The network for 'purine nucleoside catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

purine nucleoside catabolic process

The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).

Rattus norvegicus
Name Description Probability Func Analog Organism
Rhoa ras homolog gene family, member A 0.860
Tagln transgelin 0.703
Arl1 ADP-ribosylation factor-like 1 0.569
Gria2 glutamate receptor, ionotropic, AMPA 2 0.534
Sumo1 SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) 0.527
Psmc1 proteasome (prosome, macropain) 26S subunit, ATPase, 1 0.434
Psmc5 proteasome (prosome, macropain) 26S subunit, ATPase, 5 0.417
Anxa2 annexin A2 0.397
Lman1 lectin, mannose-binding, 1 0.373
Acta2 smooth muscle alpha-actin 0.367
Gdi2 GDP dissociation inhibitor 2 0.320
Myl9 myosin, light chain 9, regulatory 0.319
Amph amphiphysin 0.316
Pls3 plastin 3 (T-isoform) 0.308
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 0.288
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 0.286
Gipc1 GIPC PDZ domain containing family, member 1 0.274
Cdc42 cell division cycle 42 (GTP binding protein) 0.254
Jtb jumping translocation breakpoint 0.239
Cyth3 cytohesin 3 0.235
Actg2 actin, gamma 2, smooth muscle, enteric 0.227
Cap1 CAP, adenylate cyclase-associated protein 1 (yeast) 0.225
Anxa5 annexin A5 0.216
Arpc1b actin related protein 2/3 complex, subunit 1B 0.212
Pja2 praja 2, RING-H2 motif containing 0.207
Pfn1 profilin 1 0.206
Gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 0.197
Psma7 proteasome (prosome, macropain) subunit, alpha type 7 0.196
Psmd4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 0.195
Prkch protein kinase C, eta 0.183
Ywhaq tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide 0.182
Rap1b RAP1B, member of RAS oncogene family 0.180
Rab5a RAB5A, member RAS oncogene family 0.179
Tpm4 tropomyosin 4 0.178
Dlg3 discs, large homolog 3 (Drosophila) 0.171
Fgfr1 Fibroblast growth factor receptor 1 0.171
Psma5 proteasome (prosome, macropain) subunit, alpha type 5 0.169
S100a10 S100 calcium binding protein A10 0.166
Hnrnpf heterogeneous nuclear ribonucleoprotein F 0.163
Pdcl phosducin-like 0.158
Limd2 LIM domain containing 2 0.154
Cmklr1 chemokine-like receptor 1 0.153
Mapk3 mitogen activated protein kinase 3 0.149
Myadm myeloid-associated differentiation marker 0.149
Akirin2 akirin 2 0.149
Adprh ADP-ribosylarginine hydrolase 0.145
Copb2 coatomer protein complex, subunit beta 2 (beta prime) 0.145
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 0.142
Tagln2 transgelin 2 0.140
Apoa1 apolipoprotein A-I 0.140
Exoc5 exocyst complex component 5 0.140
Rhoc ras homolog gene family, member C 0.139
Utrn utrophin 0.135
S100a6 S100 calcium binding protein A6 0.131
Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) 0.131
Myh7 myosin, heavy chain 7, cardiac muscle, beta 0.128
Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) 0.128
Cnn1 calponin 1, basic, smooth muscle 0.128
Syn1 synapsin I 0.127
Mybpc2 myosin binding protein C, fast-type 0.126
Cast calpastatin 0.126
Vim vimentin 0.124
Pak1 p21 protein (Cdc42/Rac)-activated kinase 1 0.124
Kcnq3 potassium voltage-gated channel, KQT-like subfamily, member 3 0.122
Wipf3 WAS/WASL interacting protein family, member 3 0.121
Cngb1 cyclic nucleotide gated channel beta 1 0.120
Scn3b sodium channel, voltage-gated, type III, beta 0.117
Psmd2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 0.117
