The network for 'positive regulation of cellular biosynthetic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of cellular biosynthetic process

Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.

Name Description Probability Func Analog Organism
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.717
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a 0.594
Tgfbr2 transforming growth factor, beta receptor II 0.552
Rara retinoic acid receptor, alpha 0.549
Fgfr2 fibroblast growth factor receptor 2 0.519
Ppp1r15a protein phosphatase 1, regulatory (inhibitor) subunit 15A 0.506
Dusp1 dual specificity phosphatase 1 0.459
Junb jun B proto-oncogene 0.454
Pou2f2 POU class 2 homeobox 2 0.449
Oxtr oxytocin receptor 0.434
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 0.427
Klf6 Kruppel-like factor 6 0.423
Bst1 bone marrow stromal cell antigen 1 0.422
Ccl2 chemokine (C-C motif) ligand 2 0.411
Nfib nuclear factor I/B 0.409
Mrgprf MAS-related GPR, member F 0.406
Tcfe2a transcription factor E2a 0.405
Vdr vitamin D (1,25- dihydroxyvitamin D3) receptor 0.401
S100a10 S100 calcium binding protein A10 0.388
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.388
Nkx6-1 NK6 homeobox 1 0.378
Jak1 Janus kinase 1 0.376
Fgfr1 Fibroblast growth factor receptor 1 0.374
Cxcl10 chemokine (C-X-C motif) ligand 10 0.367
Hcrtr1 hypocretin (orexin) receptor 1 0.362
Ptma prothymosin alpha 0.361
Plcg2 phospholipase C, gamma 2 0.354
Drd3 dopamine receptor D3 0.346
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.344
Ccl3 chemokine (C-C motif) ligand 3 0.344
Ncl nucleolin 0.341
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 0.337
Map3k1 mitogen activated protein kinase kinase kinase 1 0.331
Foxd3 forkhead box D3 0.321
Jun Jun oncogene 0.320
Jtb jumping translocation breakpoint 0.320
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.318
Errfi1 ERBB receptor feedback inhibitor 1 0.311
Iapp islet amyloid polypeptide 0.311
Il8ra interleukin 8 receptor, alpha 0.310
Fos FBJ osteosarcoma oncogene 0.308
Mmp12 matrix metallopeptidase 12 0.302
Ccl4 chemokine (C-C motif) ligand 4 0.301
Foxo1 forkhead box O1 0.299
Fut4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.296
Runx1 runt-related transcription factor 1 0.287
Myadm myeloid-associated differentiation marker 0.285
Insr insulin receptor 0.283
C5ar1 complement component 5a receptor 1 0.281
Itgam integrin, alpha M 0.281
Lims1 LIM and senescent cell antigen-like domains 1 0.279
Nr5a2 nuclear receptor subfamily 5, group A, member 2 0.279
Nr1d1 nuclear receptor subfamily 1, group D, member 1 0.278
Purb purine rich element binding protein B 0.275
Zfp36l1 zinc finger protein 36, C3H type-like 1 0.275
Cd86 CD86 molecule 0.274
Gucy2g guanylate cyclase 2G 0.262
Foxa3 forkhead box A3 0.260
Nos1 nitric oxide synthase 1, neuronal 0.259
Cd40lg CD40 ligand 0.258
Notch3 Notch homolog 3 (Drosophila) 0.257
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.256
Bdkrb2 bradykinin receptor B2 0.255
Olr1271 olfactory receptor 1271 0.254
Cyss cystatin S 0.252
Cdkn2b cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.252
Cd8b CD8b molecule 0.251
Tcf4 transcription factor 4 0.250
Rhob ras homolog gene family, member B 0.250
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.249
Stat6 signal transducer and activator of transcription 6 0.246
Prlhr prolactin releasing hormone receptor 0.244
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 0.243
Grk1 G protein-coupled receptor kinase 1 0.243
Ccr5 chemokine (C-C motif) receptor 5 0.243
Ccnd3 cyclin D3 0.240
RGD1564560 similar to RCK 0.239
Myc myelocytomatosis oncogene 0.238
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.238
Add2 adducin 2 (beta) 0.237
Nr4a2 nuclear receptor subfamily 4, group A, member 2 0.236
Cst8 cystatin 8 (cystatin-related epididymal specific) 0.235
Cfd complement factor D (adipsin) 0.235
Zfp36 zinc finger protein 36 0.232
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.230
Cdc34 cell division cycle 34 homolog (S. cerevisiae) 0.230
Cnga1 cyclic nucleotide gated channel alpha 1 0.229
Cxcl6 chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) 0.228
Ccdc49 coiled-coil domain containing 49 0.226
Adam17 ADAM metallopeptidase domain 17 0.224
Chrnb4 cholinergic receptor, nicotinic, beta 4 0.223
Il2ra interleukin 2 receptor, alpha 0.223
Lphn2 latrophilin 2 0.222
Ascl1 achaete-scute complex homolog 1 (Drosophila) 0.221
Vim vimentin 0.219
Tmem45b transmembrane protein 45b 0.219
Pdyn prodynorphin 0.218
Grin3a glutamate receptor, ionotropic, N-methyl-D-aspartate 3A 0.216
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.216
Atf3 activating transcription factor 3 0.216
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
elt-6 Protein ELT-6 1.000
vab-3 Protein VAB-3 0.999
egl-18 Protein EGL-18 0.998
pha-4 Protein PHA-4 0.995
hlh-2 Protein HLH-2 0.941
nhr-49 Protein NHR-49 0.907
flt-1 Protein FLT-1 0.859
unc-37 Protein UNC-37 0.795
vab-1 Protein VAB-1 0.792
cam-1 Protein CAM-1 0.789
fkh-2 Protein FKH-2 0.788
eya-1 Protein EYA-1 0.784
mat-3 Protein MAT-3 0.778
his-64 Protein HIS-64 0.773
hlh-1 Protein HLH-1 0.771
lin-36 Protein LIN-36 0.749
egl-13 Protein EGL-13 0.735
pop-1 Protein POP-1 0.727
nhr-6 Protein NHR-6 0.693
unc-42 Protein UNC-42 0.691
zip-7 Protein ZIP-7 0.677
nhr-67 Protein NHR-67 0.674
gei-4 Protein GEI-4 0.665
rps-2 Protein RPS-2 0.646
unc-40 Protein UNC-40 0.633
pry-1 Protein PRY-1 0.617
mab-5 Protein MAB-5 0.615
unc-62 Protein UNC-62 0.614
rad-26 Protein RAD-26 0.599
skp-1 Protein SKP-1 0.573
egl-46 Protein EGL-46 0.568
lin-17 Protein LIN-17 0.552
mep-1 Protein MEP-1 0.549
iff-1 Protein IFF-1 0.543
his-46 Protein HIS-46 0.535
lin-12 Protein LIN-12 0.519
B0035.1 Protein B0035.1 0.518
hbl-1 Protein HBL-1 0.513
R11A8.7 Protein R11A8.7 0.498
hnd-1 Protein HND-1 0.492
flh-2 Protein FLH-2 0.490
ten-1 Protein TEN-1 0.478
bar-1 Protein BAR-1 0.473
tax-4 Protein TAX-4 0.472
dlk-1 Protein DLK-1 0.470
lag-1 Protein LAG-1 0.468
F53F10.2 Protein F53F10.2 0.457
npp-2 Protein NPP-2 0.450
D1081.8 Protein D1081.8 0.446
mls-2 Protein MLS-2 0.436
daf-1 Protein DAF-1 0.428
his-5 Protein HIS-5 0.426
cki-1 Protein CKI-1 0.425
tag-298 Protein TAG-298 0.415
cnd-1 Protein CND-1 0.414
sas-5 Protein SAS-5 0.413
ldb-1 Protein LDB-1 0.410
tbx-9 Protein TBX-9 0.404
daf-16 Protein DAF-16 0.374
ceh-22 Protein CEH-22 0.370
ceh-27 Protein CEH-27 0.368
icd-1 Protein ICD-1 0.364
his-31 Protein HIS-31 0.363
his-1 Protein HIS-1 0.360
hlh-14 Protein HLH-14 0.358
soc-2 Protein SOC-2 0.352
ras-1 Protein RAS-1 0.347
CELE_C17E4.6 Protein C17E4.6 0.345
dpy-22 Protein DPY-22 0.341
attf-2 Protein ATTF-2 0.339
pac-1 Protein PAC-1 0.338
hrp-1 Protein HRP-1 0.334
set-1 Protein SET-1 0.330
cfim-2 Protein CFIM-2 0.324
dmd-6 Protein DMD-6 0.320
kin-10 Protein KIN-10 0.315
pdfr-1 Protein PDFR-1 0.308
zyg-1 Protein ZYG-1 0.306
mdt-8 Protein MDT-8 0.303
ztf-2 Protein ZTF-2 0.301
tct-1 Protein TCT-1 0.299
ced-5 Protein CED-5 0.294
tbx-8 Protein TBX-8 0.290
wrm-1 Protein WRM-1 0.282
K10D6.4 Protein K10D6.4 0.268
lin-35 Protein LIN-35 0.268
ref-1 Protein REF-1 0.266
hum-5 Protein HUM-5 0.262
T28D9.4 Protein T28D9.4 0.258
daf-11 Protein DAF-11 0.256
mcm-7 Protein MCM-7 0.255
mab-31 Protein MAB-31 0.254
zyg-9 Protein ZYG-9 0.253
lin-1 Protein LIN-1 0.251
ced-9 Protein CED-9 0.250
sad-1 Protein SAD-1 0.244
unc-73 Protein UNC-73 0.244
his-62 Protein HIS-62 0.243
ceh-16 Protein CEH-16 0.240
T09B4.5 Protein T09B4.5 0.235
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Danio rerio
Name Description Probability Func Analog Organism
nkx2.2a NK2 transcription factor related 2a 0.982
dlx5a distal-less homeobox gene 5a 0.973
tp53 tumor protein p53 0.972
ndr2 nodal-related 2 0.938
kdrl kinase insert domain receptor like 0.927
pitx3 paired-like homeodomain transcription factor 3 0.923
gata3 GATA-binding protein 3 0.895
ascl1a achaete-scute complex-like 1a (Drosophila) 0.869
flh floating head 0.863
eya1 eyes absent homolog 1 0.847
notch1a notch homolog 1a 0.832
shha sonic hedgehog a 0.801
crabp2a cellular retinoic acid binding protein 2, a 0.790
runx2b runt-related transcription factor 2b 0.765
foxi1 forkhead box I1 0.762
myod1 myogenic differentiation 1 0.752
dlx2a distal-less homeobox gene 2a 0.741
gli1 GLI-Kruppel family member 1 0.728
hoxb1b homeo box B1b 0.708
six1b sine oculis homeobox homolog 1b 0.696
tbx1 T-box 1 0.695
hand2 heart and neural crest derivatives expressed transcript 2 0.680
otpa orthopedia homolog a 0.675
hnf1ba HNF1 homeobox Ba 0.670
cdx4 caudal type homeo box transcription factor 4 0.653
rxrab retinoid x receptor, alpha b 0.644
tbx18 T-box 18 0.643
gli2a GLI-Kruppel family member GLI2a 0.642
jag2 jagged 2 0.636
osr1 odd-skipped related 1 (Drosophila) 0.600
evx1 even-skipped homeobox 1 0.575
med12 mediator of RNA polymerase II transcription, subunit 12 homolog 0.573
rag1 recombination activating gene 1 0.560
trpv6 transient receptor potential cation channel, subfamily V, member 6 0.556
hoxa9a homeo box A9a 0.549
pax6a paired box gene 6a 0.543
dlx3b distal-less homeobox gene 3b 0.540
tshb thyroid stimulating hormone, beta subunit 0.533
pax7a paired box gene 7a 0.529
hhex hematopoietically expressed homeobox 0.526
irx4b iroquois homeobox protein 4b 0.526
bmp2b bone morphogenetic protein 2b 0.515
myf5 myogenic factor 5 0.514
pou1f1 POU domain, class 1, transcription factor 1 0.509
lft1 lefty1 0.508
fezf2 FEZ family zinc finger 2 0.506
pitx2 paired-like homeodomain transcription factor 2 0.503
gdnf glial cell derived neurotrophic factor 0.480
tbx20 T-box 20 0.471
tbx16 T-box gene 16 0.436
lhx5 LIM homeobox 5 0.436
fn1 fibronectin 1 0.426
nkx2.5 NK2 transcription factor related 5 0.424
tcf7l2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.419
fzd8a frizzled homolog 8a 0.416
atoh1a atonal homolog 1a 0.416
zic1 zic family member 1 (odd-paired homolog, Drosophila) 0.409
col2a1a collagen type II, alpha-1a 0.400
gcm2 glial cells missing homolog 2 (Drosophila) 0.388
ptf1a pancreas specific transcription factor, 1a 0.385
etv2 ets variant gene 2 0.381
fzd7a frizzled homolog 7a 0.380
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.374
emx3 empty spiracles homeobox 3 0.371
foxg1a forkhead box G1a 0.364
esr1 estrogen receptor 1 0.363
sox19a SRY-box containing gene 19a 0.358
eomesa eomesodermin homolog a 0.352
sox9b SRY-box containing gene 9b 0.352
hoxd13a homeo box D13a 0.349
wnt4a wingless-type MMTV integration site family, member 4a 0.348
tbx5a T-box 5a 0.345
hmx3 homeo box (H6 family) 3 0.340
fgfr3 fibroblast growth factor receptor 3 0.340
hoxb3a homeo box B3a 0.339
axin2 axin 2 (conductin, axil) 0.332
olig2 oligodendrocyte lineage transcription factor 2 0.332
clock clock 0.331
smo smoothened homolog (Drosophila) 0.324
jam3b junctional adhesion molecule 3b 0.323
isl1 islet1 0.320
nr2e3 nuclear receptor subfamily 2, group E, member 3 0.316
myog myogenin 0.314
runx2a runt-related transcription factor 2a 0.312
mafl v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein L 0.305
foxp2 forkhead box P2 0.305
notch1b notch homolog 1b 0.298
cbx5 chromobox homolog 5 (HP1 alpha homolog, Drosophila) 0.298
dlb deltaB 0.297
tal1 T-cell acute lymphocytic leukemia 1 0.294
raraa retinoic acid receptor, alpha a 0.291
mef2d myocyte enhancer factor 2d 0.290
pax9 paired box gene 9 0.289
hoxc9a homeo box C9a 0.287
hmgb3a high-mobility group box 3a 0.285
sema3aa semaphorin 3aa 0.284
ighz2 immunoglobulin heavy constant zeta2 0.284
mc2r melanocortin 2 receptor 0.281
hoxd11a homeo box D11a 0.278
sulf1 sulfatase 1 0.276
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Drosophila melanogaster
Name Description Probability Func Analog Organism
exd extradenticle 1.000
pan pangolin 0.997
Akt1 CG4006 gene product from transcript CG4006-RA 0.995
Fmr1 CG6203 gene product from transcript CG6203-RC 0.994
nmo nemo 0.994
hth homothorax 0.993
wg wingless 0.992
slmb supernumerary limbs 0.991
ftz-f1 ftz transcription factor 1 0.988
Cp190 Centrosomal protein 190kD 0.987
InR Insulin-like receptor 0.982
osa CG7467 gene product from transcript CG7467-RD 0.981
lwr lesswright 0.974
hep hemipterous 0.972
brm brahma 0.971
mor moira 0.970
MED15 Mediator complex subunit 15 0.968
kis kismet 0.967
Snr1 Snf5-related 1 0.956
trx trithorax 0.956
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.946
eyg eyegone 0.943
HLHm7 E(spl) region transcript m7 0.941
CkIIalpha Casein kinase II alpha subunit 0.941
Ubx Ultrabithorax 0.939
phl pole hole 0.934
Ras85D Ras oncogene at 85D 0.933
fru fruitless 0.933
Pc Polycomb 0.932
Pcaf CG4107 gene product from transcript CG4107-RA 0.931
ci cubitus interruptus 0.926
gro groucho 0.925
dm diminutive 0.919
CycA Cyclin A 0.917
E(spl) Enhancer of split 0.908
yki yorkie 0.902
numb CG3779 gene product from transcript CG3779-RB 0.902
klu klumpfuss 0.900
slp1 sloppy paired 1 0.877
Nrg Neuroglian 0.871
pb proboscipedia 0.852
lola longitudinals lacking 0.845
Rac1 CG2248 gene product from transcript CG2248-RA 0.831
os outstretched 0.831
EcR Ecdysone receptor 0.830
Dcr-2 Dicer-2 0.829
Antp Antennapedia 0.827
smt3 CG4494 gene product from transcript CG4494-RA 0.812
Sos Son of sevenless 0.812
ap apterous 0.802
Med Medea 0.802
jing CG9397 gene product from transcript CG9397-RI 0.800
dsx doublesex 0.785
Moe Moesin 0.782
osk oskar 0.772
sax saxophone 0.771
Sir2 CG5216 gene product from transcript CG5216-RA 0.771
N Notch 0.770
ara araucan 0.764
Egfr Epidermal growth factor receptor 0.762
SoxN SoxNeuro 0.760
Dl Delta 0.754
lea leak 0.751
shi shibire 0.751
TER94 CG2331 gene product from transcript CG2331-RA 0.743
Smr Smrter 0.743
vas vasa 0.739
Su(H) Suppressor of Hairless 0.738
abd-A abdominal A 0.738
hipk homeodomain interacting protein kinase 0.732
ctp cut up 0.729
Pka-C1 cAMP-dependent protein kinase 1 0.727
heph hephaestus 0.725
ed echinoid 0.724
Lk6 CG17342 gene product from transcript CG17342-RA 0.720
mus209 mutagen-sensitive 209 0.713
Rel Relish 0.712
dpp decapentaplegic 0.711
kay kayak 0.702
bin biniou 0.699
dnc dunce 0.690
CG4699 CG4699 gene product from transcript CG4699-RJ 0.685
Gug Grunge 0.680
key kenny 0.675
emc extra macrochaetae 0.674
sens senseless 0.667
Hrb27C Heterogeneous nuclear ribonucleoprotein at 27C 0.666
alphaTub67C alpha-Tubulin at 67C 0.665
Mef2 Myocyte enhancer factor 2 0.660
Pvr PDGF- and VEGF-receptor related 0.658
bowl brother of odd with entrails limited 0.656
Su(var)3-3 Suppressor of variegation 3-3 0.651
hkb huckebein 0.644
bs blistered 0.638
CaMKII Calcium/calmodulin-dependent protein kinase II 0.634
ebi CG4063 gene product from transcript CG4063-RA 0.632
por porcupine 0.632
MED17 Mediator complex subunit 17 0.630
sev sevenless 0.629
BRWD3 CG31132 gene product from transcript CG31132-RA 0.628
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Homo sapiens
Name Description Probability Func Analog Organism
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
RPD3 Rpd3p 0.983
YTA7 Yta7p 0.975
GLN3 Gln3p 0.963
GCN5 Gcn5p 0.963
URE2 Ure2p 0.958
SWI6 Swi6p 0.956
HOG1 Hog1p 0.953
LSM1 Lsm1p 0.925
RTF1 Rtf1p 0.923
SRB4 Srb4p 0.916
MSN2 Msn2p 0.915
RPT6 Rpt6p 0.897
CDC28 Cdc28p 0.896
AFT1 Aft1p 0.895
MKS1 Mks1p 0.892
RTG3 Rtg3p 0.892
NUP100 Nup100p 0.891
SIN3 Sin3p 0.888
ESA1 Esa1p 0.880
SNF5 Snf5p 0.874
YAP1 Yap1p 0.871
MET4 Met4p 0.857
SNF6 Snf6p 0.847
GAL11 Gal11p 0.840
ADA2 Ada2p 0.838
SPT15 Spt15p 0.821
RIM101 Rim101p 0.814
HSP78 Hsp78p 0.811
RXT2 Rxt2p 0.803
CTR9 Ctr9p 0.800
RGR1 Rgr1p 0.797
CTK3 Ctk3p 0.792
PGD1 Pgd1p 0.774
CYC8 Cyc8p 0.773
NRG1 Nrg1p 0.768
ROX3 Rox3p 0.767
MOT2 Mot2p 0.758
KSS1 Kss1p 0.756
SNF2 Snf2p 0.755
CLN2 Cln2p 0.750
SRB5 Srb5p 0.746
TPK1 Tpk1p 0.737
SDS3 Sds3p 0.729
CCR4 Ccr4p 0.726
MED6 Med6p 0.715
SWI1 Swi1p 0.687
CHD1 Chd1p 0.683
SPT8 Spt8p 0.683
ARG81 Arg81p 0.675
PHO23 Pho23p 0.661
CAT8 Cat8p 0.659
GIS1 Gis1p 0.659
KIN28 Kin28p 0.646
LEU3 Leu3p 0.638
VPS27 Vps27p 0.636
MIG1 Mig1p 0.621
SKN7 Skn7p 0.614
GRX4 Grx4p 0.610
HAP5 Hap5p 0.606
SWI3 Swi3p 0.604
HST1 Hst1p 0.602
FKH1 Fkh1p 0.601
SNT1 Snt1p 0.601
PCC1 Pcc1p 0.599
RAP1 Rap1p 0.592
PLC1 Plc1p 0.590
MED1 Med1p 0.582
SLT2 Slt2p 0.580
CLB6 Clb6p 0.569
PAT1 Pat1p 0.559
RTG1 Rtg1p 0.543
YKE2 Yke2p 0.541
FIG4 Fig4p 0.535
NOT5 Not5p 0.534
FKH2 Fkh2p 0.531
CKS1 Cks1p 0.530
GAL80 Gal80p 0.528
SET2 Set2p 0.522
SRB6 Srb6p 0.521
HDA1 Hda1p 0.502
NUP157 Nup157p 0.502
PSH1 Psh1p 0.501
AEP1 Aep1p 0.499
SIN4 Sin4p 0.497
SEF1 Sef1p 0.497
DCP2 Dcp2p 0.495
SSN3 Ssn3p 0.489
SET1 Set1p 0.489
CDC55 Cdc55p 0.488
DHH1 Dhh1p 0.487
CLB1 Clb1p 0.484
BDF1 Bdf1p 0.481
RAD52 Rad52p 0.481
TOR1 Tor1p 0.478
POP2 Pop2p 0.469
GAL4 Gal4p 0.460
THI3 Thi3p 0.459
DOT6 Dot6p 0.459
RSP5 Rsp5p 0.458
CSE2 Cse2p 0.453