The network for 'salivary gland development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

salivary gland development

The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.

Rattus norvegicus
Name Description Probability Func Analog Organism
Edn1 endothelin 1 0.183
Prkcd protein kinase C, delta 0.170
Nfib nuclear factor I/B 0.166
Igfbp5 insulin-like growth factor binding protein 5 0.156
Bcl2 B-cell CLL/lymphoma 2 0.150
Mcam melanoma cell adhesion molecule 0.141
Cd4 Cd4 molecule 0.138
Erbb3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.118
Fgfr2 fibroblast growth factor receptor 2 0.110
Tgfbr2 transforming growth factor, beta receptor II 0.103
Pik3ap1 phosphoinositide-3-kinase adaptor protein 1 0.100
Mpp3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.100
Rab10 RAB10, member RAS oncogene family 0.099
Col12a1 collagen, type XII, alpha 1 0.098
Bin1 bridging integrator 1 0.097
Fut1 fucosyltransferase 1 0.097
Marcks myristoylated alanine rich protein kinase C substrate 0.093
Cd14 CD14 molecule 0.089
Snai1 snail homolog 1 (Drosophila) 0.088
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.086
Socs3 suppressor of cytokine signaling 3 0.082
Cbl Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.080
Il1r1 interleukin 1 receptor, type I 0.079
Foxs1 forkhead box S1 0.072
Pftk1 PFTAIRE protein kinase 1 0.072
Acvr1 activin A receptor, type I 0.069
Robo1 roundabout homolog 1 (Drosophila) 0.067
Notch2 Notch homolog 2 (Drosophila) 0.067
Elf1 E74-like factor 1 0.067
Olfml2b olfactomedin-like 2B 0.065
Prf1 perforin 1 (pore forming protein) 0.065
Ptprc protein tyrosine phosphatase, receptor type, C 0.065
Thbd thrombomodulin 0.065
Sirpa signal-regulatory protein alpha 0.064
Apoe apolipoprotein E 0.064
Slc15a3 solute carrier family 15, member 3 0.064
Mllt4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.063
Fgfr1 Fibroblast growth factor receptor 1 0.062
Slit3 slit homolog 3 (Drosophila) 0.061
Col5a1 collagen, type V, alpha 1 0.061
Erbb4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.061
Prp15 proline-rich protein 15 0.059
Clec11a C-type lectin domain family 11, member a 0.058
Lamc1 laminin, gamma 1 0.058
Plau plasminogen activator, urokinase 0.058
Ptpn14 protein tyrosine phosphatase, non-receptor type 14 0.058
Rab3il1 RAB3A interacting protein (rabin3)-like 1 0.057
Rabac1 Rab acceptor 1 (prenylated) 0.056
C1qtnf6 C1q and tumor necrosis factor related protein 6 0.054
Slit1 slit homolog 1 (Drosophila) 0.054
Kit v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 0.054
Cd37 CD37 molecule 0.054
Lcp1 lymphocyte cytosolic protein 1 0.053
Tcrb T-cell receptor beta chain 0.053
Ocln occludin 0.052
Il1b interleukin 1 beta 0.052
Ptprs protein tyrosine phosphatase, receptor type, S 0.051
Cd86 CD86 molecule 0.051
Gnrhr gonadotropin releasing hormone receptor 0.051
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.051
Ccdc102a coiled-coil domain containing 102A 0.050
Stat6 signal transducer and activator of transcription 6 0.050
Muc1 mucin 1, cell surface associated 0.050
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A 0.050
Plek pleckstrin 0.050
Pawr PRKC, apoptosis, WT1, regulator 0.050
Bmp3 bone morphogenetic protein 3 0.049
Ptpn18 protein tyrosine phosphatase, non-receptor type 18 0.048
Myo1f myosin IF 0.048
Mras muscle RAS oncogene homolog 0.048
Gna11 guanine nucleotide binding protein, alpha 11 0.048
Ap2a1 adaptor-related protein complex 2, alpha 1 subunit 0.048
Ptch1 patched homolog 1 (Drosophila) 0.047
Gdf11 growth differentiation factor 11 0.047
Myo1g myosin IG 0.047
Ehf ets homologous factor 0.047
