The network for 'positive regulation of nervous system development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of nervous system development

Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.

Rattus norvegicus
Name Description Probability Func Analog Organism
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.593
Ccl2 chemokine (C-C motif) ligand 2 0.504
Fgfr2 fibroblast growth factor receptor 2 0.482
Il1b interleukin 1 beta 0.460
Itpkb inositol 1,4,5-trisphosphate 3-kinase B 0.403
Rap1b RAP1B, member of RAS oncogene family 0.383
Dlgap2 discs, large (Drosophila) homolog-associated protein 2 0.381
Cxcl2 chemokine (C-X-C motif) ligand 2 0.326
Map2 microtubule-associated protein 2 0.319
Ncam1 neural cell adhesion molecule 1 0.319
Nfia nuclear factor I/A 0.318
Anxa2 annexin A2 0.284
Jak1 Janus kinase 1 0.279
Cd4 Cd4 molecule 0.274
Nfasc neurofascin 0.272
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) 0.269
Anxa5 annexin A5 0.260
Ccl20 chemokine (C-C motif) ligand 20 0.258
Slit3 slit homolog 3 (Drosophila) 0.257
Cxcl10 chemokine (C-X-C motif) ligand 10 0.255
Bcl2 B-cell CLL/lymphoma 2 0.254
C5ar1 complement component 5a receptor 1 0.248
Hck hemopoietic cell kinase 0.243
Rims1 regulating synaptic membrane exocytosis 1 0.241
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.241
Bmp6 bone morphogenetic protein 6 0.240
Dchs1 dachsous 1 (Drosophila) 0.238
Nfib nuclear factor I/B 0.234
Grm7 glutamate receptor, metabotropic 7 0.229
Myo1c myosin IC 0.223
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.222
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.216
Ccr3 chemokine (C-C motif) receptor 3 0.211
Abcc1 ATP-binding cassette, subfamily C (CFTR/MRP), member 1 0.207
Gria2 glutamate receptor, ionotropic, AMPA 2 0.203
Pde3a phosphodiesterase 3A, cGMP inhibited 0.199
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.198
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.196
Rdh2 retinol dehydrogenase 2 0.195
Cga glycoprotein hormones, alpha polypeptide 0.191
Il1a interleukin 1 alpha 0.188
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.188
Nefm neurofilament, medium polypeptide 0.187
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.184
Tagln3 transgelin 3 0.184
Cugbp2 CUG triplet repeat, RNA binding protein 2 0.183
Prl8a9 prolactin family 8, subfamily a, member 9 0.181
Slco2a1 solute carrier organic anion transporter family, member 2a1 0.180
Itpr1 inositol 1,4,5-triphosphate receptor, type 1 0.180
Grin2a glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.177
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 0.176
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.176
Cd8a CD8a molecule 0.174
Mif macrophage migration inhibitory factor 0.172
Klc2 kinesin light chain 2 0.172
Hspb1 heat shock protein 1 0.172
Nlgn1 neuroligin 1 0.171
Foxj1 forkhead box J1 0.170
Ccdc102a coiled-coil domain containing 102A 0.170
Rab20 RAB20, member RAS oncogene family 0.169
Epha5 EphA5 0.168
Shc2 SHC (Src homology 2 domain containing) transforming protein 2 0.168
Gcgr glucagon receptor 0.168
Adam17 ADAM metallopeptidase domain 17 0.167
Nefl neurofilament, light polypeptide 0.165
Lphn2 latrophilin 2 0.163
Tgfbr2 transforming growth factor, beta receptor II 0.163
Pou3f2 POU class 3 homeobox 2 0.161
Grpr gastrin releasing peptide receptor 0.161
Gprasp1 G protein-coupled receptor associated sorting protein 1 0.159
Tcf4 transcription factor 4 0.159
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.158
Nrxn1 neurexin 1 0.157
Gja1 gap junction protein, alpha 1 0.150
Pecam1 platelet/endothelial cell adhesion molecule 1 0.149
Ptprs protein tyrosine phosphatase, receptor type, S 0.149
Epo erythropoietin 0.149
Acvr1 activin A receptor, type I 0.149
Ptafr platelet-activating factor receptor 0.147
Gper G protein-coupled estrogen receptor 1 0.145
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 0.145
Tas2r107 taste receptor, type 2, member 107 0.143
Fyn FYN oncogene related to SRC, FGR, YES 0.143
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.142
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.141
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 0.141
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.141
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.139
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.138
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.137
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.137
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.137
Nefh neurofilament, heavy polypeptide 0.136
Slc6a7 solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 0.136
Hes5 hairy and enhancer of split 5 (Drosophila) 0.136
Arpc5 actin related protein 2/3 complex, subunit 5 0.136
Ciita class II, major histocompatibility complex, transactivator 0.134
Scnn1g sodium channel, nonvoltage-gated 1, gamma 0.133
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.131
Neurod2 neurogenic differentiation 2 0.131
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
par-5 Protein PAR-5 0.308
elt-6 Protein ELT-6 0.287
pha-4 Protein PHA-4 0.139
nhr-67 Protein NHR-67 0.129
egl-46 Protein EGL-46 0.088
lin-17 Protein LIN-17 0.085
lin-29 Protein LIN-29 0.083
egl-15 Protein EGL-15 0.073
sem-5 Protein SEM-5 0.068
hlh-2 Protein HLH-2 0.066
ten-1 Protein TEN-1 0.066
egl-18 Protein EGL-18 0.060
egl-30 Protein EGL-30 0.057
goa-1 Protein GOA-1 0.055
gsp-1 Protein GSP-1 0.053
cdc-42 Protein CDC-42 0.050
ztf-2 Protein ZTF-2 0.036
unc-9 Protein UNC-9 0.036
lag-1 Protein LAG-1 0.035
let-60 Protein LET-60 0.030
R10E12.2 Protein R10E12.2 0.026
egl-27 Protein EGL-27 0.024
K08E3.5 Protein K08E3.5 0.023
inx-3 Protein INX-3 0.022
sas-5 Protein SAS-5 0.021
egl-13 Protein EGL-13 0.020
ptp-1 Protein PTP-1 0.020
cdl-1 Protein CDL-1 0.019
unc-32 Protein UNC-32 0.019
ncam-1 Protein NCAM-1 0.018
unc-73 Protein UNC-73 0.018
bar-1 Protein BAR-1 0.018
igcm-3 Protein IGCM-3 0.018
hlh-30 Protein HLH-30 0.017
cdh-3 Protein CDH-3 0.017
rhgf-2 Protein RHGF-2 0.017
lat-1 Protein LAT-1 0.016
pry-1 Protein PRY-1 0.016
soc-2 Protein SOC-2 0.016
madf-5 Protein MADF-5 0.016
tmc-2 Protein TMC-2 0.015
C10G11.7 Protein C10G11.7 0.015
unc-62 Protein UNC-62 0.015
syd-2 Protein SYD-2 0.014
sel-8 Protein SEL-8 0.014
C11E4.6 Protein C11E4.6 0.014
pxf-1 Protein PXF-1 0.014
hlh-1 Protein HLH-1 0.013
vab-3 Protein VAB-3 0.013
etr-1 Protein ETR-1 0.012
nfyb-1 Protein NFYB-1 0.012
hnd-1 Protein HND-1 0.012
egl-36 Protein EGL-36 0.012
dbl-1 Protein DBL-1 0.012
cit-1.1 Protein CIT-1.1 0.012
pdfr-1 Protein PDFR-1 0.011
cnd-1 Protein CND-1 0.011
dpy-6 Protein DPY-6 0.011
unc-70 Protein UNC-70 0.010
rpy-1 Protein RPY-1 0.010
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Danio rerio
Name Description Probability Func Analog Organism
ascl1a achaete-scute complex-like 1a (Drosophila) 0.957
cdh2 cadherin 2, neuronal 0.879
pax6a paired box gene 6a 0.868
bmp2b bone morphogenetic protein 2b 0.815
fgf8a fibroblast growth factor 8 a 0.733
alcama activated leukocyte cell adhesion molecule a 0.664
isl1 islet1 0.650
gli1 GLI-Kruppel family member 1 0.620
tal1 T-cell acute lymphocytic leukemia 1 0.615
chd chordin 0.570
dlx5a distal-less homeobox gene 5a 0.541
neurod neurogenic differentiation 0.512
kdrl kinase insert domain receptor like 0.507
ptf1a pancreas specific transcription factor, 1a 0.499
phox2a paired-like homeobox 2a 0.482
olig2 oligodendrocyte lineage transcription factor 2 0.479
boc brother of CDO 0.471
foxa1 forkhead box A1 0.460
pax2a paired box gene 2a 0.417
met met proto-oncogene (hepatocyte growth factor receptor) 0.404
pitx3 paired-like homeodomain transcription factor 3 0.391
gata2a GATA-binding protein 2a 0.390
dlc deltaC 0.383
foxd3 forkhead box D3 0.372
lhx1a LIM homeobox 1a 0.365
neo1 neogenin 1 0.365
pax8 paired box gene 8 0.352
shha sonic hedgehog a 0.345
prdm1a PR domain containing 1a, with ZNF domain 0.336
gata3 GATA-binding protein 3 0.328
evx1 even-skipped homeobox 1 0.293
rx3 retinal homeobox gene 3 0.286
gata6 GATA-binding protein 6 0.278
dld deltaD 0.276
gsna gelsolin a 0.267
pitx2 paired-like homeodomain transcription factor 2 0.252
robo2 roundabout homolog 2 0.250
tac1 tachykinin 1 0.241
wnt11r wingless-type MMTV integration site family, member 11, related 0.239
spry4 sprouty (Drosophila) homolog 4 0.239
meis2.2 myeloid ecotropic viral integration site 2.2 0.234
gdf6a growth differentiation factor 6a 0.231
sox2 SRY-box containing gene 2 0.231
otx1b orthodenticle homolog 1b 0.209
dlb deltaB 0.206
gli2a GLI-Kruppel family member GLI2a 0.195
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.191
dla deltaA 0.185
phox2b paired-like homeobox 2b 0.181
bmp4 bone morphogenetic protein 4 0.180
smad1 MAD homolog 1 (Drosophila) 0.180
pea3 ETS-domain transcription factor pea3 0.177
nr2e1 nuclear receptor subfamily 2, group E, member 1 0.177
lmx1b.1 LIM homeobox transcription factor 1, beta 1 0.171
cdh1 cadherin 1, epithelial 0.169
fgfr4 fibroblast growth factor receptor 4 0.169
fgfr2 fibroblast growth factor receptor 2 0.166
shhb sonic hedgehog b 0.164
nkx2.2a NK2 transcription factor related 2a 0.163
otpb orthopedia homolog b 0.159
foxn4 forkhead box N4 0.159
dcc deleted in colorectal carcinoma 0.159
arx aristaless related homeobox 0.158
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.149
snai1a snail homolog 1a (Drosophila) 0.147
smad9 MAD homolog 9 (Drosophila) 0.146
six3b sine oculis homeobox homolog 3b 0.142
nipblb novel protein similar to vertebrate Nipped-B homolog and nipped-b homolog b (Drosophila) 0.140
otx2 orthodenticle homolog 2 0.137
hhip hedgehog interacting protein 0.135
tp63 tumor protein p63 0.130
nrp2b neuropilin 2b 0.124
fezf2 FEZ family zinc finger 2 0.121
tuba1l tubulin, alpha 1, like 0.120
slit3 slit (Drosophila) homolog 3 0.120
traf4a tnf receptor-associated factor 4a 0.118
cyp26a1 cytochrome P450, subfamily XXVIA, polypeptide 1 0.116
lamb1a laminin, beta 1a 0.115
gbx2 gastrulation brain homeo box 2 0.114
jag2 jagged 2 0.111
atoh7 atonal homolog 7 0.105
alp alkaline phosphatase 0.104
bmp2a bone morphogenetic protein 2a 0.102
lmo4a LIM domain only 4a 0.102
ntla no tail a 0.100
otx5 orthodenticle homolog 5 0.098
gnrh2 gonadotropin-releasing hormone 2 0.098
rasgef1ba RasGEF domain family, member 1Ba 0.095
flh floating head 0.094
tmem2 transmembrane protein 2 0.092
vsx1 visual system homeobox 1 homolog, chx10-like 0.090
wnt4a wingless-type MMTV integration site family, member 4a 0.088
nrg2a neuregulin 2a 0.088
fsta follistatin a 0.087
foxa2 forkhead box A2 0.086
six4b sine oculis homeobox homolog 4b 0.086
copeb core promoter element binding protein 0.086
angptl2 angiopoietin-like 2 0.085
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.085
irx4a iroquois homeobox protein 4a 0.084
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Ras85D Ras oncogene at 85D 0.999
phl pole hole 0.987
Sema-1a CG18405 gene product from transcript CG18405-RD 0.977
N Notch 0.969
spi spitz 0.951
Dap160 Dynamin associated protein 160 0.931
shot short stop 0.927
ato atonal 0.913
HLHm7 E(spl) region transcript m7 0.904
trio CG18214 gene product from transcript CG18214-RA 0.902
dsh dishevelled 0.901
robo roundabout 0.895
Egfr Epidermal growth factor receptor 0.886
NetB Netrin-B 0.876
Liprin-alpha CG11199 gene product from transcript CG11199-RB 0.862
Mad Mothers against dpp 0.857
Fmr1 CG6203 gene product from transcript CG6203-RC 0.857
wg wingless 0.851
robo3 CG5423 gene product from transcript CG5423-RA 0.808
E(spl) Enhancer of split 0.793
Su(H) Suppressor of Hairless 0.792
TBPH CG10327 gene product from transcript CG10327-RC 0.788
rho rhomboid 0.780
sgg shaggy 0.740
ctp cut up 0.713
Ptp69D Protein tyrosine phosphatase 69D 0.711
unc-104 CG8566 gene product from transcript CG8566-RB 0.680
HLHmgamma E(spl) region transcript mgamma 0.670
neur neuralized 0.624
Mical Molecule interacting with CasL 0.622
jeb jelly belly 0.621
mam mastermind 0.616
dally division abnormally delayed 0.613
rictor rapamycin-insensitive companion of Tor 0.610
htl heartless 0.601
tutl turtle 0.590
Eph Eph receptor tyrosine kinase 0.588
ab abrupt 0.581
eya eyes absent 0.573
numb CG3779 gene product from transcript CG3779-RB 0.562
Ubx Ultrabithorax 0.560
Caps Calcium activated protein for secretion 0.559
dock dreadlocks 0.558
vvl ventral veins lacking 0.555
arm armadillo 0.542
abd-A abdominal A 0.541
gro groucho 0.533
milt milton 0.503
Trim9 CG31721 gene product from transcript CG31721-RB 0.497
HLHmbeta E(spl) region transcript mbeta 0.488
nwk nervous wreck 0.486
Nrg Neuroglian 0.478
dpn deadpan 0.478
pros prospero 0.477
rl rolled 0.472
Pak PAK-kinase 0.454
tkv thickveins 0.448
katanin-60 katanin 60 0.447
Dl Delta 0.444
ptc patched 0.436
fz2 frizzled 2 0.434
ey eyeless 0.432
CG12424 CG12424 gene product from transcript CG12424-RC 0.427
Abl Abl tyrosine kinase 0.416
gcm glial cells missing 0.412
Sos Son of sevenless 0.411
Stat92E Signal-transducer and activator of transcription protein at 92E 0.400
ci cubitus interruptus 0.400
Cip4 CG15015 gene product from transcript CG15015-RA 0.397
neuroligin CG13772 gene product from transcript CG13772-RA 0.396
HLHm5 E(spl) region transcript m5 0.393
ena enabled 0.389
slmb supernumerary limbs 0.388
pnt pointed 0.377
nej nejire 0.374
CG11347 CG11347 gene product from transcript CG11347-RE 0.371
sc scute 0.350
CrebB-17A Cyclic-AMP response element binding protein B at 17A 0.348
hh hedgehog 0.345
CaMKII Calcium/calmodulin-dependent protein kinase II 0.343
chic chickadee 0.338
comm commissureless 0.336
lea leak 0.328
caz cabeza 0.326
ac achaete 0.325
Ank2 Ankyrin 2 0.308
Sep2 Septin-2 0.308
sfl sulfateless 0.302
ems empty spiracles 0.300
rap retina aberrant in pattern 0.297
emc extra macrochaetae 0.276
spas spastin 0.265
tsr twinstar 0.264
Pk61C Protein kinase 61C 0.252
trc tricornered 0.248
amos absent MD neurons and olfactory sensilla 0.248
hiw highwire 0.241
ttv tout-velu 0.234
WASp CG1520 gene product from transcript CG1520-RA 0.233
shg shotgun 0.232
Loading network...
Homo sapiens
Name Description Probability Func Analog Organism
EGFR epidermal growth factor receptor 0.996
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.958
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.937
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.895
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.861
FYN FYN oncogene related to SRC, FGR, YES 0.758
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.755
LCK lymphocyte-specific protein tyrosine kinase 0.696
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.672
PLCG1 phospholipase C, gamma 1 0.661
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.658
HDAC1 histone deacetylase 1 0.569
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.460
BCAR1 breast cancer anti-estrogen resistance 1 0.426
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.414
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.401
GRB2 growth factor receptor-bound protein 2 0.400
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.400
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.400
MET met proto-oncogene (hepatocyte growth factor receptor) 0.399
MAPT microtubule-associated protein tau 0.394
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.366
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.365
HDAC4 histone deacetylase 4 0.361
ATXN1 ataxin 1 0.359
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.338
DNM1 dynamin 1 0.328
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.326
FASLG Fas ligand (TNF superfamily, member 6) 0.314
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.301
SMAD7 SMAD family member 7 0.297
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.289
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.249
TRIO triple functional domain (PTPRF interacting) 0.245
RUNX1 runt-related transcription factor 1 0.242
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4 0.238
MAP2K1 mitogen-activated protein kinase kinase 1 0.229
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.227
PTPRC protein tyrosine phosphatase, receptor type, C 0.227
AMPH amphiphysin 0.216
NCK1 NCK adaptor protein 1 0.216
BMPR1A bone morphogenetic protein receptor, type IA 0.212
VEGFA vascular endothelial growth factor A 0.210
BMP2 bone morphogenetic protein 2 0.208
GSK3B glycogen synthase kinase 3 beta 0.204
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.204
CCR5 chemokine (C-C motif) receptor 5 0.201
GAB1 GRB2-associated binding protein 1 0.200
PLAU plasminogen activator, urokinase 0.199
SPRR2A small proline-rich protein 2A 0.199
POU3F2 POU class 3 homeobox 2 0.190
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta) 0.185
APC adenomatous polyposis coli 0.181
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.179
TRIM33 tripartite motif containing 33 0.175
WIPF1 WAS/WASL interacting protein family, member 1 0.171
SNX9 sorting nexin 9 0.169
TNK2 tyrosine kinase, non-receptor, 2 0.168
HIPK2 homeodomain interacting protein kinase 2 0.163
FLNA filamin A, alpha 0.155
HDAC2 histone deacetylase 2 0.144
QKI quaking homolog, KH domain RNA binding (mouse) 0.141
IER3 immediate early response 3 0.139
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.138
PDX1 pancreatic and duodenal homeobox 1 0.135
TAL1 T-cell acute lymphocytic leukemia 1 0.133
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.131
PTK2 PTK2 protein tyrosine kinase 2 0.131
SKI v-ski sarcoma viral oncogene homolog (avian) 0.131
APLF aprataxin and PNKP like factor 0.130
JAG1 jagged 1 0.128
AR androgen receptor 0.127
FGF1 fibroblast growth factor 1 (acidic) 0.126
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.123
NCOR1 nuclear receptor corepressor 1 0.123
GHR growth hormone receptor 0.123
ITGB4 integrin, beta 4 0.115
GH1 growth hormone 1 0.114
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) 0.111
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.109
RHOC ras homolog gene family, member C 0.109
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.106
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.105
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 0.104
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen) 0.104
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.104
TBX5 T-box 5 0.103
PDLIM7 PDZ and LIM domain 7 (enigma) 0.100
RERE arginine-glutamic acid dipeptide (RE) repeats 0.099
GOLGA2 golgin A2 0.098
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.095
LAT linker for activation of T cells 0.095
PRKCE protein kinase C, epsilon 0.094
GRB10 growth factor receptor-bound protein 10 0.094
PRMT1 protein arginine methyltransferase 1 0.092
HCK hemopoietic cell kinase 0.092
ZNF746 zinc finger protein 746 0.092
JAK2 Janus kinase 2 0.091
NCOR2 nuclear receptor corepressor 2 0.091
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.089
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Mus musculus
Name Description Probability Func Analog Organism
Foxc1 forkhead box C1 1.000
Pten phosphatase and tensin homolog 0.999
Shh sonic hedgehog 0.999
Ret ret proto-oncogene 0.997
Fgf8 fibroblast growth factor 8 0.996
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.995
Gli2 GLI-Kruppel family member GLI2 0.994
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.994
Hand2 heart and neural crest derivatives expressed transcript 2 0.994
Gli3 GLI-Kruppel family member GLI3 0.994
Nkx2-5 NK2 transcription factor related, locus 5 (Drosophila) 0.991
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.989
Bcl2 B-cell leukemia/lymphoma 2 0.988
Pax3 paired box gene 3 0.988
Ctnnb1 catenin (cadherin associated protein), beta 1 0.986
Otx2 orthodenticle homolog 2 (Drosophila) 0.985
Fgfr2 fibroblast growth factor receptor 2 0.978
Gdnf glial cell line derived neurotrophic factor 0.977
Ntf3 neurotrophin 3 0.976
Dlg4 discs, large homolog 4 (Drosophila) 0.975
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.971
Smad3 MAD homolog 3 (Drosophila) 0.969
Emx1 empty spiracles homolog 1 (Drosophila) 0.968
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.964
Tgfb2 transforming growth factor, beta 2 0.963
Meox2 mesenchyme homeobox 2 0.953
Pax6 paired box gene 6 0.953
Dab1 disabled homolog 1 (Drosophila) 0.951
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.947
Ikzf1 IKAROS family zinc finger 1 0.946
Pbx1 pre B-cell leukemia transcription factor 1 0.937
Ednrb endothelin receptor type B 0.937
Foxc2 forkhead box C2 0.933
Pax2 paired box gene 2 0.931
Hoxa1 homeobox A1 0.930
Fgf10 fibroblast growth factor 10 0.929
Fgfr1 fibroblast growth factor receptor 1 0.929
Hoxd3 homeobox D3 0.926
Lepr leptin receptor 0.925
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.920
Tbx1 T-box 1 0.919
Isl1 ISL1 transcription factor, LIM/homeodomain 0.917
Dicer1 Dicer1, Dcr-1 homolog (Drosophila) 0.908
Erbb2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.906
Smad6 MAD homolog 6 (Drosophila) 0.904
Sox9 SRY-box containing gene 9 0.889
Myod1 myogenic differentiation 1 0.887
Vangl2 vang-like 2 (van gogh, Drosophila) 0.884
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.881
Snai1 snail homolog 1 (Drosophila) 0.879
Msx1 homeobox, msh-like 1 0.878
Twist2 twist homolog 2 (Drosophila) 0.875
Hand1 heart and neural crest derivatives expressed transcript 1 0.870
Bdnf brain derived neurotrophic factor 0.868
Bmp4 bone morphogenetic protein 4 0.864
Hoxd11 homeobox D11 0.863
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.854
Vegfa vascular endothelial growth factor A 0.853
Pou3f3 POU domain, class 3, transcription factor 3 0.845
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.844
Cdc42 cell division cycle 42 homolog (S. cerevisiae) 0.844
Dcc deleted in colorectal carcinoma 0.843
Zic3 zinc finger protein of the cerebellum 3 0.841
Apc adenomatosis polyposis coli 0.838
Sox10 SRY-box containing gene 10 0.837
Meis2 Meis homeobox 2 0.832
Plcg1 phospholipase C, gamma 1 0.832
Ptf1a pancreas specific transcription factor, 1a 0.830
Nhlh1 nescient helix loop helix 1 0.830
Fzd1 frizzled homolog 1 (Drosophila) 0.827
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.820
Foxa2 forkhead box A2 0.816
Prrx1 paired related homeobox 1 0.812
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.811
Cd44 CD44 antigen 0.806
Lhx1 LIM homeobox protein 1 0.805
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.802
Smo smoothened homolog (Drosophila) 0.797
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.793
Nf1 neurofibromatosis 1 0.793
Sez6l seizure related 6 homolog like 0.792
Ephb2 Eph receptor B2 0.791
Gas1 growth arrest specific 1 0.787
Chrd chordin 0.783
Adam17 a disintegrin and metallopeptidase domain 17 0.783
Ptk2 PTK2 protein tyrosine kinase 2 0.783
Kit kit oncogene 0.782
Lhx9 LIM homeobox protein 9 0.777
Neurog2 neurogenin 2 0.776
Egfr epidermal growth factor receptor 0.776
Prkce protein kinase C, epsilon 0.767
Ntn1 netrin 1 0.766
Nog noggin 0.765
Cxcl12 chemokine (C-X-C motif) ligand 12 0.758
Nos3 nitric oxide synthase 3, endothelial cell 0.758
Drd2 dopamine receptor D2 0.751
Prox1 prospero-related homeobox 1 0.750
Notch3 Notch gene homolog 3 (Drosophila) 0.749
Mab21l2 mab-21-like 2 (C. elegans) 0.749
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.745
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism