IMP
Process View
The network for 'embryonic heart tube anterior posterior pattern specification' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
embryonic heart tube anterior posterior pattern specification
The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Shh | sonic hedgehog | 1.000 | |
| Pitx2 | paired-like homeodomain transcription factor 2 | 1.000 | |
| Fgfr2 | fibroblast growth factor receptor 2 | 1.000 | |
| Foxc1 | forkhead box C1 | 1.000 | |
| Gata4 | GATA binding protein 4 | 1.000 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 1.000 | |
| Bmp4 | bone morphogenetic protein 4 | 1.000 | |
| Fgf8 | fibroblast growth factor 8 | 1.000 | |
| Tgfb2 | transforming growth factor, beta 2 | 0.999 | |
| Pax3 | paired box gene 3 | 0.999 | |
| Hand2 | heart and neural crest derivatives expressed transcript 2 | 0.998 | |
| Gli3 | GLI-Kruppel family member GLI3 | 0.997 | |
| Foxc2 | forkhead box C2 | 0.996 | |
| Tbx1 | T-box 1 | 0.996 | |
| Nodal | nodal | 0.996 | |
| Jag1 | jagged 1 | 0.994 | |
| Chrd | chordin | 0.993 | |
| Rxra | retinoid X receptor alpha | 0.993 | |
| Sox9 | SRY-box containing gene 9 | 0.991 | |
| Gata6 | GATA binding protein 6 | 0.989 | |
| Vegfa | vascular endothelial growth factor A | 0.988 | |
| Six1 | sine oculis-related homeobox 1 homolog (Drosophila) | 0.986 | |
| Hand1 | heart and neural crest derivatives expressed transcript 1 | 0.982 | |
| Tcfap2a | transcription factor AP-2, alpha | 0.975 | |
| Pax2 | paired box gene 2 | 0.973 | |
| Hoxa1 | homeobox A1 | 0.972 | |
| Smo | smoothened homolog (Drosophila) | 0.964 | |
| Eya1 | eyes absent 1 homolog (Drosophila) | 0.961 | |
| Rarg | retinoic acid receptor, gamma | 0.936 | |
| Bmp7 | bone morphogenetic protein 7 | 0.909 | |
| Ptpn11 | protein tyrosine phosphatase, non-receptor type 11 | 0.907 | |
| Otx2 | orthodenticle homolog 2 (Drosophila) | 0.902 | |
| Msx1 | homeobox, msh-like 1 | 0.897 | |
| Acvr1 | activin A receptor, type 1 | 0.884 | |
| Isl1 | ISL1 transcription factor, LIM/homeodomain | 0.876 | |
| Rarb | retinoic acid receptor, beta | 0.860 | |
| Pdgfra | platelet derived growth factor receptor, alpha polypeptide | 0.828 | |
| Fgfr1 | fibroblast growth factor receptor 1 | 0.825 | |
| Ctnnb1 | catenin (cadherin associated protein), beta 1 | 0.816 | |
| Mesp1 | mesoderm posterior 1 | 0.802 | |
| Chd7 | chromodomain helicase DNA binding protein 7 | 0.798 | |
| Prrx1 | paired related homeobox 1 | 0.783 | |
| Aldh1a2 | aldehyde dehydrogenase family 1, subfamily A2 | 0.697 | |
| Ednra | endothelin receptor type A | 0.683 | |
| Fgf10 | fibroblast growth factor 10 | 0.670 | |
| Meox2 | mesenchyme homeobox 2 | 0.647 | |
| Cited2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.579 | |
| Ror2 | receptor tyrosine kinase-like orphan receptor 2 | 0.572 | |
| Gsc | goosecoid homeobox | 0.570 | |
| Zic3 | zinc finger protein of the cerebellum 3 | 0.521 | |
| Foxg1 | forkhead box G1 | 0.517 | |
| Zfpm2 | zinc finger protein, multitype 2 | 0.497 | |
| Gbx2 | gastrulation brain homeobox 2 | 0.494 | |
| Zeb1 | zinc finger E-box binding homeobox 1 | 0.465 | |
| Rara | retinoic acid receptor, alpha | 0.454 | |
| Efnb2 | ephrin B2 | 0.454 | |
| Vangl2 | vang-like 2 (van gogh, Drosophila) | 0.434 | |
| Dlx5 | distal-less homeobox 5 | 0.424 | |
| Sox4 | SRY-box containing gene 4 | 0.408 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.397 | |
| Ece1 | endothelin converting enzyme 1 | 0.397 | |
| Gli2 | GLI-Kruppel family member GLI2 | 0.368 | |
| Hey2 | hairy/enhancer-of-split related with YRPW motif 2 | 0.355 | |
| Nos3 | nitric oxide synthase 3, endothelial cell | 0.335 | |
| Ntf3 | neurotrophin 3 | 0.334 | |
| Rspo2 | R-spondin 2 homolog (Xenopus laevis) | 0.296 | |
| Tbx3 | T-box 3 | 0.283 | |
| Msx2 | homeobox, msh-like 2 | 0.275 | |
| Ptch1 | patched homolog 1 | 0.267 | |
| Bmpr1a | bone morphogenetic protein receptor, type 1A | 0.261 | |
| Gja1 | gap junction protein, alpha 1 | 0.252 | |
| Fgfr3 | fibroblast growth factor receptor 3 | 0.208 | |
| Egfr | epidermal growth factor receptor | 0.198 | |
| Hoxa3 | homeobox A3 | 0.190 | |
| Runx2 | runt related transcription factor 2 | 0.187 | |
| Apc | adenomatosis polyposis coli | 0.171 | |
| Nf1 | neurofibromatosis 1 | 0.155 | |
| Lhx1 | LIM homeobox protein 1 | 0.126 | |
| Dnahc5 | dynein, axonemal, heavy chain 5 | 0.120 | |
| Psen1 | presenilin 1 | 0.108 | |
| Klf3 | Kruppel-like factor 3 (basic) | 0.104 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.103 | |
| Foxa2 | forkhead box A2 | 0.102 | |
| Notch1 | Notch gene homolog 1 (Drosophila) | 0.095 | |
| Wt1 | Wilms tumor 1 homolog | 0.093 | |
| Hoxa2 | homeobox A2 | 0.093 | |
| Foxf1a | forkhead box F1a | 0.092 | |
| Six4 | sine oculis-related homeobox 4 homolog (Drosophila) | 0.078 | |
| Prrx2 | paired related homeobox 2 | 0.077 | |
| Gata5 | GATA binding protein 5 | 0.073 | |
| Alx4 | aristaless-like homeobox 4 | 0.072 | |
| Klf1 | Kruppel-like factor 1 (erythroid) | 0.071 | |
| Smad4 | MAD homolog 4 (Drosophila) | 0.070 | |
| Mycn | v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) | 0.069 | |
| Pbx1 | pre B-cell leukemia transcription factor 1 | 0.068 | |
| Smad6 | MAD homolog 6 (Drosophila) | 0.060 | |
| Tcf21 | transcription factor 21 | 0.059 | |
| Nog | noggin | 0.058 | |
| Pitx1 | paired-like homeodomain transcription factor 1 | 0.054 | |
| Fgf3 | fibroblast growth factor 3 | 0.048 |
