The network for 'response to peptide hormone' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to peptide hormone

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.

Mus musculus
Name Description Probability Func Analog Organism
Lepr leptin receptor 1.000
Insr insulin receptor 1.000
Nos3 nitric oxide synthase 3, endothelial cell 0.998
Nos1 nitric oxide synthase 1, neuronal 0.998
Lep leptin 0.998
Ctnnb1 catenin (cadherin associated protein), beta 1 0.997
Pten phosphatase and tensin homolog 0.995
Cav1 caveolin 1, caveolae protein 0.995
Ghr growth hormone receptor 0.994
Ar androgen receptor 0.993
Esr1 estrogen receptor 1 (alpha) 0.988
Bglap bone gamma carboxyglutamate protein 0.987
Ptgs2 prostaglandin-endoperoxide synthase 2 0.986
Fshr follicle stimulating hormone receptor 0.983
Clock circadian locomotor output cycles kaput 0.982
Prlr prolactin receptor 0.981
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.980
Pparg peroxisome proliferator activated receptor gamma 0.978
Vegfa vascular endothelial growth factor A 0.975
Jak2 Janus kinase 2 0.971
Grb2 growth factor receptor bound protein 2 0.968
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.959
Fyn Fyn proto-oncogene 0.955
Lhcgr luteinizing hormone/choriogonadotropin receptor 0.946
Stat3 signal transducer and activator of transcription 3 0.929
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.922
Smad3 MAD homolog 3 (Drosophila) 0.913
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.911
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.906
Kiss1 KiSS-1 metastasis-suppressor 0.904
Pik3r1 phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha) 0.900
Kiss1r KISS1 receptor 0.889
Il1r1 interleukin 1 receptor, type I 0.888
Vhl von Hippel-Lindau tumor suppressor 0.876
Gdnf glial cell line derived neurotrophic factor 0.857
Mark4 MAP/microtubule affinity-regulating kinase 4 0.854
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 0.854
Csf1 colony stimulating factor 1 (macrophage) 0.851
Cbl Casitas B-lineage lymphoma 0.822
Bcl2 B-cell leukemia/lymphoma 2 0.819
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.810
Grb10 growth factor receptor bound protein 10 0.803
Irs2 insulin receptor substrate 2 0.795
Sim1 single-minded homolog 1 (Drosophila) 0.795
Il2rg interleukin 2 receptor, gamma chain 0.792
Pnpla2 patatin-like phospholipase domain containing 2 0.786
Slc12a1 solute carrier family 12, member 1 0.783
Plcg1 phospholipase C, gamma 1 0.772
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.748
Egfr epidermal growth factor receptor 0.748
Stat5a signal transducer and activator of transcription 5A 0.743
Efnb2 ephrin B2 0.740
C1qc complement component 1, q subcomponent, C chain 0.698
Cdkn1b cyclin-dependent kinase inhibitor 1B 0.698
Ahr aryl-hydrocarbon receptor 0.684
Ren1 renin 1 structural 0.682
Agt angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.678
Hif1a hypoxia inducible factor 1, alpha subunit 0.676
Ptk2 PTK2 protein tyrosine kinase 2 0.657
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 0.651
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.647
Cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.642
Akt1 thymoma viral proto-oncogene 1 0.633
Nos2 nitric oxide synthase 2, inducible 0.623
Tgfbr3 transforming growth factor, beta receptor III 0.618
Mc2r melanocortin 2 receptor 0.607
Apc adenomatosis polyposis coli 0.606
Cry1 cryptochrome 1 (photolyase-like) 0.595
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.588
Cdh5 cadherin 5 0.583
Per2 period homolog 2 (Drosophila) 0.578
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic 0.575
Agtr1a angiotensin II receptor, type 1a 0.567
Stat5b signal transducer and activator of transcription 5B 0.566
Gab1 growth factor receptor bound protein 2-associated protein 1 0.561
Per1 period homolog 1 (Drosophila) 0.557
Pomc pro-opiomelanocortin-alpha 0.555
C1qb complement component 1, q subcomponent, beta polypeptide 0.541
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.534
Esr2 estrogen receptor 2 (beta) 0.534
Amhr2 anti-Mullerian hormone type 2 receptor 0.531
Phox2b paired-like homeobox 2b 0.518
Fst follistatin 0.502
Inhba inhibin beta-A 0.500
Kdr kinase insert domain protein receptor 0.496
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.495
Tgfb1 transforming growth factor, beta 1 0.488
C1qa complement component 1, q subcomponent, alpha polypeptide 0.476
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.476
Shc1 src homology 2 domain-containing transforming protein C1 0.444
Src Rous sarcoma oncogene 0.442
Alb albumin 0.432
Fbxl3 F-box and leucine-rich repeat protein 3 0.430
Inha inhibin alpha 0.426
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.426
Adra1b adrenergic receptor, alpha 1b 0.420
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.417
Mup4 major urinary protein 4 0.414
Igf1 insulin-like growth factor 1 0.409
Ubc ubiquitin C 0.401
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
rskn-2 Protein RSKN-2 0.077
oac-46 Protein OAC-46 0.076
cat-1 Protein CAT-1 0.063
ptr-11 Protein PTR-11 0.063
let-60 Protein LET-60 0.062
hlh-14 Protein HLH-14 0.051
nas-38 Protein NAS-38 0.047
hlh-2 Protein HLH-2 0.045
K02A6.2 Protein K02A6.2 0.045
nhr-50 Protein NHR-50 0.045
obr-3 Protein OBR-3 0.042
daf-2 Protein DAF-2 0.041
daf-7 Protein DAF-7 0.039
unc-104 Protein UNC-104 0.036
ZK909.3 Protein ZK909.3 0.036
tpa-1 Protein TPA-1 0.036
ccch-1 Protein CCCH-1 0.034
nhr-6 Protein NHR-6 0.033
exc-5 Protein EXC-5 0.033
R13H4.5 Protein R13H4.5 0.033
CELE_F44G3.7 Protein F44G3.7 0.033
che-13 Protein CHE-13 0.032
K02G10.5 Protein K02G10.5 0.031
che-3 Protein CHE-3 0.030
ifg-1 Protein IFG-1 0.029
Y32F6B.1 Protein Y32F6B.1 0.029
T19A5.3 Protein T19A5.3 0.029
T25F10.3 Protein T25F10.3 0.029
nfm-1 Protein NFM-1 0.029
C35C5.3 Protein C35C5.3 0.027
osm-1 Protein OSM-1 0.027
F02A9.1 Protein F02A9.1 0.026
odd-2 Protein ODD-2 0.026
sel-10 Protein SEL-10 0.026
daf-6 Protein DAF-6 0.026
tag-196 Protein TAG-196 0.025
CELE_C08F8.6 Protein C08F8.6 0.025
glo-4 Protein GLO-4 0.025
osm-6 Protein OSM-6 0.024
K03E6.7 Protein K03E6.7 0.023
pde-2 Protein PDE-2 0.023
daf-16 Protein DAF-16 0.022
akt-2 Protein AKT-2 0.021
nhr-67 Protein NHR-67 0.021
CELE_C28D4.8 Protein C28D4.8 0.021
Y67D8B.4 Protein Y67D8B.4 0.020
che-2 Protein CHE-2 0.020
mec-2 Protein MEC-2 0.020
CELE_F23C8.7 Protein F23C8.7 0.019
T22C8.6 Protein T22C8.6 0.019
F28H7.8 Protein F28H7.8 0.019
C03H12.1 Protein C03H12.1 0.019
bar-1 Protein BAR-1 0.019
ptr-6 Protein PTR-6 0.018
C35B1.7 Protein C35B1.7 0.018
pry-1 Protein PRY-1 0.018
rme-4 Protein RME-4 0.018
R05G6.9 Protein R05G6.9 0.018
CELE_Y11D7A.9 Protein Y11D7A.9 0.018
F18H3.4 Protein F18H3.4 0.018
goa-1 Protein GOA-1 0.018
pes-1 Protein PES-1 0.018
CELE_M05D6.3 Protein M05D6.3 0.017
plc-3 Protein PLC-3 0.017
kin-29 Protein KIN-29 0.017
R12G8.1 Protein R12G8.1 0.017
age-1 Protein AGE-1 0.017
elt-6 Protein ELT-6 0.017
acs-20 Protein ACS-20 0.016
R09B5.11 Protein R09B5.11 0.016
Y73F4A.3 Protein Y73F4A.3 0.016
F47D12.6 Protein F47D12.6 0.016
apc-2 Protein APC-2 0.016
nhr-45 Protein NHR-45 0.016
nhx-9 Protein NHX-9 0.015
ZK669.5 Protein ZK669.5 0.015
pkg-1 Protein PKG-1 0.015
CELE_K03H1.10 Protein K03H1.10 0.015
wrt-6 Protein WRT-6 0.015
C47D2.1 Protein C47D2.1 0.015
R09A1.2 Protein R09A1.2 0.015
W09D12.1 Protein W09D12.1 0.014
C15C6.1 Protein C15C6.1 0.014
soc-2 Protein SOC-2 0.014
hmg-1.2 Protein HMG-1.2 0.014
sym-4 Protein SYM-4 0.014
daf-4 Protein DAF-4 0.014
sos-1 Protein SOS-1 0.014
F26F12.3 Protein F26F12.3 0.014
mbk-2 Protein MBK-2 0.014
CELE_ZK337.2 Protein ZK337.2 0.013
F46H5.2 Protein F46H5.2 0.013
frpr-1 Protein FRPR-1 0.013
fos-1 Protein FOS-1 0.013
wrn-1 Protein WRN-1 0.013
E02H9.3 Protein E02H9.3 0.013
zfp-1 Protein ZFP-1 0.013
CELE_C27D8.2 Protein C27D8.2 0.013
F53A9.2 Protein F53A9.2 0.013
clec-136 Protein CLEC-136 0.013
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Danio rerio
Name Description Probability Func Analog Organism
prox1 prospero-related homeobox gene 1 0.147
mmp9 matrix metalloproteinase 9 0.103
gh1 growth hormone 1 0.086
col5a1 procollagen, type V, alpha 1 0.057
igf1 insulin-like growth factor 1 0.055
ptpra protein tyrosine phosphatase, receptor type, A 0.052
slc2a10 solute carrier family 2 (facilitated glucose transporter), member 10 0.050
ptk2.1 protein tyrosine kinase 2a 0.048
notch1b notch homolog 1b 0.047
per2 period homolog 2 (Drosophila) 0.041
si:rp71-39b20.7 si:rp71-39b20.7 0.040
adipoql adiponectin, C1Q and collagen domain containing, like 0.037
efnb2a ephrin B2a 0.036
pou1f1 POU domain, class 1, transcription factor 1 0.034
il6st interleukin 6 signal transducer 0.033
epas1b endothelial PAS domain protein 1b 0.032
cyp1a cytochrome P450, family 1, subfamily A 0.031
gpia glucose phosphate isomerase a 0.030
cry3 cryptochrome 3 0.026
col12a1 collagen, type XII, alpha 1 0.026
flt1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.025
spi1 spleen focus forming virus (SFFV) proviral integration oncogene spi1 0.025
met met proto-oncogene (hepatocyte growth factor receptor) 0.023
cdh5 cadherin 5 0.023
plxnb2a plexin b2a 0.022
lpp LIM domain containing preferred translocation partner in lipoma 0.022
socs3a suppressor of cytokine signaling 3a 0.022
adipor2 adiponectin receptor 2 0.020
sox9a SRY-box containing gene 9a 0.020
crygm3 crystallin, gamma M3 0.020
ins preproinsulin 0.020
gnrh3 gonadotropin-releasing hormone 3 0.018
tgfbr2 transforming growth factor, beta receptor II 0.017
tnfa tumor necrosis factor a (TNF superfamily, member 2) 0.017
gnrh2 gonadotropin-releasing hormone 2 0.016
nrg1 neuregulin 1 0.016
vdra vitamin D receptor a 0.016
nt5e 5'-nucleotidase, ecto (CD73) 0.016
rx1 retinal homeobox gene 1 0.016
ppp3cca protein phosphatase 3, catalytic subunit, gamma isozyme, a 0.015
sst2 somatostatin 2 0.014
tm4sf4 transmembrane 4 L six family member 4 0.013
aox3 aldehyde oxidase 3 0.013
crygm2d11 crystallin, gamma M2d11 0.013
cx43 connexin 43 0.013
LOC100003514 protein kinase C alpha type-like 0.013
si:ch211-212m21.5 si:ch211-212m21.5 0.013
mbp myelin basic protein 0.012
crygm2d10 crystallin, gamma M2d10 0.012
sec24c SEC24 family, member C (S. cerevisiae) 0.012
nadl1.1 neural adhesion molecule L1.1 0.012
mecp2 methyl CpG binding protein 2 0.012
egr1 early growth response 1 0.012
crygm2b crystallin, gamma M2b 0.012
gnrhr4 gonadotropin releasing hormone receptor 4 0.012
crygmxl2 crystallin, gamma MX, like 2 0.012
atp2b4 ATPase, Ca++ transporting, plasma membrane 4 0.012
pomca proopiomelanocortin a 0.012
zgc:63721 zgc:63721 0.011
lepr leptin receptor 0.011
tie2 endothelium-specific receptor tyrosine kinase 2 0.011
esr2a estrogen receptor 2a 0.011
tie1 endothelium-specific receptor tyrosine kinase 1 0.011
kif5bb kinesin family member 5B, b 0.011
rdh8 retinol dehydrogenase 8 0.011
crygm2d16 crystallin, gamma M2d16 0.010
hif1al hypoxia-inducible factor 1, alpha subunit, like 0.010
ntrk2b neurotrophic tyrosine kinase, receptor, type 2b 0.010
csad cysteine sulfinic acid decarboxylase 0.010
ptprf protein tyrosine phosphatase, receptor type, F 0.010
crygm6 crystallin, gamma M6 0.010
irf9 interferon regulatory factor 9 0.010
socs3b suppressor of cytokine signaling 3b 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.796
InR Insulin-like receptor 0.414
Akt1 CG4006 gene product from transcript CG4006-RA 0.362
Gyc76C Guanylyl cyclase at 76C 0.320
Mad Mothers against dpp 0.312
Tequila CG4821 gene product from transcript CG4821-RE 0.294
Ilp2 Insulin-like peptide 2 0.261
Rac1 CG2248 gene product from transcript CG2248-RA 0.243
if inflated 0.218
Tbh Tyramine beta hydroxylase 0.211
ey eyeless 0.201
CG17450 CG17450 gene product from transcript CG17450-RB 0.196
jeb jelly belly 0.188
S6k RPS6-p70-protein kinase 0.176
dm diminutive 0.175
Spargel CG9809 gene product from transcript CG9809-RB 0.155
fra frazzled 0.152
sNPF-R short neuropeptide F receptor 0.148
drk downstream of receptor kinase 0.142
Thor CG8846 gene product from transcript CG8846-RA 0.140
sav salvador 0.133
Rho1 CG8416 gene product from transcript CG8416-RB 0.117
mbc myoblast city 0.116
MED14 Mediator complex subunit 14 0.111
Yp3 Yolk protein 3 0.109
Lnk CG17367 gene product from transcript CG17367-RC 0.098
CycG Cyclin G 0.098
Ilp6 Insulin-like peptide 6 0.095
mav maverick 0.093
usp ultraspiracle 0.089
Ilp5 Insulin-like peptide 5 0.087
CG13310 CG13310 gene product from transcript CG13310-RA 0.085
rols rolling pebbles 0.084
CG13253 CG13253 gene product from transcript CG13253-RB 0.083
Ilp3 Insulin-like peptide 3 0.078
nej nejire 0.073
Dad Daughters against dpp 0.071
Hnf4 Hepatocyte nuclear factor 4 0.068
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.068
CG3004 CG3004 gene product from transcript CG3004-RA 0.067
CG14869 CG14869 gene product from transcript CG14869-RB 0.067
ash2 absent, small, or homeotic discs 2 0.066
CG6283 CG6283 gene product from transcript CG6283-RA 0.066
pico CG11940 gene product from transcript CG11940-RA 0.064
path pathetic 0.064
Kr-h1 Kruppel homolog 1 0.058
babo baboon 0.057
bowl brother of odd with entrails limited 0.055
CG3847 CG3847 gene product from transcript CG3847-RA 0.053
rictor rapamycin-insensitive companion of Tor 0.053
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.053
sxc super sex combs 0.053
Sema-1a CG18405 gene product from transcript CG18405-RD 0.053
CG14837 CG14837 gene product from transcript CG14837-RC 0.052
ppk pickpocket 0.051
ap apterous 0.050
rap retina aberrant in pattern 0.050
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.049
jagn jagunal 0.047
Pten CG5671 gene product from transcript CG5671-RB 0.047
osa CG7467 gene product from transcript CG7467-RD 0.047
LvpH Larval visceral protein H 0.046
CG7033 CG7033 gene product from transcript CG7033-RC 0.045
gig gigas 0.045
melt melted 0.045
p130CAS CG1212 gene product from transcript CG1212-RA 0.045
Ras85D Ras oncogene at 85D 0.044
CG13510 CG13510 gene product from transcript CG13510-RA 0.042
foxo forkhead box, sub-group O 0.041
Su(dx) Suppressor of deltex 0.041
dock dreadlocks 0.040
CycJ Cyclin J 0.040
Tsp Thrombospondin 0.039
Indy I'm not dead yet 0.039
B4 CG9239 gene product from transcript CG9239-RA 0.039
Nf1 Neurofibromin 1 0.039
Mnt CG13316 gene product from transcript CG13316-RD 0.037
CG11486 CG11486 gene product from transcript CG11486-RG 0.036
not non-stop 0.036
CG11399 CG11399 gene product from transcript CG11399-RB 0.035
Atg8a Autophagy-specific gene 8a 0.035
cpb capping protein beta 0.035
egl egalitarian 0.035
Jarid2 CG3654 gene product from transcript CG3654-RD 0.034
Hr96 Hormone receptor-like in 96 0.034
CG14815 CG14815 gene product from transcript CG14815-RA 0.034
Pgk Phosphoglycerate kinase 0.034
myoglianin CG1838 gene product from transcript CG1838-RD 0.034
tim timeless 0.034
CG42351 CG42351 gene product from transcript CG42351-RG 0.033
ImpL3 Ecdysone-inducible gene L3 0.033
t tan 0.033
Cdk4 Cyclin-dependent kinase 4 0.033
Vinc Vinculin 0.033
Pk61C Protein kinase 61C 0.033
CG3573 CG3573 gene product from transcript CG3573-RA 0.033
Ada2b CG9638 gene product from transcript CG9638-RA 0.033
l(3)82Fd CG32464 gene product from transcript CG32464-RR 0.032
mtt mangetout 0.032
cer crammer 0.031
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
PTPN1 protein tyrosine phosphatase, non-receptor type 1 1.000
EGFR epidermal growth factor receptor 1.000
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.999
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.996
CREBBP CREB binding protein 0.973
ESR1 estrogen receptor 1 0.958
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.956
BCAR1 breast cancer anti-estrogen resistance 1 0.947
GRB2 growth factor receptor-bound protein 2 0.945
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.927
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.823
INSR insulin receptor 0.818
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.763
NCOA1 nuclear receptor coactivator 1 0.733
RXRA retinoid X receptor, alpha 0.727
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.726
GHR growth hormone receptor 0.701
SMAD3 SMAD family member 3 0.661
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.608
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.603
CAV1 caveolin 1, caveolae protein, 22kDa 0.588
GRB10 growth factor receptor-bound protein 10 0.579
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.558
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.504
NCF1 neutrophil cytosolic factor 1 0.504
IRS2 insulin receptor substrate 2 0.477
SOCS3 suppressor of cytokine signaling 3 0.469
SOCS1 suppressor of cytokine signaling 1 0.452
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.420
JAK2 Janus kinase 2 0.370
IGF2R insulin-like growth factor 2 receptor 0.364
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.337
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.325
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.313
GSK3B glycogen synthase kinase 3 beta 0.292
IRS1 insulin receptor substrate 1 0.285
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.270
NCOR2 nuclear receptor corepressor 2 0.267
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.265
EPOR erythropoietin receptor 0.247
TOB1 transducer of ERBB2, 1 0.245
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.243
CFLAR CASP8 and FADD-like apoptosis regulator 0.242
SIRT1 sirtuin 1 0.241
NCOA2 nuclear receptor coactivator 2 0.239
ATF4 activating transcription factor 4 (tax-responsive enhancer element B67) 0.237
PAG1 phosphoprotein associated with glycosphingolipid microdomains 1 0.226
AR androgen receptor 0.224
WDYHV1 WDYHV motif containing 1 0.224
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.223
RARA retinoic acid receptor, alpha 0.222
STAT1 signal transducer and activator of transcription 1, 91kDa 0.219
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.211
SH2B1 SH2B adaptor protein 1 0.210
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.205
FBXW11 F-box and WD repeat domain containing 11 0.199
RORA RAR-related orphan receptor A 0.191
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.190
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.190
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.189
NCK1 NCK adaptor protein 1 0.186
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.181
VAV1 vav 1 guanine nucleotide exchange factor 0.177
PLCG1 phospholipase C, gamma 1 0.175
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.171
KAT2B K(lysine) acetyltransferase 2B 0.169
BCL2 B-cell CLL/lymphoma 2 0.166
PTPRB protein tyrosine phosphatase, receptor type, B 0.165
GRB7 growth factor receptor-bound protein 7 0.165
WRN Werner syndrome, RecQ helicase-like 0.163
REL v-rel reticuloendotheliosis viral oncogene homolog (avian) 0.161
PTK2 PTK2 protein tyrosine kinase 2 0.158
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.157
BCL3 B-cell CLL/lymphoma 3 0.148
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.147
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.144
RHOU ras homolog gene family, member U 0.139
RICTOR RPTOR independent companion of MTOR, complex 2 0.139
SORBS3 sorbin and SH3 domain containing 3 0.138
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.136
PRKD2 protein kinase D2 0.135
SKP1 S-phase kinase-associated protein 1 0.130
ANGPT2 angiopoietin 2 0.130
TTR transthyretin 0.128
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.126
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.124
LAT linker for activation of T cells 0.122
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.119
IL1R1 interleukin 1 receptor, type I 0.118
PTK2B PTK2B protein tyrosine kinase 2 beta 0.115
GH1 growth hormone 1 0.114
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2 0.114
PRKCA protein kinase C, alpha 0.113
EGR3 early growth response 3 0.110
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.108
EPAS1 endothelial PAS domain protein 1 0.103
LIMS1 LIM and senescent cell antigen-like domains 1 0.103
CREB1 cAMP responsive element binding protein 1 0.102
NME1 non-metastatic cells 1, protein (NM23A) expressed in 0.102
EIF4E eukaryotic translation initiation factor 4E 0.099
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 0.891
Akr1c18 aldo-keto reductase family 1, member C18 0.861
Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 0.834
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.800
Il5 interleukin 5 0.767
Pla2g2c phospholipase A2, group IIC 0.764
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.753
Ugt2b UDP glycosyltransferase 2 family, polypeptide B 0.752
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.751
Mef2d myocyte enhancer factor 2D 0.740
Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 0.739
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.739
Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 0.696
Nfia nuclear factor I/A 0.696
Fam38b family with sequence similarity 38, member B 0.669
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.666
Fabp1 fatty acid binding protein 1, liver 0.665
Star steroidogenic acute regulatory protein 0.664
Egr1 early growth response 1 0.645
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.636
A1i3 alpha-1-inhibitor III 0.636
Agtr1a angiotensin II receptor, type 1a 0.634
Rara retinoic acid receptor, alpha 0.619
