IMP
Process View
The network for 'regulation of smooth muscle cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
regulation of smooth muscle cell proliferation
Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| Flt1 | FMS-related tyrosine kinase 1 | 0.452 | |
| Fos | FBJ osteosarcoma oncogene | 0.417 | |
| Tnfrsf1a | tumor necrosis factor receptor superfamily, member 1a | 0.322 | |
| Kitlg | KIT ligand | 0.265 | |
| Slc8a3 | solute carrier family 8 (sodium/calcium exchanger), member 3 | 0.224 | |
| Smad7 | SMAD family member 7 | 0.170 | |
| Grb2 | growth factor receptor bound protein 2 | 0.166 | |
| Ptp4a1 | protein tyrosine phosphatase type IVA, member 1 | 0.147 | |
| Tgfbr3 | transforming growth factor, beta receptor III | 0.144 | |
| Tgfbr2 | transforming growth factor, beta receptor II | 0.143 | |
| Adrb1 | adrenergic, beta-1-, receptor | 0.138 | |
| Icam2 | intercellular adhesion molecule 2 | 0.135 | |
| Sirpa | signal-regulatory protein alpha | 0.128 | |
| Ndst1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 | 0.125 | |
| Slc6a7 | solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 | 0.118 | |
| Slco2b1 | solute carrier organic anion transporter family, member 2b1 | 0.117 | |
| Kcnj8 | potassium inwardly-rectifying channel, subfamily J, member 8 | 0.114 | |
| Btg2 | BTG family, member 2 | 0.106 | |
| Phkg1 | phosphorylase kinase, gamma 1 | 0.103 | |
| Ucn | urocortin | 0.102 | |
| Mrgprf | MAS-related GPR, member F | 0.102 | |
| Cav1 | caveolin 1, caveolae protein | 0.100 | |
| Ednrb | endothelin receptor type B | 0.100 | |
| Ncr1 | natural cytotoxicity triggering receptor 1 | 0.099 | |
| LOC100360403 | ATP-binding cassette, sub-family C, member 9-like | 0.096 | |
| Prlhr | prolactin releasing hormone receptor | 0.095 | |
| Prkcd | protein kinase C, delta | 0.093 | |
| Itpr2 | inositol 1,4,5-triphosphate receptor, type 2 | 0.090 | |
| Synpo | synaptopodin | 0.089 | |
| Gpr116 | G protein-coupled receptor 116 | 0.089 | |
| Pla2g4a | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 0.088 | |
| Snrk | SNF related kinase | 0.087 | |
| Stat3 | signal transducer and activator of transcription 3 | 0.087 | |
| Clic4 | chloride intracellular channel 4 | 0.087 | |
| Il9r | interleukin 9 receptor | 0.086 | |
| Ednra | endothelin receptor type A | 0.086 | |
| Gnb2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.085 | |
| Trhr2 | thyrotropin releasing hormone receptor 2 | 0.085 | |
| Dlg3 | discs, large homolog 3 (Drosophila) | 0.084 | |
| Gabrg1 | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 0.082 | |
| Rara | retinoic acid receptor, alpha | 0.081 | |
| Atf3 | activating transcription factor 3 | 0.081 | |
| Ctsj | cathepsin J | 0.077 | |
| Dag1 | dystroglycan 1 (dystrophin-associated glycoprotein 1) | 0.077 | |
| Irs1 | insulin receptor substrate 1 | 0.076 | |
| Cd4 | Cd4 molecule | 0.076 | |
| Batf3 | basic leucine zipper transcription factor, ATF-like 3 | 0.075 | |
| Slc7a12 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 | 0.073 | |
| Gper | G protein-coupled estrogen receptor 1 | 0.073 | |
| Ldlr | low density lipoprotein receptor | 0.071 | |
| Prkcg | protein kinase C, gamma | 0.071 | |
| Gna12 | guanine nucleotide binding protein (G protein) alpha 12 | 0.071 | |
| Gpnmb | glycoprotein (transmembrane) nmb | 0.071 | |
| Cdc42bpb | CDC42 binding protein kinase beta (DMPK-like) | 0.070 | |
| Myh9 | myosin, heavy chain 9, non-muscle | 0.069 | |
| Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1 | 0.069 | |
| Akt2 | v-akt murine thymoma viral oncogene homolog 2 | 0.068 | |
| Notch3 | Notch homolog 3 (Drosophila) | 0.068 | |
| Sdc3 | syndecan 3 | 0.068 | |
| Timp3 | TIMP metallopeptidase inhibitor 3 | 0.066 | |
| Vipr2 | vasoactive intestinal peptide receptor 2 | 0.066 | |
| Galr3 | galanin receptor 3 | 0.066 | |
| Sbno2 | strawberry notch homolog 2 (Drosophila) | 0.066 | |
| Mcl1 | myeloid cell leukemia sequence 1 | 0.066 | |
| Slco2a1 | solute carrier organic anion transporter family, member 2a1 | 0.065 | |
| Adora2a | adenosine A2a receptor | 0.065 | |
| F13a1 | coagulation factor XIII, A1 polypeptide | 0.064 | |
| Ftl | ferritin, light polypeptide | 0.064 | |
| Gja1 | gap junction protein, alpha 1 | 0.064 | |
| Dmd | dystrophin | 0.063 | |
| Naaladl1 | N-acetylated alpha-linked acidic dipeptidase-like 1 | 0.063 | |
| Calcrl | calcitonin receptor-like | 0.061 | |
| Csnk1g2 | casein kinase 1, gamma 2 | 0.061 | |
| Arhgap1 | Rho GTPase activating protein 1 | 0.061 | |
| Bmp6 | bone morphogenetic protein 6 | 0.060 | |
| MGC112715 | hypothetical protein LOC690899 | 0.059 | |
| Cd38 | CD38 molecule | 0.059 | |
| Teddm1 | transmembrane epididymal protein 1 | 0.059 | |
| Cav2 | caveolin 2 | 0.059 | |
| Crk | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.059 | |
| Slc22a6 | solute carrier family 22 (organic anion transporter), member 6 | 0.059 | |
| Mapk8ip1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.058 | |
| Smad1 | SMAD family member 1 | 0.058 | |
| Chrm1 | cholinergic receptor, muscarinic 1 | 0.058 | |
| Faslg | Fas ligand (TNF superfamily, member 6) | 0.058 | |
| Rgs4 | regulator of G-protein signaling 4 | 0.057 | |
| Unc5b | unc-5 homolog B (C. elegans) | 0.057 | |
| Cpxm2 | carboxypeptidase X (M14 family), member 2 | 0.057 | |
| Slc7a9 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 0.057 | |
| Ltbr | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.057 | |
| Cd14 | CD14 molecule | 0.057 | |
| Pth2r | parathyroid hormone 2 receptor | 0.056 | |
| Nkx2-5 | NK2 transcription factor related, locus 5 (Drosophila) | 0.056 | |
| Socs3 | suppressor of cytokine signaling 3 | 0.055 | |
| Rhox5 | reproductive homeobox 5 | 0.053 | |
| Strn | striatin, calmodulin binding protein | 0.053 | |
| Grk1 | G protein-coupled receptor kinase 1 | 0.053 | |
| Mas1 | MAS1 oncogene | 0.053 | |
| Dmbt1 | deleted in malignant brain tumors 1 | 0.053 | |
| Dhrs9 | dehydrogenase/reductase (SDR family) member 9 | 0.052 |
Loading network...
Homo sapiens
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 1.000 | |
| FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.999 | |
| EGFR | epidermal growth factor receptor | 0.999 | |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.998 | |
| VEGFA | vascular endothelial growth factor A | 0.996 | |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.996 | |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.995 | |
| IL6 | interleukin 6 (interferon, beta 2) | 0.994 | |
| CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.991 | |
| ESR1 | estrogen receptor 1 | 0.990 | |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.986 | |
| IL8 | interleukin 8 | 0.968 | |
| CCR5 | chemokine (C-C motif) receptor 5 | 0.939 | |
| PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.921 | |
| JAG1 | jagged 1 | 0.910 | |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.892 | |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.889 | |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.881 | |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.848 | |
| JUP | junction plakoglobin | 0.772 | |
| EP300 | E1A binding protein p300 | 0.768 | |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.763 | |
| HNF4A | hepatocyte nuclear factor 4, alpha | 0.757 | |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.754 | |
| NRP1 | neuropilin 1 | 0.751 | |
| C1QA | complement component 1, q subcomponent, A chain | 0.746 | |
| CCL4 | chemokine (C-C motif) ligand 4 | 0.735 | |
| FN1 | fibronectin 1 | 0.725 | |
| NOSTRIN | nitric oxide synthase trafficker | 0.690 | |
| NCOR2 | nuclear receptor corepressor 2 | 0.689 | |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.684 | |
| BMPR1A | bone morphogenetic protein receptor, type IA | 0.665 | |
| TBXA2R | thromboxane A2 receptor | 0.658 | |
| FGFR1 | fibroblast growth factor receptor 1 | 0.645 | |
| IL1B | interleukin 1, beta | 0.561 | |
| CREBBP | CREB binding protein | 0.552 | |
| EPAS1 | endothelial PAS domain protein 1 | 0.530 | |
| ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.520 | |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | 0.516 | |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.495 | |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.482 | |
| NOTCH1 | notch 1 | 0.482 | |
| PGF | placental growth factor | 0.438 | |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.436 | |
| STAT5A | signal transducer and activator of transcription 5A | 0.396 | |
| DSG2 | desmoglein 2 | 0.379 | |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.375 | |
| SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.371 | |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.358 | |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.356 | |
| TGFB1 | transforming growth factor, beta 1 | 0.355 | |
| IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.349 | |
| ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.343 | |
| CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.331 | |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.327 | |
| AR | androgen receptor | 0.319 | |
| CCR7 | chemokine (C-C motif) receptor 7 | 0.310 | |
| TGFB3 | transforming growth factor, beta 3 | 0.308 | |
| FGF10 | fibroblast growth factor 10 | 0.298 | |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.297 | |
| IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.295 | |
| INSR | insulin receptor | 0.294 | |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.279 | |
| PXN | paxillin | 0.277 | |
| IL2RB | interleukin 2 receptor, beta | 0.271 | |
| CD34 | CD34 molecule | 0.245 | |
| C1QB | complement component 1, q subcomponent, B chain | 0.245 | |
| IL23A | interleukin 23, alpha subunit p19 | 0.240 | |
| RUNX1 | runt-related transcription factor 1 | 0.236 | |
| FSTL1 | follistatin-like 1 | 0.232 | |
| BCAR1 | breast cancer anti-estrogen resistance 1 | 0.217 | |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.211 | |
| RNASE4 | ribonuclease, RNase A family, 4 | 0.204 | |
| NCOA1 | nuclear receptor coactivator 1 | 0.203 | |
| FBLN1 | fibulin 1 | 0.202 | |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.202 | |
| PGR | progesterone receptor | 0.202 | |
| FGF7 | fibroblast growth factor 7 | 0.199 | |
| ENG | endoglin | 0.198 | |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.194 | |
| SKP1 | S-phase kinase-associated protein 1 | 0.192 | |
| PPP5C | protein phosphatase 5, catalytic subunit | 0.187 | |
| S100B | S100 calcium binding protein B | 0.186 | |
| CRYAB | crystallin, alpha B | 0.176 | |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.174 | |
| IFNG | interferon, gamma | 0.173 | |
| CCL5 | chemokine (C-C motif) ligand 5 | 0.172 | |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.171 | |
| CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.166 | |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.164 | |
| SIRT1 | sirtuin 1 | 0.163 | |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.158 | |
| MPO | myeloperoxidase | 0.157 | |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.156 | |
| PELI3 | pellino homolog 3 (Drosophila) | 0.153 | |
| DPP4 | dipeptidyl-peptidase 4 | 0.151 | |
| PRMT2 | protein arginine methyltransferase 2 | 0.148 | |
| KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.148 | |
| IRS1 | insulin receptor substrate 1 | 0.147 | |
| CCL8 | chemokine (C-C motif) ligand 8 | 0.146 |