The network for 'response to alkaloid' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to alkaloid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.

Rattus norvegicus
Name Description Probability Func Analog Organism
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.671
Il1r1 interleukin 1 receptor, type I 0.630
Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) 0.616
Chrna4 cholinergic receptor, nicotinic, alpha 4 0.612
Psp parotid secretory protein 0.523
Htr2c 5-hydroxytryptamine (serotonin) receptor 2C 0.479
Hrh2 histamine receptor H 2 0.464
Cxcl2 chemokine (C-X-C motif) ligand 2 0.392
Slc18a3 solute carrier family 18 (vesicular acetylcholine), member 3 0.382
Lim2 lens intrinsic membrane protein 2 0.369
Agtr1a angiotensin II receptor, type 1a 0.365
Slco2b1 solute carrier organic anion transporter family, member 2b1 0.340
Tnf tumor necrosis factor (TNF superfamily, member 2) 0.340
RT1-Ba RT1 class II, locus Ba 0.334
Neurl3 neuralized homolog 3 (Drosophila) 0.333
Cxcl10 chemokine (C-X-C motif) ligand 10 0.332
LOC60591 calcium-activated potassium channel beta subunit 0.326
Egr2 early growth response 2 0.320
Cxcl1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.319
Akr1c18 aldo-keto reductase family 1, member C18 0.303
Cacng5 calcium channel, voltage-dependent, gamma subunit 5 0.302
Egr1 early growth response 1 0.293
Oprm1 opioid receptor, mu 1 0.290
Ctsj cathepsin J 0.286
Gng7 guanine nucleotide binding protein (G protein), gamma 7 0.282
Col10a1 collagen, type X, alpha 1 0.280
Mog myelin oligodendrocyte glycoprotein 0.276
Fos FBJ osteosarcoma oncogene 0.252
Star steroidogenic acute regulatory protein 0.248
Gstm1 glutathione S-transferase mu 1 0.247
Cmklr1 chemokine-like receptor 1 0.247
Socs3 suppressor of cytokine signaling 3 0.246
Slc14a2 solute carrier family 14 (urea transporter), member 2 0.246
Pla2g2c phospholipase A2, group IIC 0.245
Mag myelin-associated glycoprotein 0.242
Calca calcitonin-related polypeptide alpha 0.242
Loxl1 lysyl oxidase-like 1 0.241
Junb jun B proto-oncogene 0.241
Rgs8 regulator of G-protein signaling 8 0.241
Zfp36 zinc finger protein 36 0.240
Vip vasoactive intestinal peptide 0.240
Gfra2 GDNF family receptor alpha 2 0.239
Cx3cr1 chemokine (C-X3-C motif) receptor 1 0.236
Dio2 deiodinase, iodothyronine, type II 0.233
Ugt2b7 UDP glucuronosyltransferase 2 family, polypeptide B7 0.233
Accn2 amiloride-sensitive cation channel 2, neuronal 0.231
Hpcal4 hippocalcin-like 4 0.226
Ar androgen receptor 0.226
Ins2 insulin 2 0.225
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 0.224
Grin1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.221
Scn4a sodium channel, voltage-gated, type IV, alpha subunit 0.220
Atxn1 ataxin 1 0.219
Dnase1l3 deoxyribonuclease 1-like 3 0.207
Prkcg protein kinase C, gamma 0.206
Foxe1 forkhead box E1 (thyroid transcription factor 2) 0.203
Oxtr oxytocin receptor 0.203
Ccl11 chemokine (C-C motif) ligand 11 0.202
Plau plasminogen activator, urokinase 0.201
Flt1 FMS-related tyrosine kinase 1 0.201
Trhr2 thyrotropin releasing hormone receptor 2 0.200
Omp olfactory marker protein 0.199
Avpr1b arginine vasopressin receptor 1B 0.197
Inhba inhibin beta-A 0.196
Tbx2 T-box 2 0.196
Gria1 glutamate receptor, ionotropic, AMPA 1 0.185
Mchr1 melanin-concentrating hormone receptor 1 0.185
Kl Klotho 0.185
Col3a1 collagen, type III, alpha 1 0.182
Foxi2 forkhead box I2 0.179
Tpbpa trophoblast specific protein alpha 0.177
Hnmt histamine N-methyltransferase 0.176
Prlhr prolactin releasing hormone receptor 0.176
Sstr1 somatostatin receptor 1 0.176
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.175
Ccl20 chemokine (C-C motif) ligand 20 0.175
Hsd17b6 hydroxysteroid (17-beta) dehydrogenase 6 0.175
Htr7 5-hydroxytryptamine (serotonin) receptor 7 0.174
Cpb1 carboxypeptidase B1 (tissue) 0.173
Nr4a3 nuclear receptor subfamily 4, group A, member 3 0.173
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 0.172
Grm1 glutamate receptor, metabotropic 1 0.170
Dlg4 discs, large homolog 4 (Drosophila) 0.169
F2rl1 coagulation factor II (thrombin) receptor-like 1 0.168
Pmfbp1 polyamine modulated factor 1 binding protein 1 0.168
Teddm1 transmembrane epididymal protein 1 0.168
Cmtm2a CKLF-like MARVEL transmembrane domain containing 2A 0.165
Cxcl16 chemokine (C-X-C motif) ligand 16 0.164
Klk1c10 T-kininogenase 0.164
Hck hemopoietic cell kinase 0.164
Serpina3k serine (or cysteine) peptidase inhibitor, clade A, member 3K 0.163
Cgm4 carcinoembryonic antigen gene family 4 0.161
Klk1c10l2 kallikrein 1-related peptidase c10-like 2 0.161
Cd46 CD46 molecule, complement regulatory protein 0.161
Fgf2 fibroblast growth factor 2 0.161
Shank2 SH3 and multiple ankyrin repeat domains 2 0.160
Fev FEV (ETS oncogene family) 0.159
Gabrg1 gamma-aminobutyric acid (GABA) A receptor, gamma 1 0.159
Ptgs2 prostaglandin-endoperoxide synthase 2 0.159
Ptafr platelet-activating factor receptor 0.158
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
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Danio rerio
Name Description Probability Func Analog Organism
epas1b endothelial PAS domain protein 1b 0.824
gcm2 glial cells missing homolog 2 (Drosophila) 0.802
dab1a disabled homolog 1a (Drosophila) 0.608
drd2a dopamine receptor D2a 0.587
drd2b dopamine receptor D2b 0.516
drd3 dopamine receptor D3 0.492
per2 period homolog 2 (Drosophila) 0.488
pou4f2 POU domain, class 4, transcription factor 2 0.461
drd1 dopamine receptor D1 0.431
cx39.9 connexin 39.9 0.422
reln reelin 0.417
nadl1.2 neural adhesion molecule L1.2 0.411
uts1 urotensin 1 0.404
myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha 0.398
wnt9b wingless-type MMTV integration site family, member 9B 0.398
ghrb growth hormone receptor b 0.384
efna5b ephrin A5b 0.357
ogg1 8-oxoguanine DNA glycosylase 0.350
ripk2 receptor-interacting serine-threonine kinase 2 0.331
acvr2a activin receptor IIa 0.318
mc4r melanocortin 4 receptor 0.315
bdnf brain-derived neurotrophic factor 0.285
pth2 parathyroid hormone 2 0.282
ryr2a ryanodine receptor 2a (cardiac) 0.277
atp1b2a ATPase, Na+/K+ transporting, beta 2a polypeptide 0.274
bcl2 B-cell leukemia/lymphoma 2 0.269
wnt10a wingless-type MMTV integration site family, member 10a 0.268
foxa forkhead box A sequence 0.265
tac1 tachykinin 1 0.264
pdlim3b PDZ and LIM domain 3b 0.259
mef2d myocyte enhancer factor 2d 0.259
cx36.7 connexin 36.7 0.234
ptprf protein tyrosine phosphatase, receptor type, F 0.230
midn midnolin 0.227
slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.225
rc3 rabconnectin 3 0.224
fos v-fos FBJ murine osteosarcoma viral oncogene homolog 0.224
ncam2 neural cell adhesion molecule 2 0.210
mxi1 max interacting protein 0.210
mt2 metallothionein 2 0.201
hcrt hypocretin (orexin) neuropeptide precursor 0.187
trip13 thyroid hormone receptor interactor 13 0.187
gja3 gap junction protein, alpha 3 0.186
nlgn1 neuroligin 1 0.185
duox dual oxidase 0.184
kctd15a potassium channel tetramerisation domain containing 15a 0.184
unc5c unc-5 homolog C (C. elegans) 0.182
rag1 recombination activating gene 1 0.179
pomt2 protein-O-mannosyltransferase 2 0.178
vdra vitamin D receptor a 0.176
drd2l dopamine receptor D2 like 0.176
stc1l stanniocalcin 1, like 0.174
cel.1 carboxyl ester lipase, tandem duplicate 1 0.169
furina furin (paired basic amino acid cleaving enzyme) a 0.163
fhla four and a half LIM domains a 0.162
nr4a2b nuclear receptor subfamily 4, group A, member 2b 0.161
pcp4a Purkinje cell protein 4a 0.160
adipor1a adiponectin receptor 1a 0.153
csnk1db casein kinase 1, delta b 0.153
prdm16 PR domain containing 16 0.151
gins2 GINS complex subunit 2 0.151
lmo1 LIM domain only 1 0.146
mbnl2 muscleblind-like 2 (Drosophila) 0.144
oxtl oxytocin-like 0.144
tm4sf4 transmembrane 4 L six family member 4 0.141
rhag Rhesus blood group-associated glycoprotein 0.141
zgc:92903 zgc:92903 0.140
myhz2 myosin, heavy polypeptide 2, fast muscle specific 0.140
fmr1 fragile X mental retardation 1 0.137
esr1 estrogen receptor 1 0.133
cldnk claudin k 0.133
ela3l elastase 3 like 0.131
cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.130
odz4 odd Oz/ten-m homolog 4 0.129
chrm2a cholinergic receptor, muscarinic 2a 0.128
th tyrosine hydroxylase 0.126
ptprk protein tyrosine phosphatase, receptor type, K 0.125
ghra growth hormone receptor a 0.124
bcl2l1 bcl2-like 1 0.121
si:ch211-209p5.2 si:ch211-209p5.2 0.119
ascl1a achaete-scute complex-like 1a (Drosophila) 0.119
ctrb1 chymotrypsinogen B1 0.118
esrrga estrogen-related receptor gamma a 0.116
esr2a estrogen receptor 2a 0.116
spg11 spastic paraplegia 11 0.114
lpin1 lipin 1 0.114
foxp2 forkhead box P2 0.114
bmp7b bone morphogenetic protein 7b 0.113
ldb1a LIM-domain binding factor 1a 0.113
barhl1.1 BarH-like 1.1 0.113
pola2 polymerase (DNA directed), alpha 2 0.112
runx2a runt-related transcription factor 2a 0.111
barhl1.2 BarH-like 1.2 0.110
gdnf glial cell derived neurotrophic factor 0.109
tnnc1a troponin C type 1a (slow) 0.106
mao monoamine oxidase 0.106
ctsz cathepsin Z 0.106
ppp1r12a protein phosphatase 1, regulatory (inhibitor) subunit 12A 0.106
zgc:110343 zgc:110343 0.104
zgc:77395 zgc:77395 0.104
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Drosophila melanogaster
Name Description Probability Func Analog Organism
Tbh Tyramine beta hydroxylase 0.962
NPFR1 neuropeptide F receptor 0.423
mei-9 meiotic 9 0.381
Rdl Resistant to dieldrin 0.368
mus205 mutagen-sensitive 205 0.322
foxo forkhead box, sub-group O 0.294
CG42629 CG42629 gene product from transcript CG42629-RB 0.281
CG12672 CG12672 gene product from transcript CG12672-RA 0.280
Poxn Pox neuro 0.272
Mekk1 CG7717 gene product from transcript CG7717-RB 0.222
rad50 CG6339 gene product from transcript CG6339-RD 0.211
Cyp12a4 CG6042 gene product from transcript CG6042-RA 0.199
norpA no receptor potential A 0.196
CG13253 CG13253 gene product from transcript CG13253-RB 0.189
Cat Catalase 0.184
vri vrille 0.172
Smc5 CG32438 gene product from transcript CG32438-RE 0.167
jeb jelly belly 0.161
Or35a Odorant receptor 35a 0.159
mus304 mutagen-sensitive 304 0.157
Brca2 Breast cancer 2, early onset homolog 0.145
para paralytic 0.141
Ugt35a UDP-glycosyltransferase 35a 0.135
RecQ5 homolog of RecQ 0.134
CG9986 CG9986 gene product from transcript CG9986-RA 0.124
Cyp6a21 CG10247 gene product from transcript CG10247-RA 0.120
Or83c Odorant receptor 83c 0.117
Cyp28d1 CG10833 gene product from transcript CG10833-RA 0.115
JhI-26 Juvenile hormone-inducible protein 26 0.109
Spf45 CG17540 gene product from transcript CG17540-RB 0.106
Ac78C Adenylyl cyclase 78C 0.105
Or42b Odorant receptor 42b 0.101
Cyp6a23 CG10242 gene product from transcript CG10242-RA 0.097
mus201 mutagen-sensitive 201 0.093
S6k RPS6-p70-protein kinase 0.091
D2R Dopamine 2-like receptor 0.088
Pkc98E Protein C kinase 98E 0.088
imd immune deficiency 0.087
cwo clockwork orange 0.086
Cyp9b2 Cytochrome P450-9b2 0.086
p53 CG33336 gene product from transcript CG33336-RB 0.085
kibra kibra ortholog 0.083
Cyp6a9 Cytochrome P450-6a9 0.083
DNApol-eta CG7143 gene product from transcript CG7143-RA 0.083
Tre Trehalose-sensitivity 0.081
Itp-r83A Inositol 1,4,5,-tris-phosphate receptor 0.080
mus309 mutagen-sensitive 309 0.075
dsx doublesex 0.074
Hr96 Hormone receptor-like in 96 0.072
Clk Clock 0.070
Gr28b Gustatory receptor 28b 0.068
Gyc76C Guanylyl cyclase at 76C 0.068
dm diminutive 0.068
Chrac-14 CG13399 gene product from transcript CG13399-RA 0.065
ple pale 0.064
brp bruchpilot 0.063
Met Methoprene-tolerant 0.059
Nmdar1 NMDA receptor 1 0.057
SNF4Agamma SNF4/AMP-activated protein kinase gamma subunit 0.056
Nf1 Neurofibromin 1 0.056
CG14935 CG14935 gene product from transcript CG14935-RA 0.054
Cyp6d5 CG3050 gene product from transcript CG3050-RA 0.054
Ir76b Ionotropic receptor 76b 0.050
Gr43a Gustatory receptor 43a 0.050
Dh Diuretic hormone 0.049
Dsk Drosulfakinin 0.048
Mst57Db Male-specific RNA 57Db 0.047
Gr8a Gustatory receptor 8a 0.046
nAcRbeta-96A nicotinic Acetylcholine Receptor beta 96A 0.045
if inflated 0.045
CG6191 CG6191 gene product from transcript CG6191-RA 0.045
Obp49a Odorant-binding protein 49a 0.044
CG4239 CG4239 gene product from transcript CG4239-RA 0.044
oa2 octopamine receptor 2 0.044
CG6834 CG6834 gene product from transcript CG6834-RA 0.043
CG10200 CG10200 gene product from transcript CG10200-RB 0.043
mmd mind-meld 0.042
Cyp12a5 CG11821 gene product from transcript CG11821-RA 0.042
ap apterous 0.042
Fer2 48 related 2 0.042
Epac CG34392 gene product from transcript CG34392-RC 0.042
Atg9 Autophagy-specific gene 9 0.041
Caki Calcium/calmodulin-dependent protein kinase 0.041
CG9171 CG9171 gene product from transcript CG9171-RC 0.040
Smg1 CG32743 gene product from transcript CG32743-RA 0.040
CG2678 CG2678 gene product from transcript CG2678-RA 0.040
Ugt36Bc CG17932 gene product from transcript CG17932-RB 0.039
Or67d Odorant receptor 67d 0.039
Thor CG8846 gene product from transcript CG8846-RA 0.039
fd85E forkhead domain 85E 0.039
nbs CG6754 gene product from transcript CG6754-RC 0.038
mtt mangetout 0.038
mus308 mutagen-sensitive 308 0.038
Gr33a Gustatory receptor 33a 0.037
noc no ocelli 0.037
Vap-33-1 CG5014 gene product from transcript CG5014-RB 0.036
LvpD Larval visceral protein D 0.036
Gr64e Gustatory receptor 64e 0.036
Eaat2 Excitatory amino acid transporter 2 0.036
Cyp6d4 CG12800 gene product from transcript CG12800-RA 0.036
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Homo sapiens
Name Description Probability Func Analog Organism
TP53 tumor protein p53 0.997
BCL2L1 BCL2-like 1 0.994
RELA v-rel reticuloendotheliosis viral oncogene homolog A (avian) 0.974
GSTM1 glutathione S-transferase mu 1 0.915
ESR1 estrogen receptor 1 0.895
BCL2 B-cell CLL/lymphoma 2 0.844
BRCA1 breast cancer 1, early onset 0.823
GSTM2 glutathione S-transferase mu 2 (muscle) 0.756
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.646
DRD2 dopamine receptor D2 0.617
NCOR2 nuclear receptor corepressor 2 0.491
BAX BCL2-associated X protein 0.476
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.378
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.349
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.309
CAMK2A calcium/calmodulin-dependent protein kinase II alpha 0.295
XIAP X-linked inhibitor of apoptosis 0.250
MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 0.224
LAT linker for activation of T cells 0.217
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.208
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 0.192
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.187
PPP1R9B protein phosphatase 1, regulatory (inhibitor) subunit 9B 0.186
KCNA1 potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) 0.178
GSTM4 glutathione S-transferase mu 4 0.176
PLAUR plasminogen activator, urokinase receptor 0.167
CCT4 chaperonin containing TCP1, subunit 4 (delta) 0.164
PTPN1 protein tyrosine phosphatase, non-receptor type 1 0.151
DLG4 discs, large homolog 4 (Drosophila) 0.148
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.140
DNMT1 DNA (cytosine-5-)-methyltransferase 1 0.140
BLM Bloom syndrome, RecQ helicase-like 0.140
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 0.139
CRHR1 corticotropin releasing hormone receptor 1 0.139
TGFB1 transforming growth factor, beta 1 0.137
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit 0.137
WRN Werner syndrome, RecQ helicase-like 0.132
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.127
CRH corticotropin releasing hormone 0.124
MPDZ multiple PDZ domain protein 0.119
HDAC3 histone deacetylase 3 0.118
SP1 Sp1 transcription factor 0.113
TICAM2 toll-like receptor adaptor molecule 2 0.101
TCP1 t-complex 1 0.099
BAK1 BCL2-antagonist/killer 1 0.098
ADORA2A adenosine A2a receptor 0.091
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.090
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.089
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.088
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.080
NR4A1 nuclear receptor subfamily 4, group A, member 1 0.080
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.078
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) 0.078
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.071
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.069
BAD BCL2-associated agonist of cell death 0.068
ACACA acetyl-CoA carboxylase alpha 0.068
CASP7 caspase 7, apoptosis-related cysteine peptidase 0.067
ITGB1BP3 integrin beta 1 binding protein 3 0.065
PRSS2 protease, serine, 2 (trypsin 2) 0.057
HDAC1 histone deacetylase 1 0.049
HSPA1B heat shock 70kDa protein 1B 0.049
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.047
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.046
PPARA peroxisome proliferator-activated receptor alpha 0.046
MSH6 mutS homolog 6 (E. coli) 0.045
HIPK2 homeodomain interacting protein kinase 2 0.044
DUSP23 dual specificity phosphatase 23 0.044
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 0.043
SIN3A SIN3 homolog A, transcription regulator (yeast) 0.042
ACVR1B activin A receptor, type IB 0.042
VAC14 Vac14 homolog (S. cerevisiae) 0.040
AKAP1 A kinase (PRKA) anchor protein 1 0.040
MDM4 Mdm4 p53 binding protein homolog (mouse) 0.040
CDKN2A cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) 0.039
CCR5 chemokine (C-C motif) receptor 5 0.038
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.037
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) 0.035
IL1R1 interleukin 1 receptor, type I 0.035
BRCA2 breast cancer 2, early onset 0.034
HNF4A hepatocyte nuclear factor 4, alpha 0.034
ERBB4 v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) 0.034
DLGAP1 discs, large (Drosophila) homolog-associated protein 1 0.034
BCL2A1 BCL2-related protein A1 0.033
TRADD TNFRSF1A-associated via death domain 0.033
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) 0.033
GRB10 growth factor receptor-bound protein 10 0.033
ATR ataxia telangiectasia and Rad3 related 0.032
NCL nucleolin 0.031
TIMP2 TIMP metallopeptidase inhibitor 2 0.031
PTPRB protein tyrosine phosphatase, receptor type, B 0.029
KCNA4 potassium voltage-gated channel, shaker-related subfamily, member 4 0.029
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.029
CHEK2 CHK2 checkpoint homolog (S. pombe) 0.028
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 0.027
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.027
SPRR2A small proline-rich protein 2A 0.027
ICAM1 intercellular adhesion molecule 1 0.027
WT1 Wilms tumor 1 0.027
PML promyelocytic leukemia 0.026
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Mus musculus
Name Description Probability Func Analog Organism
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.999
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.998
Drd2 dopamine receptor D2 0.993
Pparg peroxisome proliferator activated receptor gamma 0.990
Trp53 transformation related protein 53 0.978
Grm1 glutamate receptor, metabotropic 1 0.949
Gnas GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus 0.922
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 0.901
Nos1 nitric oxide synthase 1, neuronal 0.868
Cav1 caveolin 1, caveolae protein 0.862
Clock circadian locomotor output cycles kaput 0.836
Pnpla2 patatin-like phospholipase domain containing 2 0.774
Bcl2l11 BCL2-like 11 (apoptosis facilitator) 0.753
Prkcc protein kinase C, gamma 0.729
Bcl2 B-cell leukemia/lymphoma 2 0.713
Ldb3 LIM domain binding 3 0.669
Arntl aryl hydrocarbon receptor nuclear translocator-like 0.644
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.632
Mef2d myocyte enhancer factor 2D 0.610
Homer1 homer homolog 1 (Drosophila) 0.570
Drd1a dopamine receptor D1A 0.502
Brca1 breast cancer 1 0.492
Stat3 signal transducer and activator of transcription 3 0.491
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 0.479
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) 0.470
Per2 period homolog 2 (Drosophila) 0.459
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 0.440
Kl klotho 0.432
Cd44 CD44 antigen 0.425
Bax BCL2-associated X protein 0.425
Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 0.420
Npy2r neuropeptide Y receptor Y2 0.403
Grb10 growth factor receptor bound protein 10 0.402
Prkaca protein kinase, cAMP dependent, catalytic, alpha 0.390
Akt1 thymoma viral proto-oncogene 1 0.390
Chrnb2 cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal) 0.361
Insr insulin receptor 0.353
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100 0.345
Igf1r insulin-like growth factor I receptor 0.341
Actn2 actinin alpha 2 0.335
Csf1 colony stimulating factor 1 (macrophage) 0.313
Camk2a calcium/calmodulin-dependent protein kinase II alpha 0.296
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 0.295
Ezh2 enhancer of zeste homolog 2 (Drosophila) 0.292
Ccl2 chemokine (C-C motif) ligand 2 0.292
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha 0.292
Pomc pro-opiomelanocortin-alpha 0.291
Gnaq guanine nucleotide binding protein, alpha q polypeptide 0.290
Dlgap1 discs, large (Drosophila) homolog-associated protein 1 0.289
Lepr leptin receptor 0.287
Mapkapk2 MAP kinase-activated protein kinase 2 0.280
Nr3c1 nuclear receptor subfamily 3, group C, member 1 0.267
Adrb1 adrenergic receptor, beta 1 0.262
Prkce protein kinase C, epsilon 0.260
Sstr4 somatostatin receptor 4 0.255
Shank2 SH3/ankyrin domain gene 2 0.250
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B 0.245
Igf2 insulin-like growth factor 2 0.241
Cebpb CCAAT/enhancer binding protein (C/EBP), beta 0.235
Tgfb1 transforming growth factor, beta 1 0.227
Mmp14 matrix metallopeptidase 14 (membrane-inserted) 0.200
Stat6 signal transducer and activator of transcription 6 0.199
Chrna6 cholinergic receptor, nicotinic, alpha polypeptide 6 0.195
Oprk1 opioid receptor, kappa 1 0.193
Pgr progesterone receptor 0.182
Irs2 insulin receptor substrate 2 0.182
Htr4 5 hydroxytryptamine (serotonin) receptor 4 0.180
Ncor2 nuclear receptor co-repressor 2 0.178
Lep leptin 0.169
Mmp9 matrix metallopeptidase 9 0.166
Mas1 MAS1 oncogene 0.165
Adora2a adenosine A2a receptor 0.155
Onecut1 one cut domain, family member 1 0.153
Crhr1 corticotropin releasing hormone receptor 1 0.150
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 0.150
Vdr vitamin D receptor 0.148
Sstr1 somatostatin receptor 1 0.147
Ltk leukocyte tyrosine kinase 0.146
Glra1 glycine receptor, alpha 1 subunit 0.145
Itgb2l integrin beta 2-like 0.143
Nkx2-2 NK2 transcription factor related, locus 2 (Drosophila) 0.142
Adra2b adrenergic receptor, alpha 2b 0.141
Npy1r neuropeptide Y receptor Y1 0.140
Adra1a adrenergic receptor, alpha 1a 0.140
Mc3r melanocortin 3 receptor 0.137
Shc3 src homology 2 domain-containing transforming protein C3 0.136
Lyz2 lysozyme 2 0.135
Sirt1 sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae) 0.134
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 0.132
Mef2c myocyte enhancer factor 2C 0.130
Junb Jun-B oncogene 0.127
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.123
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D 0.121
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A 0.119
Vhl von Hippel-Lindau tumor suppressor 0.118
Dlg2 discs, large homolog 2 (Drosophila) 0.115
Plcg1 phospholipase C, gamma 1 0.114
Ifng interferon gamma 0.113
Cyp8b1 cytochrome P450, family 8, subfamily b, polypeptide 1 0.111
Plcb1 phospholipase C, beta 1 0.111
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Saccharomyces cerevisiae
Name Description Probability Func Analog Organism