Galntl1 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1 0.047
Epas1 endothelial PAS domain protein 1 0.047
Msn moesin 0.046
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide) 0.046
Mobkl2a MOB1, Mps One Binder kinase activator-like 2A (yeast) 0.045
Prrx1 paired related homeobox 1 0.045
Amph amphiphysin 0.045
Sstr4 somatostatin receptor 4 0.045
Slc2a13 solute carrier family 2 (facilitated glucose transporter), member 13 0.045
Pik3cd phosphoinositide-3-kinase, catalytic, delta polypeptide 0.045
Mpp2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) 0.045
Laptm5 lysosomal protein transmembrane 5 0.044
Esr1 estrogen receptor 1 0.044
Axl Axl receptor tyrosine kinase 0.044
Elavl4 ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D) 0.043
Igh-6 immunoglobulin heavy chain 6 0.043
Il2rg interleukin 2 receptor, gamma 0.043
Utrn utrophin 0.043
Tcfe2a transcription factor E2a 0.043
Inpp5d inositol polyphosphate-5-phosphatase D 0.042
LOC690418 similar to Acidic proline-rich protein PRP25 precursor 0.042
Kl Klotho 0.042
Map3k3 mitogen activated protein kinase kinase kinase 3 0.042
Gata6 GATA binding protein 6 0.042
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
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Drosophila melanogaster
Name Description Probability Func Analog Organism
LanB2 Laminin B2 0.987
mew multiple edematous wings 0.957
wb wing blister 0.927
stumps CG31317 gene product from transcript CG31317-RC 0.902
wg wingless 0.882
ush u-shaped 0.880
fz2 frizzled 2 0.856
E(spl) Enhancer of split 0.819
hkb huckebein 0.803
tin tinman 0.801
twi twist 0.794
HLHmbeta E(spl) region transcript mbeta 0.769
Egfr Epidermal growth factor receptor 0.759
sli slit 0.748
EcR Ecdysone receptor 0.724
Nrx-IV Neurexin IV 0.721
NetB Netrin-B 0.707
Fas2 Fasciclin 2 0.697
byn brachyenteron 0.673
nej nejire 0.668
lea leak 0.666
Rala Ras-related protein 0.650
fkh fork head 0.636
drpr draper 0.633
bin biniou 0.633
sno strawberry notch 0.610
aop anterior open 0.609
HLHm5 E(spl) region transcript m5 0.608
Wnt5 Wnt oncogene analog 5 0.591
ci cubitus interruptus 0.589
betaTub60D beta-Tubulin at 60D 0.585
sns sticks and stones 0.568
Rac1 CG2248 gene product from transcript CG2248-RA 0.565
brk brinker 0.564
Src42A Src oncogene at 42A 0.551
LanB1 CG7123 gene product from transcript CG7123-RA 0.548
shg shotgun 0.540
HLHmdelta E(spl) region transcript mdelta 0.533
abd-A abdominal A 0.531
B52 CG10851 gene product from transcript CG10851-RB 0.527
robo roundabout 0.523
zfh1 Zn finger homeodomain 1 0.515
slp1 sloppy paired 1 0.512
babo baboon 0.508
H Hairless 0.508
dpp decapentaplegic 0.505
ths thisbe 0.494
Nc Nedd2-like caspase 0.476
insc inscuteable 0.466
Six4 CG3871 gene product from transcript CG3871-RA 0.458
east enhanced adult sensory threshold 0.455
gcm glial cells missing 0.454
Alk CG8250 gene product from transcript CG8250-RA 0.439
Rho1 CG8416 gene product from transcript CG8416-RB 0.438
jing CG9397 gene product from transcript CG9397-RI 0.435
arm armadillo 0.433
LysE Lysozyme E 0.428
HLHm7 E(spl) region transcript m7 0.426
lola longitudinals lacking 0.415
vvl ventral veins lacking 0.415
vnd ventral nervous system defective 0.402
pzg putzig 0.389
dlp dally-like 0.388
slou slouch 0.381
unc-5 CG8166 gene product from transcript CG8166-RA 0.379
edl ETS-domain lacking 0.374
puc puckered 0.370
garz gartenzwerg 0.369
mam mastermind 0.367
htl heartless 0.362
fng fringe 0.356
MED24 Mediator complex subunit 24 0.355
Sas Sialic acid phosphate synthase 0.351
srp serpent 0.349
Nf-YC Nuclear factor Y-box C 0.348
Cdc42 CG12530 gene product from transcript CG12530-RA 0.346