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.617
Accn2 amiloride-sensitive cation channel 2, neuronal 0.600
Prdx2 peroxiredoxin 2 0.594
Mgst2 microsomal glutathione S-transferase 2 0.584
Alb albumin 0.582
Stc1 stanniocalcin 1 0.573
Socs3 suppressor of cytokine signaling 3 0.572
Il6 interleukin 6 0.566
Dio2 deiodinase, iodothyronine, type II 0.563
Cyp2d4 cytochrome P450, family 2, subfamily d, polypeptide 4 0.563
Jak2 Janus kinase 2 0.559
Olr837 olfactory receptor 837 0.550
Ap2m1 adaptor-related protein complex 2, mu 1 subunit 0.547
Hipk3 homeodomain interacting protein kinase 3 0.546
Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 0.545
F9 coagulation factor IX 0.535
Apoa4 apolipoprotein A-IV 0.511
RT1-M5 RT1 class Ib, locus M5 0.504
Fbp1 fructose-1,6-bisphosphatase 1 0.502
Junb jun B proto-oncogene 0.500
Gja5 gap junction protein, alpha 5 0.496
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.495
Aqp8 aquaporin 8 0.494
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.486
Anpep alanyl (membrane) aminopeptidase 0.484
Col1a1 collagen, type I, alpha 1 0.484
Fos FBJ osteosarcoma oncogene 0.483
Cyp2b15 cytochrome P450, family 2, subfamily b, polypeptide 15 0.479
C9 complement component 9 0.479
Pnliprp2 pancreatic lipase-related protein 2 0.478
Ptprh protein tyrosine phosphatase, receptor type, H 0.469
Bdkrb1 bradykinin receptor B1 0.468
Cd40lg CD40 ligand 0.468
Egr2 early growth response 2 0.468
Clcn5 chloride channel 5 0.465
Cxcl2 chemokine (C-X-C motif) ligand 2 0.464
Cpb1 carboxypeptidase B1 (tissue) 0.463
LOC494499 LOC494499 protein 0.461
Akr1c14 aldo-keto reductase family 1, member C14 0.461
Cxcl10 chemokine (C-X-C motif) ligand 10 0.459
Ugt1a6 UDP glucuronosyltransferase 1 family, polypeptide A6 0.457
Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 0.457
Eln elastin 0.456
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 0.450
Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 0.449
Sult1a1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.449
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 0.446
Fxyd4 FXYD domain-containing ion transport regulator 4 0.443
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) 0.442
Pnoc prepronociceptin 0.442
Haao 3-hydroxyanthranilate 3,4-dioxygenase 0.441
Ptgs2 prostaglandin-endoperoxide synthase 2 0.439
Rdh7 retinol dehydrogenase 7 0.435
Ppard peroxisome proliferator-activated receptor delta 0.434
Irs1 insulin receptor substrate 1 0.434
Fgg fibrinogen gamma chain 0.430
Prlr prolactin receptor 0.430
Ghr growth hormone receptor 0.426
Gjb3 gap junction protein, beta 3 0.421
Ces1c carboxylesterase 1C 0.419
Gabrp gamma-aminobutyric acid (GABA-A) receptor, pi 0.413
Slc22a7 solute carrier family 22 (organic anion transporter), member 7 0.409
Ugt1a7c UDP glucuronosyltransferase 1 family, polypeptide A7C 0.409
Icam1 intercellular adhesion molecule 1 0.407
Serpina3m serine (or cysteine) proteinase inhibitor, clade A, member 3M 0.407
Atf3 activating transcription factor 3 0.405
Gjb4 gap junction protein, beta 4 0.404
Creb1 cAMP responsive element binding protein 1 0.401
Pebp1 phosphatidylethanolamine binding protein 1 0.401
Gnmt glycine N-methyltransferase 0.400
Egfr epidermal growth factor receptor 0.400
Cga glycoprotein hormones, alpha polypeptide 0.392
Gc group specific component 0.388
Ccl20 chemokine (C-C motif) ligand 20 0.388
Vip vasoactive intestinal peptide 0.387
Slc13a2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2 0.382
Dpep1 dipeptidase 1 (renal) 0.381
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism