The network for 'cell morphogenesis involved in differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cell morphogenesis involved in differentiation

The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.

Rattus norvegicus
Name Description Probability Func Analog Organism
Map2 microtubule-associated protein 2 0.717
Fgfr2 fibroblast growth factor receptor 2 0.709
Gria2 glutamate receptor, ionotropic, AMPA 2 0.538
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 0.493
Nrxn1 neurexin 1 0.488
Slc6a6 solute carrier family 6 (neurotransmitter transporter, taurine), member 6 0.480
Lin7b lin-7 homolog b (C. elegans) 0.469
Col12a1 collagen, type XII, alpha 1 0.415
Met met proto-oncogene 0.409
Myh9 myosin, heavy chain 9, non-muscle 0.396
Adrb1 adrenergic, beta-1-, receptor 0.394
Tpm3 tropomyosin 3, gamma 0.386
Klf6 Kruppel-like factor 6 0.386
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.382
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.381
Accn2 amiloride-sensitive cation channel 2, neuronal 0.344
Fgfr1 Fibroblast growth factor receptor 1 0.334
Gprc5c G protein-coupled receptor, family C, group 5, member C 0.331
Pacs1 phosphofurin acidic cluster sorting protein 1 0.326
Prrx1 paired related homeobox 1 0.320
Tgfbr2 transforming growth factor, beta receptor II 0.316
Galr3 galanin receptor 3 0.313
Acta2 smooth muscle alpha-actin 0.312
Isl1 ISL LIM homeobox 1 0.309
Lamc1 laminin, gamma 1 0.303
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.295
Hist1h1d histone cluster 1, H1d 0.274
Pfn1 profilin 1 0.274
Msn moesin 0.272
Tagln transgelin 0.271
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.270
Dchs1 dachsous 1 (Drosophila) 0.268
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.264
Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.260
Calcrl calcitonin receptor-like 0.249
Iqgap1 IQ motif containing GTPase activating protein 1 0.242
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.238
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 0.238
Myo1c myosin IC 0.237
Cadm1 cell adhesion molecule 1 0.235
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.235
Slc24a2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 0.229
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.224
Nr4a1 nuclear receptor subfamily 4, group A, member 1 0.215
Acan aggrecan 0.213
Grm5 glutamate receptor, metabotropic 5 0.210
Jak2 Janus kinase 2 0.207
Smad7 SMAD family member 7 0.205
P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 0.203
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.203
Gata6 GATA binding protein 6 0.202
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.202
Brunol5 bruno-like 5, RNA binding protein (Drosophila) 0.201
Dlgap3 discs, large (Drosophila) homolog-associated protein 3 0.200
Anxa2 annexin A2 0.199
Itgb1 integrin, beta 1 0.198
Nlgn2 neuroligin 2 0.197
Cyth3 cytohesin 3 0.195
Kcnb1 potassium voltage gated channel, Shab-related subfamily, member 1 0.194
Notch1 Notch homolog 1, translocation-associated (Drosophila) 0.194
Robo2 roundabout homolog 2 (Drosophila) 0.194
Lphn2 latrophilin 2 0.194
Cpd carboxypeptidase D 0.193
Gabrb1 gamma-aminobutyric acid (GABA) A receptor, beta 1 0.192
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.192
Stxbp2 syntaxin binding protein 2 0.191
Apc adenomatous polyposis coli 0.191
Prkch protein kinase C, eta 0.190
Sirpa signal-regulatory protein alpha 0.189
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 0.188
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.188
Ctnnd2 catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein) 0.187
Matk megakaryocyte-associated tyrosine kinase 0.187
Ptprs protein tyrosine phosphatase, receptor type, S 0.186
Ankrd1 ankyrin repeat domain 1 (cardiac muscle) 0.186
Mpeg1 macrophage expressed 1 0.185
Cnn1 calponin 1, basic, smooth muscle 0.183
Ryk receptor-like tyrosine kinase 0.178
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 0.178
Dlg4 discs, large homolog 4 (Drosophila) 0.176
Klc1 kinesin light chain 1 0.173
Nefm neurofilament, medium polypeptide 0.171
Tcf4 transcription factor 4 0.170
Rap1b RAP1B, member of RAS oncogene family 0.166
Pde4b phosphodiesterase 4B, cAMP specific 0.163
Tmod2 tropomodulin 2 0.162
Syp synaptophysin 0.162
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 0.161
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) 0.161
St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 0.158
Dlg1 discs, large homolog 1 (Drosophila) 0.157
Purb purine rich element binding protein B 0.155
Gdf11 growth differentiation factor 11 0.152
Arf6 ADP-ribosylation factor 6 0.150
Dlg3 discs, large homolog 3 (Drosophila) 0.149
Stk10 serine/threonine kinase 10 0.146
Pip4k2b phosphatidylinositol-5-phosphate 4-kinase, type II, beta 0.146
Ptprk protein tyrosine phosphatase, receptor type, K, extracellular region 0.146
Cltc clathrin, heavy chain (Hc) 0.145
Hspb1 heat shock protein 1 0.145
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
nhr-67 Protein NHR-67 0.915
egl-18 Protein EGL-18 0.894
unc-42 Protein UNC-42 0.886
pha-4 Protein PHA-4 0.848
unc-62 Protein UNC-62 0.814
syg-1 Protein SYG-1 0.762
let-60 Protein LET-60 0.723
pry-1 Protein PRY-1 0.718
daf-11 Protein DAF-11 0.718
hlh-2 Protein HLH-2 0.707
vab-3 Protein VAB-3 0.697
egl-46 Protein EGL-46 0.673
lin-17 Protein LIN-17 0.613
mig-2 Protein MIG-2 0.608
rig-6 Protein RIG-6 0.535
sem-5 Protein SEM-5 0.531
atg-2 Protein ATG-2 0.490
fkh-2 Protein FKH-2 0.475
cin-4 Protein CIN-4 0.460
hbl-1 Protein HBL-1 0.452
lin-12 Protein LIN-12 0.445
eor-1 Protein EOR-1 0.444
unc-104 Protein UNC-104 0.439
cam-1 Protein CAM-1 0.428
pat-6 Protein PAT-6 0.426
mab-5 Protein MAB-5 0.420
mig-38 Protein MIG-38 0.406
ifg-1 Protein IFG-1 0.399
K10C8.3 Protein K10C8.3 0.390
hlh-1 Protein HLH-1 0.377
ten-1 Protein TEN-1 0.375
rpn-2 Protein RPN-2 0.373
egl-27 Protein EGL-27 0.365
lsy-2 Protein LSY-2 0.330
apl-1 Protein APL-1 0.329
daf-3 Protein DAF-3 0.329
unc-52 Protein UNC-52 0.328
R90.1 Protein R90.1 0.311
ceh-20 Protein CEH-20 0.303
eya-1 Protein EYA-1 0.301
ceh-16 Protein CEH-16 0.299
egl-30 Protein EGL-30 0.298
nhr-34 Protein NHR-34 0.295
epn-1 Protein EPN-1 0.292
elt-6 Protein ELT-6 0.290
syd-9 Protein SYD-9 0.289
spt-5 Protein SPT-5 0.288
unc-73 Protein UNC-73 0.287
T28F4.1 Protein T28F4.1 0.286
ldb-1 Protein LDB-1 0.285
mig-5 Protein MIG-5 0.280
pxf-1 Protein PXF-1 0.275
flt-1 Protein FLT-1 0.274
ceh-27 Protein CEH-27 0.274
teg-4 Protein TEG-4 0.273
unc-70 Protein UNC-70 0.270
egl-13 Protein EGL-13 0.266
ttx-1 Protein TTX-1 0.257
olrn-1 Protein OLRN-1 0.253
syg-2 Protein SYG-2 0.249
pmp-3 Protein PMP-3 0.248
bar-1 Protein BAR-1 0.247
CELE_C38D4.1 Protein C38D4.1 0.244
ajm-1 Protein AJM-1 0.241
odr-3 Protein ODR-3 0.236
lin-23 Protein LIN-23 0.231
sdn-1 Protein SDN-1 0.230
spc-1 Protein SPC-1 0.230
unc-1 Protein UNC-1 0.228
sli-1 Protein SLI-1 0.226
gar-3 Protein GAR-3 0.224
mec-8 Protein MEC-8 0.223
egg-6 Protein EGG-6 0.221
pop-1 Protein POP-1 0.219
eat-6 Protein EAT-6 0.219
srgp-1 Protein SRGP-1 0.218
unc-43 Protein UNC-43 0.214
egl-36 Protein EGL-36 0.214
C11E4.6 Protein C11E4.6 0.213
mtr-4 Protein MTR-4 0.213
clh-5 Protein CLH-5 0.213
pat-3 Protein PAT-3 0.211
crm-1 Protein CRM-1 0.205
mep-1 Protein MEP-1 0.204
inx-13 Protein INX-13 0.199
hnd-1 Protein HND-1 0.198
lin-36 Protein LIN-36 0.197
unc-54 Protein UNC-54 0.196
R10E12.2 Protein R10E12.2 0.194
F38B6.6 Protein F38B6.6 0.193
egl-5 Protein EGL-5 0.187
zip-7 Protein ZIP-7 0.186
pkg-1 Protein PKG-1 0.180
M01A8.2 Protein M01A8.2 0.168
CELE_Y41E3.11 Protein Y41E3.11 0.168
cog-1 Protein COG-1 0.166
pept-3 Protein PEPT-3 0.166
egl-8 Protein EGL-8 0.166
sax-3 Protein SAX-3 0.163
ain-1 Protein AIN-1 0.163
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Danio rerio
Name Description Probability Func Analog Organism
lamc1 laminin, gamma 1 0.996
dla deltaA 0.993
shha sonic hedgehog a 0.992
pitx3 paired-like homeodomain transcription factor 3 0.991
gli1 GLI-Kruppel family member 1 0.991
alcama activated leukocyte cell adhesion molecule a 0.989
lhx2b LIM homeobox 2b 0.989
dag1 dystroglycan 1 0.986
foxn4 forkhead box N4 0.985
notch1a notch homolog 1a 0.983
tbx1 T-box 1 0.983
wnt10a wingless-type MMTV integration site family, member 10a 0.981
cxcr4b chemokine (C-X-C motif), receptor 4b 0.980
foxd3 forkhead box D3 0.979
dlb deltaB 0.979
alcamb activated leukocyte cell adhesion molecule b 0.975
dlx5a distal-less homeobox gene 5a 0.967
ascl1a achaete-scute complex-like 1a (Drosophila) 0.954
fgfr1a fibroblast growth factor receptor 1a 0.954
ptpra protein tyrosine phosphatase, receptor type, A 0.949
chd chordin 0.948
tgfb3 transforming growth factor, beta 3 0.945
cdh2 cadherin 2, neuronal 0.944
spry4 sprouty (Drosophila) homolog 4 0.940
nrp2b neuropilin 2b 0.930
prdm1a PR domain containing 1a, with ZNF domain 0.929
ptch2 patched 2 0.927
nes nestin 0.922
fgf8a fibroblast growth factor 8 a 0.920
evx1 even-skipped homeobox 1 0.913
frem3 Fras1 related extracellular matrix 3 0.911
hand2 heart and neural crest derivatives expressed transcript 2 0.910
atoh1a atonal homolog 1a 0.909
pcdh18b protocadherin 18b 0.904
fgfr4 fibroblast growth factor receptor 4 0.893
bmp2a bone morphogenetic protein 2a 0.888
her6 hairy-related 6 0.886
traf4a tnf receptor-associated factor 4a 0.879
hey1 hairy/enhancer-of-split related with YRPW motif 1 0.878
sox2 SRY-box containing gene 2 0.876
lama2 laminin, alpha 2 0.876
stmn2b stathmin-like 2b 0.875
robo3 roundabout homolog 3 0.874
igf1rb insulin-like growth factor 1b receptor 0.873
ptenb phosphatase and tensin homolog B (mutated in multiple advanced cancers 1) 0.864
neurog1 neurogenin 1 0.863
gata2a GATA-binding protein 2a 0.860
slc17a6b solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b 0.856
ntla no tail a 0.854
osr1 odd-skipped related 1 (Drosophila) 0.848
cntn2 contactin 2 0.842
olig2 oligodendrocyte lineage transcription factor 2 0.840
jag1b jagged 1b 0.838
lhx1a LIM homeobox 1a 0.836
otx1a orthodenticle homolog 1a 0.829
wnt11r wingless-type MMTV integration site family, member 11, related 0.827
tbx5a T-box 5a 0.825
flh floating head 0.823
pbx4 pre-B-cell leukemia transcription factor 4 0.822
dmd dystrophin 0.815
wnt8b wingless-type MMTV integration site family, member 8b 0.814
dact1 dapper homolog 1, antagonist of beta-catenin (xenopus) 0.813
fn1 fibronectin 1 0.811
irx4b iroquois homeobox protein 4b 0.807
boc brother of CDO 0.806
elavl3 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) 0.805
notch3 notch homolog 3 0.801
atoh7 atonal homolog 7 0.795
scn8aa sodium channel, voltage-gated, type VIII, alpha a 0.792
lamb2 laminin, beta 2 (laminin S) 0.786
prdm14 PR domain containing 14 0.786
pea3 ETS-domain transcription factor pea3 0.781
emx3 empty spiracles homeobox 3 0.780
osr2 odd-skipped related 2 (Drosophila) 0.779
rx3 retinal homeobox gene 3 0.768
foxg1a forkhead box G1a 0.768
disp1 dispatched homolog 1 (Drosophila) 0.767
ctnnb1 catenin (cadherin-associated protein), beta 1 0.765
rdh10a retinol dehydrogenase 10a 0.756
wnt2bb wingless-type MMTV integration site family, member 2Bb 0.754
dlc deltaC 0.753
fezf2 FEZ family zinc finger 2 0.744
neurod neurogenic differentiation 0.739
isl1 islet1 0.736
ephb4b eph receptor B4b 0.735
fgf3 fibroblast growth factor 3 0.735
pax6b paired box gene 6b 0.733
phox2a paired-like homeobox 2a 0.731
epha4b eph receptor A4b 0.725
gnrh3 gonadotropin-releasing hormone 3 0.723
mafba v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian) 0.715
lamb1a laminin, beta 1a 0.713
mpx myeloid-specific peroxidase 0.712
gro1 groucho 1 0.695
sim1a single-minded homolog 1a (Drosophila) 0.695
shhb sonic hedgehog b 0.695
wnt11 wingless-type MMTV integration site family, member 11 0.694
tuba1 tubulin, alpha 1 0.691
lhx5 LIM homeobox 5 0.687
tbx2b T-box 2b 0.681
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Drosophila melanogaster
Name Description Probability Func Analog Organism
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Homo sapiens
Name Description Probability Func Analog Organism
FYN FYN oncogene related to SRC, FGR, YES 1.000
EGFR epidermal growth factor receptor 1.000
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.999
FN1 fibronectin 1 0.999
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.999
FLNA filamin A, alpha 0.992
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.992
SMAD2 SMAD family member 2 0.990
CREBBP CREB binding protein 0.988
QKI quaking homolog, KH domain RNA binding (mouse) 0.983
FHL2 four and a half LIM domains 2 0.982
TP53 tumor protein p53 0.974
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.972
RB1 retinoblastoma 1 0.969
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.966
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.964
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.960
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.958
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 0.956
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.954
SMAD3 SMAD family member 3 0.949
ATXN1 ataxin 1 0.942
ABL1 c-abl oncogene 1, non-receptor tyrosine kinase 0.936
NCOR1 nuclear receptor corepressor 1 0.933
GSK3B glycogen synthase kinase 3 beta 0.932
AR androgen receptor 0.931
ATF2 activating transcription factor 2 0.901
HDAC1 histone deacetylase 1 0.896
RHOA ras homolog gene family, member A 0.893
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.845
LATS2 LATS, large tumor suppressor, homolog 2 (Drosophila) 0.840
TCF3 transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) 0.832
COL5A1 collagen, type V, alpha 1 0.826
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.824
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.816
SKI v-ski sarcoma viral oncogene homolog (avian) 0.812
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.812
MSN moesin 0.790
COL4A2 collagen, type IV, alpha 2 0.769
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.763
IGF1R insulin-like growth factor 1 receptor 0.759
JAG1 jagged 1 0.756
THBS1 thrombospondin 1 0.745
HDAC2 histone deacetylase 2 0.741
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.727
BCAR1 breast cancer anti-estrogen resistance 1 0.727
HSPG2 heparan sulfate proteoglycan 2 0.726
DHX30 DEAH (Asp-Glu-Ala-His) box polypeptide 30 0.722
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.720
EP300 E1A binding protein p300 0.720
JUN jun proto-oncogene 0.709
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.709
MAPT microtubule-associated protein tau 0.706
SKIL SKI-like oncogene 0.693
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.692
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.683
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.675
NCAM1 neural cell adhesion molecule 1 0.674
ATN1 atrophin 1 0.670
ANXA2 annexin A2 0.670
TCF4 transcription factor 4 0.667
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.663
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.660
DST dystonin 0.656
SOS1 son of sevenless homolog 1 (Drosophila) 0.651
APC adenomatous polyposis coli 0.643
MPRIP myosin phosphatase Rho interacting protein 0.642
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.640
SOX11 SRY (sex determining region Y)-box 11 0.638
HDAC4 histone deacetylase 4 0.633
LAMB1 laminin, beta 1 0.629
COL1A2 collagen, type I, alpha 2 0.619
NCOA1 nuclear receptor coactivator 1 0.613
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.610
MYOD1 myogenic differentiation 1 0.586
ILK integrin-linked kinase 0.580
FBLN1 fibulin 1 0.574
ITSN1 intersectin 1 (SH3 domain protein) 0.568
SMAD4 SMAD family member 4 0.567
MAPK8 mitogen-activated protein kinase 8 0.566
COL5A2 collagen, type V, alpha 2 0.564
PLXNB1 plexin B1 0.562
CAV1 caveolin 1, caveolae protein, 22kDa 0.561
ACTN1 actinin, alpha 1 0.557
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.555
GRB2 growth factor receptor-bound protein 2 0.554
ZMYND11 zinc finger, MYND-type containing 11 0.542
TAL1 T-cell acute lymphocytic leukemia 1 0.538
DAB2 disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) 0.535
ESR1 estrogen receptor 1 0.533
BMP7 bone morphogenetic protein 7 0.529
NOTCH3 notch 3 0.528
COL4A1 collagen, type IV, alpha 1 0.525
SMAD1 SMAD family member 1 0.524
FGFR2 fibroblast growth factor receptor 2 0.519
EZR ezrin 0.513
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.513
SIRT1 sirtuin 1 0.510
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.510
EGR1 early growth response 1 0.509
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Mus musculus
Name Description Probability Func Analog Organism
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism