The network for 'regulation of glomerular mesangial cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of glomerular mesangial cell proliferation

Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.

Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.999
Shh sonic hedgehog 0.986
Gli3 GLI-Kruppel family member GLI3 0.929
Foxc1 forkhead box C1 0.923
Vegfa vascular endothelial growth factor A 0.860
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.832
Rarb retinoic acid receptor, beta 0.814
Ctnnb1 catenin (cadherin associated protein), beta 1 0.758
Foxc2 forkhead box C2 0.692
Ptgs2 prostaglandin-endoperoxide synthase 2 0.682
Nos3 nitric oxide synthase 3, endothelial cell 0.626
Sox9 SRY-box containing gene 9 0.564
Bmp4 bone morphogenetic protein 4 0.530
Bcl2 B-cell leukemia/lymphoma 2 0.477
Rxra retinoid X receptor alpha 0.425
Pten phosphatase and tensin homolog 0.424
Nab2 Ngfi-A binding protein 2 0.415
Prrx1 paired related homeobox 1 0.389
Apc adenomatosis polyposis coli 0.384
Smo smoothened homolog (Drosophila) 0.380
Pax2 paired box gene 2 0.372
Msx1 homeobox, msh-like 1 0.371
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.357
Bmp7 bone morphogenetic protein 7 0.345
Otx2 orthodenticle homolog 2 (Drosophila) 0.313
Itga3 integrin alpha 3 0.266
Tbx1 T-box 1 0.205
Fgfr1 fibroblast growth factor receptor 1 0.202
Ptch1 patched homolog 1 0.195
Tgfb2 transforming growth factor, beta 2 0.186
Dlx5 distal-less homeobox 5 0.161
Tgfbr2 transforming growth factor, beta receptor II 0.159
Lama5 laminin, alpha 5 0.156
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.149
Vhl von Hippel-Lindau tumor suppressor 0.144
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.127
Tcfap2a transcription factor AP-2, alpha 0.118
Fgfr3 fibroblast growth factor receptor 3 0.110
Notch2 Notch gene homolog 2 (Drosophila) 0.102
Pitx2 paired-like homeodomain transcription factor 2 0.095
Alx1 ALX homeobox 1 0.088
Egr2 early growth response 2 0.083
Gli2 GLI-Kruppel family member GLI2 0.079
Emx2 empty spiracles homolog 2 (Drosophila) 0.079
Lepr leptin receptor 0.077
Prrx2 paired related homeobox 2 0.077
Apoe apolipoprotein E 0.076
Jag1 jagged 1 0.076
Rarg retinoic acid receptor, gamma 0.076
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.075
Rspo2 R-spondin 2 homolog (Xenopus laevis) 0.071
Egr1 early growth response 1 0.069
Rara retinoic acid receptor, alpha 0.068
Pax3 paired box gene 3 0.065
Bmp2 bone morphogenetic protein 2 0.065
Lhx1 LIM homeobox protein 1 0.064
Meox2 mesenchyme homeobox 2 0.064
Trp53 transformation related protein 53 0.063
Bmper BMP-binding endothelial regulator 0.061
Runx2 runt related transcription factor 2 0.059
Nab1 Ngfi-A binding protein 1 0.058
Fos FBJ osteosarcoma oncogene 0.058
Col4a3 collagen, type IV, alpha 3 0.058
Eya1 eyes absent 1 homolog (Drosophila) 0.054
Chrd chordin 0.053
Cd151 CD151 antigen 0.050
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.050
Gja1 gap junction protein, alpha 1 0.049
Smad3 MAD homolog 3 (Drosophila) 0.047
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.044
Pbx1 pre B-cell leukemia transcription factor 1 0.040
Zeb1 zinc finger E-box binding homeobox 1 0.039
Ar androgen receptor 0.038
Gdnf glial cell line derived neurotrophic factor 0.036
Fgf8 fibroblast growth factor 8 0.036
Vangl2 vang-like 2 (van gogh, Drosophila) 0.036
Hand1 heart and neural crest derivatives expressed transcript 1 0.035
Ren1 renin 1 structural 0.029
Tcf21 transcription factor 21 0.029
Hbegf heparin-binding EGF-like growth factor 0.027
Junb Jun-B oncogene 0.027
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.026
Ntf3 neurotrophin 3 0.026
Osr1 odd-skipped related 1 (Drosophila) 0.025
Hoxa1 homeobox A1 0.025
Otx1 orthodenticle homolog 1 (Drosophila) 0.022
Ahr aryl-hydrocarbon receptor 0.022
Fosb FBJ osteosarcoma oncogene B 0.021
C1qb complement component 1, q subcomponent, beta polypeptide 0.021
Apln apelin 0.021
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.021
Hand2 heart and neural crest derivatives expressed transcript 2 0.020
Bmp5 bone morphogenetic protein 5 0.020
Nphs2 nephrosis 2 homolog, podocin (human) 0.020
Mks1 Meckel syndrome, type 1 0.020
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.019
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.019
Gata4 GATA binding protein 4 0.018
Agtr1a angiotensin II receptor, type 1a 0.018
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.018
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 1.000
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 1.000
NRP1 neuropilin 1 1.000
VEGFA vascular endothelial growth factor A 0.999
BMPR1A bone morphogenetic protein receptor, type IA 0.997
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.986
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.958
PGF placental growth factor 0.932
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.902
BMPR1B bone morphogenetic protein receptor, type IB 0.841
SNAI1 snail homolog 1 (Drosophila) 0.736
WFIKKN1 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 0.731
PLCG1 phospholipase C, gamma 1 0.672
PDGFC platelet derived growth factor C 0.501
NOG noggin 0.482
COL2A1 collagen, type II, alpha 1 0.423
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.403
PDGFB platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) 0.358
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.354
COL6A1 collagen, type VI, alpha 1 0.280
EGR3 early growth response 3 0.230
EGR2 early growth response 2 0.221
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.204
PTPRB protein tyrosine phosphatase, receptor type, B 0.203
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.202
LDLR low density lipoprotein receptor 0.198
COL5A1 collagen, type V, alpha 1 0.174
IER2 immediate early response 2 0.161
COL4A1 collagen, type IV, alpha 1 0.160
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.151
FOSB FBJ murine osteosarcoma viral oncogene homolog B 0.150
FOS FBJ murine osteosarcoma viral oncogene homolog 0.107
BMP4 bone morphogenetic protein 4 0.077
JUND jun D proto-oncogene 0.074
ATF3 activating transcription factor 3 0.071
BMP2 bone morphogenetic protein 2 0.058
DDIT4 DNA-damage-inducible transcript 4 0.054
TGFB2 transforming growth factor, beta 2 0.052
ZFYVE9 zinc finger, FYVE domain containing 9 0.049
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.046
EPAS1 endothelial PAS domain protein 1 0.042
FZD4 frizzled homolog 4 (Drosophila) 0.037
MDFI MyoD family inhibitor 0.037
COL1A1 collagen, type I, alpha 1 0.037
BTG2 BTG family, member 2 0.035
HMGA1 high mobility group AT-hook 1 0.032
MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.031
TAOK1 TAO kinase 1 0.031
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.028
ZNF205 zinc finger protein 205 0.028
CDH5 cadherin 5, type 2 (vascular endothelium) 0.025
TBX2 T-box 2 0.025
CSRNP1 cysteine-serine-rich nuclear protein 1 0.025
FLT4 fms-related tyrosine kinase 4 0.025
HIPK2 homeodomain interacting protein kinase 2 0.024
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.023
CRKL v-crk sarcoma virus CT10 oncogene homolog (avian)-like 0.023
SLC6A8 solute carrier family 6 (neurotransmitter transporter, creatine), member 8 0.023
STC2 stanniocalcin 2 0.022
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.022
FOXF1 forkhead box F1 0.021
BMP6 bone morphogenetic protein 6 0.021
DUSP6 dual specificity phosphatase 6 0.020
BHLHE40 basic helix-loop-helix family, member e40 0.020
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.020
PTPRJ protein tyrosine phosphatase, receptor type, J 0.019
NPM3 nucleophosmin/nucleoplasmin 3 0.019
DDIT3 DNA-damage-inducible transcript 3 0.019
COL1A2 collagen, type I, alpha 2 0.019
TRIB1 tribbles homolog 1 (Drosophila) 0.018
ZNF420 zinc finger protein 420 0.018
VEGFC vascular endothelial growth factor C 0.018
COL4A2 collagen, type IV, alpha 2 0.018
NRP2 neuropilin 2 0.017
PTGIS prostaglandin I2 (prostacyclin) synthase 0.016
EDN1 endothelin 1 0.016
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.016
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.016
INHBB inhibin, beta B 0.016
ZFP36 zinc finger protein 36, C3H type, homolog (mouse) 0.015
ROBO4 roundabout homolog 4, magic roundabout (Drosophila) 0.015
LOXL2 lysyl oxidase-like 2 0.015
EFNB3 ephrin-B3 0.015
SOSTDC1 sclerostin domain containing 1 0.015
SLC4A1 solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group) 0.015
BMP3 bone morphogenetic protein 3 0.015
WNT2 wingless-type MMTV integration site family member 2 0.015
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.014
PITX2 paired-like homeodomain 2 0.014
HSPG2 heparan sulfate proteoglycan 2 0.014
STC1 stanniocalcin 1 0.014
FGF4 fibroblast growth factor 4 0.014
WNT11 wingless-type MMTV integration site family, member 11 0.014
HAND1 heart and neural crest derivatives expressed 1 0.013
SLIT2 slit homolog 2 (Drosophila) 0.013
NR4A3 nuclear receptor subfamily 4, group A, member 3 0.013
TGFB3 transforming growth factor, beta 3 0.012
SORBS3 sorbin and SH3 domain containing 3 0.012
ETS2 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) 0.012
HES1 hairy and enhancer of split 1, (Drosophila) 0.012
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Rattus norvegicus
Name Description Probability Func Analog Organism
Fos FBJ osteosarcoma oncogene 0.973
Junb jun B proto-oncogene 0.427
Egr2 early growth response 2 0.333
Btg2 BTG family, member 2 0.175
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.172
Dusp1 dual specificity phosphatase 1 0.089
Egr1 early growth response 1 0.072
Dusp6 dual specificity phosphatase 6 0.062
Ier2 immediate early response 2 0.042
Cyr61 cysteine-rich, angiogenic inducer, 61 0.032
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.027
Zfp36 zinc finger protein 36 0.024
Anxa4 annexin A4 0.021
Mdfic MyoD family inhibitor domain containing 0.020
Atf3 activating transcription factor 3 0.020
Jun Jun oncogene 0.018
Klf4 Kruppel-like factor 4 (gut) 0.013
Plau plasminogen activator, urokinase 0.013
Kcnf1 potassium voltage-gated channel, subfamily F, member 1 0.013
Dusp5 dual specificity phosphatase 5 0.013
Lgals7 lectin, galactoside-binding, soluble, 7 0.013
Cyp11b3 cytochrome P450, family 11, subfamily b, polypeptide 3 0.012
Tspan8 tetraspanin 8 0.012
Ccr2 chemokine (C-C motif) receptor 2 0.011
Plac8 placenta-specific 8 0.011
Krt5 keratin 5 0.011
Serpinb3 serine protease inhibitor B3 0.011
Wnt16 wingless-type MMTV integration site family, member 16 0.011
Wisp2 WNT1 inducible signaling pathway protein 2 0.011
Gng11 guanine nucleotide binding protein (G protein), gamma 11 0.010
Prom2 prominin 2 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism