The network for 'purine nucleotide catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine nucleotide catabolic process

The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

Rattus norvegicus
Name Description Probability Func Analog Organism
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.627
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.522
Arl1 ADP-ribosylation factor-like 1 0.464
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.444
Lman1 lectin, mannose-binding, 1 0.435
Tpm4 tropomyosin 4 0.427
Myl9 myosin, light chain 9, regulatory 0.420
Gria2 glutamate receptor, ionotropic, AMPA 2 0.384
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.289
Myadm myeloid-associated differentiation marker 0.276
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.258
Nae1 NEDD8 activating enzyme E1 subunit 1 0.251
Amph amphiphysin 0.216
Pfn1 profilin 1 0.213
Eif5 eukaryotic translation initiation factor 5 0.210
Csk c-src tyrosine kinase 0.209
Acta2 smooth muscle alpha-actin 0.204
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.202
Pja2 praja 2, RING-H2 motif containing 0.202
Gipc1 GIPC PDZ domain containing family, member 1 0.194
Cnn1 calponin 1, basic, smooth muscle 0.192
S100a6 S100 calcium binding protein A6 0.185
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.184
Casp3 caspase 3 0.179
Myo1c myosin IC 0.178
Shank2 SH3 and multiple ankyrin repeat domains 2 0.177
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.176
Anapc5 anaphase-promoting complex subunit 5 0.175
Myo1d myosin ID 0.175
Arpc1b actin related protein 2/3 complex, subunit 1B 0.170
Scarb1 scavenger receptor class B, member 1 0.168
Rab1b RAB1B, member RAS oncogene family 0.167
Emp1 epithelial membrane protein 1 0.166
Copb1 coatomer protein complex, subunit beta 1 0.165
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.164
Thop1 thimet oligopeptidase 1 0.164
Actg2 actin, gamma 2, smooth muscle, enteric 0.158
Cdk7 cyclin-dependent kinase 7 0.156
Arf1 ADP-ribosylation factor 1 0.154
Eef2 eukaryotic translation elongation factor 2 0.148
Pum1 pumilio homolog 1 (Drosophila) 0.146
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.145
Stip1 stress-induced phosphoprotein 1 0.143
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.143
Klf6 Kruppel-like factor 6 0.142
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.142
Rhoa ras homolog gene family, member A 0.141
Dnm1l dynamin 1-like 0.140
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.139
Cmklr1 chemokine-like receptor 1 0.139
Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) 0.138
Hspb1 heat shock protein 1 0.138
Ddr1 discoidin domain receptor tyrosine kinase 1 0.137
Tmed2 transmembrane emp24 domain trafficking protein 2 0.137
Flnb filamin, beta 0.136
Utrn utrophin 0.135
Vamp3 vesicle-associated membrane protein 3 0.133
Efhd2 EF-hand domain family, member D2 0.133
Hr hairless 0.133
Nckap1 NCK-associated protein 1 0.132
Myh11 myosin, heavy chain 11, smooth muscle 0.131
Actg1 actin, gamma 1 0.130
S100a11 S100 calcium binding protein A11 (calizzarin) 0.130
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.130
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.129
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.129
Elk3 ELK3, ETS-domain protein 0.128
Prkch protein kinase C, eta 0.125
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.125
Klf4 Kruppel-like factor 4 (gut) 0.125
Tgfbr2 transforming growth factor, beta receptor II 0.124
Rala v-ral simian leukemia viral oncogene homolog A (ras related) 0.124
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.123
Actn2 actinin alpha 2 0.122
Cyth3 cytohesin 3 0.122
Barhl2 BarH-like homeobox 2 0.121
Robo2 roundabout homolog 2 (Drosophila) 0.120
Atp5a1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.120
Irf5 interferon regulatory factor 5 0.117
Errfi1 ERBB receptor feedback inhibitor 1 0.117
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.117
Zfp260 zinc finger protein 260 0.114
Arpc2 actin related protein 2/3 complex, subunit 2 0.112
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.112
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.112
Acox2 acyl-Coenzyme A oxidase 2, branched chain 0.111
Tagln transgelin 0.110
Cdc42bpb CDC42 binding protein kinase beta (DMPK-like) 0.109
Cd37 CD37 molecule 0.108
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.107
Tfpi tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.106
Syngr2 synaptogyrin 2 0.106
S100a10 S100 calcium binding protein A10 0.105
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.105
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.105
Chrm3 cholinergic receptor, muscarinic 3 0.105
Atp4b ATPase, H+/K+ exchanging, beta polypeptide 0.105
Anxa2 annexin A2 0.104
S1pr2 sphingosine-1-phosphate receptor 2 0.103
Pdcd6 programmed cell death 6 0.103
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.934
sem-5 Protein SEM-5 0.666
pkg-1 Protein PKG-1 0.582
miro-1 Protein MIRO-1 0.525
D1081.8 Protein D1081.8 0.480
unc-45 Protein UNC-45 0.420
T23F11.1 Protein T23F11.1 0.411
gpr-1 Protein GPR-1 0.405
chc-1 Protein CHC-1 0.379
let-60 Protein LET-60 0.346
ced-10 Protein CED-10 0.316
CELE_F47G4.4 Protein F47G4.4 0.307
gei-18 Protein GEI-18 0.277
gei-4 Protein GEI-4 0.252
ret-1 Protein RET-1 0.250
CELE_F29C4.2 Protein F29C4.2 0.242
glh-4 Protein GLH-4 0.239
abts-1 Protein ABTS-1 0.234
glo-4 Protein GLO-4 0.221
prp-8 Protein PRP-8 0.216
spd-2 Protein SPD-2 0.215
smc-4 Protein SMC-4 0.192
plc-3 Protein PLC-3 0.191
atp-2 Protein ATP-2 0.173
kin-2 Protein KIN-2 0.170
hif-1 Protein HIF-1 0.170
mbk-1 Protein MBK-1 0.165
rod-1 Protein ROD-1 0.163
bmk-1 Protein BMK-1 0.157
R53.4 Protein R53.4 0.156
cah-6 Protein CAH-6 0.156
F33E11.3 Protein F33E11.3 0.156
dpf-3 Protein DPF-3 0.153
rgl-1 Protein RGL-1 0.153
pdl-1 Protein PDL-1 0.149
sas-4 Protein SAS-4 0.149
rhgf-2 Protein RHGF-2 0.148
rme-4 Protein RME-4 0.143
ykt-6 Protein YKT-6 0.142
cyc-1 Protein CYC-1 0.142
frm-7 Protein FRM-7 0.142
egl-13 Protein EGL-13 0.140
crt-1 Protein CRT-1 0.140
mcm-2 Protein MCM-2 0.140
mau-2 Protein MAU-2 0.139
zen-4 Protein ZEN-4 0.137
CELE_W07A8.2 Protein W07A8.2 0.137
csr-1 Protein CSR-1 0.136
etr-1 Protein ETR-1 0.136
alx-1 Protein ALX-1 0.135
dnc-2 Protein DNC-2 0.134
cmd-1 Protein CMD-1 0.133
gpb-1 Protein GPB-1 0.133
pbrm-1 Protein PBRM-1 0.132
B0495.2 Protein B0495.2 0.131
egl-9 Protein EGL-9 0.131
daf-19 Protein DAF-19 0.129
inft-2 Protein INFT-2 0.126
eef-1A.2 Protein EEF-1A.2 0.126
C34E10.8 Protein C34E10.8 0.124
pqn-85 Protein PQN-85 0.121
C30G12.6 Protein C30G12.6 0.120
lfi-1 Protein LFI-1 0.118
coh-3 Protein COH-3 0.115
aspm-1 Protein ASPM-1 0.114
imb-1 Protein IMB-1 0.114
tag-123 Protein TAG-123 0.114
cyk-4 Protein CYK-4 0.114
hsp-16.41 Protein HSP-16.41 0.114
C53C9.2 Protein C53C9.2 0.114
sli-1 Protein SLI-1 0.112
unc-71 Protein UNC-71 0.111
cdc-42 Protein CDC-42 0.111
unc-2 Protein UNC-2 0.108
hsp-16.1 Protein HSP-16.1 0.108
idhb-1 Protein IDHB-1 0.107
gpr-2 Protein GPR-2 0.107
mei-1 Protein MEI-1 0.105
Y44E3A.6 Protein Y44E3A.6 0.105
CELE_Y60A3A.9 Protein Y60A3A.9 0.104
F23H11.5 Protein F23H11.5 0.104
egl-15 Protein EGL-15 0.104
F35G2.1 Protein F35G2.1 0.103
csnk-1 Protein CSNK-1 0.102
rab-5 Protein RAB-5 0.102
snf-1 Protein SNF-1 0.101
F28C6.4 Protein F28C6.4 0.100
dnj-16 Protein DNJ-16 0.100
CELE_C38D4.1 Protein C38D4.1 0.098
ric-8 Protein RIC-8 0.097
mai-2 Protein MAI-2 0.097
lev-11 Protein LEV-11 0.096
trr-1 Protein TRR-1 0.096
stim-1 Protein STIM-1 0.094
CELE_W03F9.10 Protein W03F9.10 0.093
F44E5.1 Protein F44E5.1 0.092
R04F11.2 Protein R04F11.2 0.092
itr-1 Protein ITR-1 0.092
fncm-1 Protein FNCM-1 0.091
nmy-2 Protein NMY-2 0.090
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Danio rerio
Name Description Probability Func Analog Organism
atp6v0ca ATPase, H+ transporting, lysosomal, V0 subunit c, a 0.021
atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.019
ache acetylcholinesterase 0.017
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.016
bactin2 bactin2 0.015
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.014
bms1l BMS1-like, ribosome assembly protein (yeast) 0.014
tnni2a.4 troponin I, skeletal, fast 2a.4 0.012
ryr3 ryanodine receptor 3 0.011
bida BH3 interacting domain death agonist 0.010
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.996
Rheb CG1081 gene product from transcript CG1081-RA 0.894
drpr draper 0.862
Khc Kinesin heavy chain 0.762
Pten CG5671 gene product from transcript CG5671-RB 0.731
Chc Clathrin heavy chain 0.723
Stat92E Signal-transducer and activator of transcription protein at 92E 0.688
Myo31DF Myosin 31DF 0.670
shi shibire 0.603
Rac1 CG2248 gene product from transcript CG2248-RA 0.592
mbc myoblast city 0.581
trio CG18214 gene product from transcript CG18214-RA 0.541
gfA giant fibre A 0.540
Fak56D Focal Adhesion Kinase 0.538
Wnk CG7177 gene product from transcript CG7177-RA 0.532
Uba1 Ubiquitin activating enzyme 1 0.509
didum dilute class unconventional myosin 0.507
rictor rapamycin-insensitive companion of Tor 0.500
CG6509 CG6509 gene product from transcript CG6509-RB 0.494
Cip4 CG15015 gene product from transcript CG15015-RA 0.491
stai stathmin 0.477
Jra Jun-related antigen 0.477
Mad Mothers against dpp 0.459
CG8155 CG8155 gene product from transcript CG8155-RA 0.458
Eph Eph receptor tyrosine kinase 0.451
Moe Moesin 0.404
Apc APC-like 0.403
Pkn Protein kinase related to protein kinase N 0.391
TER94 CG2331 gene product from transcript CG2331-RA 0.389
mys myospheroid 0.388
tsr twinstar 0.383
Rab7 Rab-protein 7 0.373
LanA Laminin A 0.369
CG3004 CG3004 gene product from transcript CG3004-RA 0.368
insc inscuteable 0.365
S6k RPS6-p70-protein kinase 0.347
dys dysfusion 0.335
Pk61C Protein kinase 61C 0.332
Dap160 Dynamin associated protein 160 0.331
Dhc64C Dynein heavy chain 64C 0.331
WASp CG1520 gene product from transcript CG1520-RA 0.327
Rab5 Rab-protein 5 0.324
pod1 CG4532 gene product from transcript CG4532-RF 0.324
flw flapwing 0.321
wit wishful thinking 0.317
Caps Calcium activated protein for secretion 0.315
CG32772 CG32772 gene product from transcript CG32772-RC 0.311
cenG1A centaurin gamma 1A 0.310
puc puckered 0.300
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.294
wapl wings apart-like 0.294
CG7998 CG7998 gene product from transcript CG7998-RA 0.281
ninaC neither inactivation nor afterpotential C 0.280
dock dreadlocks 0.280
HLH106 Helix loop helix protein 106 0.279
Snap25 Synapse protein 25 0.275
Gie novel GTPase indispensable for equal segregation of chromosomes 0.270
Ced-12 CG5336 gene product from transcript CG5336-RA 0.266
Mer Merlin 0.264
Rab2 Rab-protein 2 0.261
NaCP60E Na channel protein 60E 0.257
E(z) Enhancer of zeste 0.256
Ephrin CG1862 gene product from transcript CG1862-RA 0.252
rut rutabaga 0.246
baz bazooka 0.241
Rme-8 Receptor mediated endocytosis 8 0.239
Pak PAK-kinase 0.236
cindr CIN85 and CD2AP orthologue 0.235
mbt mushroom bodies tiny 0.233
wupA wings up A 0.218
PTP-ER Protein tyrosine phosphatase-ERK/Enhancer of Ras1 0.218
ik2 IkappaB kinase-like 2 0.217
Rbsn-5 Rabenosyn-5 0.214
RhoBTB CG5701 gene product from transcript CG5701-RA 0.213
ninaE neither inactivation nor afterpotential E 0.213
sun stunted 0.213
unc-104 CG8566 gene product from transcript CG8566-RB 0.207
pbl pebble 0.207
coro CG9446 gene product from transcript CG9446-RC 0.201
trp transient receptor potential 0.200
rhea CG6831 gene product from transcript CG6831-RA 0.195
ecd ecdysoneless 0.194
Smg1 CG32743 gene product from transcript CG32743-RA 0.194
Gyc-89Da Guanylyl cyclase at 89Da 0.190
par-1 CG8201 gene product from transcript CG8201-RA 0.190
CG11376 CG11376 gene product from transcript CG11376-RA 0.189
bor belphegor 0.182
Act5C Actin 5C 0.179
loco locomotion defects 0.177
kibra kibra ortholog 0.177
Eip63E Ecdysone-induced protein 63E 0.172
cpa capping protein alpha 0.172
gcl germ cell-less 0.171
egl egalitarian 0.170
CG1021 CG1021 gene product from transcript CG1021-RE 0.169
CG2991 CG2991 gene product from transcript CG2991-RA 0.164
ck crinkled 0.164
rok Rho-kinase 0.163
G-ialpha65A G protein alphai subunit 65A 0.160
ken ken and barbie 0.155
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Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.998
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.998
RAB5A RAB5A, member RAS oncogene family 0.996
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.996
ARRB1 arrestin, beta 1 0.995
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.995
OCRL oculocerebrorenal syndrome of Lowe 0.994
EGFR epidermal growth factor receptor 0.994
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.992
GRB2 growth factor receptor-bound protein 2 0.992
SH3KBP1 SH3-domain kinase binding protein 1 0.991
SFN stratifin 0.990
DNM2 dynamin 2 0.988
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.979
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.978
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.972
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.970
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.970
PTK2 PTK2 protein tyrosine kinase 2 0.967
FGFR2 fibroblast growth factor receptor 2 0.965
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.964
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.955
DNM1 dynamin 1 0.954
ITSN1 intersectin 1 (SH3 domain protein) 0.954
SNX9 sorting nexin 9 0.954
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.949
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.946
ZYX zyxin 0.941
CDK7 cyclin-dependent kinase 7 0.939
NCK2 NCK adaptor protein 2 0.938
TOR1A torsin family 1, member A (torsin A) 0.932
EEA1 early endosome antigen 1 0.931
TNNC1 troponin C type 1 (slow) 0.922
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.916
PLCG1 phospholipase C, gamma 1 0.916
TPM1 tropomyosin 1 (alpha) 0.912
SMAD2 SMAD family member 2 0.911
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.911
ERBB2IP erbb2 interacting protein 0.901
RAB1A RAB1A, member RAS oncogene family 0.897
STIP1 stress-induced-phosphoprotein 1 0.892
S100B S100 calcium binding protein B 0.884
NCAPG non-SMC condensin I complex, subunit G 0.867
ERCC3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing) 0.856
RIN3 Ras and Rab interactor 3 0.851
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.847
ARRB2 arrestin, beta 2 0.842
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.839
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.839
BCAR1 breast cancer anti-estrogen resistance 1 0.829
MYO9B myosin IXB 0.824
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.823
FASLG Fas ligand (TNF superfamily, member 6) 0.813
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.804
RFC1 replication factor C (activator 1) 1, 145kDa 0.804
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.803
PLEC plectin 0.794
S100A6 S100 calcium binding protein A6 0.789
H2AFX H2A histone family, member X 0.784
TMSB4X thymosin beta 4, X-linked 0.781
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.776
CCNH cyclin H 0.775
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.774
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.774
UQCRC2 ubiquinol-cytochrome c reductase core protein II 0.768
FNBP1 formin binding protein 1 0.766
ABI1 abl-interactor 1 0.763
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.761
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) 0.761
VAMP7 vesicle-associated membrane protein 7 0.749
ILK integrin-linked kinase 0.748
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.746
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.744