Dag1 dystroglycan 1 (dystrophin-associated glycoprotein 1) 0.116
Nptn neuroplastin 0.115
Scarb1 scavenger receptor class B, member 1 0.115
Actc1 actin, alpha, cardiac muscle 1 0.114
Shank2 SH3 and multiple ankyrin repeat domains 2 0.111
Slc9a3r2 solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2 0.110
Hspb1 heat shock protein 1 0.110
Mapre1 microtubule-associated protein, RP/EB family, member 1 0.108
Psmc3 proteasome (prosome, macropain) 26S subunit, ATPase 3 0.108
Kcnab2 potassium voltage-gated channel, shaker-related subfamily, beta member 2 0.108
Dnaja2 DnaJ (Hsp40) homolog, subfamily A, member 2 0.108
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 0.107
Ddr1 discoidin domain receptor tyrosine kinase 1 0.106
Rab8b RAB8B, member RAS oncogene family 0.104
RT1-DMa RT1 class II, locus DMa 0.103
Epas1 endothelial PAS domain protein 1 0.103
Sh3gl2 SH3-domain GRB2-like 2 0.102
Actn2 actinin alpha 2 0.101
Lynx1 Ly6/neurotoxin 1 0.100
Racgap1 Rac GTPase-activating protein 1 0.099
Dnaja4 DnaJ (Hsp40) homolog, subfamily A, member 4 0.099
Snca synuclein, alpha (non A4 component of amyloid precursor) 0.099
Myh6 myosin, heavy chain 6, cardiac muscle, alpha 0.098
Atp5b ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.097
Tap1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.097
Eif4a2 eukaryotic translation initiation factor 4A, isoform 2 0.097
Dlg1 discs, large homolog 1 (Drosophila) 0.097
Chrm1 cholinergic receptor, muscarinic 1 0.097
Snap25 synaptosomal-associated protein 25 0.096
Nckap1 NCK-associated protein 1 0.095
Myh11 myosin, heavy chain 11, smooth muscle 0.095
Eif5 eukaryotic translation initiation factor 5 0.095
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Caenorhabditis elegans
Name Description Probability Func Analog Organism
gpr-1 Protein GPR-1 0.595
hsp-16.1 Protein HSP-16.1 0.483
F44E5.4 Protein F44E5.4 0.466
D1081.8 Protein D1081.8 0.464
F10C2.4 Protein F10C2.4 0.446
goa-1 Protein GOA-1 0.366
abts-1 Protein ABTS-1 0.308
cyk-4 Protein CYK-4 0.304
nmy-2 Protein NMY-2 0.291
gei-4 Protein GEI-4 0.281
hsp-16.48 Protein HSP-16.48 0.275
lin-5 Protein LIN-5 0.260
ret-1 Protein RET-1 0.260
dpf-3 Protein DPF-3 0.256
pbs-5 Protein PBS-5 0.239
cyc-1 Protein CYC-1 0.238
frm-7 Protein FRM-7 0.236
unc-45 Protein UNC-45 0.226
miro-1 Protein MIRO-1 0.222
unc-53 Protein UNC-53 0.221
pkg-1 Protein PKG-1 0.208
zoo-1 Protein ZOO-1 0.208
gei-18 Protein GEI-18 0.200
rpt-4 Protein RPT-4 0.198
T23F11.1 Protein T23F11.1 0.197
gei-17 Protein GEI-17 0.186
alx-1 Protein ALX-1 0.179
aspm-1 Protein ASPM-1 0.175
kcc-1 Protein KCC-1 0.171
sas-4 Protein SAS-4 0.162
etr-1 Protein ETR-1 0.156
hsp-1 Protein HSP-1 0.155
csr-1 Protein CSR-1 0.154
gpr-2 Protein GPR-2 0.152
spd-2 Protein SPD-2 0.152
crt-1 Protein CRT-1 0.150
snf-1 Protein SNF-1 0.148
lfi-1 Protein LFI-1 0.147
mai-2 Protein MAI-2 0.146
chc-1 Protein CHC-1 0.142
rab-5 Protein RAB-5 0.141
aph-2 Protein APH-2 0.137
tag-341 Protein TAG-341 0.137
F33E11.3 Protein F33E11.3 0.135
F52G3.1 Protein F52G3.1 0.135
sem-5 Protein SEM-5 0.133
rsr-2 Protein RSR-2 0.129
rfp-1 Protein RFP-1 0.128
atp-2 Protein ATP-2 0.128
sec-24.1 Protein SEC-24.1 0.127
CELE_Y69A2AR.16 Protein Y69A2AR.16 0.126
F53F10.2 Protein F53F10.2 0.125
lin-10 Protein LIN-10 0.124
unc-54 Protein UNC-54 0.123
C30F12.4 Protein C30F12.4 0.120
F44E5.1 Protein F44E5.1 0.117
div-1 Protein DIV-1 0.116
glo-4 Protein GLO-4 0.115
pxf-1 Protein PXF-1 0.115
unc-40 Protein UNC-40 0.114
hsp-16.2 Protein HSP-16.2 0.112
usp-14 Protein USP-14 0.112
drh-3 Protein DRH-3 0.109
asp-3 Protein ASP-3 0.107
coh-3 Protein COH-3 0.106
ykt-6 Protein YKT-6 0.105
mcm-6 Protein MCM-6 0.104
C42C1.8 Protein C42C1.8 0.104
let-60 Protein LET-60 0.103
knl-1 Protein KNL-1 0.102
B0495.2 Protein B0495.2 0.101
CELE_W03F9.10 Protein W03F9.10 0.101
bet-2 Protein BET-2 0.100
CELE_Y60A3A.9 Protein Y60A3A.9 0.099
mig-2 Protein MIG-2 0.098
Y32B12B.4 Protein Y32B12B.4 0.098
cyn-4 Protein CYN-4 0.098
apg-1 Protein APG-1 0.097
cmd-1 Protein CMD-1 0.097
ced-10 Protein CED-10 0.096
CELE_Y48A5A.1 Protein Y48A5A.1 0.096
gpd-4 Protein GPD-4 0.095
C10G11.7 Protein C10G11.7 0.095
bmk-1 Protein BMK-1 0.095
ncs-2 Protein NCS-2 0.094
CELE_Y43F8C.7 Protein Y43F8C.7 0.092
daf-19 Protein DAF-19 0.092
plc-3 Protein PLC-3 0.092
ife-2 Protein IFE-2 0.092
unc-26 Protein UNC-26 0.092
vab-10 Protein VAB-10 0.091
ercc-1 Protein ERCC-1 0.091
glh-4 Protein GLH-4 0.091
let-502 Protein LET-502 0.091
R53.4 Protein R53.4 0.089
csnk-1 Protein CSNK-1 0.088
nlg-1 Protein NLG-1 0.088
D1043.1 Protein D1043.1 0.088
unc-71 Protein UNC-71 0.088
fncm-1 Protein FNCM-1 0.087
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Danio rerio
Name Description Probability Func Analog Organism
dag1 dystroglycan 1 0.017
copeb core promoter element binding protein 0.012
cacnb1 calcium channel, voltage-dependent, beta 1 subunit 0.012
alcamb activated leukocyte cell adhesion molecule b 0.011
Loading network...
Drosophila melanogaster
Name Description Probability Func Analog Organism
Pi3K92E CG4141 gene product from transcript CG4141-RB 0.962
Khc Kinesin heavy chain 0.763
Rac1 CG2248 gene product from transcript CG2248-RA 0.684
Chc Clathrin heavy chain 0.644
Wnk CG7177 gene product from transcript CG7177-RA 0.621
Pten CG5671 gene product from transcript CG5671-RB 0.575
mbc myoblast city 0.562
ttk tramtrack 0.536
Eph Eph receptor tyrosine kinase 0.495
arm armadillo 0.475
drk downstream of receptor kinase 0.434
Moe Moesin 0.425
chic chickadee 0.422
drpr draper 0.402
usp ultraspiracle 0.400
Rheb CG1081 gene product from transcript CG1081-RA 0.396
stai stathmin 0.391
Arf79F ADP ribosylation factor 79F 0.385
Ras64B Ras oncogene at 64B 0.372
bs blistered 0.368
aux auxillin 0.363
EndoGI Endonuclease G inhibitor 0.362
Myo31DF Myosin 31DF 0.362
CG8155 CG8155 gene product from transcript CG8155-RA 0.354
Pk61C Protein kinase 61C 0.343
trp transient receptor potential 0.341
Caps Calcium activated protein for secretion 0.321
mus210 mutagen-sensitive 210 0.313
Mer Merlin 0.311
WASp CG1520 gene product from transcript CG1520-RA 0.310
RhoGAP68F CG6811 gene product from transcript CG6811-RA 0.310
Eip63E Ecdysone-induced protein 63E 0.308
TER94 CG2331 gene product from transcript CG2331-RA 0.308
XNP CG4548 gene product from transcript CG4548-RA 0.308
dos daughter of sevenless 0.307
Ras85D Ras oncogene at 85D 0.306
Vps35 Vacuolar protein sorting 35 0.301
dys dysfusion 0.291
Rab5 Rab-protein 5 0.289
Ced-12 CG5336 gene product from transcript CG5336-RA 0.288
cenG1A centaurin gamma 1A 0.287
RhoGAPp190 CG32555 gene product from transcript CG32555-RB 0.283
CG7139 CG7139 gene product from transcript CG7139-RB 0.281
mbt mushroom bodies tiny 0.279
Apc APC-like 0.278
Shc SHC-adaptor protein 0.274
Tl Toll 0.271
Uba1 Ubiquitin activating enzyme 1 0.269
ptc patched 0.266
RpL15 Ribosomal protein L15 0.262
pod1 CG4532 gene product from transcript CG4532-RF 0.260
puc puckered 0.257
