The network for 'nephron epithelium morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nephron epithelium morphogenesis

The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.

Mus musculus
Name Description Probability Func Analog Organism
Pax2 paired box gene 2 1.000
Shh sonic hedgehog 1.000
Lhx1 LIM homeobox protein 1 1.000
Fgfr2 fibroblast growth factor receptor 2 1.000
Emx2 empty spiracles homolog 2 (Drosophila) 1.000
Fgf8 fibroblast growth factor 8 1.000
Foxc1 forkhead box C1 1.000
Hoxa11 homeobox A11 1.000
Gli3 GLI-Kruppel family member GLI3 0.999
Gdnf glial cell line derived neurotrophic factor 0.999
Ret ret proto-oncogene 0.999
Wt1 Wilms tumor 1 homolog 0.998
Rarg retinoic acid receptor, gamma 0.998
Pax3 paired box gene 3 0.998
Pax8 paired box gene 8 0.996
Nr5a1 nuclear receptor subfamily 5, group A, member 1 0.993
Hoxa1 homeobox A1 0.992
Hoxd11 homeobox D11 0.991
Pbx1 pre B-cell leukemia transcription factor 1 0.991
Otx1 orthodenticle homolog 1 (Drosophila) 0.990
Six1 sine oculis-related homeobox 1 homolog (Drosophila) 0.990
Tbx2 T-box 2 0.990
Otx2 orthodenticle homolog 2 (Drosophila) 0.988
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.988
Hoxd3 homeobox D3 0.986
Bcl2 B-cell leukemia/lymphoma 2 0.986
Hoxd9 homeobox D9 0.983
Pitx2 paired-like homeodomain transcription factor 2 0.982
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.981
Rara retinoic acid receptor, alpha 0.979
Hand1 heart and neural crest derivatives expressed transcript 1 0.978
Nog noggin 0.977
Bmp4 bone morphogenetic protein 4 0.973
Hand2 heart and neural crest derivatives expressed transcript 2 0.973
Hes1 hairy and enhancer of split 1 (Drosophila) 0.971
Hoxb3 homeobox B3 0.971
Sox2 SRY-box containing gene 2 0.971
Ctnnb1 catenin (cadherin associated protein), beta 1 0.970
Foxc2 forkhead box C2 0.969
Vegfa vascular endothelial growth factor A 0.967
Hoxb4 homeobox B4 0.966
Tcf21 transcription factor 21 0.965
Snai1 snail homolog 1 (Drosophila) 0.962
Hoxa3 homeobox A3 0.961
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.957
Lmx1b LIM homeobox transcription factor 1 beta 0.957
Nkx2-1 NK2 homeobox 1 0.956
Hoxa10 homeobox A10 0.947
Hoxd13 homeobox D13 0.942
Lhx3 LIM homeobox protein 3 0.942
Fgfr1 fibroblast growth factor receptor 1 0.942
Hoxd4 homeobox D4 0.936
Nos3 nitric oxide synthase 3, endothelial cell 0.936
Gli2 GLI-Kruppel family member GLI2 0.933
Tcfap2a transcription factor AP-2, alpha 0.932
Hoxb6 homeobox B6 0.931
Pax6 paired box gene 6 0.930
Eya1 eyes absent 1 homolog (Drosophila) 0.930
Hoxc8 homeobox C8 0.925
Gbx2 gastrulation brain homeobox 2 0.925
Hes5 hairy and enhancer of split 5 (Drosophila) 0.924
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.924
Smad3 MAD homolog 3 (Drosophila) 0.921
Foxa2 forkhead box A2 0.916
Lmx1a LIM homeobox transcription factor 1 alpha 0.915
Flt4 FMS-like tyrosine kinase 4 0.911
Bnc1 basonuclin 1 0.904
Emx1 empty spiracles homolog 1 (Drosophila) 0.901
Smad1 MAD homolog 1 (Drosophila) 0.898
Hoxd10 homeobox D10 0.898
Wnt4 wingless-related MMTV integration site 4 0.892
Hoxa5 homeobox A5 0.891
Gata6 GATA binding protein 6 0.884
Rarb retinoic acid receptor, beta 0.879
Sall4 sal-like 4 (Drosophila) 0.877
Tbx1 T-box 1 0.877
Rxra retinoid X receptor alpha 0.876
Hoxa9 homeobox A9 0.872
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.868
Hoxa2 homeobox A2 0.866
Smad6 MAD homolog 6 (Drosophila) 0.860
Efnb2 ephrin B2 0.849
Mycn v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 0.847
Dkk1 dickkopf homolog 1 (Xenopus laevis) 0.841
Wnt6 wingless-related MMTV integration site 6 0.840
Isl1 ISL1 transcription factor, LIM/homeodomain 0.834
Fgf10 fibroblast growth factor 10 0.834
Lama5 laminin, alpha 5 0.834
Ntf3 neurotrophin 3 0.829
Jag1 jagged 1 0.826
Hoxb5 homeobox B5 0.824
Tbx3 T-box 3 0.817
Lhx9 LIM homeobox protein 9 0.800
Sox9 SRY-box containing gene 9 0.797
Twist2 twist homolog 2 (Drosophila) 0.793
Ren1 renin 1 structural 0.784
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.779
Hoxa13 homeobox A13 0.778
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.773
Hoxc5 homeobox C5 0.768
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
myod1 myogenic differentiation 1 0.994
osr2 odd-skipped related 2 (Drosophila) 0.985
bmp2a bone morphogenetic protein 2a 0.979
prdm1a PR domain containing 1a, with ZNF domain 0.976
pax2a paired box gene 2a 0.971
wt1b wilms tumor 1b 0.963
bmp4 bone morphogenetic protein 4 0.949
gyltl1b glycosyltransferase-like 1b 0.895
wnt5b wingless-type MMTV integration site family, member 5b 0.891
eya1 eyes absent homolog 1 0.885
tbx1 T-box 1 0.882
wt1a wilms tumor 1a 0.881
cdh2 cadherin 2, neuronal 0.851
bmp2b bone morphogenetic protein 2b 0.832
hoxd4a homeo box D4a 0.821
nkx3.2 NK3 homeobox 2 0.812
six4b sine oculis homeobox homolog 4b 0.786
aldh1a2 aldehyde dehydrogenase 1 family, member A2 0.764
etv2 ets variant gene 2 0.756
chd chordin 0.742
notch3 notch homolog 3 0.721
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.701
kdrl kinase insert domain receptor like 0.699
lhx1a LIM homeobox 1a 0.664
aplnrb apelin receptor b 0.659
jag2 jagged 2 0.659
hoxa9a homeo box A9a 0.641
tbx18 T-box 18 0.631
gbx2 gastrulation brain homeo box 2 0.579
pcdh8 protocadherin 8 0.577
shha sonic hedgehog a 0.559
fgf10a fibroblast growth factor 10a 0.546
osr1 odd-skipped related 1 (Drosophila) 0.521
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.514
hoxa9b homeo box A9b 0.495
klf4 Kruppel-like factor 4 0.475
notch1a notch homolog 1a 0.473
lef1 lymphocyte enhancer binding factor 1 0.461
pitx3 paired-like homeodomain transcription factor 3 0.448
hnf1bb HNF1 homeobox Bb 0.426
wnt2ba wingless-type MMTV integration site family, member 2Ba 0.413
foxj1a forkhead box J1a 0.411
hoxd10a homeo box D10a 0.403
hoxc6a homeo box C6a 0.390
six2a sine oculis-related homeobox 2a 0.390
dkk1b dickkopf 1b 0.384
hapln1a hyaluronan and proteoglycan link protein 1a 0.378
foxi1 forkhead box I1 0.373
elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) 0.368
fgf3 fibroblast growth factor 3 0.366
tbx5a T-box 5a 0.366
hnf1ba HNF1 homeobox Ba 0.364
spry1 sprouty homolog 1 (Drosophila) 0.363
foxd3 forkhead box D3 0.358
twist3 twist3 0.349
tbx16 T-box gene 16 0.348
hoxd12a homeo box D12a 0.340
sim1a single-minded homolog 1a (Drosophila) 0.339
pax8 paired box gene 8 0.338
hoxa13b homeo box A13b 0.329
lrrc50 leucine rich repeat containing 50 0.328
wnt10a wingless-type MMTV integration site family, member 10a 0.325
tll1 tolloid-like 1 0.319
hoxa11b homeo box A11b 0.310
pea3 ETS-domain transcription factor pea3 0.296
wnt1 wingless-type MMTV integration site family, member 1 0.292
mib mind bomb 0.289
aplnra apelin receptor a 0.274
hoxa10b homeo box A10b 0.273
dlx4b distal-less homeobox gene 4b 0.269
foxn4 forkhead box N4 0.269
her12 hairy-related 12 0.269
hoxc9a homeo box C9a 0.267
dlc deltaC 0.260
atoh1a atonal homolog 1a 0.251
twist2 twist2 0.250
twist1a twist1a 0.243
jag1b jagged 1b 0.240
spaw southpaw 0.239
dact2 dapper homolog 2, antagonist of beta-catenin (xenopus) 0.235
trpm7 transient receptor potential cation channel, subfamily M, member 7 0.228
flr fleer 0.219
znf503 zinc finger protein 503 0.219
itga3b integrin, alpha 3b 0.217
wnt3a wingless-type MMTV integration site family, member 3A 0.215
mecom MDS1 and EVI1 complex locus 0.215
igfbp3 insulin-like growth factor binding protein 3 0.214
hoxb5a homeo box B5a 0.212
gdnf glial cell derived neurotrophic factor 0.212
hoxd13a homeo box D13a 0.210
hmx4 H6 family homeobox 4 0.210
pkd2 polycystic kidney disease 2 0.206
evx1 even-skipped homeobox 1 0.205
ptgs1 prostaglandin-endoperoxide synthase 1 0.200
hmx1 H6 homeo box 1 0.199
hoxa11a homeo box A11a 0.196
foxo3b forkhead box O3b 0.193
runx2a runt-related transcription factor 2a 0.192
wtip Wilms tumor 1 interacting protein 0.190
hoxd11a homeo box D11a 0.178
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Drosophila melanogaster
Name Description Probability Func Analog Organism
ci cubitus interruptus 0.996
E(spl) Enhancer of split 0.995
HLHm7 E(spl) region transcript m7 0.981
HLHmgamma E(spl) region transcript mgamma 0.932
wg wingless 0.926
HLHmdelta E(spl) region transcript mdelta 0.899
hh hedgehog 0.874
HLHmbeta E(spl) region transcript mbeta 0.863
hth homothorax 0.859
bowl brother of odd with entrails limited 0.796
HLHm3 E(spl) region transcript m3 0.722
en engrailed 0.709
m2 E(spl) region transcript m2 0.553
fng fringe 0.488
Ser Serrate 0.486
klu klumpfuss 0.486
malpha E(spl) region transcript malpha 0.473
HLHm5 E(spl) region transcript m5 0.439
kni knirps 0.393
dpp decapentaplegic 0.383
Tom Twin of m4 0.349
m4 E(spl) region transcript m4 0.317
Mad Mothers against dpp 0.300
Dad Daughters against dpp 0.278
hpo hippo 0.260
eya eyes absent 0.255
sc scute 0.250
al aristaless 0.249
Dfd Deformed 0.246
argos CG4531 gene product from transcript CG4531-RA 0.242
os outstretched 0.235
sna snail 0.230
vg vestigial 0.228
ac achaete 0.222
ds dachsous 0.221
Nrx-IV Neurexin IV 0.202
so sine oculis 0.169
tup tailup 0.168
ato atonal 0.161
bib big brain 0.136
inv invected 0.131
sqh spaghetti squash 0.130
ara araucan 0.128
Ubx Ultrabithorax 0.125
mirr mirror 0.123
Btk29A Btk family kinase at 29A 0.121
emc extra macrochaetae 0.115
ex expanded 0.113
gro groucho 0.113
opa odd paired 0.112
dy dusky 0.106
ft fat 0.106
eg eagle 0.106
rpr reaper 0.102
slp1 sloppy paired 1 0.099
gbb glass bottom boat 0.093
tsh teashirt 0.092
tkv thickveins 0.092
Egfr Epidermal growth factor receptor 0.091
ss spineless 0.087
gcm glial cells missing 0.086
caup caupolican 0.082
Cul-2 Cullin-2 0.082
gt giant 0.079
JIL-1 CG6297 gene product from transcript CG6297-RA 0.078
egh egghead 0.077
bi bifid 0.077
noc no ocelli 0.076
Fas2 Fasciclin 2 0.075
loqs loquacious 0.075
esg escargot 0.074
eyg eyegone 0.074
odd odd skipped 0.071
byn brachyenteron 0.071
stck steamer duck 0.070
tap target of Poxn 0.070
ap apterous 0.068
kn knot 0.068
Shaw Shaker cognate w 0.067
scw screw 0.065
orb oo18 RNA-binding protein 0.063
ase asense 0.063
tsl torso-like 0.063
ems empty spiracles 0.062
drm drumstick 0.059
bab1 bric a brac 1 0.058
Hs3st-B Heparan sulfate 3-O sulfotransferase-B 0.057
toc toucan 0.056
fj four-jointed 0.056
BobA Brother of Bearded A 0.056
Dll Distal-less 0.056
dm diminutive 0.056
sd scalloped 0.055
pnr pannier 0.055
tra transformer 0.054
sog short gastrulation 0.054
Npc1b Niemann-Pick type C-1b 0.054
put punt 0.053
grh grainy head 0.053
zpg zero population growth 0.052
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Homo sapiens
Name Description Probability Func Analog Organism
FGFR2 fibroblast growth factor receptor 2 1.000
CUL3 cullin 3 0.938
FLT1 fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) 0.886
KLHL12 kelch-like 12 (Drosophila) 0.832
BMPR1A bone morphogenetic protein receptor, type IA 0.716
FGFR1 fibroblast growth factor receptor 1 0.666
MEIS1 Meis homeobox 1 0.659
EGR2 early growth response 2 0.566
MEOX1 mesenchyme homeobox 1 0.521
FGF8 fibroblast growth factor 8 (androgen-induced) 0.517
NRP1 neuropilin 1 0.513
MEIS2 Meis homeobox 2 0.507
ADAM17 ADAM metallopeptidase domain 17 0.492
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.487
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.479
NKX2-1 NK2 homeobox 1 0.448
MAGED2 melanoma antigen family D, 2 0.393
DAPK1 death-associated protein kinase 1 0.393
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like 0.358
VEGFA vascular endothelial growth factor A 0.343
KLHL2 kelch-like 2, Mayven (Drosophila) 0.327
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.324
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.310
MSN moesin 0.307
PAX8 paired box 8 0.298
HOXA10 homeobox A10 0.296
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.285
COL2A1 collagen, type II, alpha 1 0.242
PGF placental growth factor 0.230
SMAD3 SMAD family member 3 0.229
BCL2L1 BCL2-like 1 0.213
HOXB5 homeobox B5 0.205
TAOK1 TAO kinase 1 0.192
FGF18 fibroblast growth factor 18 0.183
FGF10 fibroblast growth factor 10 0.175
SOX2 SRY (sex determining region Y)-box 2 0.154
EGR3 early growth response 3 0.154
FGF7 fibroblast growth factor 7 0.153
PJA1 praja ring finger 1 0.141
HMGA2 high mobility group AT-hook 2 0.130
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.108
FGF1 fibroblast growth factor 1 (acidic) 0.102
FGF4 fibroblast growth factor 4 0.101
FGF3 fibroblast growth factor 3 0.101
GLIS2 GLIS family zinc finger 2 0.100
COL7A1 collagen, type VII, alpha 1 0.098
BCAM basal cell adhesion molecule (Lutheran blood group) 0.095
PAX2 paired box 2 0.094
BMP7 bone morphogenetic protein 7 0.090
WNT1 wingless-type MMTV integration site family, member 1 0.089
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.086
ENG endoglin 0.079
ZFYVE9 zinc finger, FYVE domain containing 9 0.076
FOS FBJ murine osteosarcoma viral oncogene homolog 0.067
TSC22D4 TSC22 domain family, member 4 0.066
TIMP3 TIMP metallopeptidase inhibitor 3 0.063
HOXD13 homeobox D13 0.060
NOTCH1 notch 1 0.058
WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 0.058
MMP2 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) 0.058
FOXC2 forkhead box C2 (MFH-1, mesenchyme forkhead 1) 0.056
NFE2L2 nuclear factor (erythroid-derived 2)-like 2 0.055
SKIL SKI-like oncogene 0.053
TGFBR1 transforming growth factor, beta receptor 1 0.048
SFRP1 secreted frizzled-related protein 1 0.048
SIM2 single-minded homolog 2 (Drosophila) 0.047
WNT7A wingless-type MMTV integration site family, member 7A 0.045
EGR1 early growth response 1 0.045
FOXD3 forkhead box D3 0.045
MNX1 motor neuron and pancreas homeobox 1 0.044
HES2 hairy and enhancer of split 2 (Drosophila) 0.043
FGFR3 fibroblast growth factor receptor 3 0.042
TRPC1 transient receptor potential cation channel, subfamily C, member 1 0.041
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.041
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.039
HOXB6 homeobox B6 0.037
FOXA2 forkhead box A2 0.036
PARVA parvin, alpha 0.036
DVL1 dishevelled, dsh homolog 1 (Drosophila) 0.036
SNAI1 snail homolog 1 (Drosophila) 0.036
TGFB3 transforming growth factor, beta 3 0.035
PAX3 paired box 3 0.035
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit 0.034
LBX1 ladybird homeobox 1 0.034
DGCR14 DiGeorge syndrome critical region gene 14 0.032
LMO4 LIM domain only 4 0.032
THBS1 thrombospondin 1 0.031
BMP4 bone morphogenetic protein 4 0.031
SOX1 SRY (sex determining region Y)-box 1 0.030
IHH Indian hedgehog 0.030
GDNF glial cell derived neurotrophic factor 0.028
TP53 tumor protein p53 0.028
WNT10A wingless-type MMTV integration site family, member 10A 0.027
TGFB2 transforming growth factor, beta 2 0.027
INHBB inhibin, beta B 0.027
WNT3 wingless-type MMTV integration site family, member 3 0.026
FOXC1 forkhead box C1 0.026
IRX5 iroquois homeobox 5 0.025
FOXN4 forkhead box N4 0.025
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2) 0.025
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Rattus norvegicus
Name Description Probability Func Analog Organism
Nek9 NIMA (never in mitosis gene a)- related kinase 9 0.018
Hoxc4 homeo box C4 0.016
LOC100365106 rCG32755-like 0.016
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.014
Kcnj1 potassium inwardly-rectifying channel, subfamily J, member 1 0.013
Il1r1 interleukin 1 receptor, type I 0.012
Stat1 signal transducer and activator of transcription 1 0.012
Cad carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase 0.012
Ptger3 prostaglandin E receptor 3 (subtype EP3) 0.011
Krt15 keratin 15 0.011
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.010
Rnf213 ring finger protein 213 0.010
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism