The network for 'purine ribonucleoside catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine ribonucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.

Rattus norvegicus
Name Description Probability Func Analog Organism
Rhoa ras homolog gene family, member A 0.584
Pja2 praja 2, RING-H2 motif containing 0.512
Hk1 hexokinase 1 0.490
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.366
Acta2 smooth muscle alpha-actin 0.359
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.352
Anxa2 annexin A2 0.317
Itgb1 integrin, beta 1 0.309
Eif5 eukaryotic translation initiation factor 5 0.287
Gria2 glutamate receptor, ionotropic, AMPA 2 0.276
Arl1 ADP-ribosylation factor-like 1 0.276
Amph amphiphysin 0.268
Myadm myeloid-associated differentiation marker 0.267
Pls3 plastin 3 (T-isoform) 0.264
S100a6 S100 calcium binding protein A6 0.263
Pcnxl3 pecanex-like 3 (Drosophila) 0.238
Cyth3 cytohesin 3 0.234
Stxbp5 syntaxin binding protein 5 (tomosyn) 0.222
Vim vimentin 0.216
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.212
Fgfr1 Fibroblast growth factor receptor 1 0.212
Sh3gl2 SH3-domain GRB2-like 2 0.210
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.202
Tagln2 transgelin 2 0.202
Mapk3 mitogen activated protein kinase 3 0.199
S100a10 S100 calcium binding protein A10 0.198
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.197
Stxbp1 syntaxin binding protein 1 0.197
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.196
Epas1 endothelial PAS domain protein 1 0.188
Nptn neuroplastin 0.186
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.182
Lman1 lectin, mannose-binding, 1 0.176
Atp2a1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 0.176
Scarb1 scavenger receptor class B, member 1 0.175
Cmklr1 chemokine-like receptor 1 0.175
Homer1 homer homolog 1 (Drosophila) 0.171
Dnm1l dynamin 1-like 0.161
Pctk1 PCTAIRE protein kinase 1 0.152
Akap1 A kinase (PRKA) anchor protein 1 0.148
St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 0.147
Sox17 SRY (sex determining region Y)-box 17 0.145
Camk4 calcium/calmodulin-dependent protein kinase IV 0.142
Gnai3 guanine nucleotide binding protein (G protein), alpha inhibiting 3 0.139
Sel1l sel-1 suppressor of lin-12-like (C. elegans) 0.139
Pik3r2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.139
Mapk9 mitogen-activated protein kinase 9 0.139
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.138
Anapc5 anaphase-promoting complex subunit 5 0.138
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.135
Tpm4 tropomyosin 4 0.134
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.134
Dnajc5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.133
Myo1b myosin Ib 0.130
Hspb1 heat shock protein 1 0.130
Dlg3 discs, large homolog 3 (Drosophila) 0.130
Tgfbr2 transforming growth factor, beta receptor II 0.129
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.128
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.127
Casp3 caspase 3 0.126
Jtb jumping translocation breakpoint 0.125
Csnk2b casein kinase 2, beta polypeptide 0.125
Mapk8ip1 mitogen-activated protein kinase 8 interacting protein 1 0.124
Pdcl3 phosducin-like 3 0.123
Pfn1 profilin 1 0.122
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 0.122
Agap3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 0.121
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.119
Kcnc2 potassium voltage gated channel, Shaw-related subfamily, member 2 0.116
Wipf3 WAS/WASL interacting protein family, member 3 0.116
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.115
Mgat5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.114
Accn1 amiloride-sensitive cation channel 1, neuronal 0.113
Adora1 adenosine A1 receptor 0.111
Cdc42 cell division cycle 42 (GTP binding protein) 0.111
Rhoc ras homolog gene family, member C 0.110
Arpc1b actin related protein 2/3 complex, subunit 1B 0.110
Apoa1 apolipoprotein A-I 0.108
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.108
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.107
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.106
Ccr5 chemokine (C-C motif) receptor 5 0.106
Tpm2 tropomyosin 2, beta 0.105
Utrn utrophin 0.104
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.104
Rab1 RAB1, member RAS oncogene family 0.103
Map2 microtubule-associated protein 2 0.102
Btk Bruton agammaglobulinemia tyrosine kinase 0.102
Dnm2 dynamin 2 0.100
Lmna lamin A 0.100
Abi3 ABI family, member 3 0.099
Irf5 interferon regulatory factor 5 0.099
LOC301128 similar to jumonji domain containing 2B 0.098
Chrm1 cholinergic receptor, muscarinic 1 0.098
Mapk1 mitogen activated protein kinase 1 0.097
Nckap1 NCK-associated protein 1 0.096
Arhgap4 Rho GTPase activating protein 4 0.096
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.096
Cyth1 cytohesin 1 0.095
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.095
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
goa-1 Protein GOA-1 0.771
dpf-3 Protein DPF-3 0.411
pkg-1 Protein PKG-1 0.391
rpl-11.1 Protein RPL-11.1 0.372
sem-5 Protein SEM-5 0.362
unc-54 Protein UNC-54 0.354
kin-2 Protein KIN-2 0.321
D1081.8 Protein D1081.8 0.292
frm-7 Protein FRM-7 0.280
apg-1 Protein APG-1 0.275
CELE_F29C4.2 Protein F29C4.2 0.254
coh-3 Protein COH-3 0.251
unc-45 Protein UNC-45 0.238
C53C9.2 Protein C53C9.2 0.232
F44E5.1 Protein F44E5.1 0.222
prg-1 Protein PRG-1 0.214
alx-1 Protein ALX-1 0.209
mig-6 Protein MIG-6 0.191
gei-18 Protein GEI-18 0.189
snf-1 Protein SNF-1 0.185
chc-1 Protein CHC-1 0.169
lin-10 Protein LIN-10 0.163
egl-8 Protein EGL-8 0.156
cmd-1 Protein CMD-1 0.155
hsp-16.2 Protein HSP-16.2 0.154
lfi-1 Protein LFI-1 0.152
R53.4 Protein R53.4 0.148
ret-1 Protein RET-1 0.148
CELE_W03F9.10 Protein W03F9.10 0.147
lin-5 Protein LIN-5 0.144
aspm-1 Protein ASPM-1 0.141
sas-4 Protein SAS-4 0.141
vha-14 Protein VHA-14 0.138
imb-1 Protein IMB-1 0.136
ced-10 Protein CED-10 0.135
rgl-1 Protein RGL-1 0.130
eat-20 Protein EAT-20 0.130
F29B9.8 Protein F29B9.8 0.125
F22D3.2 Protein F22D3.2 0.125
prp-8 Protein PRP-8 0.124
coq-8 Protein COQ-8 0.123
mau-2 Protein MAU-2 0.123
miro-1 Protein MIRO-1 0.123
atp-2 Protein ATP-2 0.121
plc-3 Protein PLC-3 0.121
cyk-4 Protein CYK-4 0.121
CELE_Y57A10A.13 Protein Y57A10A.13 0.120
larp-5 Protein LARP-5 0.119
pptr-2 Protein PPTR-2 0.119
csnk-1 Protein CSNK-1 0.118
unc-73 Protein UNC-73 0.118
F54D12.4 Protein F54D12.4 0.116
let-60 Protein LET-60 0.116
pbs-1 Protein PBS-1 0.114
F58F12.1 Protein F58F12.1 0.114
sax-3 Protein SAX-3 0.113
rhgf-2 Protein RHGF-2 0.112
bmk-1 Protein BMK-1 0.111
div-1 Protein DIV-1 0.110
unc-15 Protein UNC-15 0.108
skp-1 Protein SKP-1 0.107
zyg-9 Protein ZYG-9 0.107
abts-1 Protein ABTS-1 0.107
spd-2 Protein SPD-2 0.106
clk-2 Protein CLK-2 0.106
F39H12.3 Protein F39H12.3 0.105
T04F8.6 Protein T04F8.6 0.104
kin-25 Protein KIN-25 0.104
cyc-1 Protein CYC-1 0.104
unc-71 Protein UNC-71 0.104
csr-1 Protein CSR-1 0.103
Y15E3A.4 Protein Y15E3A.4 0.103
etr-1 Protein ETR-1 0.102
B0495.2 Protein B0495.2 0.102
vab-10 Protein VAB-10 0.100
aos-1 Protein AOS-1 0.100
gpb-1 Protein GPB-1 0.100
nhr-45 Protein NHR-45 0.100
rfc-1 Protein RFC-1 0.098
gpr-2 Protein GPR-2 0.098
mig-2 Protein MIG-2 0.096
athp-2 Protein ATHP-2 0.096
F09A5.4 Protein F09A5.4 0.094
gei-4 Protein GEI-4 0.091
lag-1 Protein LAG-1 0.090
CELE_Y48A5A.1 Protein Y48A5A.1 0.090
CELE_F25B4.5 Protein F25B4.5 0.089
npp-15 Protein NPP-15 0.088
tag-341 Protein TAG-341 0.087
T23F11.1 Protein T23F11.1 0.086
sma-6 Protein SMA-6 0.085
klp-15 Protein KLP-15 0.085
mcm-6 Protein MCM-6 0.084
ncs-2 Protein NCS-2 0.084
R10H10.7 Protein R10H10.7 0.083
nst-1 Protein NST-1 0.083
gen-1 Protein GEN-1 0.083
ucr-2.3 Protein UCR-2.3 0.083
tars-1 Protein TARS-1 0.082
rab-5 Protein RAB-5 0.082
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Danio rerio
Name Description Probability Func Analog Organism
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.016
tnni2a.4 troponin I, skeletal, fast 2a.4 0.013
cct5 chaperonin containing TCP1, subunit 5 (epsilon) 0.013
smyhc2 slow myosin heavy chain 2 0.013
bida BH3 interacting domain death agonist 0.011
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.010
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.980
Moe Moesin 0.820
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.750
Rac1 CG2248 gene product from transcript CG2248-RA 0.717
Myo31DF Myosin 31DF 0.707
chic chickadee 0.687
Dhc64C Dynein heavy chain 64C 0.681
G-oalpha47A G protein oalpha 47A 0.648
sgg shaggy 0.607
Rheb CG1081 gene product from transcript CG1081-RA 0.589
DAAM Dishevelled Associated Activator of Morphogenesis 0.531
Pak3 CG14895 gene product from transcript CG14895-RA 0.525
Pten CG5671 gene product from transcript CG5671-RB 0.517
loco locomotion defects 0.474
sun stunted 0.427
Khc Kinesin heavy chain 0.420
Pkn Protein kinase related to protein kinase N 0.420
arm armadillo 0.406
drpr draper 0.403
Syx7 Syntaxin 7 0.375
Wnk CG7177 gene product from transcript CG7177-RA 0.370
rictor rapamycin-insensitive companion of Tor 0.369
mbt mushroom bodies tiny 0.367
flw flapwing 0.346
Ras85D Ras oncogene at 85D 0.334
ben bendless 0.331
Rab7 Rab-protein 7 0.330
SNF1A SNF1A/AMP-activated protein kinase 0.304
CG11376 CG11376 gene product from transcript CG11376-RA 0.295
E(z) Enhancer of zeste 0.293
Mer Merlin 0.284
Mad Mothers against dpp 0.282
NaCP60E Na channel protein 60E 0.280
baz bazooka 0.277
rhea CG6831 gene product from transcript CG6831-RA 0.276
cenG1A centaurin gamma 1A 0.270
sqh spaghetti squash 0.265
pbl pebble 0.254
mop myopic 0.254
Cdc42 CG12530 gene product from transcript CG12530-RA 0.252
Jra Jun-related antigen 0.251
Rab11 Rab-protein 11 0.246
Amph Amphiphysin 0.239
WASp CG1520 gene product from transcript CG1520-RA 0.237
Galpha49B G protein alpha49B 0.228
Snap25 Synapse protein 25 0.228
neuroligin CG13772 gene product from transcript CG13772-RA 0.227
mib2 mind bomb 2 0.219
shi shibire 0.216
unc-104 CG8566 gene product from transcript CG8566-RB 0.215
Uba1 Ubiquitin activating enzyme 1 0.215
CG1021 CG1021 gene product from transcript CG1021-RE 0.213
Tl Toll 0.211
Rpd3 CG7471 gene product from transcript CG7471-RA 0.208
TSG101 tumor suppressor protein 101 0.205
neb nebbish 0.203
Pk61C Protein kinase 61C 0.203
tsr twinstar 0.189
rok Rho-kinase 0.188
puc puckered 0.186
dys dysfusion 0.184
EndoGI Endonuclease G inhibitor 0.183
cno canoe 0.183
zip zipper 0.182
CG3573 CG3573 gene product from transcript CG3573-RA 0.180
Rbsn-5 Rabenosyn-5 0.179
Fpps Farnesyl pyrophosphate synthase 0.177
Mtl Mig-2-like 0.174
ttk tramtrack 0.174
mbc myoblast city 0.173
sty sprouty 0.169
gfA giant fibre A 0.168
Pp2B-14D Protein phosphatase 2B at 14D 0.166
dos daughter of sevenless 0.164
futsch CG34387 gene product from transcript CG34387-RC 0.163
Arf79F ADP ribosylation factor 79F 0.162
CalpB Calpain-B 0.156
Dlic Dynein light intermediate chain 0.155
CycA Cyclin A 0.153
Smg1 CG32743 gene product from transcript CG32743-RA 0.152
Rme-8 Receptor mediated endocytosis 8 0.151
Ephrin CG1862 gene product from transcript CG1862-RA 0.149
MED24 Mediator complex subunit 24 0.147
wupA wings up A 0.145
stg string 0.145
porin CG6647 gene product from transcript CG6647-RA 0.145
Cip4 CG15015 gene product from transcript CG15015-RA 0.141
CG10722 CG10722 gene product from transcript CG10722-RA 0.141
Hsc70-4 Heat shock protein cognate 4 0.141
Eip63E Ecdysone-induced protein 63E 0.140
LanA Laminin A 0.139
Caps Calcium activated protein for secretion 0.138
cuff cutoff 0.138
Eph Eph receptor tyrosine kinase 0.137
CG3680 CG3680 gene product from transcript CG3680-RA 0.135
Abi Abelson interacting protein 0.134
dm diminutive 0.133
Tsc1 CG6147 gene product from transcript CG6147-RA 0.133
Pak PAK-kinase 0.132
Klc Kinesin light chain 0.132
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Homo sapiens
Name Description Probability Func Analog Organism
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
ITSN1 intersectin 1 (SH3 domain protein) 0.996
GRB2 growth factor receptor-bound protein 2 0.996
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.995
SH3KBP1 SH3-domain kinase binding protein 1 0.994
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.994
PTK2 PTK2 protein tyrosine kinase 2 0.994
SQSTM1 sequestosome 1 0.991
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.985
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.984
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.981
DNM2 dynamin 2 0.979
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.978
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.976
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.972
TRIM63 tripartite motif containing 63 0.970
GRB7 growth factor receptor-bound protein 7 0.969
ARRB1 arrestin, beta 1 0.967
FLNA filamin A, alpha 0.964
FGFR2 fibroblast growth factor receptor 2 0.960
DNM1 dynamin 1 0.960
RPA1 replication protein A1, 70kDa 0.959
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.954
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.953
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.951
SNX9 sorting nexin 9 0.948
OCRL oculocerebrorenal syndrome of Lowe 0.947
LRRK2 leucine-rich repeat kinase 2 0.943
S100A6 S100 calcium binding protein A6 0.930
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.927
NCK2 NCK adaptor protein 2 0.919
DOCK1 dedicator of cytokinesis 1 0.918
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1 0.908
TNNC1 troponin C type 1 (slow) 0.903
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.903
S100A8 S100 calcium binding protein A8 0.897
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.890
RIN3 Ras and Rab interactor 3 0.887
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.886
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.883
HIPK2 homeodomain interacting protein kinase 2 0.882
BLM Bloom syndrome, RecQ helicase-like 0.882
SFN stratifin 0.879
JUN jun proto-oncogene 0.868
APC adenomatous polyposis coli 0.865
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.864
DDX21 DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 0.861
NCF2 neutrophil cytosolic factor 2 0.861
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.857
WIPF1 WAS/WASL interacting protein family, member 1 0.855
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.852
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.850
THOC4 THO complex 4 0.836
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.836
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.835
ABI1 abl-interactor 1 0.832
GSK3B glycogen synthase kinase 3 beta 0.831
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.830
ARRB2 arrestin, beta 2 0.822
FOS FBJ murine osteosarcoma viral oncogene homolog 0.811
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.810
YY1 YY1 transcription factor 0.807
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.805
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.804
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.804
CDK7 cyclin-dependent kinase 7 0.804
CCNH cyclin H 0.793
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) 0.793
MNAT1 menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) 0.790
TRAF3 TNF receptor-associated factor 3 0.788
ARHGAP1 Rho GTPase activating protein 1 0.787
ZYX zyxin 0.786
GOLGA2 golgin A2 0.782
SMAD2 SMAD family member 2 0.777
RAB5A RAB5A, member RAS oncogene family 0.777
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.772
S100B S100 calcium binding protein B 0.768
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.768
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) 0.766
PLCG1 phospholipase C, gamma 1 0.759
CDC5L CDC5 cell division cycle 5-like (S. pombe) 0.758
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.756
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A 0.756
ZMYND11 zinc finger, MYND-type containing 11 0.753
S100A11 S100 calcium binding protein A11 0.753
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.750
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.748
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.745
ILK integrin-linked kinase 0.741
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.739
SH3RF1 SH3 domain containing ring finger 1 0.721
CCR5 chemokine (C-C motif) receptor 5 0.717
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.703
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.698
NCKAP1 NCK-associated protein 1 0.693
CFL1 cofilin 1 (non-muscle) 0.692
BRCA2 breast cancer 2, early onset 0.689
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.688
SYNJ1 synaptojanin 1 0.680
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.679
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Epha4 Eph receptor A4 0.964
Braf Braf transforming gene 0.952
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.929
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.926
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.892
Lrrk2 leucine-rich repeat kinase 2 0.891
Ephb2 Eph receptor B2 0.889
Kl klotho 0.886
Ptk2 PTK2 protein tyrosine kinase 2 0.873
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.865
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.864
Nf1 neurofibromatosis 1 0.855
Rock1 Rho-associated coiled-coil containing protein kinase 1 0.852
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.833
Arrb2 arrestin, beta 2 0.826
Ptk2b PTK2 protein tyrosine kinase 2 beta 0.809
Akt1 thymoma viral proto-oncogene 1 0.767
Rac1 RAS-related C3 botulinum substrate 1 0.759
Stxbp3a syntaxin binding protein 3A 0.758
Arpc4 actin related protein 2/3 complex, subunit 4 0.758
Bax BCL2-associated X protein 0.757
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.742
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.736
Cltc clathrin, heavy polypeptide (Hc) 0.709
Igtp interferon gamma induced GTPase 0.680
Myo1c myosin IC 0.637
Plxna1 plexin A1 0.636
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.624
Plcg1 phospholipase C, gamma 1 0.620
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 0.616
Mtor mechanistic target of rapamycin (serine/threonine kinase) 0.603
Efnb2 ephrin B2 0.599
Sox10 SRY-box containing gene 10 0.597
Eea1 early endosome antigen 1 0.592
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.591
Ulk2 Unc-51 like kinase 2 (C. elegans) 0.580
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.572
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.570
Ywhag tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.566
Pxn paxillin 0.563
Bcl2 B-cell leukemia/lymphoma 2 0.551
Pik3cd phosphatidylinositol 3-kinase catalytic delta polypeptide 0.509
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.504
Actr3 ARP3 actin-related protein 3 homolog (yeast) 0.502
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.499
Stag2 stromal antigen 2 0.493
Dlg4 discs, large homolog 4 (Drosophila) 0.485
Tgtp2 T-cell specific GTPase 2 0.482
Gdnf glial cell line derived neurotrophic factor 0.482
Rasgrp2 RAS, guanyl releasing protein 2 0.482
Src Rous sarcoma oncogene 0.480
Myo6 myosin VI 0.479
Rpgrip1l Rpgrip1-like 0.476
Tgfbr1 transforming growth factor, beta receptor I 0.472
Cnn2 calponin 2 0.466
Itga3 integrin alpha 3 0.458
Nckap1 NCK-associated protein 1 0.457
Ntf3 neurotrophin 3 0.453
Mtap2 microtubule-associated protein 2 0.450
Gnb2 guanine nucleotide binding protein (G protein), beta 2 0.446
Nsf N-ethylmaleimide sensitive fusion protein 0.443
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.439
Myo18a myosin XVIIIA 0.432
Ly6h lymphocyte antigen 6 complex, locus H 0.427
Kif5b kinesin family member 5B 0.421
Vasp vasodilator-stimulated phosphoprotein 0.419
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.419
Shc3 src homology 2 domain-containing transforming protein C3 0.416
Dbnl drebrin-like 0.414
Rab10 RAB10, member RAS oncogene family 0.414
Vapa vesicle-associated membrane protein, associated protein A 0.411
Rab5a RAB5A, member RAS oncogene family 0.410
Cttn cortactin 0.409
Pde1b phosphodiesterase 1B, Ca2+-calmodulin dependent 0.409
Ctnnd1 catenin (cadherin associated protein), delta 1 0.406
Plxnb1 plexin B1 0.406
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 0.398
Cfl1 cofilin 1, non-muscle 0.396
Pbrm1 polybromo 1 0.393
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.392
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform 0.392
Mmp15 matrix metallopeptidase 15 0.391
Clstn1 calsyntenin 1 0.391
Capza2 capping protein (actin filament) muscle Z-line, alpha 2 0.388
L1cam L1 cell adhesion molecule 0.381
Epha1 Eph receptor A1 0.378
Mapkap1 mitogen-activated protein kinase associated protein 1 0.374
Tnnt3 troponin T3, skeletal, fast 0.372
T brachyury 0.369
Wwp1 WW domain containing E3 ubiquitin protein ligase 1 0.368
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.367
Fgfr4 fibroblast growth factor receptor 4 0.365
Bmpr2 bone morphogenic protein receptor, type II (serine/threonine kinase) 0.365
Nphs2 nephrosis 2 homolog, podocin (human) 0.364
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 0.362
Sh3bp1 SH3-domain binding protein 1 0.361
Plxna3 plexin A3 0.361
Crim1 cysteine rich transmembrane BMP regulator 1 (chordin like) 0.361
Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.361
Drd2 dopamine receptor D2 0.360
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
STI1 Sti1p 0.725
ROM2 Rom2p 0.702
YPT52 Ypt52p 0.630
TFB4 Tfb4p 0.620
BEM3 Bem3p 0.614
SSL1 Ssl1p 0.563
RHO1 Rho1p 0.552
GDI1 Gdi1p 0.518
YPT1 Ypt1p 0.463
YIP3 Yip3p 0.426
KIN28 Kin28p 0.412
MKK1 Mkk1p 0.392
STE4 Ste4p 0.372
POL3 Pol3p 0.356
TOM1 Tom1p 0.344
POL30 Pol30p 0.335
ISW1 Isw1p 0.314
SUI3 Sui3p 0.301
SEC4 Sec4p 0.259
VPS15 Vps15p 0.256
FKH1 Fkh1p 0.256
SSA4 Ssa4p 0.255
TFB3 Tfb3p 0.250
STE2 Ste2p 0.243
SAC6 Sac6p 0.241
GCD6 Gcd6p 0.236
PEX1 Pex1p 0.233
SEC2 Sec2p 0.229
RPT3 Rpt3p 0.228
PRP8 Prp8p 0.211
RAD23 Rad23p 0.205
STT4 Stt4p 0.202
UNG1 Ung1p 0.194
RTT106 Rtt106p 0.189
STE5 Ste5p 0.189
KEL1 Kel1p 0.188
YCS4 Ycs4p 0.188
YDJ1 Ydj1p 0.185
SEC24 Sec24p 0.181
RFC1 Rfc1p 0.179
TSR1 Tsr1p 0.178
POL32 Pol32p 0.177
BRO1 Bro1p 0.176
VAC8 Vac8p 0.174
SEC13 Sec13p 0.172
RAD3 Rad3p 0.170
YPT10 Ypt10p 0.170
CKA1 Cka1p 0.163
SGT2 Sgt2p 0.162
ACK1 Ack1p 0.161
ESP1 Esp1p 0.161
HYP2 Hyp2p 0.160
STE20 Ste20p 0.159
SEC16 Sec16p 0.156
CCL1 Ccl1p 0.156
UFD2 Ufd2p 0.155
VPS4 Vps4p 0.150
RAS1 Ras1p 0.149
TFB5 Tfb5p 0.145
NOG2 Nog2p 0.142
VPS21 Vps21p 0.141
SPA2 Spa2p 0.136
MRE11 Mre11p 0.133
MOT1 Mot1p 0.132
CDC50 Cdc50p 0.131
SSL2 Ssl2p 0.131
BEM4 Bem4p 0.130
SEC53 Sec53p 0.129
ORC2 Orc2p 0.128
PRR1 Prr1p 0.127
KEX1 Kex1p 0.125
YLR257W hypothetical protein 0.125
HSP104 Hsp104p 0.124
SAR1 Sar1p 0.124
KOG1 Kog1p 0.123
BFR1 Bfr1p 0.120
VPS13 Vps13p 0.120
YPT6 Ypt6p 0.118
RAD52 Rad52p 0.114
MEH1 Meh1p 0.112
MCA1 Mca1p 0.112
ELG1 Elg1p 0.111
NYV1 Nyv1p 0.111
TRS65 Trs65p 0.111
GIC2 Gic2p 0.111
SEC3 Sec3p 0.111
MDS3 Mds3p 0.110
RSC9 Rsc9p 0.110
INO80 Ino80p 0.109
MYO4 Myo4p 0.106
CDS1 Cds1p 0.105
PKC1 Pkc1p 0.104
CAK1 Cak1p 0.103
KRS1 Krs1p 0.103
RAD4 Rad4p 0.102
HSC82 Hsc82p 0.102
KEM1 Kem1p 0.102
ERB1 Erb1p 0.101
IRA1 Ira1p 0.101
YPT7 Ypt7p 0.101