TRAF5 TNF receptor-associated factor 5 0.743
S100A1 S100 calcium binding protein A1 0.739
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.734
ZMYND11 zinc finger, MYND-type containing 11 0.733
S100A8 S100 calcium binding protein A8 0.727
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.726
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.723
FGFR1 fibroblast growth factor receptor 1 0.722
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.715
BCL2L1 BCL2-like 1 0.713
TJP2 tight junction protein 2 (zona occludens 2) 0.712
TRAF2 TNF receptor-associated factor 2 0.709
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 0.704
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.702
HSPH1 heat shock 105kDa/110kDa protein 1 0.701
SH3BP2 SH3-domain binding protein 2 0.696
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.695
BLM Bloom syndrome, RecQ helicase-like 0.694
SMN1 survival of motor neuron 1, telomeric 0.693
STAT5A signal transducer and activator of transcription 5A 0.684
LIMS1 LIM and senescent cell antigen-like domains 1 0.679
ANXA7 annexin A7 0.673
HSPA1B heat shock 70kDa protein 1B 0.671
RABGAP1 RAB GTPase activating protein 1 0.663
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.656
CCR5 chemokine (C-C motif) receptor 5 0.653
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Epha4 Eph receptor A4 0.979
Braf Braf transforming gene 0.935
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.926
Bcl2 B-cell leukemia/lymphoma 2 0.921
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.911
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.890
Arrb2 arrestin, beta 2 0.873
Ntf3 neurotrophin 3 0.854
Pxn paxillin 0.854
Dnm1 dynamin 1 0.844
Plcg1 phospholipase C, gamma 1 0.832
Plxna1 plexin A1 0.818
Kl klotho 0.816
Ephb2 Eph receptor B2 0.807
Rac1 RAS-related C3 botulinum substrate 1 0.807
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.806
Akt1 thymoma viral proto-oncogene 1 0.748
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.734
Ctnnb1 catenin (cadherin associated protein), beta 1 0.734
Adrb1 adrenergic receptor, beta 1 0.721
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.711
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.706
Grb2 growth factor receptor bound protein 2 0.700
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.699
Bax BCL2-associated X protein 0.697
Lrrk2 leucine-rich repeat kinase 2 0.695
Nf1 neurofibromatosis 1 0.678
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.677
Cttn cortactin 0.676
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.672
Efnb2 ephrin B2 0.669
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.664
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.625
Dock1 dedicator of cytokinesis 1 0.623
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.610
Shc3 src homology 2 domain-containing transforming protein C3 0.606
Ptk2 PTK2 protein tyrosine kinase 2 0.604
Clstn1 calsyntenin 1 0.604
Eea1 early endosome antigen 1 0.585
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.584
Rasgrp2 RAS, guanyl releasing protein 2 0.583
Tnnt3 troponin T3, skeletal, fast 0.576
T brachyury 0.574
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.564
Src Rous sarcoma oncogene 0.545
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.544
Vapa vesicle-associated membrane protein, associated protein A 0.535
Ly6h lymphocyte antigen 6 complex, locus H 0.528
Ret ret proto-oncogene 0.527
Brca2 breast cancer 2 0.525
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.524
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 0.518
Srsf9 serine/arginine-rich splicing factor 9 0.508
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.506
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.492
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.490
L1cam L1 cell adhesion molecule 0.477
Nsf N-ethylmaleimide sensitive fusion protein 0.475
Spnb2 spectrin beta 2 0.470
Tnni2 troponin I, skeletal, fast 2 0.465
Chmp2b chromatin modifying protein 2B 0.463
Prkcd protein kinase C, delta 0.461
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.460
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.460
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.458
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.456
Syn2 synapsin II 0.453
Plekho2 pleckstrin homology domain containing, family O member 2 0.451
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.450
Sult4a1 sulfotransferase family 4A, member 1 0.438
Rtkn rhotekin 0.429
Pnpla2 patatin-like phospholipase domain containing 2 0.426
Tubb2c tubulin, beta 2C 0.425
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.424
Cct3 chaperonin containing Tcp1, subunit 3 (gamma) 0.424
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.420
Sh2b3 SH2B adaptor protein 3 0.418
Ltb lymphotoxin B 0.417
Tgfbr1 transforming growth factor, beta receptor I 0.412
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.409
Selplg selectin, platelet (p-selectin) ligand 0.405
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.403
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.399
Arhgef2 rho/rac guanine nucleotide exchange factor (GEF) 2 0.395
Cdk14 cyclin-dependent kinase 14 0.391
Tgtp2 T-cell specific GTPase 2 0.389
Fmnl1 formin-like 1 0.388
Abcg5 ATP-binding cassette, sub-family G (WHITE), member 5 0.381
Adarb1 adenosine deaminase, RNA-specific, B1 0.380
Plxnd1 plexin D1 0.378
Smc1a structural maintenance of chromosomes 1A 0.377
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.373
Ulk2 Unc-51 like kinase 2 (C. elegans) 0.373
Tnfrsf4 tumor necrosis factor receptor superfamily, member 4 0.372
Bdnf brain derived neurotrophic factor 0.364
Plxnb1 plexin B1 0.363
Rasgrp1 RAS guanyl releasing protein 1 0.363
Abcb1a ATP-binding cassette, sub-family B (MDR/TAP), member 1A 0.360
Nphs2 nephrosis 2 homolog, podocin (human) 0.359
Tff1 trefoil factor 1 0.355
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RHO1 Rho1p 0.800
YPT52 Ypt52p 0.636
SSL1 Ssl1p 0.572
TFB4 Tfb4p 0.503
GDI1 Gdi1p 0.487
STE5 Ste5p 0.468
STE11 Ste11p 0.436
YPT1 Ypt1p 0.410
SEC13 Sec13p 0.394
ROM2 Rom2p 0.370
STI1 Sti1p 0.365
YPT31 Ypt31p 0.357
FKH1 Fkh1p 0.339
ISW1 Isw1p 0.337
ITC1 Itc1p 0.310
AVO1 Avo1p 0.302
STE4 Ste4p 0.301
SUI3 Sui3p 0.298
MDS3 Mds3p 0.290
MYO3 Myo3p 0.278
RPT6 Rpt6p 0.260
KIN28 Kin28p 0.259
BEM3 Bem3p 0.256
KEL1 Kel1p 0.233
NYV1 Nyv1p 0.228
YPT10 Ypt10p 0.224
TRS65 Trs65p 0.222
MED1 Med1p 0.216
YDJ1 Ydj1p 0.216
SEC16 Sec16p 0.208
ACK1 Ack1p 0.194
RPT3 Rpt3p 0.181
TFB5 Tfb5p 0.175
INP53 Inp53p 0.175
MKK1 Mkk1p 0.174
RFC1 Rfc1p 0.173
YIP3 Yip3p 0.170
PEX1 Pex1p 0.169
SWI1 Swi1p 0.166
VPS4 Vps4p 0.164
IRA1 Ira1p 0.157
TOM1 Tom1p 0.156
BEM4 Bem4p 0.155
CCL1 Ccl1p 0.155
SSA1 Ssa1p 0.150
SEC3 Sec3p 0.145
RVB1 Rvb1p 0.142
SAC6 Sac6p 0.141
PKC1 Pkc1p 0.138
PEX5 Pex5p 0.135
SIS1 Sis1p 0.134
YPT53 Ypt53p 0.133
HUL4 Hul4p 0.133
MOB2 Mob2p 0.132
YPT7 Ypt7p 0.127
RPN3 Rpn3p 0.126
STE20 Ste20p 0.126
CDC24 Cdc24p 0.125
PEP5 Pep5p 0.123
PKH2 Pkh2p 0.123
KOG1 Kog1p 0.123
POL30 Pol30p 0.120
MOT1 Mot1p 0.118
PEX15 Pex15p 0.115
BOI1 Boi1p 0.114
CDC50 Cdc50p 0.114
SIN4 Sin4p 0.113
TFB3 Tfb3p 0.112
MKT1 Mkt1p 0.110
VPS36 Vps36p 0.109
HIR3 Hir3p 0.109
NOP7 Nop7p 0.108
VPS15 Vps15p 0.107
TFB1 Tfb1p 0.106
DOP1 Dop1p 0.106
IOC3 Ioc3p 0.106
MYO5 Myo5p 0.106
SEC24 Sec24p 0.105
VPS13 Vps13p 0.105
EDE1 Ede1p 0.104
CHC1 Chc1p 0.103
TRS20 Trs20p 0.103
POM152 Pom152p 0.102
RTT106 Rtt106p 0.101
RAD52 Rad52p 0.100
INO80 Ino80p 0.100
YGR237C hypothetical protein 0.100
HTA2 Hta2p 0.099
ORC2 Orc2p 0.099
MYO4 Myo4p 0.098
SNU114 Snu114p 0.097
SAC7 Sac7p 0.095
YDR026C hypothetical protein 0.095
KEM1 Kem1p 0.094
PXA1 Pxa1p 0.094
PMC1 Pmc1p 0.093
GCD11 Gcd11p 0.090
PRD1 Prd1p 0.089
SEC21 Sec21p 0.089
DNF3 Dnf3p 0.089