trio CG18214 gene product from transcript CG18214-RA 0.257
cno canoe 0.255
MTF-1 Metal response element-binding Transcription Factor-1 0.253
CalpB Calpain-B 0.252
baz bazooka 0.248
CycA Cyclin A 0.241
Rpd3 CG7471 gene product from transcript CG7471-RA 0.239
mus205 mutagen-sensitive 205 0.237
Ephrin CG1862 gene product from transcript CG1862-RA 0.237
tkv thickveins 0.236
Pak3 CG14895 gene product from transcript CG14895-RA 0.236
stumps CG31317 gene product from transcript CG31317-RC 0.236
CG3573 CG3573 gene product from transcript CG3573-RA 0.235
rictor rapamycin-insensitive companion of Tor 0.232
sun stunted 0.232
Gyc-89Db Guanylyl cyclase at 89Db 0.231
gl glass 0.220
shi shibire 0.219
neuroligin CG13772 gene product from transcript CG13772-RA 0.216
endos endosulfine 0.214
Sec61alpha CG9539 gene product from transcript CG9539-RA 0.214
Dhc64C Dynein heavy chain 64C 0.210
wupA wings up A 0.208
wal walrus 0.197
Rtnl1 CG33113 gene product from transcript CG33113-RF 0.192
sqh spaghetti squash 0.191
shrb shrub 0.189
synj synaptojanin 0.187
p130CAS CG1212 gene product from transcript CG1212-RA 0.186
CG4853 CG4853 gene product from transcript CG4853-RA 0.184
Rbsn-5 Rabenosyn-5 0.183
ben bendless 0.182
jar jaguar 0.181
CG7028 CG7028 gene product from transcript CG7028-RA 0.179
Gie novel GTPase indispensable for equal segregation of chromosomes 0.179
ATPsyn-gamma ATP synthase-gamma chain 0.176
LIMK1 LIM-kinase1 0.174
CG8334 CG8334 gene product from transcript CG8334-RA 0.174
RanBPM Ran-binding protein M 0.172
Abi Abelson interacting protein 0.169
Gyc-89Da Guanylyl cyclase at 89Da 0.169
jumu jumeau 0.168
Cip4 CG15015 gene product from transcript CG15015-RA 0.167
flw flapwing 0.166
Tm1 Tropomyosin 1 0.166
CG1021 CG1021 gene product from transcript CG1021-RE 0.163
Sbf SET domain binding factor 0.163
plexB plexin B 0.162
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Homo sapiens
Name Description Probability Func Analog Organism
CDC42 cell division cycle 42 (GTP binding protein, 25kDa) 1.000
SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) 1.000
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.000
SH3KBP1 SH3-domain kinase binding protein 1 1.000
RAB5A RAB5A, member RAS oncogene family 0.999
GRB2 growth factor receptor-bound protein 2 0.999
ARRB1 arrestin, beta 1 0.999
PTK2 PTK2 protein tyrosine kinase 2 0.998
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha 0.991
BCAR1 breast cancer anti-estrogen resistance 1 0.987
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.984
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.978
MSH2 mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) 0.975
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 0.974
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.971
FGFR2 fibroblast growth factor receptor 2 0.971
ITSN1 intersectin 1 (SH3 domain protein) 0.971
CRK v-crk sarcoma virus CT10 oncogene homolog (avian) 0.967
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 0.965
MOBKL1B MOB1, Mps One Binder kinase activator-like 1B (yeast) 0.963
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 0.962
BLM Bloom syndrome, RecQ helicase-like 0.959
THOC4 THO complex 4 0.959
DNM1 dynamin 1 0.956
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.955
CDK7 cyclin-dependent kinase 7 0.955
RABAC1 Rab acceptor 1 (prenylated) 0.954
RAD51 RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) 0.953
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.952
SFN stratifin 0.948
FLNA filamin A, alpha 0.947
DNM2 dynamin 2 0.940
ERBB2 v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) 0.933
GSK3B glycogen synthase kinase 3 beta 0.933
SOS1 son of sevenless homolog 1 (Drosophila) 0.931
NCK2 NCK adaptor protein 2 0.928
HSPA1B heat shock 70kDa protein 1B 0.927
BCL2L1 BCL2-like 1 0.924
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.924
RAB1A RAB1A, member RAS oncogene family 0.923
GRB7 growth factor receptor-bound protein 7 0.922
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11 0.914
RHOA ras homolog gene family, member A 0.910
SH3BP2 SH3-domain binding protein 2 0.910
DOCK1 dedicator of cytokinesis 1 0.906
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide 0.906
RIN3 Ras and Rab interactor 3 0.905
S100A8 S100 calcium binding protein A8 0.905
RAF1 v-raf-1 murine leukemia viral oncogene homolog 1 0.901
TNNC1 troponin C type 1 (slow) 0.900
MYO9B myosin IXB 0.895
NCK1 NCK adaptor protein 1 0.893
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.892
GDI2 GDP dissociation inhibitor 2 0.889
IQGAP1 IQ motif containing GTPase activating protein 1 0.886
MDM2 Mdm2 p53 binding protein homolog (mouse) 0.880
NCAPG non-SMC condensin I complex, subunit G 0.880
RALB v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein) 0.880
SNX9 sorting nexin 9 0.880
HSPH1 heat shock 105kDa/110kDa protein 1 0.876
CBL Cas-Br-M (murine) ecotropic retroviral transforming sequence 0.872
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.872
RAD51L3 RAD51-like 3 (S. cerevisiae) 0.870
ILK integrin-linked kinase 0.864
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.852
EEA1 early endosome antigen 1 0.852
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) 0.851
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) 0.850
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.840
CCNH cyclin H 0.837
HSPA8 heat shock 70kDa protein 8 0.833
CFL1 cofilin 1 (non-muscle) 0.831
ZMYND11 zinc finger, MYND-type containing 11 0.828
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 0.827
CORO1C coronin, actin binding protein, 1C 0.817
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.810
ABI1 abl-interactor 1 0.805
MKI67 antigen identified by monoclonal antibody Ki-67 0.800
LAMTOR2 late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 0.795
WAS Wiskott-Aldrich syndrome (eczema-thrombocytopenia) 0.794
BAIAP2 BAI1-associated protein 2 0.793
BRCA2 breast cancer 2, early onset 0.790
FOS FBJ murine osteosarcoma viral oncogene homolog 0.790
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 0.788
NCF2 neutrophil cytosolic factor 2 0.786
PFN1 profilin 1 0.780
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.773
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B 0.769
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.764
RGS2 regulator of G-protein signaling 2, 24kDa 0.760
ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 0.760
EGFR epidermal growth factor receptor 0.752
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 0.749
TOR1A torsin family 1, member A (torsin A) 0.746
CBLB Cas-Br-M (murine) ecotropic retroviral transforming sequence b 0.741
ADAM15 ADAM metallopeptidase domain 15 0.739
CCR5 chemokine (C-C motif) receptor 5 0.737
OCRL oculocerebrorenal syndrome of Lowe 0.731
RAB2A RAB2A, member RAS oncogene family 0.726
SEPT2 septin 2 0.723
Loading network...
Mus musculus
Name Description Probability Func Analog Organism
Itsn1 intersectin 1 (SH3 domain protein 1A) 0.965
Dnm1 dynamin 1 0.957
Kl klotho 0.950
Lrrk2 leucine-rich repeat kinase 2 0.931
Ephb2 Eph receptor B2 0.927
Efnb2 ephrin B2 0.925
Grb2 growth factor receptor bound protein 2 0.907
Bcl2 B-cell leukemia/lymphoma 2 0.903
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.899
Epha4 Eph receptor A4 0.897
Igtp interferon gamma induced GTPase 0.894
Braf Braf transforming gene 0.874
Ret ret proto-oncogene 0.860
Trim28 tripartite motif-containing 28 0.841
Rac1 RAS-related C3 botulinum substrate 1 0.824
Arhgef7 Rho guanine nucleotide exchange factor (GEF7) 0.817
Plxna1 plexin A1 0.779
Arrb2 arrestin, beta 2 0.770
Atp5b ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit 0.765
Nf1 neurofibromatosis 1 0.764
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 0.728
Tnnt3 troponin T3, skeletal, fast 0.685
Mcm2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae) 0.674
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D 0.670
L1cam L1 cell adhesion molecule 0.622
Ppp1r9b protein phosphatase 1, regulatory subunit 9B 0.609
Spry4 sprouty homolog 4 (Drosophila) 0.606
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A 0.602
Ntf3 neurotrophin 3 0.600
Sox10 SRY-box containing gene 10 0.597
Srsf9 serine/arginine-rich splicing factor 9 0.591
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 0.586
Hif1a hypoxia inducible factor 1, alpha subunit 0.569
Des desmin 0.565
Nsf N-ethylmaleimide sensitive fusion protein 0.562
Ilk integrin linked kinase 0.558
Dync1h1 dynein cytoplasmic 1 heavy chain 1 0.546
Cbl Casitas B-lineage lymphoma 0.543
Ndel1 nuclear distribution gene E-like homolog 1 (A. nidulans) 0.541
Scn5a sodium channel, voltage-gated, type V, alpha 0.539
Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 0.527
Wdr1 WD repeat domain 1 0.524
Eea1 early endosome antigen 1 0.518
Kras v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog 0.518
Mcm7 minichromosome maintenance deficient 7 (S. cerevisiae) 0.516
Pxn paxillin 0.507
Iigp1 interferon inducible GTPase 1 0.505
Eps15 epidermal growth factor receptor pathway substrate 15 0.497
Akt1 thymoma viral proto-oncogene 1 0.496
Kalrn kalirin, RhoGEF kinase 0.491
Brca2 breast cancer 2 0.488
Asap1 ArfGAP with SH# domain, ankyrin repeat and PH domain1 0.483
Lig1 ligase I, DNA, ATP-dependent 0.482
Vars valyl-tRNA synthetase 0.475
Myo18a myosin XVIIIA 0.474
Epb4.1l2 erythrocyte protein band 4.1-like 2 0.461
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow 0.457
Mybph myosin binding protein H 0.456
Vapa vesicle-associated membrane protein, associated protein A 0.447
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 0.447
Lsm2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.446
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform 0.443
Nphs2 nephrosis 2 homolog, podocin (human) 0.441
Lyst lysosomal trafficking regulator 0.440
Ctnnb1 catenin (cadherin associated protein), beta 1 0.436
Col4a3 collagen, type IV, alpha 3 0.436
Tnni2 troponin I, skeletal, fast 2 0.429
Ap2a2 adaptor protein complex AP-2, alpha 2 subunit 0.423
Spnb2 spectrin beta 2 0.421
Epha1 Eph receptor A1 0.413
Parva parvin, alpha 0.408
Tnks1bp1 tankyrase 1 binding protein 1 0.398
Kif5b kinesin family member 5B 0.395
Spna2 spectrin alpha 2 0.395
Brca1 breast cancer 1 0.387
Vasp vasodilator-stimulated phosphoprotein 0.385
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 0.385
Mbd3 methyl-CpG binding domain protein 3 0.385
Cplx1 complexin 1 0.382
Rasa1 RAS p21 protein activator 1 0.382
Apc adenomatosis polyposis coli 0.381
Plcg1 phospholipase C, gamma 1 0.376
Vdr vitamin D receptor 0.372
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) 0.372
Adam17 a disintegrin and metallopeptidase domain 17 0.372
Pik3ca phosphatidylinositol 3-kinase, catalytic, alpha polypeptide 0.369
Ywhah tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide 0.363
Itgb1 integrin beta 1 (fibronectin receptor beta) 0.361
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit 0.360
Cd2ap CD2-associated protein 0.359
Ksr1 kinase suppressor of ras 1 0.357
Dlg4 discs, large homolog 4 (Drosophila) 0.353
Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 0.351
Rab1 RAB1, member RAS oncogene family 0.348
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide 0.347
Hrc histidine rich calcium binding protein 0.344
Clstn1 calsyntenin 1 0.344
Stxbp3a syntaxin binding protein 3A 0.343
Ppp1cb protein phosphatase 1, catalytic subunit, beta isoform 0.342
Map3k14 mitogen-activated protein kinase kinase kinase 14 0.340
Loading network...
Saccharomyces cerevisiae
Name Description Probability Func Analog Organism
GDI1 Gdi1p 0.678
RHO1 Rho1p 0.581
ROM2 Rom2p 0.565
TFB4 Tfb4p 0.531
STI1 Sti1p 0.491
YPT52 Ypt52p 0.462
BEM3 Bem3p 0.421
YDJ1 Ydj1p 0.415
SSL1 Ssl1p 0.389
YPT31 Ypt31p 0.324
SEC4 Sec4p 0.317
YCS4 Ycs4p 0.297
SUI3 Sui3p 0.291
VPS15 Vps15p 0.290
YIP3 Yip3p 0.265
STE11 Ste11p 0.260
BEM4 Bem4p 0.252
STE4 Ste4p 0.242
PKH2 Pkh2p 0.242
KEL1 Kel1p 0.237
KIN28 Kin28p 0.221
TOM1 Tom1p 0.220
GYL1 Gyl1p 0.215
CDC24 Cdc24p 0.215
YPT1 Ypt1p 0.210
CCL1 Ccl1p 0.208
RPN1 Rpn1p 0.206
POL3 Pol3p 0.205
SSA4 Ssa4p 0.202
YPT7 Ypt7p 0.189
TFB5 Tfb5p 0.188
CPR6 Cpr6p 0.185
ORC1 Orc1p 0.185
ORC2 Orc2p 0.182
FKH1 Fkh1p 0.181
ISW1 Isw1p 0.178
TFB3 Tfb3p 0.173
RPT3 Rpt3p 0.170
SPA2 Spa2p 0.165
HIF1 Hif1p 0.164
RAD3 Rad3p 0.164
SEC16 Sec16p 0.160
SEC13 Sec13p 0.158
YLR257W hypothetical protein 0.150
RAD4 Rad4p 0.149
BUD6 Bud6p 0.147
BFR1 Bfr1p 0.147
STE2 Ste2p 0.146
FAR1 Far1p 0.146
SEC2 Sec2p 0.146
MKK1 Mkk1p 0.145
YPT10 Ypt10p 0.142
MDS3 Mds3p 0.139
CDC50 Cdc50p 0.136
IRA1 Ira1p 0.134
TFB1 Tfb1p 0.134
VID30 Vid30p 0.133
VPS4 Vps4p 0.133
KOG1 Kog1p 0.131
SWI1 Swi1p 0.130
ITC1 Itc1p 0.128
ACK1 Ack1p 0.128
PRP8 Prp8p 0.125
SEC3 Sec3p 0.125
SAR1 Sar1p 0.125
VPH2 Vph2p 0.123
IOC3 Ioc3p 0.121
RTT106 Rtt106p 0.119
PEX5 Pex5p 0.118
TUS1 Tus1p 0.116
MYO4 Myo4p 0.116
KAR2 Kar2p 0.115
RAS1 Ras1p 0.115
PPH21 Pph21p 0.114
BRO1 Bro1p 0.113
GCD6 Gcd6p 0.111
RLF2 Rlf2p 0.109
BCK1 Bck1p 0.108
APC11 Apc11p 0.107
KSP1 Ksp1p 0.106
SEC21 Sec21p 0.105
SSL2 Ssl2p 0.105
RPG1 Rpg1p 0.104
AST2 Ast2p 0.103
DOP1 Dop1p 0.102
YPT6 Ypt6p 0.102
HHF2 Hhf2p 0.101
GIC2 Gic2p 0.100
AVO1 Avo1p 0.100
CAK1 Cak1p 0.100
YML002W hypothetical protein 0.099
YLR173W hypothetical protein 0.099
CHS1 Chs1p 0.099
VAC7 Vac7p 0.098
ELG1 Elg1p 0.097
RFC1 Rfc1p 0.095
SWR1 Swr1p 0.094
NUP85 Nup85p 0.093
CDS1 Cds1p 0.093
MKK2 Mkk2p 0.092