CG4822 CG4822 gene product from transcript CG4822-RB 0.334
JIL-1 CG6297 gene product from transcript CG6297-RA 0.332
LysB Lysozyme B 0.332
Gprk2 G protein-coupled receptor kinase 2 0.318
CG14005 CG14005 gene product from transcript CG14005-RA 0.314
nkd naked cuticle 0.313
CG4328 CG4328 gene product from transcript CG4328-RB 0.311
Cad99C CG31009 gene product from transcript CG31009-RB 0.307
otk off-track 0.307
Cat Catalase 0.307
SoxN SoxNeuro 0.305
jumu jumeau 0.304
Atg1 Autophagy-specific gene 1 0.304
LIMK1 LIM-kinase1 0.297
lbe ladybird early 0.288
CG14869 CG14869 gene product from transcript CG14869-RB 0.283
eve even skipped 0.281
jar jaguar 0.279
plexB plexin B 0.276
HLHmgamma E(spl) region transcript mgamma 0.275
lbl ladybird late 0.273
gsb gooseberry 0.272
bsk basket 0.269
os outstretched 0.266
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Homo sapiens
Name Description Probability Func Analog Organism
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.886
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.365
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.237
FGFR2 fibroblast growth factor receptor 2 0.174
FYN FYN oncogene related to SRC, FGR, YES 0.154
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.154
EGFR epidermal growth factor receptor 0.123
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.102
FLNA filamin A, alpha 0.081
FN1 fibronectin 1 0.076
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 0.055
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.053
FGF1 fibroblast growth factor 1 (acidic) 0.050
FGFR1 fibroblast growth factor receptor 1 0.046
NRP1 neuropilin 1 0.043
PLEC plectin 0.041
KDR kinase insert domain receptor (a type III receptor tyrosine kinase) 0.039
JUP junction plakoglobin 0.034
HSPG2 heparan sulfate proteoglycan 2 0.034
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.033
PTPRJ protein tyrosine phosphatase, receptor type, J 0.033
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.030
VEGFA vascular endothelial growth factor A 0.029
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide) 0.024
PSEN1 presenilin 1 0.020
LYN v-yes-1 Yamaguchi sarcoma viral related oncogene homolog 0.019
LCK lymphocyte-specific protein tyrosine kinase 0.017
PDIA3 protein disulfide isomerase family A, member 3 0.016
DVL3 dishevelled, dsh homolog 3 (Drosophila) 0.016
ITGAV integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) 0.015
THBS1 thrombospondin 1 0.015
NOTCH3 notch 3 0.014
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.014
SYK spleen tyrosine kinase 0.014
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) 0.013
ENG endoglin 0.013
PTPRC protein tyrosine phosphatase, receptor type, C 0.012
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.012
LAMB1 laminin, beta 1 0.012
MEOX2 mesenchyme homeobox 2 0.012
FHL2 four and a half LIM domains 2 0.011
NOTCH1 notch 1 0.011
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Mus musculus
Name Description Probability Func Analog Organism
Fgfr2 fibroblast growth factor receptor 2 0.996
Lamc1 laminin, gamma 1 0.945
Trp63 transformation related protein 63 0.942
Robo1 roundabout homolog 1 (Drosophila) 0.938
Vegfa vascular endothelial growth factor A 0.912
Dvl2 dishevelled 2, dsh homolog (Drosophila) 0.909
Ntn1 netrin 1 0.906
Pax3 paired box gene 3 0.900
Hspg2 perlecan (heparan sulfate proteoglycan 2) 0.898
Gli3 GLI-Kruppel family member GLI3 0.851
Pdgfrb platelet derived growth factor receptor, beta polypeptide 0.849
Vangl2 vang-like 2 (van gogh, Drosophila) 0.843
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.776
Plcg1 phospholipase C, gamma 1 0.772
Ptgs2 prostaglandin-endoperoxide synthase 2 0.740
Mmp9 matrix metallopeptidase 9 0.739
Notch2 Notch gene homolog 2 (Drosophila) 0.730
Nog noggin 0.724
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.715
Nrp1 neuropilin 1 0.706
Ptk2 PTK2 protein tyrosine kinase 2 0.691
Ddr2 discoidin domain receptor family, member 2 0.691
Egfr epidermal growth factor receptor 0.685
Csf1 colony stimulating factor 1 (macrophage) 0.673
Sox2 SRY-box containing gene 2 0.657
Itgb3 integrin beta 3 0.657
Bmp4 bone morphogenetic protein 4 0.651
Shh sonic hedgehog 0.644
Tcf21 transcription factor 21 0.628
Ptk7 PTK7 protein tyrosine kinase 7 0.620
Fgf10 fibroblast growth factor 10 0.617
Plau plasminogen activator, urokinase 0.608
Pcsk5 proprotein convertase subtilisin/kexin type 5 0.607
Lama5 laminin, alpha 5 0.596
Vangl1 vang-like 1 (van gogh, Drosophila) 0.594
Ctnnb1 catenin (cadherin associated protein), beta 1 0.587
Itga3 integrin alpha 3 0.567
Gli2 GLI-Kruppel family member GLI2 0.512
Tbx2 T-box 2 0.496
Slit2 slit homolog 2 (Drosophila) 0.495
Dmd dystrophin, muscular dystrophy 0.486
Kdr kinase insert domain protein receptor 0.485
Flt4 FMS-like tyrosine kinase 4 0.432
Rarg retinoic acid receptor, gamma 0.429
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.401
Tbx3 T-box 3 0.394
Ar androgen receptor 0.392
Edaradd EDAR (ectodysplasin-A receptor)-associated death domain 0.391
Il10 interleukin 10 0.390
Pdgfra platelet derived growth factor receptor, alpha polypeptide 0.386
Slit3 slit homolog 3 (Drosophila) 0.378
Il4 interleukin 4 0.371
Gdnf glial cell line derived neurotrophic factor 0.355
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.345
Tgfb2 transforming growth factor, beta 2 0.335
Src Rous sarcoma oncogene 0.333
Alx4 aristaless-like homeobox 4 0.332
Lamb1 laminin B1 0.330
Nos2 nitric oxide synthase 2, inducible 0.328
Igh immunoglobulin heavy chain complex 0.327
Fgfr4 fibroblast growth factor receptor 4 0.313
Ret ret proto-oncogene 0.307
Dll1 delta-like 1 (Drosophila) 0.299
Notch1 Notch gene homolog 1 (Drosophila) 0.297
Ikzf1 IKAROS family zinc finger 1 0.291
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.289
Fgfr1 fibroblast growth factor receptor 1 0.285
Hoxa13 homeobox A13 0.284
Fgf7 fibroblast growth factor 7 0.284
Ror1 receptor tyrosine kinase-like orphan receptor 1 0.265
Tlx3 T-cell leukemia, homeobox 3 0.262
Rara retinoic acid receptor, alpha 0.257
Tnf tumor necrosis factor 0.256
Smad6 MAD homolog 6 (Drosophila) 0.252
Lhx1 LIM homeobox protein 1 0.244
Col4a2 collagen, type IV, alpha 2 0.243
Nos3 nitric oxide synthase 3, endothelial cell 0.242
Il6st interleukin 6 signal transducer 0.240
Jag1 jagged 1 0.238
Nkx2-3 NK2 transcription factor related, locus 3 (Drosophila) 0.235
Hoxa11 homeobox A11 0.234
Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b 0.231
Foxa2 forkhead box A2 0.227
Edar ectodysplasin-A receptor 0.222
Gata4 GATA binding protein 4 0.221
Gab1 growth factor receptor bound protein 2-associated protein 1 0.218
Zeb1 zinc finger E-box binding homeobox 1 0.216
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.211
Rgnef Rho-guanine nucleotide exchange factor 0.210
Ror2 receptor tyrosine kinase-like orphan receptor 2 0.203
Epha4 Eph receptor A4 0.199
Lama1 laminin, alpha 1 0.195
Dcc deleted in colorectal carcinoma 0.194
Dvl1 dishevelled, dsh homolog 1 (Drosophila) 0.192
Trp73 transformation related protein 73 0.191
Lama3 laminin, alpha 3 0.187
Hoxd13 homeobox D13 0.184
Lama4 laminin, alpha 4 0.176
Dvl3 dishevelled 3, dsh homolog (Drosophila) 0.175
Meox2 mesenchyme homeobox 2 0.172
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism