The network for 'positive regulation of nucleotide metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nucleotide metabolic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.

Name Description Probability Func Analog Organism
Kl klotho 0.980
Ctnnb1 catenin (cadherin associated protein), beta 1 0.824
Bcl2 B-cell leukemia/lymphoma 2 0.764
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.731
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.678
Drd2 dopamine receptor D2 0.624
Trp53 transformation related protein 53 0.587
Pax8 paired box gene 8 0.570
Arrb2 arrestin, beta 2 0.562
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.556
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.529
Ccl2 chemokine (C-C motif) ligand 2 0.522
Ar androgen receptor 0.517
Selplg selectin, platelet (p-selectin) ligand 0.515
Pparg peroxisome proliferator activated receptor gamma 0.509
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.481
Tsc1 tuberous sclerosis 1 0.479
Plxnb1 plexin B1 0.474
Bax BCL2-associated X protein 0.467
Nf1 neurofibromatosis 1 0.454
Dlg4 discs, large homolog 4 (Drosophila) 0.440
Efnb2 ephrin B2 0.438
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.431
Grb2 growth factor receptor bound protein 2 0.429
Plxna1 plexin A1 0.422
Bglap bone gamma carboxyglutamate protein 0.412
Chrm1 cholinergic receptor, muscarinic 1, CNS 0.392
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.390
Ilk integrin linked kinase 0.382
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 0.371
Adam19 a disintegrin and metallopeptidase domain 19 (meltrin beta) 0.361
Epha4 Eph receptor A4 0.357
Rac1 RAS-related C3 botulinum substrate 1 0.353
Ntf3 neurotrophin 3 0.345
Hmha1 histocompatibility (minor) HA-1 0.333
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.327
Braf Braf transforming gene 0.325
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.317
Sox10 SRY-box containing gene 10 0.313
Arrb1 arrestin, beta 1 0.310
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a 0.309
Lepr leptin receptor 0.308
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.308
Arpc4 actin related protein 2/3 complex, subunit 4 0.301
Gsk3b glycogen synthase kinase 3 beta 0.292
Adora2a adenosine A2a receptor 0.291
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.290
Esrrb estrogen related receptor, beta 0.281
Sh3bgrl SH3-binding domain glutamic acid-rich protein like 0.280
Rps3 ribosomal protein S3 0.278
Shc3 src homology 2 domain-containing transforming protein C3 0.275
Pnpla2 patatin-like phospholipase domain containing 2 0.272
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.261
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.257
Nf2 neurofibromatosis 2 0.254
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha 0.250
Adra2a adrenergic receptor, alpha 2a 0.249
Arhgef12 Rho guanine nucleotide exchange factor (GEF) 12 0.246
Rasgrp2 RAS, guanyl releasing protein 2 0.241
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.238
Capn2 calpain 2 0.234
Ptgir prostaglandin I receptor (IP) 0.233
Pxn paxillin 0.230
Abcg1 ATP-binding cassette, sub-family G (WHITE), member 1 0.229
Gata5 GATA binding protein 5 0.229
Socs1 suppressor of cytokine signaling 1 0.228
Mdm2 transformed mouse 3T3 cell double minute 2 0.223
Ccl12 chemokine (C-C motif) ligand 12 0.223
Kitl kit ligand 0.213
Plxnd1 plexin D1 0.213
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 0.213
Socs3 suppressor of cytokine signaling 3 0.212
Ednra endothelin receptor type A 0.211
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.210
Fgf10 fibroblast growth factor 10 0.206
Calcrl calcitonin receptor-like 0.206
Kit kit oncogene 0.205
Akt1 thymoma viral proto-oncogene 1 0.205
Kcna4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.203
Adam17 a disintegrin and metallopeptidase domain 17 0.202
Sstr4 somatostatin receptor 4 0.201
Tgfa transforming growth factor alpha 0.199
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.199
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.199
Vav1 vav 1 oncogene 0.199
Tcfcp2l1 transcription factor CP2-like 1 0.198
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 0.198
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.193
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.192
Pten phosphatase and tensin homolog 0.191
Rasa3 RAS p21 protein activator 3 0.191
Stxbp3a syntaxin binding protein 3A 0.190
Vdr vitamin D receptor 0.187
Rasal3 RAS protein activator like 3 0.187
Fgf8 fibroblast growth factor 8 0.185
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.184
Acvr1 activin A receptor, type 1 0.184
Wipf1 WAS/WASL interacting protein family, member 1 0.183
Irf5 interferon regulatory factor 5 0.183
Cd37 CD37 antigen 0.180
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
lag-1 Protein LAG-1 0.140
CELE_F47G4.4 Protein F47G4.4 0.128
let-60 Protein LET-60 0.114
plc-3 Protein PLC-3 0.098
zfp-3 Protein ZFP-3 0.082
unc-53 Protein UNC-53 0.074
egl-18 Protein EGL-18 0.073
itr-1 Protein ITR-1 0.062
goa-1 Protein GOA-1 0.060
unc-26 Protein UNC-26 0.057
pkg-1 Protein PKG-1 0.054
par-6 Protein PAR-6 0.054
mpk-1 Protein MPK-1 0.054
ptp-4 Protein PTP-4 0.053
snf-1 Protein SNF-1 0.053
rps-2 Protein RPS-2 0.052
rig-6 Protein RIG-6 0.051
afd-1 Protein AFD-1 0.051
magi-1 Protein MAGI-1 0.050
mel-28 Protein MEL-28 0.049
egl-36 Protein EGL-36 0.049
sup-17 Protein SUP-17 0.048
T21B6.3 Protein T21B6.3 0.046
unc-79 Protein UNC-79 0.046
zoo-1 Protein ZOO-1 0.045
chc-1 Protein CHC-1 0.045
egrh-1 Protein EGRH-1 0.044
rpm-1 Protein RPM-1 0.043
F28B3.1 Protein F28B3.1 0.040
gar-3 Protein GAR-3 0.039
F52G3.1 Protein F52G3.1 0.038
rhgf-2 Protein RHGF-2 0.037
sem-5 Protein SEM-5 0.035
pry-1 Protein PRY-1 0.034
unc-71 Protein UNC-71 0.034
sad-1 Protein SAD-1 0.034
dpf-3 Protein DPF-3 0.034
panl-3 Protein PANL-3 0.034
eor-2 Protein EOR-2 0.033
nrx-1 Protein NRX-1 0.033
frm-3 Protein FRM-3 0.033
sma-6 Protein SMA-6 0.033
syd-9 Protein SYD-9 0.033
C11E4.6 Protein C11E4.6 0.032
hlh-1 Protein HLH-1 0.032
W07B8.3 Protein W07B8.3 0.032
smp-1 Protein SMP-1 0.031
T23F2.2 Protein T23F2.2 0.030
hmr-1 Protein HMR-1 0.030
ttx-1 Protein TTX-1 0.030
Y55F3BR.8 Protein Y55F3BR.8 0.030
sto-4 Protein STO-4 0.029
act-3 Protein ACT-3 0.028
F28E10.1 Protein F28E10.1 0.028
jnk-1 Protein JNK-1 0.028
unc-115 Protein UNC-115 0.028
atg-2 Protein ATG-2 0.028
aha-1 Protein AHA-1 0.028
CELE_F14E5.2 Protein F14E5.2 0.028
T14B1.1 Protein T14B1.1 0.027
ddr-2 Protein DDR-2 0.027
egl-8 Protein EGL-8 0.027
rgs-6 Protein RGS-6 0.027
gei-8 Protein GEI-8 0.026
rme-4 Protein RME-4 0.026
F35G2.1 Protein F35G2.1 0.026
plc-1 Protein PLC-1 0.025
patr-1 Protein PATR-1 0.025
ast-1 Protein AST-1 0.025
lpd-3 Protein LPD-3 0.025
pqn-39 Protein PQN-39 0.025
Y62E10A.2 Protein Y62E10A.2 0.025
ZK418.7 Protein ZK418.7 0.025
abl-1 Protein ABL-1 0.025
ajm-1 Protein AJM-1 0.024
CELE_Y69A2AR.28 Protein Y69A2AR.28 0.024
ptr-5 Protein PTR-5 0.024
F54D8.6 Protein F54D8.6 0.024
madf-5 Protein MADF-5 0.024
tbc-18 Protein TBC-18 0.024
lin-48 Protein LIN-48 0.024
C30G12.6 Protein C30G12.6 0.024
unc-103 Protein UNC-103 0.024
ist-1 Protein IST-1 0.024
rsbp-1 Protein RSBP-1 0.024
F13H6.1 Protein F13H6.1 0.023
sol-1 Protein SOL-1 0.023
ced-10 Protein CED-10 0.023
tmd-2 Protein TMD-2 0.023
ztf-20 Protein ZTF-20 0.023
acr-2 Protein ACR-2 0.022
sam-10 Protein SAM-10 0.022
fhod-1 Protein FHOD-1 0.022
cdh-9 Protein CDH-9 0.022
shn-1 Protein SHN-1 0.022
stau-1 Protein STAU-1 0.022
bar-1 Protein BAR-1 0.022
larp-5 Protein LARP-5 0.022
dpy-21 Protein DPY-21 0.022
D1044.6 Protein D1044.6 0.022
Loading network...
Danio rerio
Name Description Probability Func Analog Organism
bcl2 B-cell leukemia/lymphoma 2 0.233
adrb2a adrenergic receptor, beta 2a 0.120
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.101
rtcd1 RNA terminal phosphate cyclase domain 1 0.064
zgc:73142 zgc:73142 0.055
tpm4 tropomyosin 4 0.055
atp2b1a ATPase, Ca++ transporting, plasma membrane 1a 0.053
nf1a neurofibromin 1a 0.052
cxcr4b chemokine (C-X-C motif), receptor 4b 0.047
pdlim1 PDZ and LIM domain 1 (elfin) 0.044
bida BH3 interacting domain death agonist 0.039
rtn1a reticulon 1a 0.035
mcl1b myeloid cell leukemia sequence 1b 0.032
hsp90a.2 heat shock protein 90-alpha 2 0.031
neb nebulin 0.030
hspa4a heat shock protein 4a 0.028
pak2a p21 (CDKN1A)-activated kinase 2a 0.025
pvalb1 parvalbumin 1 0.023
rras related RAS viral (r-ras) oncogene homolog 0.021
gclc glutamate-cysteine ligase, catalytic subunit 0.020
ahnak AHNAK nucleoprotein 0.020
cnn2 calponin 2 0.019
cebpa CCAAT/enhancer binding protein (C/EBP), alpha 0.019
si:dkey-228g21.4 si:dkey-228g21.4 0.019
dnaja1l DnaJ (Hsp40) homolog, subfamily A, member 1, like 0.019
msi1 musashi homolog 1 (Drosophila) 0.019
ywhai tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide 0.019
LOC100003330 melanocortin-2 receptor accessory protein 2-like 0.018
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.018
ncs1a neuronal calcium sensor 1a 0.017
yap1 Yes-associated protein 1 0.017
LOC559201 similar to Neuromedin-K receptor (NKR) (Neurokinin B receptor) (NK-3 receptor) (NK-3R) (Tachykinin receptor 3) 0.016
rps6ka3a ribosomal protein S6 kinase, polypeptide 3a 0.015
ccnb2 cyclin B2 0.015
LOC555482 tachykinin receptor 3-like 0.015
tert telomerase reverse transcriptase 0.014
cx55.5 connexin 55.5 0.014
crb2a crumbs homolog 2a 0.014
ilk integrin linked kinase 0.014
nme2b.2 non-metastatic cells 2b.2, protein (NM23B) expressed in 0.013
nf1b neurofibromin 1b 0.013
nt5e 5'-nucleotidase, ecto (CD73) 0.013
elmo1 engulfment and cell motility 1 (ced-12 homolog, C. elegans) 0.013
ndel1a nudE nuclear distribution gene E homolog like 1 (A. nidulans) A 0.012
gnaia guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a 0.012
prom1a prominin 1a 0.012
vim vimentin 0.012
cyp11b2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.012
whsc1 Wolf-Hirschhorn syndrome candidate 1 0.011
iqgap1 IQ motif containing GTPase activating protein 1 0.011
dbh dopamine beta hydroxylase 0.011
kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.011
LOC100004941 grpE protein homolog 2, mitochondrial-like 0.011
bcl2l1 bcl2-like 1 0.011
or115-10 odorant receptor, family F, subfamily 115, member 10 0.011
tie1 endothelium-specific receptor tyrosine kinase 1 0.010
ptgs2a prostaglandin-endoperoxide synthase 2a 0.010
rhoaa ras homolog gene family, member Aa 0.010
gnai2l guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like 0.010
mcamb melanoma cell adhesion molecule b 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pten CG5671 gene product from transcript CG5671-RB 0.765
Rheb CG1081 gene product from transcript CG1081-RA 0.701
Shaw Shaker cognate w 0.690
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.569
mbc myoblast city 0.514
rok Rho-kinase 0.473
Pkn Protein kinase related to protein kinase N 0.473
stg string 0.469
Wnk CG7177 gene product from transcript CG7177-RA 0.384
nwk nervous wreck 0.332
cenG1A centaurin gamma 1A 0.313
Khc Kinesin heavy chain 0.279
Gyc76C Guanylyl cyclase at 76C 0.255
Sbf SET domain binding factor 0.242
raps rapsynoid 0.239
rut rutabaga 0.232
Ank2 Ankyrin 2 0.229
Abi Abelson interacting protein 0.212
CycA Cyclin A 0.196
dos daughter of sevenless 0.194
drk downstream of receptor kinase 0.193
neur neuralized 0.192
cdm cadmus 0.191
Rbsn-5 Rabenosyn-5 0.190
stai stathmin 0.185
Sos Son of sevenless 0.183
Act57B Actin 57B 0.179
CG13253 CG13253 gene product from transcript CG13253-RB 0.176
dm diminutive 0.173
l(2)k16918 lethal (2) k16918 0.168
EcR Ecdysone receptor 0.160
pod1 CG4532 gene product from transcript CG4532-RF 0.157
Stat92E Signal-transducer and activator of transcription protein at 92E 0.156
Mtl Mig-2-like 0.154
yata CG1973 gene product from transcript CG1973-RA 0.151
Pak3 CG14895 gene product from transcript CG14895-RA 0.150
CG8334 CG8334 gene product from transcript CG8334-RA 0.150
trn tartan 0.145
ptc patched 0.144
wupA wings up A 0.141
Akt1 CG4006 gene product from transcript CG4006-RA 0.141
Dap160 Dynamin associated protein 160 0.137
plexB plexin B 0.133
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.127
Su(H) Suppressor of Hairless 0.125
oa2 octopamine receptor 2 0.124
Apc APC-like 0.124
N Notch 0.122
Mad Mothers against dpp 0.119
neuroligin CG13772 gene product from transcript CG13772-RA 0.114
CG18437 CG18437 gene product from transcript CG18437-RB 0.111
Ric Ras which interacts with Calmodulin 0.110
Hrs Hepatocyte growth factor regulated tyrosine kinase substrate 0.110
puc puckered 0.107
siz schizo 0.100
Tsc1 CG6147 gene product from transcript CG6147-RA 0.099
rl rolled 0.099
gcl germ cell-less 0.099
Rab6 Rab-protein 6 0.096
jeb jelly belly 0.096
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.096
Spf45 CG17540 gene product from transcript CG17540-RB 0.095
sax saxophone 0.092
NaCP60E Na channel protein 60E 0.090
Octbeta2R CG33976 gene product from transcript CG33976-RA 0.088
px plexus 0.088
Tbh Tyramine beta hydroxylase 0.084
Nmdar1 NMDA receptor 1 0.084
p120ctn Adherens junction protein p120 0.083
dnc dunce 0.080
car carnation 0.079
tutl turtle 0.077
ird1 immune response deficient 1 0.076
pbl pebble 0.076
CG32635 CG32635 gene product from transcript CG32635-RA 0.072
CG11033 CG11033 gene product from transcript CG11033-RB 0.072
trio CG18214 gene product from transcript CG18214-RA 0.071
RanBPM Ran-binding protein M 0.071
Pk61C Protein kinase 61C 0.070
Rip11 Rab11 interacting protein 0.070
slo slowpoke 0.070
CG1968 CG1968 gene product from transcript CG1968-RB 0.069
synj synaptojanin 0.069
sls sallimus 0.067
fd85E forkhead domain 85E 0.067
Sap47 Synapse-associated protein 47kD 0.067
Mlp84B Muscle LIM protein at 84B 0.066
cno canoe 0.066
G-oalpha47A G protein oalpha 47A 0.065
Tor Target of rapamycin 0.065
bbg big bang 0.064
Vps45 Vacuolar protein sorting 45 0.064
sima similar 0.064
hig hikaru genki 0.062
cher cheerio 0.062
mbt mushroom bodies tiny 0.062
Hr96 Hormone receptor-like in 96 0.062
Shc SHC-adaptor protein 0.062
dnr1 defense repressor 1 0.062
Gug Grunge 0.061
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.999
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.993
EXOSC3 exosome component 3 0.993
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.980
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.976
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.969
GSK3B glycogen synthase kinase 3 beta 0.967
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.951
PTK2 PTK2 protein tyrosine kinase 2 0.947
GRB2 growth factor receptor-bound protein 2 0.940
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.939
DNM1 dynamin 1 0.935
FGFR2 fibroblast growth factor receptor 2 0.917
NCKAP1 NCK-associated protein 1 0.914
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.911
EXOSC10 exosome component 10 0.907
BCR breakpoint cluster region 0.905
IL8 interleukin 8 0.900
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.888
S100A8 S100 calcium binding protein A8 0.883
CCR5 chemokine (C-C motif) receptor 5 0.874
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.868
S100A6 S100 calcium binding protein A6 0.864
EXOSC4 exosome component 4 0.859
EGFR epidermal growth factor receptor 0.859
NCF2 neutrophil cytosolic factor 2 0.857
DOCK1 dedicator of cytokinesis 1 0.854
SH3RF1 SH3 domain containing ring finger 1 0.847
RIN3 Ras and Rab interactor 3 0.836
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.835
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.833
FKBP4 FK506 binding protein 4, 59kDa 0.832
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.806
HRAS v-Ha-ras Harvey rat sarcoma viral oncogene homolog 0.796
SFN stratifin 0.787
BCAR1 breast cancer anti-estrogen resistance 1 0.774
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.747
SMN1 survival of motor neuron 1, telomeric 0.743
OCRL oculocerebrorenal syndrome of Lowe 0.737
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.728
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.716
PSEN1 presenilin 1 0.713
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.704
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.700
CXCL2 chemokine (C-X-C motif) ligand 2 0.682
GRB7 growth factor receptor-bound protein 7 0.680
S100A11 S100 calcium binding protein A11 0.678
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.676
CCL19 chemokine (C-C motif) ligand 19 0.676
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.666
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.662
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.651
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.650
SH3BP2 SH3-domain binding protein 2 0.647
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.617
DRD2 dopamine receptor D2 0.610
CCT3 chaperonin containing TCP1, subunit 3 (gamma) 0.606
CNKSR2 connector enhancer of kinase suppressor of Ras 2 0.591
CCL4 chemokine (C-C motif) ligand 4 0.590
CCL5 chemokine (C-C motif) ligand 5 0.588
RASSF5 Ras association (RalGDS/AF-6) domain family member 5 0.582
CXCL3 chemokine (C-X-C motif) ligand 3 0.582
CXCL9 chemokine (C-X-C motif) ligand 9 0.577
MT1A metallothionein 1A 0.576
S100A9 S100 calcium binding protein A9 0.570
ILK integrin-linked kinase 0.570
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 0.567
KIAA1683 KIAA1683 0.566
MARK3 MAP/microtubule affinity-regulating kinase 3 0.560
FGFR1 fibroblast growth factor receptor 1 0.551
IFNG interferon, gamma 0.543
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.534
THOC4 THO complex 4 0.532
CXCL10 chemokine (C-X-C motif) ligand 10 0.525
HTT huntingtin 0.523
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.513
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.512
FHL1 four and a half LIM domains 1 0.508
NCK2 NCK adaptor protein 2 0.502
PDE4DIP phosphodiesterase 4D interacting protein 0.495
TRAF1 TNF receptor-associated factor 1 0.494
S100A4 S100 calcium binding protein A4 0.493
PKN3 protein kinase N3 0.493
SLC9A3R1 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 0.492
HAP1 huntingtin-associated protein 1 0.489
CCL22 chemokine (C-C motif) ligand 22 0.484
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.484
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) 0.479
GDI2 GDP dissociation inhibitor 2 0.473
TMSB10 thymosin beta 10 0.461
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.456
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.455
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa 0.423
SH3RF3 SH3 domain containing ring finger 3 0.419
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.417
MYO9B myosin IXB 0.414
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.411
FMNL1 formin-like 1 0.410
ADRBK1 adrenergic, beta, receptor kinase 1 0.410
SH3KBP1 SH3-domain kinase binding protein 1 0.408
Loading network...
Rattus norvegicus
Name Description Probability Func Analog Organism
Adora2a adenosine A2a receptor 0.493
Arl1 ADP-ribosylation factor-like 1 0.358
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.299
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.273
Tagln transgelin 0.272
Akirin2 akirin 2 0.241
Utrn utrophin 0.226
Oxtr oxytocin receptor 0.221
Camk4 calcium/calmodulin-dependent protein kinase IV 0.220
Slc8a2 solute carrier family 8 (sodium/calcium exchanger), member 2 0.220
Flt1 FMS-related tyrosine kinase 1 0.212
Ppia peptidylprolyl isomerase A (cyclophilin A) 0.210
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.205
Anxa2 annexin A2 0.200
Ncan neurocan 0.199
Atp2a3 ATPase, Ca++ transporting, ubiquitous 0.189
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.185
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.183
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.180
Gucy1b3 guanylate cyclase 1, soluble, beta 3 0.177
Olr416 olfactory receptor 416 0.176
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.171
Cxcr5 chemokine (C-X-C motif) receptor 5 0.168
Prkch protein kinase C, eta 0.156
Pde1b phosphodiesterase 1B, calmodulin-dependent 0.154
Myo1c myosin IC 0.153
Pja2 praja 2, RING-H2 motif containing 0.146
Syt7 synaptotagmin VII 0.142
Csf1 colony stimulating factor 1 (macrophage) 0.137
Sirpa signal-regulatory protein alpha 0.137
Homer1 homer homolog 1 (Drosophila) 0.134
Adora1 adenosine A1 receptor 0.126
Fgf2 fibroblast growth factor 2 0.126
Lcp2 lymphocyte cytosolic protein 2 0.125
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.124
Copb1 coatomer protein complex, subunit beta 1 0.122
Ncr1 natural cytotoxicity triggering receptor 1 0.120
Timp3 TIMP metallopeptidase inhibitor 3 0.118
Pdyn prodynorphin 0.118
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.115
Cyss cystatin S 0.114
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.111
Vcsa1 variable coding sequence A1 0.111
Kitlg KIT ligand 0.108
Chrna6 cholinergic receptor, nicotinic, alpha 6 0.107
Gpr176 G protein-coupled receptor 176 0.107
Mapk9 mitogen-activated protein kinase 9 0.105
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.104
Picalm phosphatidylinositol binding clathrin assembly protein 0.103
Hpca hippocalcin 0.102
Pld2 phospholipase D2 0.102
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.096
Tnr tenascin R 0.096
Chrm4 cholinergic receptor, muscarinic 4 0.096
Prdm2 PR domain containing 2, with ZNF domain 0.095
Notch3 Notch homolog 3 (Drosophila) 0.095
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.094
Rab6a RAB6A, member RAS oncogene family 0.094
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.093
Lgals3 lectin, galactoside-binding, soluble, 3 0.092
Mgat5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.092
Strn striatin, calmodulin binding protein 0.092
Amph amphiphysin 0.092
Kcnab1 potassium voltage-gated channel, shaker-related subfamily, beta member 1 0.091
Hrh3 histamine receptor H3 0.091
Apc adenomatous polyposis coli 0.091
Crhbp corticotropin releasing hormone binding protein 0.089
Fam65a family with sequence similarity 65, member A 0.088
Nfasc neurofascin 0.087
Ppp2r2c protein phosphatase 2 (formerly 2A), regulatory subunit B, gamma isoform 0.085
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.085
Errfi1 ERBB receptor feedback inhibitor 1 0.084
Neurod2 neurogenic differentiation 2 0.084
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.084
S100a4 S100 calcium-binding protein A4 0.084
Mylk2 myosin light chain kinase 2 0.083
Cd4 Cd4 molecule 0.083
Gcm1 glial cells missing homolog 1 (Drosophila) 0.083
Eif3d eukaryotic translation initiation factor 3, subunit D 0.083
Slc25a5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.082
Vom1r93 vomeronasal 1 receptor 93 0.081
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.081
Grip2 glutamate receptor interacting protein 2 0.080
Ddr1 discoidin domain receptor tyrosine kinase 1 0.080
Klf6 Kruppel-like factor 6 0.079
Lphn2 latrophilin 2 0.078
Ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 0.078
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.078
Oprk1 opioid receptor, kappa 1 0.077
Bcl2l1 Bcl2-like 1 0.077
Cfp complement factor properdin 0.077
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.076
Defa-rs1 defensin alpha-related sequence 1 0.076
Gzmk granzyme K 0.075
Sept7 septin 7 0.075
Sh2d3c SH2 domain containing 3C 0.074
Slc12a3 solute carrier family 12 (sodium/chloride transporters), member 3 0.074
Camsap1l1 calmodulin regulated spectrin-associated protein 1-like 1 0.074
Klrb1a killer cell lectin-like receptor subfamily B, member 1A 0.074
Fgf7 fibroblast growth factor 7 0.074
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STE11 Ste11p 0.290
GYL1 Gyl1p 0.258
MKK1 Mkk1p 0.226
IRA1 Ira1p 0.225
GCD6 Gcd6p 0.217
STE5 Ste5p 0.137
RHO1 Rho1p 0.133
ROM2 Rom2p 0.128
SUI3 Sui3p 0.099
CDC24 Cdc24p 0.097
PKC1 Pkc1p 0.093
KEL1 Kel1p 0.077
BEM3 Bem3p 0.073
FAR1 Far1p 0.073
SPA2 Spa2p 0.068
MNN9 Mnn9p 0.062
VPS4 Vps4p 0.062
SSA4 Ssa4p 0.060
TOM1 Tom1p 0.058
SEC16 Sec16p 0.057
TUS1 Tus1p 0.052
VPS15 Vps15p 0.052
PEA2 Pea2p 0.051
STI1 Sti1p 0.051
SKT5 Skt5p 0.050
RGA2 Rga2p 0.049
ATG20 Atg20p 0.049
FYV8 Fyv8p 0.049
GCD7 Gcd7p 0.048
MDS3 Mds3p 0.047
COX4 Cox4p 0.046
YIL055C hypothetical protein 0.045
SOG2 Sog2p 0.045
DCD1 Dcd1p 0.045
NDE1 Nde1p 0.045
YIP3 Yip3p 0.044
CHS1 Chs1p 0.044
GZF3 Gzf3p 0.042
CUR1 Cur1p 0.041
PTP2 Ptp2p 0.040
YPT53 Ypt53p 0.040
SSK2 Ssk2p 0.040
NAT1 Nat1p 0.040
INP53 Inp53p 0.039
FIR1 Fir1p 0.039
KIC1 Kic1p 0.038
VTA1 Vta1p 0.038
BPT1 Bpt1p 0.037
FUS2 Fus2p 0.035
SWC7 Swc7p 0.035
GDS1 Gds1p 0.035
SLT2 Slt2p 0.034
FMS1 Fms1p 0.034
STB6 Stb6p 0.033
SAC7 Sac7p 0.033
YHR033W hypothetical protein 0.033
GPB2 Gpb2p 0.033
CLN3 Cln3p 0.033
HSV2 Hsv2p 0.033
AVO1 Avo1p 0.032
MBF1 Mbf1p 0.032
YGK3 Ygk3p 0.032
SUI2 Sui2p 0.032
MTC4 Mtc4p 0.031
YCR007C hypothetical protein 0.031
BTN2 Btn2p 0.031
BUD8 Bud8p 0.030
RPC31 Rpc31p 0.030
AST2 Ast2p 0.030
MOB2 Mob2p 0.030
YGL101W hypothetical protein 0.029
CMK2 Cmk2p 0.029
VPS13 Vps13p 0.029
SPF1 Spf1p 0.029
PEP5 Pep5p 0.029
EXO84 Exo84p 0.029
URA4 Ura4p 0.029
UFO1 Ufo1p 0.029
ENT2 Ent2p 0.029
YLR143W hypothetical protein 0.028
PMD1 Pmd1p 0.028
AKL1 Akl1p 0.028
MDH2 Mdh2p 0.028
MID1 Mid1p 0.028
HOR2 Hor2p 0.028
FIG4 Fig4p 0.028
BFR1 Bfr1p 0.028
YGR126W hypothetical protein 0.028
URA3 Ura3p 0.028
RGD1 Rgd1p 0.027
UBP5 Ubp5p 0.027
HIS6 His6p 0.027
SGT2 Sgt2p 0.027
SRP54 Srp54p 0.027
TPK3 Tpk3p 0.027
APM3 Apm3p 0.027
PPH21 Pph21p 0.027
RGD2 Rgd2p 0.026
INO2 Ino2p 0.026
PAR32 Par32p 0.026