.994
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.989
Tcfap2a transcription factor AP-2, alpha 0.988
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.984
Jag1 jagged 1 0.974
Vangl2 vang-like 2 (van gogh, Drosophila) 0.970
Foxg1 forkhead box G1 0.969
Fgf8 fibroblast growth factor 8 0.956
Bmp4 bone morphogenetic protein 4 0.949
Pax3 paired box gene 3 0.948
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 0.947
Pax2 paired box gene 2 0.939
Pitx1 paired-like homeodomain transcription factor 1 0.938
Eya1 eyes absent 1 homolog (Drosophila) 0.938
Chd7 chromodomain helicase DNA binding protein 7 0.921
Foxc2 forkhead box C2 0.907
Tbx1 T-box 1 0.837
Fgfr1 fibroblast growth factor receptor 1 0.814
Otx2 orthodenticle homolog 2 (Drosophila) 0.755
Lrp6 low density lipoprotein receptor-related protein 6 0.736
Zeb1 zinc finger E-box binding homeobox 1 0.661
Foxc1 forkhead box C1 0.659
Fgf10 fibroblast growth factor 10 0.656
Gli3 GLI-Kruppel family member GLI3 0.656
Hand2 heart and neural crest derivatives expressed transcript 2 0.647
Chrd chordin 0.637
Wnt3a wingless-related MMTV integration site 3A 0.634
Gbx2 gastrulation brain homeobox 2 0.633
Scn5a sodium channel, voltage-gated, type V, alpha 0.632
Sall4 sal-like 4 (Drosophila) 0.611
Msx1 homeobox, msh-like 1 0.604
Sox2 SRY-box containing gene 2 0.598
Vegfa vascular endothelial growth factor A 0.561
Rarg retinoic acid receptor, gamma 0.547
Efnb2 ephrin B2 0.543
Dlx5 distal-less homeobox 5 0.543
Rxra retinoid X receptor alpha 0.539
Prrx1 paired related homeobox 1 0.535
Six4 sine oculis-related homeobox 4 homolog (Drosophila) 0.524
T brachyury 0.499
Lef1 lymphoid enhancer binding factor 1 0.447
Hand1 heart and neural crest derivatives expressed transcript 1 0.436
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 0.412
Gsc goosecoid homeobox 0.406
Lrp5 low density lipoprotein receptor-related protein 5 0.400
Smad6 MAD homolog 6 (Drosophila) 0.394
Tbx5 T-box 5 0.370
Lmx1a LIM homeobox transcription factor 1 alpha 0.366
Tbx4 T-box 4 0.322
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.284
Zic3 zinc finger protein of the cerebellum 3 0.265
Gata3 GATA binding protein 3 0.253
Gja5 gap junction protein, alpha 5 0.226
Ece1 endothelin converting enzyme 1 0.223
Bmp5 bone morphogenetic protein 5 0.188
Pax9 paired box gene 9 0.186
Ctnnb1 catenin (cadherin associated protein), beta 1 0.185
Rarb retinoic acid receptor, beta 0.184
Wt1 Wilms tumor 1 homolog 0.178
Smo smoothened homolog (Drosophila) 0.171
Ighmbp2 immunoglobulin mu binding protein 2 0.168
Meox2 mesenchyme homeobox 2 0.166
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.163
Fgf3 fibroblast growth factor 3 0.162
Gata4 GATA binding protein 4 0.159
Hmx3 H6 homeobox 3 0.152
Tcf21 transcription factor 21 0.151
Otx1 orthodenticle homolog 1 (Drosophila) 0.150
Fgfr3 fibroblast growth factor receptor 3 0.148
Pou5f1 POU domain, class 5, transcription factor 1 0.143
Nos3 nitric oxide synthase 3, endothelial cell 0.143
Nodal nodal 0.141
Nanog Nanog homeobox 0.138
Foxh1 forkhead box H1 0.135
Hoxa3 homeobox A3 0.133
Trp63 transformation related protein 63 0.126
Alx1 ALX homeobox 1 0.126
Hoxa13 homeobox A13 0.124
Apc adenomatosis polyposis coli 0.121
Axin1 axin 1 0.114
Egfr epidermal growth factor receptor 0.110
Hoxa2 homeobox A2 0.108
Gata6 GATA binding protein 6 0.108
Msx2 homeobox, msh-like 2 0.104
Emx2 empty spiracles homolog 2 (Drosophila) 0.104
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.102
Myo6 myosin VI 0.102
Myf5 myogenic factor 5 0.096
Prrx2 paired related homeobox 2 0.096
Sox9 SRY-box containing gene 9 0.094
Ptk7 PTK7 protein tyrosine kinase 7 0.093
Bdnf brain derived neurotrophic factor 0.093
Sox11 SRY-box containing gene 11 0.092
Tgfb2 transforming growth factor, beta 2 0.091
Bmp7 bone morphogenetic protein 7 0.090
Notch2 Notch gene homolog 2 (Drosophila) 0.089
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
foxa1 forkhead box A1 0.730
nkx3.2 NK3 homeobox 2 0.727
foxi1 forkhead box I1 0.714
nkx2.2b NK2 transcription factor related 2b 0.436
hhex hematopoietically expressed homeobox 0.349
dbx1a developing brain homeobox 1a 0.280
foxa2 forkhead box A2 0.259
hoxa2b homeo box A2b 0.227
nkx2.1a NK2 homeobox 1a 0.216
nkx2.9 NK2 transcription factor related, locus 9 (Drosophila) 0.153
hand2 heart and neural crest derivatives expressed transcript 2 0.147
dbx1b developing brain homeobox 1b 0.143
pax2a paired box gene 2a 0.105
tbx20 T-box 20 0.076
lft2 lefty2 0.057
gata4 GATA-binding protein 4 0.056
ncs1a neuronal calcium sensor 1a 0.056
olig3 oligodendrocyte transcription factor 3 0.055
lhx1b LIM homeobox 1b 0.055
six3b sine oculis homeobox homolog 3b 0.052
otx1a orthodenticle homolog 1a 0.050
tcf21 transcription factor 21 0.047
hey2 hairy/enhancer-of-split related with YRPW motif 2 0.045
cmlc1 cardiac myosin light chain-1 0.044
hoxb2a homeo box B2a 0.043
hoxa9a homeo box A9a 0.042
nkx2.1b NK2 homeobox 1b 0.041
lhx5 LIM homeobox 5 0.039
fzd8b frizzled homolog 8b 0.038
hoxa3a homeo box A3a 0.032
hoxd10a homeo box D10a 0.030
hbbe3 hemoglobin beta embryonic-3 0.027
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.027
spaw southpaw 0.026
tbx5b T-box 5b 0.026
gata6 GATA-binding protein 6 0.026
ascl1b achaete-scute complex-like 1b (Drosophila) 0.026
pcdh8 protocadherin 8 0.024
zic6 zic family member 6 0.022
npnt nephronectin 0.022
ihha Indian hedgehog homolog a 0.022
satb2 SATB homeobox 2 0.022
tbx5a T-box 5a 0.020
si:ch211-285f17.1 si:ch211-285f17.1 0.020
pdgfaa platelet-derived growth factor alpha a 0.019
ascl1a achaete-scute complex-like 1a (Drosophila) 0.019
her5 hairy-related 5 0.018
pdgfab platelet derived growth factor alpha b 0.018
hoxc1a homeo box C1a 0.017
tnnc1a troponin C type 1a (slow) 0.017
pnx posterior neuron-specific homeobox 0.016
emx3 empty spiracles homeobox 3 0.016
rx3 retinal homeobox gene 3 0.016
meis3 myeloid ecotropic viral integration site 3 0.016
gata5 GATA-binding protein 5 0.016
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.016
lft1 lefty1 0.015
chrna2a cholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal) 0.015
flt4 fms-related tyrosine kinase 4 0.015
hoxc4a homeo box C4a 0.015
hapln1a hyaluronan and proteoglycan link protein 1a 0.015
hoxb5b homeo box B5b 0.015
hoxb8b homeo box B8b 0.015
six4b sine oculis homeobox homolog 4b 0.014
nkx2.3 NK2 transcription factor related 3 0.014
cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 0.014
slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.014
vsx2 visual system homeobox 2 0.014
slc8a1a solute carrier family 8 (sodium/calcium exchanger), member 1a 0.013
zgc:100838 zgc:100838 0.012
six4a sine oculis homeobox homolog 4a 0.011
znfl2a zinc finger-like gene 2a 0.011
bmpr1ba bone morphogenetic protein receptor, type 1ba 0.011
drl draculin 0.011
barhl2 BarH-like 2 0.011
dkk1b dickkopf 1b 0.011
arx aristaless related homeobox 0.010
irx4b iroquois homeobox protein 4b 0.010
jag1b jagged 1b 0.010
msgn1 mesogenin 1 0.010
atp2a2a ATPase, Ca++ transporting, cardiac muscle, slow twitch 2a 0.010
pax5 paired box gene 5 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
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Rattus norvegicus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism